|MeSH term||MeSH ID||Detail|
|Melanoma||D008545||69 associated lipids|
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
|Disease||Cross reference||Weighted score||Related literature|
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
|Pathway name||Related literatures|
Associated locations are in red color. Not associated locations are in black.
|Function||Cross reference||Weighted score||Related literatures|
There are no associated biomedical information in the current reference collection.
|Henry LK et al.||Orthologs of the archaeal isopentenyl phosphate kinase regulate terpenoid production in plants.||2015||Proc. Natl. Acad. Sci. U.S.A.||pmid:26216978|
|Garg A et al.||Targeting protein translation, RNA splicing, and degradation by morpholino-based conjugates in Plasmodium falciparum.||2015||Proc. Natl. Acad. Sci. U.S.A.||pmid:26351679|
|Legut M et al.||The promise of Î³Î´ T cells and the Î³Î´ T cell receptor for cancer immunotherapy.||2015||Cell. Mol. Immunol.||pmid:25864915|
|Rhodes DA et al.||Activation of human Î³Î´ T cells by cytosolic interactions of BTN3A1 with soluble phosphoantigens and the cytoskeletal adaptor periplakin.||2015||J. Immunol.||pmid:25637025|
|Nisar N et al.||Carotenoid metabolism in plants.||2015||Mol Plant||pmid:25578273|
|Pertusi DA et al.||Efficient searching and annotation of metabolic networks using chemical similarity.||2015||Bioinformatics||pmid:25417203|
|Wiley JD et al.||Isoprenoid precursor biosynthesis is the essential metabolic role of the apicoplast during gametocytogenesis in Plasmodium falciparum.||2015||Eukaryotic Cell||pmid:25446055|
|Bowman JD et al.||Antiapicoplast and gametocytocidal screening to identify the mechanisms of action of compounds within the malaria box.||2014||Antimicrob. Agents Chemother.||pmid:24247137|
|Mannen K et al.||Coordinated transcriptional regulation of isopentenyl diphosphate biosynthetic pathway enzymes in plastids by phytochrome-interacting factor 5.||2014||Biochem. Biophys. Res. Commun.||pmid:24342623|
|Bentinger M et al.||Effects of various squalene epoxides on coenzyme Q and cholesterol synthesis.||2014||Biochim. Biophys. Acta||pmid:24747199|