Dimethylallyl pyrophosphate

Dimethylallyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Dimethylallyl pyrophosphate is associated with abnormalities such as Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as Anabolism, Biochemical Pathway, Oxidation, Process and Chelating Activity [MoA]. Dimethylallyl pyrophosphate often locates in Chloroplasts, Plastids, chloroplast stroma, Cytosol and Cell membrane. The associated genes with Dimethylallyl pyrophosphate are IRF6 wt Allele and ADRBK1 gene. The related lipids are Sterols.

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Introduction

To understand associated biological information of Dimethylallyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Dimethylallyl pyrophosphate?

Dimethylallyl pyrophosphate is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Dimethylallyl pyrophosphate

MeSH term MeSH ID Detail
Melanoma D008545 69 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Dimethylallyl pyrophosphate

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Dimethylallyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.

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PubChem Biomolecular Interactions and Pathways

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What cellular locations are associated with Dimethylallyl pyrophosphate?

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What functions are associated with Dimethylallyl pyrophosphate?


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What lipids are associated with Dimethylallyl pyrophosphate?

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What genes are associated with Dimethylallyl pyrophosphate?

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Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Dimethylallyl pyrophosphate?

There are no associated biomedical information in the current reference collection.

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All references with Dimethylallyl pyrophosphate

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Authors Title Published Journal PubMed Link
Yang L et al. Combinatorial engineering of hybrid mevalonate pathways in Escherichia coli for protoilludene production. 2016 Microb. Cell Fact. pmid:26785630
Yang T et al. A Stilbenoid-Specific Prenyltransferase Utilizes Dimethylallyl Pyrophosphate from the Plastidic Terpenoid Pathway. 2016 Plant Physiol. pmid:27356974
Banerjee A et al. Engineering of Recombinant Poplar Deoxy-D-Xylulose-5-Phosphate Synthase (PtDXS) by Site-Directed Mutagenesis Improves Its Activity. 2016 PLoS ONE pmid:27548482
Ge D et al. Two unexpected promiscuous activities of the iron-sulfur protein IspH in production of isoprene and isoamylene. 2016 Microb. Cell Fact. pmid:27169371
Dong L et al. Monoterpene biosynthesis potential of plant subcellular compartments. 2016 New Phytol. pmid:26356766
Henry LK et al. Orthologs of the archaeal isopentenyl phosphate kinase regulate terpenoid production in plants. 2015 Proc. Natl. Acad. Sci. U.S.A. pmid:26216978
Sharon C et al. Inhibition of insulin-like growth factor receptor/AKT/mammalian target of rapamycin axis targets colorectal cancer stem cells by attenuating mevalonate-isoprenoid pathway in vitro and in vivo. 2015 Oncotarget pmid:25895029
Fan A et al. Site-directed mutagenesis switching a dimethylallyl tryptophan synthase to a specific tyrosine C3-prenylating enzyme. 2015 J. Biol. Chem. pmid:25477507
Wiley JD et al. Isoprenoid precursor biosynthesis is the essential metabolic role of the apicoplast during gametocytogenesis in Plasmodium falciparum. 2015 Eukaryotic Cell pmid:25446055
