Pivalic acid

Pivalic acid is a lipid of Fatty Acyls (FA) class. Pivalic acid is associated with abnormalities such as Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Otitis Media and Chronic infectious disease. The involved functions are known as carnitine transport, Uptake, inhibitors, Oxidation and Intestinal Absorption. Pivalic acid often locates in Grey line. The related lipids are pivalic acid and Fatty Acids.

Cross Reference

Introduction

To understand associated biological information of Pivalic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Pivalic acid?

Pivalic acid is suspected in Otitis Media, Renal carnitine transport defect, Carnitine deficiency, Urinary tract infection, Chronic infectious disease and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Pivalic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Otitis Media D010033 12 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Body Weight D001835 333 associated lipids
Psoriasis D011565 47 associated lipids
Urinary Tract Infections D014552 11 associated lipids
Seizures D012640 87 associated lipids
Dermatitis D003872 30 associated lipids
Vitamin E Deficiency D014811 29 associated lipids
Hyperinsulinism D006946 27 associated lipids
Per page 10 20 | Total 14

PubChem Associated disorders and diseases

What pathways are associated with Pivalic acid

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Pivalic acid through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Pivalic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Pivalic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Pivalic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Pivalic acid?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Pivalic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Pivalic acid

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Per page 10 20 50 100 | Total 272
Authors Title Published Journal PubMed Link
Del Rosso JQ and Kircik L A Comprehensive Review of Clocortolone Pivalate 0.1% Cream: Structural Development, Formulation Characteristics, and Studies Supporting Treatment of Corticosteroid-responsive Dermatoses. 2012 J Clin Aesthet Dermatol pmid:22798972
Demory E et al. Fast Pd- and Pd/Cu-catalyzed direct C-H arylation of cyclic nitrones. Application to the synthesis of enantiopure quaternary α-amino esters. 2012 J. Org. Chem. pmid:22946756
Aljaar N et al. Cu-catalyzed reaction of 1,2-dihalobenzenes with 1,3-cyclohexanediones for the synthesis of 3,4-dihydrodibenzo[b,d]furan-1(2H)-ones. 2012 J. Org. Chem. pmid:22917488
Tomkowicz Z et al. Magnetooptical and structural investigations of five dimeric cobalt(II) complexes mimicking metalloenzyme active sites. 2012 Inorg Chem pmid:22621284
Dorofeeva VN et al. 2D porous honeycomb polymers versus discrete nanocubes from trigonal trinuclear complexes and ligands with variable topology. 2012 Chemistry pmid:22407897
Xu W et al. Identification and characterization of three impurities in clocortolone pivalate. 2012 J Pharm Biomed Anal pmid:22264563
Gensch T et al. Snapshot of the palladium(II)-catalyzed oxidative biaryl bond formation by X-ray analysis of the intermediate diaryl palladium(II) complex. 2012 Chemistry pmid:22170766
Shan Y et al. Rapid acyl migration between pyrogallyl 1,2- and 1,3-dipivaloates. 2012 Nat Prod Commun pmid:22545406
Rezanka T et al. Biosynthesis and metabolic pathways of pivalic acid. 2012 Appl. Microbiol. Biotechnol. pmid:22790609
Kuka J et al. A short-term high-dose administration of sodium pivalate impairs pyruvate metabolism without affecting cardiac function. 2012 Cardiovasc. Toxicol. pmid:22539084