| MeSH term | MeSH ID | Detail |
|---|---|---|
| Melanoma | D008545 | 69 associated lipids |
Total
1
Dimethylallyl pyrophosphate
Dimethylallyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Dimethylallyl pyrophosphate is associated with abnormalities such as Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as Anabolism, Biochemical Pathway, Oxidation, Process and Chelating Activity [MoA]. Dimethylallyl pyrophosphate often locates in Chloroplasts, Plastids, chloroplast stroma, Cytosol and Cell membrane. The associated genes with Dimethylallyl pyrophosphate are IRF6 wt Allele and ADRBK1 gene. The related lipids are Sterols.
Cross Reference
Introduction
To understand associated biological information of Dimethylallyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Dimethylallyl pyrophosphate?
Dimethylallyl pyrophosphate is suspected in and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Dimethylallyl pyrophosphate
PubChem Associated disorders and diseases
What pathways are associated with Dimethylallyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Dimethylallyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
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| Pathway name | Related literatures |
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Dimethylallyl pyrophosphate?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Dimethylallyl pyrophosphate?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with Dimethylallyl pyrophosphate?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with Dimethylallyl pyrophosphate?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with Dimethylallyl pyrophosphate?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Dimethylallyl pyrophosphate
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|---|---|---|---|---|
| Bohlmann J and Gershenzon J | Old substrates for new enzymes of terpenoid biosynthesis. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19553206 |
| Gräwert T et al. | Structure of active IspH enzyme from Escherichia coli provides mechanistic insights into substrate reduction. | 2009 | Angew. Chem. Int. Ed. Engl. | pmid:19569147 |
| Jauhiainen M et al. | Analysis of endogenous ATP analogs and mevalonate pathway metabolites in cancer cell cultures using liquid chromatography-electrospray ionization mass spectrometry. | 2009 | J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. | pmid:19665949 |
| Majumdar A et al. | Probing phosphorylation by non-mammalian isoprenoid biosynthetic enzymes using (1)H-(31)P-(31)P correlation NMR spectroscopy. | 2009 | Mol Biosyst | pmid:19668858 |
| Gilg AB et al. | Unique animal prenyltransferase with monoterpene synthase activity. | 2009 | Naturwissenschaften | pmid:19277597 |
| Nieuwenhuizen NJ et al. | Two terpene synthases are responsible for the major sesquiterpenes emitted from the flowers of kiwifruit (Actinidia deliciosa). | 2009 | J. Exp. Bot. | pmid:19516075 |
| Iriti M and Faoro F | Chemical diversity and defence metabolism: how plants cope with pathogens and ozone pollution. | 2009 | Int J Mol Sci | pmid:20111684 |
| Ganjewala D et al. | An account of cloned genes of Methyl-erythritol-4-phosphate pathway of isoprenoid biosynthesis in plants. | 2009 | Curr Issues Mol Biol | pmid:19193963 |
| Suzuki M et al. | Complete blockage of the mevalonate pathway results in male gametophyte lethality. | 2009 | J. Exp. Bot. | pmid:19363204 |
| Sillero MA et al. | Synthesis of ATP derivatives of compounds of the mevalonate pathway (isopentenyl di- and triphosphate; geranyl di- and triphosphate, farnesyl di- and triphosphate, and dimethylallyl diphosphate) catalyzed by T4 RNA ligase, T4 DNA ligase and other ligases Potential relationship with the effect of bisphosphonates on osteoclasts. | 2009 | Biochem. Pharmacol. | pmid:19414000 |
| Tsuruta H et al. | High-level production of amorpha-4,11-diene, a precursor of the antimalarial agent artemisinin, in Escherichia coli. | 2009 | PLoS ONE | pmid:19221601 |