Liu C et al. Functional analysis of a prenyltransferase gene (paxD) in the paxilline biosynthetic gene cluster. 2014 Appl. Microbiol. Biotechnol. pmid:23525886
Banerjee A and Sharkey TD Methylerythritol 4-phosphate (MEP) pathway metabolic regulation. 2014 Nat Prod Rep pmid:24921065
Rasulov B et al. Competition between isoprene emission and pigment synthesis during leaf development in aspen. 2014 Plant Cell Environ. pmid:24033429
Jakubczyk D et al. Biosynthesis of the ergot alkaloids. 2014 Nat Prod Rep pmid:25164781
Pan LL et al. Origin of product selectivity in a prenyl transfer reaction from the same intermediate: exploration of multiple FtmPT1-catalyzed prenyl transfer pathways. 2014 Biochemistry pmid:25188320
Krasutsky SG et al. Synthesis of methylerythritol phosphate analogues and their evaluation as alternate substrates for IspDF and IspE from Agrobacterium tumefaciens. 2014 J. Org. Chem. pmid:25184438
Heider SA et al. IdsA is the major geranylgeranyl pyrophosphate synthase involved in carotenogenesis in Corynebacterium glutamicum. 2014 FEBS J. pmid:25181035
Teufel R et al. One-pot enzymatic synthesis of merochlorin A and B. 2014 Angew. Chem. Int. Ed. Engl. pmid:25115835
Fox DT et al. Sub-inhibitory fosmidomycin exposures elicits oxidative stress in Salmonella enterica serovar Typhimurium LT2. 2014 PLoS ONE pmid:24751777
Ghirardo A et al. Metabolic flux analysis of plastidic isoprenoid biosynthesis in poplar leaves emitting and nonemitting isoprene. 2014 Plant Physiol. pmid:24590857
Banerjee A et al. Feedback inhibition of deoxy-D-xylulose-5-phosphate synthase regulates the methylerythritol 4-phosphate pathway. 2013 J. Biol. Chem. pmid:23612965
Arens J et al. Exploration of biosynthetic access to the shared precursor of the fusicoccane diterpenoid family. 2013 Chem. Commun. (Camb.) pmid:23295536
Ueno A et al. Farsenyl pyrophosphate synthase is a potential molecular drug target of risedronate in Babesia bovis. 2013 Parasitol. Int. pmid:23276703
Weise SE et al. Measuring dimethylallyl diphosphate available for isoprene synthesis. 2013 Anal. Biochem. pmid:23262281
Zhao L et al. Methylerythritol phosphate pathway of isoprenoid biosynthesis. 2013 Annu. Rev. Biochem. pmid:23746261
Zhou C et al. Isopentenyl diphosphate and dimethylallyl diphosphate/isopentenyl diphosphate ratio measured with recombinant isopentenyl diphosphate isomerase and isoprene synthase. 2013 Anal. Biochem. pmid:23747531
Chen X et al. Statistical experimental design guided optimization of a one-pot biphasic multienzyme total synthesis of amorpha-4,11-diene. 2013 PLoS ONE pmid:24278153
Chang WC et al. Current development in isoprenoid precursor biosynthesis and regulation. 2013 Curr Opin Chem Biol pmid:23891475
Rudolf JD and Poulter CD Tyrosine O-prenyltransferase SirD catalyzes S-, C-, and N-prenylations on tyrosine and tryptophan derivatives. 2013 ACS Chem. Biol. pmid:24083562
Sun Z et al. Can the capacity for isoprene emission acclimate to environmental modifications during autumn senescence in temperate deciduous tree species Populus tremula? 2012 J. Plant Res. pmid:21584787
Yang J et al. Enhancing production of bio-isoprene using hybrid MVA pathway and isoprene synthase in E. coli. 2012 PLoS ONE pmid:22558074
Ma Y et al. Genome-wide identification and characterization of novel genes involved in terpenoid biosynthesis in Salvia miltiorrhiza. 2012 J. Exp. Bot. pmid:22291132
Span I et al. Crystal structures of mutant IspH proteins reveal a rotation of the substrate's hydroxymethyl group during catalysis. 2012 J. Mol. Biol. pmid:22137895
