Isopentenyl pyrophosphate

Isopentenyl pyrophosphate is a lipid of Prenol Lipids (PR) class. Isopentenyl pyrophosphate is associated with abnormalities such as Tuberculosis, NAVAJO NEUROHEPATOPATHY and Cryptosporidiosis. The involved functions are known as Signal, Anabolism, T-Cell Activation, T-Cell Proliferation and isoprenoid biosynthetic process. Isopentenyl pyrophosphate often locates in Protoplasm, Host Cell, soluble, Plastids and Cell surface. The associated genes with Isopentenyl pyrophosphate are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, HLA-E gene, RAP1A gene, Gene Family and Orthologous Gene. The related lipids are Steroids, Sterols and isopentenol.

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Introduction

To understand associated biological information of Isopentenyl pyrophosphate, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Isopentenyl pyrophosphate?

Isopentenyl pyrophosphate is suspected in Tuberculosis, NAVAJO NEUROHEPATOPATHY, Cryptosporidiosis and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Isopentenyl pyrophosphate

MeSH term MeSH ID Detail
Melanoma D008545 69 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Isopentenyl pyrophosphate

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Isopentenyl pyrophosphate through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

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What functions are associated with Isopentenyl pyrophosphate?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Isopentenyl pyrophosphate?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Isopentenyl pyrophosphate?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Isopentenyl pyrophosphate