| Lücker J et al. | Generation of a predicted protein database from EST data and application to iTRAQ analyses in grape (Vitis vinifera cv. Cabernet Sauvignon) berries at ripening initiation. | 2009 | BMC Genomics | pmid:19171055 |
| Saikia S and Scott B | Functional analysis and subcellular localization of two geranylgeranyl diphosphate synthases from Penicillium paxilli. | 2009 | Mol. Genet. Genomics | pmid:19529962 |
| Vandermoten S et al. | New insights into short-chain prenyltransferases: structural features, evolutionary history and potential for selective inhibition. | 2009 | Cell. Mol. Life Sci. | pmid:19633972 |
| Mann FM et al. | Edaxadiene: a new bioactive diterpene from Mycobacterium tuberculosis. | 2009 | J. Am. Chem. Soc. | pmid:19583202 |
| Rubio-Aliaga I et al. | Dll1 haploinsufficiency in adult mice leads to a complex phenotype affecting metabolic and immunological processes. | 2009 | PLoS ONE | pmid:19562077 |
| Correia DV et al. | Highly active microbial phosphoantigen induces rapid yet sustained MEK/Erk- and PI-3K/Akt-mediated signal transduction in anti-tumor human gammadelta T-cells. | 2009 | PLoS ONE | pmid:19479075 |
| Vinella D et al. | Iron-sulfur (Fe/S) protein biogenesis: phylogenomic and genetic studies of A-type carriers. | 2009 | PLoS Genet. | pmid:19478995 |
| Wiberley AE et al. | Regulation of isoprene emission from poplar leaves throughout a day. | 2009 | Plant Cell Environ. | pmid:19389050 |
| Saleh O et al. | Aromatic prenylation in phenazine biosynthesis: dihydrophenazine-1-carboxylate dimethylallyltransferase from Streptomyces anulatus. | 2009 | J. Biol. Chem. | pmid:19339241 |
| Ramsden NL et al. | A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy. | 2009 | J. Med. Chem. | pmid:19320487 |
| Eberl M et al. | A rapid crosstalk of human gammadelta T cells and monocytes drives the acute inflammation in bacterial infections. | 2009 | PLoS Pathog. | pmid:19229322 |
| Green S et al. | Defining the potassium binding region in an apple terpene synthase. | 2009 | J. Biol. Chem. | pmid:19181671 |
| Marks MD et al. | Identification of candidate genes affecting Delta9-tetrahydrocannabinol biosynthesis in Cannabis sativa. | 2009 | J. Exp. Bot. | pmid:19581347 |
| Whitaker JW et al. | The transferome of metabolic genes explored: analysis of the horizontal transfer of enzyme encoding genes in unicellular eukaryotes. | 2009 | Genome Biol. | pmid:19368726 |
| Xie W et al. | Initiation of rubber biosynthesis: In vitro comparisons of benzophenone-modified diphosphate analogues in three rubber-producing species. | 2008 | Phytochemistry | pmid:18799172 |
| Rekittke I et al. | Structure of (E)-4-hydroxy-3-methyl-but-2-enyl diphosphate reductase, the terminal enzyme of the non-mevalonate pathway. | 2008 | J. Am. Chem. Soc. | pmid:19035630 |
| Ro DK et al. | Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid. | 2008 | BMC Biotechnol. | pmid:18983675 |
| Fujiwara S et al. | Efficient synthesis of trans-polyisoprene compounds using two thermostable enzymes in an organic-aqueous dual-liquid phase system. | 2008 | Biochem. Biophys. Res. Commun. | pmid:17976371 |
| Wiberley AE et al. | Regulation of isoprene emission in Populus trichocarpa leaves subjected to changing growth temperature. | 2008 | Plant Cell Environ. | pmid:17996012 |
| Okada K et al. | Genetic evidence for the role of isopentenyl diphosphate isomerases in the mevalonate pathway and plant development in Arabidopsis. | 2008 | Plant Cell Physiol. | pmid:18303110 |
| Köllner TG et al. | Protonation of a neutral (S)-beta-bisabolene intermediate is involved in (S)-beta-macrocarpene formation by the maize sesquiterpene synthases TPS6 and TPS11. | 2008 | J. Biol. Chem. | pmid:18524777 |
| Kuo CJ et al. | Structure-based inhibitors exhibit differential activities against Helicobacter pylori and Escherichia coli undecaprenyl pyrophosphate synthases. | 2008 | J. Biomed. Biotechnol. | pmid:18382620 |
| Galichet A et al. | Farnesylation directs AtIPT3 subcellular localization and modulates cytokinin biosynthesis in Arabidopsis. | 2008 | Plant Physiol. | pmid:18184738 |
