(-)-Menthol

(-)-menthol is a lipid of Prenol Lipids (PR) class. (-)-menthol is associated with abnormalities such as Wiskott-Aldrich Syndrome. The involved functions are known as Agent, Anabolism, Signal Transduction, Binding (Molecular Function) and Signal Transduction Pathways. (-)-menthol often locates in Membrane, Tissue fiber and Dominant hand. The associated genes with (-)-Menthol are REG1A gene, UGT2B7 gene, HM13 gene and SCN10A gene. The related lipids are Steroids and androsterone glucuronide.

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Introduction

To understand associated biological information of (-)-Menthol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with (-)-Menthol?

(-)-Menthol is suspected in and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with (-)-Menthol

MeSH term MeSH ID Detail
Pain D010146 64 associated lipids
Endophthalmitis D009877 12 associated lipids
Uveitis, Posterior D015866 5 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with (-)-Menthol

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with (-)-Menthol?

Related references are published most in these journals:

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What functions are associated with (-)-Menthol?


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Function Cross reference Weighted score Related literatures

What lipids are associated with (-)-Menthol?

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What genes are associated with (-)-Menthol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with (-)-Menthol?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with (-)-Menthol

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Authors Title Published Journal PubMed Link
Liu SC et al. The identification of the TRPM8 channel on primary culture of human nasal epithelial cells and its response to cooling. 2017 Medicine (Baltimore) pmid:28767579
Marumoto S et al. Biotransformation of (-)-(1R,4S)-Menthone and (+)-(1S,4R)-Menthone by the Common Cutworm Spodoptera litura Larvae. 2017 J Oleo Sci pmid:28701651
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Lai PM et al. Efficacy and safety of topical diclofenac/menthol gel for ankle sprain: A randomized, double-blind, placebo- and active-controlled trial. 2017 J. Int. Med. Res. pmid:28345425
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Suchodolski J et al. Antifungal activity of ionic liquids based on (-)-menthol: a mechanism study. 2017 Microbiol. Res. pmid:28219526
Chopyk J et al. Mentholation affects the cigarette microbiota by selecting for bacteria resistant to harsh environmental conditions and selecting against potential bacterial pathogens. 2017 Microbiome pmid:28202080
Van Landingham C et al. Stroke risk among menthol versus non-menthol cigarette smokers in the United States: Analysis of the National Health and Nutrition Examination Survey (NHANES). 2017 Regul. Toxicol. Pharmacol. pmid:28163170
Yoshida S et al. Molecular Interaction between Intercellular Lipids in the Stratum Corneum and l-Menthol, as Analyzed by Synchrotron X-Ray Diffraction. 2017 Chem. Pharm. Bull. pmid:28154307
Huang W et al. Quantitative analysis of menthol in human urine using solid phase microextraction and stable isotope dilution gas chromatography-mass spectrometry. 2017 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:28153673
Craighead DH et al. Mechanisms and time course of menthol-induced cutaneous vasodilation. 2017 Microvasc. Res. pmid:27899298
Sharifzadeh A et al. Synergistic anticandidal activity of menthol in combination with itraconazole and nystatin against clinical Candida glabrata and Candida krusei isolates. 2017 Microb. Pathog. pmid:28431915
Prins TJ et al. A Survey of Practice and Knowledge of Refugee and Migrant Pregnant Mothers Surrounding Neonatal Jaundice on the Thailand-Myanmar Border. 2017 J. Trop. Pediatr. pmid:27576869
