Valeric acid is a lipid of Fatty Acyls (FA) class. Valeric acid is associated with abnormalities such as Papillon-Lefevre Disease, Obesity, Diabetes Mellitus, Non-Insulin-Dependent and Dehydration. The involved functions are known as Process, Odorant, Stimulus, Irritation and Phenomenon. Valeric acid often locates in Receptive field, soluble, Extracellular, Entire gastrointestinal tract and Body tissue. The associated genes with Valeric acid are Orthologous Gene, Fusion Gene and AS gene. The related lipids are Valerates, butyrate, Propionate, Caproates and Palmitates.
To understand associated biological information of Valeric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Valeric acid is suspected in Obesity, Papillon-Lefevre Disease, Diabetes Mellitus, Non-Insulin-Dependent, Dehydration and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with Valeric acid
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Stomach Ulcer | D013276 | 75 associated lipids |
| Dermatitis, Contact | D003877 | 59 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Glioma | D005910 | 112 associated lipids |
| Peripheral Nervous System Diseases | D010523 | 33 associated lipids |
| Arthritis, Infectious | D001170 | 8 associated lipids |
| Anemia, Sickle Cell | D000755 | 34 associated lipids |
| Psoriasis | D011565 | 47 associated lipids |
| Reye Syndrome | D012202 | 14 associated lipids |
| Uterine Hemorrhage | D014592 | 6 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
| Gene | Cross reference | Weighted score | Related literatures |
|---|
There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
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| Kalbe B et al. | Olfactory signaling components and olfactory receptors are expressed in tubule cells of the human kidney. | 2016 | Arch. Biochem. Biophys. | pmid:27693121 |
| Cal AJ et al. | Methanotrophic production of polyhydroxybutyrate-co-hydroxyvalerate with high hydroxyvalerate content. | 2016 | Int. J. Biol. Macromol. | pmid:26920242 |
| Moen B et al. | Extrusion of barley and oat influence the fecal microbiota and SCFA profile of growing pigs. | 2016 | Food Funct | pmid:26758043 |
| Park JH et al. | Valeric acid induces cell cycle arrest at G1 phase in CHO cell cultures and improves recombinant antibody productivity. | 2016 | Biotechnol J | pmid:26663903 |
| Stang C and Harnisch F | The Dilemma of Supporting Electrolytes for Electroorganic Synthesis: A Case Study on Kolbe Electrolysis. | 2016 | ChemSusChem | pmid:26609800 |
| Ventrella D et al. | Age-Related 1H NMR Characterization of Cerebrospinal Fluid in Newborn and Young Healthy Piglets. | 2016 | PLoS ONE | pmid:27391145 |
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| Park M et al. | Determination of XLR-11 and its metabolites in hair by liquid chromatography-tandem mass spectrometry. | 2015 | J Pharm Biomed Anal | pmid:26070160 |
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| Sakamoto O et al. | Phenotypic Variability and Newly Identified Mutations of the IVD Gene in Japanese Patients with Isovaleric Acidemia. | 2015 | Tohoku J. Exp. Med. | pmid:26018748 |
| Gołąb K et al. | Improved coating of pancreatic islets with regulatory T cells to create local immunosuppression by using the biotin-polyethylene glycol-succinimidyl valeric acid ester molecule. | 2014 Jul-Aug | Transplant. Proc. | pmid:25131084 |
| Varga K et al. | Histone deacetylase inhibitor- and PMA-induced upregulation of PMCA4b enhances Ca2+ clearance from MCF-7 breast cancer cells. | 2014 | Cell Calcium | pmid:24439526 |
| Takagaki A et al. | Isolation and characterization of rat intestinal bacteria involved in biotransformation of (-)-epigallocatechin. | 2014 | Arch. Microbiol. | pmid:24947740 |
| Verhoeven E et al. | Pink urine. | 2014 | Clin Toxicol (Phila) | pmid:25233954 |
| Sayin S et al. | Enhanced catalysis and enantioselective resolution of racemic naproxen methyl ester by lipase encapsulated within iron oxide nanoparticles coated with calix[8]arene valeric acid complexes. | 2014 | Org. Biomol. Chem. | pmid:25012138 |