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Authors Title Published Journal PubMed Link
Barrero RA et al. De novo assembly of Euphorbia fischeriana root transcriptome identifies prostratin pathway related genes. 2011 BMC Genomics pmid:22151917
Morrone D et al. Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering. 2010 Appl. Microbiol. Biotechnol. pmid:19777230
Urzúa U et al. Tumor and reproductive traits are linked by RNA metabolism genes in the mouse ovary: a transcriptome-phenotype association analysis. 2010 BMC Genomics pmid:21210965
Piepho M et al. Simultaneous effects of light intensity and phosphorus supply on the sterol content of phytoplankton. 2010 PLoS ONE pmid:21209879
Mongan MA et al. A novel statistical algorithm for gene expression analysis helps differentiate pregnane X receptor-dependent and independent mechanisms of toxicity. 2010 PLoS ONE pmid:21203578
Holen I and Coleman RE Anti-tumour activity of bisphosphonates in preclinical models of breast cancer. 2010 Breast Cancer Res. pmid:21176176
Kim J et al. Three serendipitous pathways in E. coli can bypass a block in pyridoxal-5'-phosphate synthesis. 2010 Mol. Syst. Biol. pmid:21119630
Wang C et al. Farnesol production from Escherichia coli by harnessing the exogenous mevalonate pathway. 2010 Biotechnol. Bioeng. pmid:20552672
Sharma NK et al. Type II isopentenyl diphosphate isomerase: probing the mechanism with alkyne/allene diphosphate substrate analogues. 2010 Biochemistry pmid:20560533
Leonard E et al. Combining metabolic and protein engineering of a terpenoid biosynthetic pathway for overproduction and selectivity control. 2010 Proc. Natl. Acad. Sci. U.S.A. pmid:20643967
Pazianas M et al. Long-term treatment with bisphosphonates and their safety in postmenopausal osteoporosis. 2010 Ther Clin Risk Manag pmid:20668715
Zhang F et al. An L1 box binding protein, GbML1, interacts with GbMYB25 to control cotton fibre development. 2010 J. Exp. Bot. pmid:20667961
Maniar A et al. Human gammadelta T lymphocytes induce robust NK cell-mediated antitumor cytotoxicity through CD137 engagement. 2010 Blood pmid:20519625
Mookerjee-Basu J et al. F1-adenosine triphosphatase displays properties characteristic of an antigen presentation molecule for Vgamma9Vdelta2 T cells. 2010 J. Immunol. pmid:20483757
Yao S et al. Differentiation, distribution and gammadelta T cell-driven regulation of IL-22-producing T cells in tuberculosis. 2010 PLoS Pathog. pmid:20195465
Schmidt T et al. Characterization of rubber particles and rubber chain elongation in Taraxacum koksaghyz. 2010 BMC Biochem. pmid:20170509
Monnet C et al. The arthrobacter arilaitensis Re117 genome sequence reveals its genetic adaptation to the surface of cheese. 2010 PLoS ONE pmid:21124797
Rios-Estepa R et al. Mathematical modeling-guided evaluation of biochemical, developmental, environmental, and genotypic determinants of essential oil composition and yield in peppermint leaves. 2010 Plant Physiol. pmid:20147490
Cavalier-Smith T Origin of the cell nucleus, mitosis and sex: roles of intracellular coevolution. 2010 Biol. Direct pmid:20132544
Lambert C et al. The first bite--profiling the predatosome in the bacterial pathogen Bdellovibrio. 2010 PLoS ONE pmid:20062540
Trost E et al. Complete genome sequence and lifestyle of black-pigmented Corynebacterium aurimucosum ATCC 700975 (formerly C. nigricans CN-1) isolated from a vaginal swab of a woman with spontaneous abortion. 2010 BMC Genomics pmid:20137072
Lim L and McFadden GI The evolution, metabolism and functions of the apicoplast. 2010 Philos. Trans. R. Soc. Lond., B, Biol. Sci. pmid:20124342
Takaichi S et al. Carotenoids of Gemmatimonas aurantiaca (Gemmatimonadetes): identification of a novel carotenoid, deoxyoscillol 2-rhamnoside, and proposed biosynthetic pathway of oscillol 2,2'-dirhamnoside. 2010 Microbiology (Reading, Engl.) pmid:19959572
Behnke K et al. RNAi-mediated suppression of isoprene emission in poplar transiently impacts phenolic metabolism under high temperature and high light intensities: a transcriptomic and metabolomic analysis. 2010 Plant Mol. Biol. pmid:20526857
Tchaparian E et al. Identification of transcriptional networks responding to pyrroloquinoline quinone dietary supplementation and their influence on thioredoxin expression, and the JAK/STAT and MAPK pathways. 2010 Biochem. J. pmid:20491655
Dolzhenko Y et al. UV-B modulates the interplay between terpenoids and flavonoids in peppermint (Mentha x piperita L.). 2010 J. Photochem. Photobiol. B, Biol. pmid:20627615
Gresh N et al. Analysis of the interactions taking place in the recognition site of a bimetallic Mg(II)-Zn(II) enzyme, isopentenyl diphosphate isomerase. a parallel quantum-chemical and polarizable molecular mechanics study. 2010 J Phys Chem B pmid:20329783
Dellas N and Noel JP Mutation of archaeal isopentenyl phosphate kinase highlights mechanism and guides phosphorylation of additional isoprenoid monophosphates. 2010 ACS Chem. Biol. pmid:20392112
Chen M and Poulter CD Characterization of thermophilic archaeal isopentenyl phosphate kinases. 2010 Biochemistry pmid:19928876
Räikkönen J et al. Mevalonate pathway intermediates downregulate zoledronic acid-induced isopentenyl pyrophosphate and ATP analog formation in human breast cancer cells. 2010 Biochem. Pharmacol. pmid:19819230
Mitrofan LM et al. Lysosomal-mitochondrial axis in zoledronic acid-induced apoptosis in human follicular lymphoma cells. 2010 J. Biol. Chem. pmid:19875454
Hasunuma T et al. Metabolic engineering by plastid transformation as a strategy to modulate isoprenoid yield in plants. 2010 Methods Mol. Biol. pmid:20552454
Huang CH et al. Binding of nitrogen-containing bisphosphonates (N-BPs) to the Trypanosoma cruzi farnesyl diphosphate synthase homodimer. 2010 Proteins pmid:19876942
Meraviglia S et al. In vivo manipulation of Vgamma9Vdelta2 T cells with zoledronate and low-dose interleukin-2 for immunotherapy of advanced breast cancer patients. 2010 Clin. Exp. Immunol. pmid:20491785
Yadav VR et al. Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer. 2010 Toxins (Basel) pmid:22069560
Cabillic F et al. Aminobisphosphonate-pretreated dendritic cells trigger successful Vgamma9Vdelta2 T cell amplification for immunotherapy in advanced cancer patients. 2010 Cancer Immunol. Immunother. pmid:20582413
Ganjewala D and Luthra R Essential oil biosynthesis and regulation in the genus Cymbopogon. 2010 Nat Prod Commun pmid:20184044
Rojruthai P et al. In vitro synthesis of high molecular weight rubber by Hevea small rubber particles. 2010 J. Biosci. Bioeng. pmid:20129092
Chang TH et al. Structure of a heterotetrameric geranyl pyrophosphate synthase from mint (Mentha piperita) reveals intersubunit regulation. 2010 Plant Cell pmid:20139160
Goto T et al. Various Terpenoids Derived from Herbal and Dietary Plants Function as PPAR Modulators and Regulate Carbohydrate and Lipid Metabolism. 2010 PPAR Res pmid:20613991
Diamond DL et al. Temporal proteome and lipidome profiles reveal hepatitis C virus-associated reprogramming of hepatocellular metabolism and bioenergetics. 2010 PLoS Pathog. pmid:20062526
Nickerson ML et al. UBIAD1 mutation alters a mitochondrial prenyltransferase to cause Schnyder corneal dystrophy. 2010 PLoS ONE pmid:20505825
Singkaravanit S et al. Geranylgeranyl diphosphate synthase genes in entomopathogenic fungi. 2010 Appl. Microbiol. Biotechnol. pmid:19690851
Kishi-Kaboshi M et al. A rice fungal MAMP-responsive MAPK cascade regulates metabolic flow to antimicrobial metabolite synthesis. 2010 Plant J. pmid:20525005
Costa GG et al. Transcriptome analysis of the oil-rich seed of the bioenergy crop Jatropha curcas L. 2010 BMC Genomics pmid:20691070
Thibodeaux CJ et al. Linear free energy relationships demonstrate a catalytic role for the flavin mononucleotide coenzyme of the type II isopentenyl diphosphate:dimethylallyl diphosphate isomerase. 2010 J. Am. Chem. Soc. pmid:20593767
Narayanasamy P et al. Synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate and kinetic studies of Mycobacterium tuberculosis IspF. 2010 Chem. Biol. pmid:20189102
Ibrahim MA et al. Elevation of night-time temperature increases terpenoid emissions from Betula pendula and Populus tremula. 2010 J. Exp. Bot. pmid:20181662
Dellomonaco C et al. The path to next generation biofuels: successes and challenges in the era of synthetic biology. 2010 Microb. Cell Fact. pmid:20089184
Hawari AH and Mohamed-Hussein ZA Simulation of a Petri net-based model of the terpenoid biosynthesis pathway. 2010 BMC Bioinformatics pmid:20144236