Angaman DM et al. Precursor uptake assays and metabolic analyses in isolated tomato fruit chromoplasts. 2012 Plant Methods pmid:22243738
Yu X et al. Biochemical characterization of indole prenyltransferases: filling the last gap of prenylation positions by a 5-dimethylallyltryptophan synthase from Aspergillus clavatus. 2012 J. Biol. Chem. pmid:22123822
Xu W et al. A closer look at the spectroscopic properties of possible reaction intermediates in wild-type and mutant (E)-4-hydroxy-3-methylbut-2-enyl diphosphate reductase. 2012 Biochemistry pmid:22646150
Fu X et al. Plastid structure and carotenogenic gene expression in red- and white-fleshed loquat (Eriobotrya japonica) fruits. 2012 J. Exp. Bot. pmid:21994170
Wollinsky B et al. Prenylation at the indole ring leads to a significant increase of cytotoxicity of tryptophan-containing cyclic dipeptides. 2012 Bioorg. Med. Chem. Lett. pmid:22617493
Bang S et al. Nociceptive and pro-inflammatory effects of dimethylallyl pyrophosphate via TRPV4 activation. 2012 Br. J. Pharmacol. pmid:22300296
Qian Q et al. Mechanistic studies on CymD: a tryptophan reverse N-prenyltransferase. 2012 Biochemistry pmid:22935004
Behr M et al. Remodeling of cytokinin metabolism at infection sites of Colletotrichum graminicola on maize leaves. 2012 Mol. Plant Microbe Interact. pmid:22746825
Testa CA and Johnson LJ A whole-cell phenotypic screening platform for identifying methylerythritol phosphate pathway-selective inhibitors as novel antibacterial agents. 2012 Antimicrob. Agents Chemother. pmid:22777049
Lu XM et al. Map-based cloning of zb7 encoding an IPP and DMAPP synthase in the MEP pathway of maize. 2012 Mol Plant pmid:22498772
Nakatani H et al. Substrate-induced change in the quaternary structure of type 2 isopentenyl diphosphate isomerase from Sulfolobus shibatae. 2012 J. Bacteriol. pmid:22505674
Song AA et al. Functional expression of an orchid fragrance gene in Lactococcus lactis. 2012 Int J Mol Sci pmid:22408409
Wollinsky B et al. Breaking the regioselectivity of indole prenyltransferases: identification of regular C3-prenylated hexahydropyrrolo[2,3-b]indoles as side products of the regular C2-prenyltransferase FtmPT1. 2012 Org. Biomol. Chem. pmid:23090579
Nagel R et al. Nonradioactive assay for detecting isoprenyl diphosphate synthase activity in crude plant extracts using liquid chromatography coupled with tandem mass spectrometry. 2012 Anal. Biochem. pmid:22266300
Green SA et al. Identification, functional characterization, and regulation of the enzyme responsible for floral (E)-nerolidol biosynthesis in kiwifruit (Actinidia chinensis). 2012 J. Exp. Bot. pmid:22162874
Zhang YL and Li ZX Functional analysis and molecular docking identify two active short-chain prenyltransferases in the green peach aphid, Myzus persicae. 2012 Arch. Insect Biochem. Physiol. pmid:22696503
Faraldos JA et al. Probing the mechanism of 1,4-conjugate elimination reactions catalyzed by terpene synthases. 2012 J. Am. Chem. Soc. pmid:23214943
Span I et al. Discovery of acetylene hydratase activity of the iron-sulphur protein IspH. 2012 Nat Commun pmid:22948824
Bitok JK and Meyers CF 2C-Methyl-d-erythritol 4-phosphate enhances and sustains cyclodiphosphate synthase IspF activity. 2012 ACS Chem. Biol. pmid:22839733
Diaz ME et al. Characterization of an isopentenyl diphosphate isomerase involved in the juvenile hormone pathway in Aedes aegypti. 2012 Insect Biochem. Mol. Biol. pmid:22782071
Gonzales-Vigil E et al. Evolution of TPS20-related terpene synthases influences chemical diversity in the glandular trichomes of the wild tomato relative Solanum habrochaites. 2012 Plant J. pmid:22563774