| Mondego JM et al. | A genome survey of Moniliophthora perniciosa gives new insights into Witches' Broom Disease of cacao. | 2008 | BMC Genomics | pmid:19019209 |
| Argout X et al. | Towards the understanding of the cocoa transcriptome: Production and analysis of an exhaustive dataset of ESTs of Theobroma cacao L. generated from various tissues and under various conditions. | 2008 | BMC Genomics | pmid:18973681 |
| Hirano K et al. | Comprehensive transcriptome analysis of phytohormone biosynthesis and signaling genes in microspore/pollen and tapetum of rice. | 2008 | Plant Cell Physiol. | pmid:18718932 |
| Docampo R and Moreno SN | The acidocalcisome as a target for chemotherapeutic agents in protozoan parasites. | 2008 | Curr. Pharm. Des. | pmid:18473837 |
| Vandermoten S et al. | Characterization of a novel aphid prenyltransferase displaying dual geranyl/farnesyl diphosphate synthase activity. | 2008 | FEBS Lett. | pmid:18466770 |
| Phillips MA et al. | The Arabidopsis thaliana type I Isopentenyl Diphosphate Isomerases are targeted to multiple subcellular compartments and have overlapping functions in isoprenoid biosynthesis. | 2008 | Plant Cell | pmid:18319397 |
| Thibodeaux CJ et al. | Evidence for the involvement of acid/base chemistry in the reaction catalyzed by the type II isopentenyl diphosphate/dimethylallyl diphosphate isomerase from Staphylococcus aureus. | 2008 | Biochemistry | pmid:18229948 |
| Jassbi AR et al. | Silencing geranylgeranyl diphosphate synthase in Nicotiana attenuata dramatically impairs resistance to tobacco hornworm. | 2008 | Plant Physiol. | pmid:17965175 |
| Dupont FM | Metabolic pathways of the wheat (Triticum aestivum) endosperm amyloplast revealed by proteomics. | 2008 | BMC Plant Biol. | pmid:18419817 |
| Ducreux LJ et al. | Expression profiling of potato germplasm differentiated in quality traits leads to the identification of candidate flavour and texture genes. | 2008 | J. Exp. Bot. | pmid:18987392 |
| Sasaki K et al. | Cloning and characterization of naringenin 8-prenyltransferase, a flavonoid-specific prenyltransferase of Sophora flavescens. | 2008 | Plant Physiol. | pmid:18218974 |
| Schmidt A and Gershenzon J | Cloning and characterization of two different types of geranyl diphosphate synthases from Norway spruce (Picea abies). | 2008 | Phytochemistry | pmid:17673268 |
| Crowhurst RN et al. | Analysis of expressed sequence tags from Actinidia: applications of a cross species EST database for gene discovery in the areas of flavor, health, color and ripening. | 2008 | BMC Genomics | pmid:18655731 |
| AlcaÃno J et al. | Cloning of the cytochrome p450 reductase (crtR) gene and its involvement in the astaxanthin biosynthesis of Xanthophyllomyces dendrorhous. | 2008 | BMC Microbiol. | pmid:18837978 |
| Arimura G et al. | Herbivore-induced terpenoid emission in Medicago truncatula: concerted action of jasmonate, ethylene and calcium signaling. | 2008 | Planta | pmid:17924138 |
| de Ruyck J and Wouters J | Structure-based drug design targeting biosynthesis of isoprenoids: a crystallographic state of the art of the involved enzymes. | 2008 | Curr. Protein Pept. Sci. | pmid:18393884 |
| Yoon SH et al. | Increased beta-carotene production in recombinant Escherichia coli harboring an engineered isoprenoid precursor pathway with mevalonate addition. | 2007 May-Jun | Biotechnol. Prog. | pmid:17500531 |
| Moe M et al. | Gene expression profiles in testis of pigs with extreme high and low levels of androstenone. | 2007 | BMC Genomics | pmid:17988377 |
| Yoon SH et al. | Engineering the lycopene synthetic pathway in E. coli by comparison of the carotenoid genes of Pantoea agglomerans and Pantoea ananatis. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17115209 |
| Phillips MA et al. | Functional identification and differential expression of 1-deoxy-D-xylulose 5-phosphate synthase in induced terpenoid resin formation of Norway spruce (Picea abies). | 2007 | Plant Mol. Biol. | pmid:17687625 |
