Delphinidin

Delphinidin is a lipid of Polyketides (PK) class. Delphinidin is associated with abnormalities such as Virus Diseases, Chronic disease, Inflammatory disorder, Degenerative polyarthritis and Cardiovascular Diseases. The involved functions are known as Signal Pathways, Metabolic Inhibition, Signal Transduction, Cell Proliferation and Cell Death. Delphinidin often locates in Tissue membrane, Tubulo-reticular structure, Smooth muscle (tissue), Endothelium and soluble. The associated genes with Delphinidin are KDR gene, P4HTM gene, IRAK1 gene, MAPK14 wt Allele and ADAMTS3 gene. The related lipids are Steroids, Total cholesterol and saikosaponin B2. The related experimental models are Xenograft Model, Knock-out, Disease model and Animal Disease Models.

Cross Reference

Introduction

To understand associated biological information of Delphinidin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Delphinidin?

Delphinidin is suspected in Chronic disease, Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Cardiovascular Diseases, Virus Diseases, Inflammatory disorder and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Delphinidin

MeSH term MeSH ID Detail
Diabetes Mellitus D003920 90 associated lipids
Lung Neoplasms D008175 171 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Body Weight D001835 333 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Thrombosis D013927 49 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Lymphatic Metastasis D008207 10 associated lipids
Mammary Neoplasms, Animal D015674 27 associated lipids
Total 10

PubChem Associated disorders and diseases

What pathways are associated with Delphinidin

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Delphinidin?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Delphinidin?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Delphinidin?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Delphinidin?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Delphinidin?

Xenograft Model

Xenograft Model are used in the study 'A dietary anthocyanidin delphinidin induces apoptosis of human prostate cancer PC3 cells in vitro and in vivo: involvement of nuclear factor-kappaB signaling.' (Hafeez BB et al., 2008).

Knock-out

Knock-out are used in the study 'MATE2 mediates vacuolar sequestration of flavonoid glycosides and glycoside malonates in Medicago truncatula.' (Zhao J et al., 2011) and Knock-out are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).

Disease model

Disease model are used in the study 'How can research on plants contribute to promoting human health?' (Martin C et al., 2011).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Delphinidin

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Authors Title Published Journal PubMed Link
Chen J et al. Delphinidin protects β2m-/Thy1+ bone marrow-derived hepatocyte stem cells against TGF-β1-induced oxidative stress and apoptosis through the PI3K/Akt pathway in vitro. 2019 Chem. Biol. Interact. pmid:30365941
Bankoglu EE et al. Protective effects of tricetinidin against oxidative stress inducers in rat kidney cells: A comparison with delphinidin and standard antioxidants. 2018 Food Chem. Toxicol. pmid:30266311
Łata E et al. Vulnerability of anthocyanins to the components of a thin-layer chromatographic system and comprehensive screening of anthocyanes in alimentary products. 2018 J Chromatogr A pmid:30150119
Yoshino Y et al. Enhanced cytotoxic effects of arsenite in combination with anthocyanidin compound, delphinidin, against a human leukemia cell line, HL-60. 2018 Chem. Biol. Interact. pmid:30125548
Parra-Vargas M et al. Delphinidin Ameliorates Hepatic Triglyceride Accumulation in Human HepG2 Cells, but Not in Diet-Induced Obese Mice. 2018 Nutrients pmid:30103390
Yue Q et al. Characterization of Gene Expression Profile, Phenolic Composition, and Antioxidant Capacity in Red-Fleshed Grape Berries and Their Wines. 2018 J. Agric. Food Chem. pmid:29920074
Daveri E et al. Cyanidin and delphinidin modulate inflammation and altered redox signaling improving insulin resistance in high fat-fed mice. 2018 Redox Biol pmid:29890336
Zykin PA et al. Anthocyanin Composition and Content in Rye Plants with Different Grain Color. 2018 Molecules pmid:29671758
Kang HM et al. Delphinidin induces apoptosis and inhibits epithelial-to-mesenchymal transition via the ERK/p38 MAPK-signaling pathway in human osteosarcoma cell lines. 2018 Environ. Toxicol. pmid:29451351
Aichinger G et al. Delphinidin protects colon carcinoma cells against the genotoxic effects of the mycotoxin altertoxin II. 2018 Toxicol. Lett. pmid:29217480