10-Deoxymethynolide

10-Deoxymethynolide is a lipid of Polyketides (PK) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 115 references associated with 10-Deoxymethynolide in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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All references with 10-Deoxymethynolide

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Authors Title Published Journal PubMed Link
Koryakina I et al. Inversion of Extender Unit Selectivity in the Erythromycin Polyketide Synthase by Acyltransferase Domain Engineering. 2017 ACS Chem. Biol. pmid:28103677
Xuan R et al. Total synthesis of 10-deoxymethynolide and narbonolide. 2008 J. Org. Chem. pmid:18205385
Pageni BB et al. Metabolic engineering of noviose: heterologous expression of novWUS and generation of a new hybrid antibiotic, noviosylated 10-deoxymethynolide/narbonolide, from Streptomyces venezuelae YJ003-OTBP1. 2008 Biotechnol. Lett. pmid:18427928
Akey DL et al. Structural basis for macrolactonization by the pikromycin thioesterase. 2006 Nat. Chem. Biol. pmid:16969372
Giraldes JW et al. Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels. 2006 Nat. Chem. Biol. pmid:16969373
He W et al. Macrolactonization to 10-deoxymethynolide catalyzed by the recombinant thioesterase of the picromycin/methymycin polyketide synthase. 2006 Bioorg. Med. Chem. Lett. pmid:16249083
Aldrich CC et al. Chemoenzymatic synthesis of the polyketide macrolactone 10-deoxymethynolide. 2005 J. Am. Chem. Soc. pmid:15969542
Beck BJ et al. The hidden steps of domain skipping: macrolactone ring size determination in the pikromycin modular polyketide synthase. 2002 Chem. Biol. pmid:12031664
Chen S et al. The Streptomyces venezuelae pikAV gene contains a transcription unit essential for expression of enzymes involved in glycosylation of narbonolide and 10-deoxymethynolide. 2001 Gene pmid:11223265
Chen S et al. Mechanisms of molecular recognition in the pikromycin polyketide synthase. 2000 Chem. Biol. pmid:11137814