4-METHYLPENTANOIC ACID is a lipid of Fatty Acyls (FA) class. The involved functions are known as CoA-transferase activity. 4-methylpentanoic acid often locates in Cytosol. The related lipids are Fatty Acids and alpha-ketocaproic acid.
To understand associated biological information of 4-METHYLPENTANOIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
There are no associated biomedical information in the current reference collection.
We collected disease MeSH terms mapped to the references associated with 4-METHYLPENTANOIC ACID
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus, Type 1 | D003922 | 56 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Occupational Diseases | D009784 | 42 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Clostridium Infections | D003015 | 5 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nakai T et al. | Ligand-induced conformational changes and a reaction intermediate in branched-chain 2-oxo acid dehydrogenase (E1) from Thermus thermophilus HB8, as revealed by X-ray crystallography. | 2004 | J. Mol. Biol. | pmid:15033367 |
| Broadbent JR et al. | Overexpression of Lactobacillus casei D-hydroxyisocaproic acid dehydrogenase in cheddar cheese. | 2004 | Appl. Environ. Microbiol. | pmid:15294819 |
| Tokuda C et al. | Conversion of Lactobacillus pentosus D-lactate dehydrogenase to a D-hydroxyisocaproate dehydrogenase through a single amino acid replacement. | 2003 | J. Bacteriol. | pmid:12897026 |
| St-Onge MP et al. | Kefir consumption does not alter plasma lipid levels or cholesterol fractional synthesis rates relative to milk in hyperlipidemic men: a randomized controlled trial [ISRCTN10820810]. | 2002 | BMC Complement Altern Med | pmid:11825344 |
| Halvatsiotis PG et al. | Insulin effect on leucine kinetics in type 2 diabetes mellitus. | 2002 | Diabetes Nutr. Metab. | pmid:12173727 |
| Loganath A et al. | Evidence for the biosynthesis of DHEA from cholesterol by first-trimester human placental tissue: source of androgens. | 2002 | Horm. Metab. Res. | pmid:11972299 |
| Crespo-Facorro B et al. | Neural mechanisms of anhedonia in schizophrenia: a PET study of response to unpleasant and pleasant odors. | 2001 | JAMA | pmid:11466121 |
| Okada K et al. | Structures of Escherichia coli branched-chain amino acid aminotransferase and its complexes with 4-methylvalerate and 2-methylleucine: induced fit and substrate recognition of the enzyme. | 2001 | Biochemistry | pmid:11412098 |
| Calzada L et al. | Measurement of androgen and estrogen receptors in breast tissue from subjects with anabolic steroid-dependent gynecomastia. | 2001 | Life Sci. | pmid:11554608 |
| Gunasegaram R et al. | Cytochrome P-450 cholesterol side-chain cleavage expression in human spermatozoa. | 1998 | Horm. Metab. Res. | pmid:9503041 |