2,2-DIMETHYLBUTYRIC ACID

2,2-DIMETHYLBUTYRIC ACID is a lipid of Fatty Acyls (FA) class. The involved functions are known as Fermentation, Process, Intestinal Absorption, Energy Metabolism and Proteolysis. 2,2-dimethylbutyric acid often locates in host and Hepatic. The related lipids are Propionate, Butyrates, n-Butyrate, Valerates and blood lipid.

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Introduction

To understand associated biological information of 2,2-DIMETHYLBUTYRIC ACID, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2,2-DIMETHYLBUTYRIC ACID?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2,2-DIMETHYLBUTYRIC ACID

MeSH term MeSH ID Detail
Gastritis D005756 27 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Sickle Cell Trait D012805 4 associated lipids
beta-Thalassemia D017086 5 associated lipids
Total 4

PubChem Associated disorders and diseases

What pathways are associated with 2,2-DIMETHYLBUTYRIC ACID

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2,2-DIMETHYLBUTYRIC ACID?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 2,2-DIMETHYLBUTYRIC ACID?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 2,2-DIMETHYLBUTYRIC ACID?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 2,2-DIMETHYLBUTYRIC ACID?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with 2,2-DIMETHYLBUTYRIC ACID?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 2,2-DIMETHYLBUTYRIC ACID

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Authors Title Published Journal PubMed Link
pmid:
Uchiyama N et al. Metabolic fate of 2,2-dimethylbutyryl moiety of simvastatin in rats: identification of metabolites by gas chromatography/mass spectrometry. 1991 Jul-Sep Eur J Drug Metab Pharmacokinet pmid:1814736
Krishna S et al. Differential effects of short-chain fatty acids on head and neck squamous carcinoma cells. 2002 Laryngoscope pmid:12150517
Stiefl N and Baumann K Mapping property distributions of molecular surfaces: algorithm and evaluation of a novel 3D quantitative structure-activity relationship technique. 2003 J. Med. Chem. pmid:12672239
Tang YL et al. [Chemical components of essential oils from the herb of Ligularia virgaurea]. 2003 Zhongguo Zhong Yao Za Zhi pmid:15139106
Cejka J et al. Simvastatin. 2003 Acta Crystallogr C pmid:12909768
Chakov NE et al. New polynuclear manganese clusters from the use of the hydrophobic carboxylate ligand 2,2-dimethylbutyrate. 2005 Inorg Chem pmid:15962962
Nguyen TD et al. Novel short chain fatty acids restore chloride secretion in cystic fibrosis. 2006 Biochem. Biophys. Res. Commun. pmid:16472777
Martin FP et al. A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model. 2007 Mol. Syst. Biol. pmid:17515922
Martin FP et al. Top-down systems biology integration of conditional prebiotic modulated transgenomic interactions in a humanized microbiome mouse model. 2008 Mol. Syst. Biol. pmid:18628745