|MeSH term||MeSH ID||Detail|
|Melanoma||D008545||69 associated lipids|
Dimethylallyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Dimethylallyl pyrophosphate is associated with abnormalities such as Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as Anabolism, Biochemical Pathway, Oxidation, Process and Chelating Activity [MoA]. Dimethylallyl pyrophosphate often locates in Chloroplasts, Plastids, chloroplast stroma, Cytosol and Cell membrane. The associated genes with Dimethylallyl pyrophosphate are IRF6 wt Allele and ADRBK1 gene. The related lipids are Sterols.
To understand associated biological information of Dimethylallyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Dimethylallyl pyrophosphate is suspected in and other diseases in descending order of the highest number of associated sentences.
|Disease||Cross reference||Weighted score||Related literature|
We collected disease MeSH terms mapped to the references associated with Dimethylallyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Dimethylallyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
|Pathway name||Related literatures|
Associated locations are in red color. Not associated locations are in black.
|Function||Cross reference||Weighted score||Related literatures|
|Lipid concept||Cross reference||Weighted score||Related literatures|
There are no associated biomedical information in the current reference collection.
|Yang L et al.||Combinatorial engineering of hybrid mevalonate pathways in Escherichia coli for protoilludene production.||2016||Microb. Cell Fact.||pmid:26785630|
|Yang T et al.||A Stilbenoid-Specific Prenyltransferase Utilizes Dimethylallyl Pyrophosphate from the Plastidic Terpenoid Pathway.||2016||Plant Physiol.||pmid:27356974|
|Banerjee A et al.||Engineering of Recombinant Poplar Deoxy-D-Xylulose-5-Phosphate Synthase (PtDXS) by Site-Directed Mutagenesis Improves Its Activity.||2016||PLoS ONE||pmid:27548482|
|Ge D et al.||Two unexpected promiscuous activities of the iron-sulfur protein IspH in production of isoprene and isoamylene.||2016||Microb. Cell Fact.||pmid:27169371|
|Dong L et al.||Monoterpene biosynthesis potential of plant subcellular compartments.||2016||New Phytol.||pmid:26356766|
|Henry LK et al.||Orthologs of the archaeal isopentenyl phosphate kinase regulate terpenoid production in plants.||2015||Proc. Natl. Acad. Sci. U.S.A.||pmid:26216978|
|Sharon C et al.||Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo.||2015||Oncotarget||pmid:25895029|
|Fan A et al.||Site-directed mutagenesis switching a dimethylallyl tryptophan synthase to a specific tyrosine C3-prenylating enzyme.||2015||J. Biol. Chem.||pmid:25477507|
|Wiley JD et al.||Isoprenoid precursor biosynthesis is the essential metabolic role of the apicoplast during gametocytogenesis in Plasmodium falciparum.||2015||Eukaryotic Cell||pmid:25446055|
|Teufel R et al.||One-pot enzymatic synthesis of merochlorin A and B.||2014||Angew. Chem. Int. Ed. Engl.||pmid:25115835|