|MeSH term||MeSH ID||Detail|
|Melanoma||D008545||69 associated lipids|
Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.
To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.
|Disease||Cross reference||Weighted score||Related literature|
We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.
|Pathway name||Related literatures|
Associated locations are in red color. Not associated locations are in black.
|Location||Cross reference||Weighted score||Related literatures|
|Function||Cross reference||Weighted score||Related literatures|
|Lipid concept||Cross reference||Weighted score||Related literatures|
|Gene||Cross reference||Weighted score||Related literatures|
There are no associated biomedical information in the current reference collection.
|Wang H et al.||Butyrophilin 3A1 plays an essential role in prenyl pyrophosphate stimulation of human VÎ³2VÎ´2 T cells.||2013||J. Immunol.||pmid:23833237|
|Vavassori S et al.||Butyrophilin 3A1 binds phosphorylated antigens and stimulates human Î³Î´ T cells.||2013||Nat. Immunol.||pmid:23872678|
|Bessoff K et al.||Drug repurposing screen reveals FDA-approved inhibitors of human HMG-CoA reductase and isoprenoid synthesis that block Cryptosporidium parvum growth.||2013||Antimicrob. Agents Chemother.||pmid:23380723|
|Idrees AS et al.||Comparison of Î³Î´ T cell responses and farnesyl diphosphate synthase inhibition in tumor cells pretreated with zoledronic acid.||2013||Cancer Sci.||pmid:23387443|
|Banerjee A et al.||Feedback inhibition of deoxy-D-xylulose-5-phosphate synthase regulates the methylerythritol 4-phosphate pathway.||2013||J. Biol. Chem.||pmid:23612965|
|Zhao L et al.||Methylerythritol phosphate pathway of isoprenoid biosynthesis.||2013||Annu. Rev. Biochem.||pmid:23746261|
|Leblond JD et al.||Sterol composition and biosynthetic genes of the recently discovered photosynthetic alveolate, Chromera velia (chromerida), a close relative of apicomplexans.||2012 May-Jun||J. Eukaryot. Microbiol.||pmid:22313428|
|Modi ND and Lentzsch S||Bisphosphonates as antimyeloma drugs.||2012||Leukemia||pmid:22005788|
|Soriano-Sarabia N et al.||Primary MHC-class II(+) cells are necessary to promote resting VÎ´2 cell expansion in response to (E)-4-hydroxy-3-methyl-but-2-enyl-pyrophosphate and isopentenyl pyrophosphate.||2012||J. Immunol.||pmid:23105138|
|Song AA et al.||Functional expression of an orchid fragrance gene in Lactococcus lactis.||2012||Int J Mol Sci||pmid:22408409|