| Han JH et al. | The effects of propionate and valerate on insulin responsiveness for glucose uptake in 3T3-L1 adipocytes and C2C12 myotubes via G protein-coupled receptor 41. | 2014 | PLoS ONE | pmid:24748202 |
| Hand KV et al. | Examining acute and chronic effects of short- and long-chain fatty acids on peptide YY (PYY) gene expression, cellular storage and secretion in STC-1 cells. | 2013 | Eur J Nutr | pmid:22926626 |
| Špoljarić IV et al. | Mathematical modeling of poly[(R)-3-hydroxyalkanoate] synthesis by Cupriavidus necator DSM 545 on substrates stemming from biodiesel production. | 2013 | Bioresour. Technol. | pmid:23454805 |
| Xin L et al. | Electricity storage in biofuels: selective electrocatalytic reduction of levulinic acid to valeric acid or γ-valerolactone. | 2013 | ChemSusChem | pmid:23457116 |
| Jang M et al. | Monitoring of urinary metabolites of JWH-018 and JWH-073 in legal cases. | 2013 | Forensic Sci. Int. | pmid:23890611 |
| Takagaki A and Nanjo F | Catabolism of (+)-catechin and (-)-epicatechin by rat intestinal microbiota. | 2013 | J. Agric. Food Chem. | pmid:23621128 |
| Emerson B et al. | Gas chromatography-mass spectrometry of JWH-018 metabolites in urine samples with direct comparison to analytical standards. | 2013 | Forensic Sci. Int. | pmid:23683902 |
| Fischer D et al. | The repelling effect of plant secondary metabolites on water voles, Arvicola amphibius. | 2013 | Pest Manag. Sci. | pmid:23225271 |
| Brasili E et al. | Lactobacillus acidophilus La5 and Bifidobacterium lactis Bb12 induce different age-related metabolic profiles revealed by 1H-NMR spectroscopy in urine and feces of mice. | 2013 | J. Nutr. | pmid:23946343 |
| Rico CM et al. | Effect of cerium oxide nanoparticles on the quality of rice ( Oryza sativa L.) grains. | 2013 | J. Agric. Food Chem. | pmid:24188281 |
| Jiang W et al. | Differential regulation of human cathelicidin LL-37 by free fatty acids and their analogs. | 2013 | Peptides | pmid:24140860 |
| Yoneda S et al. | Effects of short-chain fatty acids on Actinomyces naeslundii biofilm formation. | 2013 | Mol Oral Microbiol | pmid:23731652 |
| Jakobsdottir G et al. | Fasting serum concentration of short-chain fatty acids in subjects with microscopic colitis and celiac disease: no difference compared with controls, but between genders. | 2013 | Scand. J. Gastroenterol. | pmid:23600961 |
| Moita R and Lemos PC | Biopolymers production from mixed cultures and pyrolysis by-products. | 2012 | J. Biotechnol. | pmid:21983233 |
| Reimer RA et al. | Faecal short chain fatty acids in healthy subjects participating in a randomised controlled trial examining a soluble highly viscous polysaccharide versus control. | 2012 | J Hum Nutr Diet | pmid:22320902 |
| Jensen JM et al. | Gene expression is differently affected by pimecrolimus and betamethasone in lesional skin of atopic dermatitis. | 2012 | Allergy | pmid:22142306 |
| Grégoire P et al. | Desulfosoma profundi sp. nov., a thermophilic sulfate-reducing bacterium isolated from a deep terrestrial geothermal spring in France. | 2012 | Antonie Van Leeuwenhoek | pmid:22120904 |
| Tyndall V et al. | Effect of androgen treatment during foetal and/or neonatal life on ovarian function in prepubertal and adult rats. | 2012 | Reproduction | pmid:22016380 |
| Chee JY et al. | Expression of Aeromonas caviae polyhydroxyalkanoate synthase gene in Burkholderia sp. USM (JCM15050) enables the biosynthesis of SCL-MCL PHA from palm oil products. | 2012 | J. Appl. Microbiol. | pmid:22054430 |
| Qiao X et al. | A tandem mass spectrometric study of bile acids: interpretation of fragmentation pathways and differentiation of steroid isomers. | 2012 | Steroids | pmid:22133544 |
| Chang HF et al. | Synthesis of poly(3-hydroxybutyrate/3-hydroxyvalerate) from propionate-fed activated sludge under various carbon sources. | 2012 | Bioresour. Technol. | pmid:22277212 |
| Kilner J et al. | A proteomic analysis of differential cellular responses to the short-chain fatty acids butyrate, valerate and propionate in colon epithelial cancer cells. | 2012 | Mol Biosyst | pmid:22075547 |
| Banel A et al. | Determination of SCFAs in water using GC-FID. Selection of the separation system. | 2012 | Anal. Chim. Acta | pmid:22284873 |