| Das A et al. | An update on microbial carotenoid production: application of recent metabolic engineering tools. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17912511 |
| Johnston JB et al. | Type-2 isopentenyl diphosphate isomerase. Mechanistic studies with cyclopropyl and epoxy analogues. | 2007 | J. Am. Chem. Soc. | pmid:17547410 |
| Yin WB et al. | CdpNPT, an N-prenyltransferase from Aspergillus fumigatus: overproduction, purification and biochemical characterisation. | 2007 | Chembiochem | pmid:17525915 |
| Walsh CT | Revealing coupling patterns in isoprenoid alkylation biocatalysis. | 2007 | ACS Chem. Biol. | pmid:17518430 |
| Behnke K et al. | Transgenic, non-isoprene emitting poplars don't like it hot. | 2007 | Plant J. | pmid:17587235 |
| Amslinger S et al. | Stimulation of Vgamma9/Vdelta2 T-lymphocyte proliferation by the isoprenoid precursor, (E)-1-hydroxy-2-methyl-but-2-enyl 4-diphosphate. | 2007 | Immunobiology | pmid:17270709 |
| Christianson DW | Chemistry. Roots of biosynthetic diversity. | 2007 | Science | pmid:17412944 |
| Green S et al. | Unusual features of a recombinant apple alpha-farnesene synthase. | 2007 | Phytochemistry | pmid:17140613 |
| Matsumura Y et al. | The carboxyl-terminal region of the geranylgeranyl diphosphate synthase is indispensable for the stabilization of the region involved in substrate binding and catalysis. | 2007 | J. Biochem. | pmid:17846065 |
| Withers ST and Keasling JD | Biosynthesis and engineering of isoprenoid small molecules. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17115212 |
| Kremer A et al. | A 7-dimethylallyltryptophan synthase from Aspergillus fumigatus: overproduction, purification and biochemical characterization. | 2007 | Microbiology (Reading, Engl.) | pmid:17906140 |
| Omoigui S | The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases. | 2007 | Immun Ageing | pmid:17374166 |
| Sgraja T et al. | Structure, substrate recognition and reactivity of Leishmania major mevalonate kinase. | 2007 | BMC Struct. Biol. | pmid:17397541 |
| Rothman SC et al. | Kinetic and spectroscopic characterization of type II isopentenyl diphosphate isomerase from Thermus thermophilus: evidence for formation of substrate-induced flavin species. | 2007 | Biochemistry | pmid:17428035 |
| Julsing MK et al. | Functional analysis of genes involved in the biosynthesis of isoprene in Bacillus subtilis. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17458547 |
| Glickman JF and Schmid A | Farnesyl pyrophosphate synthase: real-time kinetics and inhibition by nitrogen-containing bisphosphonates in a scintillation assay. | 2007 | Assay Drug Dev Technol | pmid:17477829 |
| Saito K et al. | Short-chain prenyl diphosphate synthase that condenses isopentenyl diphosphate with dimethylallyl diphosphate in ispA null Escherichia coli strain lacking farnesyl diphosphate synthase. | 2007 | J. Biosci. Bioeng. | pmid:17630132 |
| Grimplet J et al. | Tissue-specific mRNA expression profiling in grape berry tissues. | 2007 | BMC Genomics | pmid:17584945 |
| Velasco R et al. | A high quality draft consensus sequence of the genome of a heterozygous grapevine variety. | 2007 | PLoS ONE | pmid:18094749 |
| Buetow L et al. | The structure of Mycobacteria 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase, an essential enzyme, provides a platform for drug discovery. | 2007 | BMC Struct. Biol. | pmid:17956607 |
| Kittleman W et al. | Characterization and mechanistic studies of type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase from Staphylococcus aureus. | 2007 | Biochemistry | pmid:17585782 |
| Cassera MB et al. | Effect of fosmidomycin on metabolic and transcript profiles of the methylerythritol phosphate pathway in Plasmodium falciparum. | 2007 | Mem. Inst. Oswaldo Cruz | pmid:17568945 |
| Loivamäki M et al. | Arabidopsis, a model to study biological functions of isoprene emission? | 2007 | Plant Physiol. | pmid:17468218 |
| Perrin RM et al. | Transcriptional regulation of chemical diversity in Aspergillus fumigatus by LaeA. | 2007 | PLoS Pathog. | pmid:17432932 |