Kuzuyama T and Seto H Two distinct pathways for essential metabolic precursors for isoprenoid biosynthesis. 2012 Proc. Jpn. Acad., Ser. B, Phys. Biol. Sci. pmid:22450534
Trowbridge AM et al. Contribution of various carbon sources toward isoprene biosynthesis in poplar leaves mediated by altered atmospheric CO2 concentrations. 2012 PLoS ONE pmid:22384238
Yang ZB et al. Physiological and molecular analysis of the interaction between aluminium toxicity and drought stress in common bean (Phaseolus vulgaris). 2012 J. Exp. Bot. pmid:22371077
Wu S et al. Engineering triterpene metabolism in tobacco. 2012 Planta pmid:22729821
Dozier JK and Distefano MD An enzyme-coupled continuous fluorescence assay for farnesyl diphosphate synthases. 2012 Anal. Biochem. pmid:22085443
Caballero MC et al. Characterization of acyl carrier protein and LytB in Babesia bovis apicoplast. 2012 Mol. Biochem. Parasitol. pmid:22057350
Fowler DW et al. Mycobacteria activate γδ T-cell anti-tumour responses via cytokines from type 1 myeloid dendritic cells: a mechanism of action for cancer immunotherapy. 2012 Cancer Immunol. Immunother. pmid:22002242
Türsen U Pathophysiology of the Behçet's Disease. 2012 Patholog Res Int pmid:21977335
Hussain MS et al. Current approaches toward production of secondary plant metabolites. 2012 J Pharm Bioallied Sci pmid:22368394
Lamsen EN and Atsumi S Recent progress in synthetic biology for microbial production of C3-C10 alcohols. 2012 Front Microbiol pmid:22701113
Aros D et al. Volatile emissions of scented Alstroemeria genotypes are dominated by terpenes, and a myrcene synthase gene is highly expressed in scented Alstroemeria flowers. 2012 J. Exp. Bot. pmid:22268153
Fatima T et al. Fatty acid composition of developing sea buckthorn (Hippophae rhamnoides L.) berry and the transcriptome of the mature seed. 2012 PLoS ONE pmid:22558083
Thabet I et al. Characterization and subcellular localization of geranylgeranyl diphosphate synthase from Catharanthus roseus. 2012 Mol. Biol. Rep. pmid:21706164
Tidten-Luksch N et al. IspE inhibitors identified by a combination of in silico and in vitro high-throughput screening. 2012 PLoS ONE pmid:22563402
Suzuki N et al. Construction and analysis of EST libraries of the trans-polyisoprene producing plant, Eucommia ulmoides Oliver. 2012 Planta pmid:22729820
Jonnalagadda V et al. Isopentenyl diphosphate isomerase catalyzed reactions in D2O: product release limits the rate of this sluggish enzyme-catalyzed reaction. 2012 J. Am. Chem. Soc. pmid:22471428
Berthelot K et al. Isopentenyl diphosphate isomerase: A checkpoint to isoprenoid biosynthesis. 2012 Biochimie pmid:22503704
Fischer MJ et al. Identification of a lysine residue important for the catalytic activity of yeast farnesyl diphosphate synthase. 2011 Protein J. pmid:21643844
Hunter WN Isoprenoid precursor biosynthesis offers potential targets for drug discovery against diseases caused by apicomplexan parasites. 2011 Curr Top Med Chem pmid:21619509
Hemmi H [Unique flavoenzyme: type 2 isopentenyl diphosphate isomerase]. 2011 Seikagaku pmid:21626882
Brilli F et al. Detection of plant volatiles after leaf wounding and darkening by proton transfer reaction "time-of-flight" mass spectrometry (PTR-TOF). 2011 PLoS ONE pmid:21637822
Mann FM et al. Rv0989c encodes a novel (E)-geranyl diphosphate synthase facilitating decaprenyl diphosphate biosynthesis in Mycobacterium tuberculosis. 2011 FEBS Lett. pmid:21237161
Li Z et al. Effect of temperature on postillumination isoprene emission in oak and poplar. 2011 Plant Physiol. pmid:21177471
Heaps NA and Poulter CD Synthesis and evaluation of chlorinated substrate analogues for farnesyl diphosphate synthase. 2011 J. Org. Chem. pmid:21344952