| Xie W et al. | Structure of tRNA dimethylallyltransferase: RNA modification through a channel. | 2007 | J. Mol. Biol. | pmid:17292915 |
| Scott E et al. | Biomass in the manufacture of industrial products--the use of proteins and amino acids. | 2007 | Appl. Microbiol. Biotechnol. | pmid:17387469 |
| Manzano D et al. | Overexpression of farnesyl diphosphate synthase in Arabidopsis mitochondria triggers light-dependent lesion formation and alters cytokinin homeostasis. | 2006 | Plant Mol. Biol. | pmid:16786301 |
| Thulasiram HV et al. | Synthesis of deuterium-labeled derivatives of dimethylallyl diphosphate. | 2006 | J. Org. Chem. | pmid:16468838 |
| Sen SE et al. | Juvenile hormone biosynthesis in M. sexta: substrate specificity of insect prenyltransferase utilizing homologous diphosphate analogs. | 2006 | Insect Biochem. Mol. Biol. | pmid:17046596 |
| Kloer DP et al. | Structure and reaction geometry of geranylgeranyl diphosphate synthase from Sinapis alba. | 2006 | Biochemistry | pmid:17176041 |
| Nogués I et al. | Dimethylallyl diphosphate and geranyl diphosphate pools of plant species characterized by different isoprenoid emissions. | 2006 | Plant Physiol. | pmid:16461390 |
| Thulasiram HV and Poulter CD | Farnesyl diphosphate synthase: the art of compromise between substrate selectivity and stereoselectivity. | 2006 | J. Am. Chem. Soc. | pmid:17147392 |
| Benetka W et al. | Farnesylation or geranylgeranylation? Efficient assays for testing protein prenylation in vitro and in vivo. | 2006 | BMC Biochem. | pmid:16507103 |
| Muñoz-Bertomeu J et al. | Up-regulation of 1-deoxy-D-xylulose-5-phosphate synthase enhances production of essential oils in transgenic spike lavender. | 2006 | Plant Physiol. | pmid:16980564 |
| Brück TB and Kerr RG | Purification and kinetic properties of elisabethatriene synthase from the coral Pseudopterogorgia elisabethae. | 2006 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:16423548 |
| Cervantes-Cervantes M et al. | Maize cDNAs expressed in endosperm encode functional farnesyl diphosphate synthase with geranylgeranyl diphosphate synthase activity. | 2006 | Plant Physiol. | pmid:16581875 |
| Yoon SH et al. | Enhanced lycopene production in Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate. | 2006 | Biotechnol. Bioeng. | pmid:16547999 |
| Hsiao YY et al. | Comparison of transcripts in Phalaenopsis bellina and Phalaenopsis equestris (Orchidaceae) flowers to deduce monoterpene biosynthesis pathway. | 2006 | BMC Plant Biol. | pmid:16836766 |
| Song L | A soluble form of phosphatase in Saccharomyces cerevisiae capable of converting farnesyl diphosphate into E,E-farnesol. | 2006 | Appl. Biochem. Biotechnol. | pmid:16484724 |
| Guo RT et al. | Crystal structures of undecaprenyl pyrophosphate synthase in complex with magnesium, isopentenyl pyrophosphate, and farnesyl thiopyrophosphate: roles of the metal ion and conserved residues in catalysis. | 2005 | J. Biol. Chem. | pmid:15788389 |
| Wu Z et al. | Isopentenyl diphosphate isomerase. Mechanism-based inhibition by diene analogues of isopentenyl diphosphate and dimethylallyl diphosphate. | 2005 | J. Am. Chem. Soc. | pmid:16332094 |
| Ku B et al. | Preparation, characterization, and optimization of an in vitro C30 carotenoid pathway. | 2005 | Appl. Environ. Microbiol. | pmid:16269684 |
| Margl L et al. | Biosynthesis of benzofuran derivatives in root cultures of Tagetes patula via phenylalanine and 1-deoxy-D-xylulose 5-phosphate. | 2005 | Phytochemistry | pmid:15845407 |
| Sabehi G et al. | New insights into metabolic properties of marine bacteria encoding proteorhodopsins. | 2005 | PLoS Biol. | pmid:16008504 |
| Fujisaki S et al. | Disruption of the structural gene for farnesyl diphosphate synthase in Escherichia coli. | 2005 | J. Biochem. | pmid:15809342 |
| Mayrhofer S et al. | Diurnal and seasonal variation of isoprene biosynthesis-related genes in grey poplar leaves. | 2005 | Plant Physiol. | pmid:16126852 |