Atsbaha Zebelo S et al. Chrysolina herbacea modulates terpenoid biosynthesis of Mentha aquatica L. 2011 PLoS ONE pmid:21408066
Odom AR Five questions about non-mevalonate isoprenoid biosynthesis. 2011 PLoS Pathog. pmid:22216001
Thabet I et al. The subcellular localization of periwinkle farnesyl diphosphate synthase provides insight into the role of peroxisome in isoprenoid biosynthesis. 2011 J. Plant Physiol. pmid:21872968
Barrero RA et al. De novo assembly of Euphorbia fischeriana root transcriptome identifies prostratin pathway related genes. 2011 BMC Genomics pmid:22151917
Tijerino A et al. Overexpression of the Trichoderma brevicompactum tri5 gene: effect on the expression of the trichodermin biosynthetic genes and on tomato seedlings. 2011 Toxins (Basel) pmid:22069764
Tsang A et al. Francisella tularensis 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase: kinetic characterization and phosphoregulation. 2011 PLoS ONE pmid:21694781
Heaps NA and Poulter CD Type-2 isopentenyl diphosphate isomerase: evidence for a stepwise mechanism. 2011 J. Am. Chem. Soc. pmid:22047048
Misawa N Carotenoid β-ring hydroxylase and ketolase from marine bacteria-promiscuous enzymes for synthesizing functional xanthophylls. 2011 Mar Drugs pmid:21673887
Umeda T et al. Molecular basis of fosmidomycin's action on the human malaria parasite Plasmodium falciparum. 2011 Sci Rep pmid:22355528
Wen W and Yu R Artemisinin biosynthesis and its regulatory enzymes: Progress and perspective. 2011 Pharmacogn Rev pmid:22279377
Bonitz T et al. Evolutionary relationships of microbial aromatic prenyltransferases. 2011 PLoS ONE pmid:22140437
Muraguchi T et al. Polished rice as natural sources of cancer-preventing geranylgeranoic acid. 2011 J Clin Biochem Nutr pmid:21765600
Clastre M et al. Subcellular evidence for the involvement of peroxisomes in plant isoprenoid biosynthesis. 2011 Plant Signal Behav pmid:22080790
Hao da C et al. The first insight into the tissue specific taxus transcriptome via Illumina second generation sequencing. 2011 PLoS ONE pmid:21731678
Tang Q et al. An efficient approach to finding Siraitia grosvenorii triterpene biosynthetic genes by RNA-seq and digital gene expression analysis. 2011 BMC Genomics pmid:21729270
Davey MS et al. Human neutrophil clearance of bacterial pathogens triggers anti-microbial γδ T cell responses in early infection. 2011 PLoS Pathog. pmid:21589907
Okada K The biosynthesis of isoprenoids and the mechanisms regulating it in plants. 2011 Biosci. Biotechnol. Biochem. pmid:21737944
Baumeister S et al. Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathways. 2011 PLoS ONE pmid:21573242
Gray DW et al. Biochemical characterization and homology modeling of methylbutenol synthase and implications for understanding hemiterpene synthase evolution in plants. 2011 J. Biol. Chem. pmid:21504898
Meier S et al. A transcriptional analysis of carotenoid, chlorophyll and plastidial isoprenoid biosynthesis genes during development and osmotic stress responses in Arabidopsis thaliana. 2011 BMC Syst Biol pmid:21595952
Jang HJ et al. Retinoid production using metabolically engineered Escherichia coli with a two-phase culture system. 2011 Microb. Cell Fact. pmid:21801353
Lemuth K et al. Engineering of a plasmid-free Escherichia coli strain for improved in vivo biosynthesis of astaxanthin. 2011 Microb. Cell Fact. pmid:21521516
Zhou K et al. Novel reference genes for quantifying transcriptional responses of Escherichia coli to protein overexpression by quantitative PCR. 2011 BMC Mol. Biol. pmid:21513543