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Aperce CC et al. Effects of Menthol Supplementation in Feedlot Cattle Diets on the Fecal Prevalence of Antimicrobial-Resistant Escherichia coli. 2016 PLoS ONE pmid:28030622
Webb CE and Hess IM A review of recommendations on the safe and effective use of topical mosquito repellents. 2016 Public Health Res Pract pmid:27997936
Wang HW et al. Menthol inhibiting parasympathetic function of tracheal smooth muscle. 2016 Int J Med Sci pmid:27994497
Oviedo A et al. Evaluation of the Tobacco Heating System 2.2. Part 6: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects of a mentholated version compared with mentholated and non-mentholated cigarette smoke. 2016 Regul. Toxicol. Pharmacol. pmid:27818348
Kogel U et al. Evaluation of the Tobacco Heating System 2.2. Part 7: Systems toxicological assessment of a mentholated version revealed reduced cellular and molecular exposure effects compared with mentholated and non-mentholated cigarette smoke. 2016 Regul. Toxicol. Pharmacol. pmid:27818347
Onuki Y et al. Effect of Surfactants and Thickeners on the Stability of Menthol-Diphenhydramine Cream Identified by Magnetic Resonance Imaging. 2016 Chem. Pharm. Bull. pmid:27803472
Lempert LK et al. Letter by Lempert et al Regarding Article, "Menthol and Nonmenthol Cigarette Smoking: All-Cause Deaths, Cardiovascular Disease Deaths, and Other Causes of Death Among Blacks and Whites". 2016 Circulation pmid:27572884
Cirlini M et al. Phenolic and Volatile Composition of a Dry Spearmint (Mentha spicata L.) Extract. 2016 Molecules pmid:27527127
Janssens A et al. Definition of two agonist types at the mammalian cold-activated channel TRPM8. 2016 Elife pmid:27449282
Chen GL et al. Borneol Is a TRPM8 Agonist that Increases Ocular Surface Wetness. 2016 PLoS ONE pmid:27448228
Sakellariou P et al. Chronic l-menthol-induced browning of white adipose tissue hypothesis: A putative therapeutic regime for combating obesity and improving metabolic health. 2016 Med. Hypotheses pmid:27372851
Phaechamud T and Tuntarawongsa S Transformation of eutectic emulsion to nanosuspension fabricating with solvent evaporation and ultrasonication technique. 2016 Int J Nanomedicine pmid:27366064
Sideris A et al. Cannabinoid 1 receptor knockout mice display cold allodynia, but enhanced recovery from spared-nerve injury-induced mechanical hypersensitivity. 2016 Mol Pain pmid:27206660
Kim HJ et al. Menthol Modulates Pacemaker Potentials through TRPA1 Channels in Cultured Interstitial Cells of Cajal from Murine Small Intestine. 2016 Cell. Physiol. Biochem. pmid:27160463
Craighead DH and Alexander LM Topical menthol increases cutaneous blood flow. 2016 Microvasc. Res. pmid:27131832
Pearson JL et al. The Moment Study: protocol for a mixed method observational cohort study of the Alternative Nicotine Delivery Systems (ANDS) initiation process among adult cigarette smokers. 2016 BMJ Open pmid:27105716
Sepulchro LC et al. Salinity does not alter the effectiveness of menthol as an anesthetic and sedative during the handling and transport of juvenile fat snook (Centropomus parallelus). 2016 Braz J Biol pmid:27097096
Van Bibber-Krueger CL et al. Effects of crystalline menthol on blood metabolites in Holstein steers and in vitro volatile fatty acid and gas production. 2016 J. Anim. Sci. pmid:27065278
Munro HM et al. Menthol and Nonmenthol Cigarette Smoking: All-Cause Deaths, Cardiovascular Disease Deaths, and Other Causes of Death Among Blacks and Whites. 2016 Circulation pmid:27022064
Henderson BJ et al. Menthol Alone Upregulates Midbrain nAChRs, Alters nAChR Subtype Stoichiometry, Alters Dopamine Neuron Firing Frequency, and Prevents Nicotine Reward. 2016 J. Neurosci. pmid:26961950
Ebihara T et al. A survey of subcutaneous blood flow in patients with SMID and subcutaneous ceftazidime administration using mentholated warm compresses in healthy subjects. 2016 J. Int. Med. Res. pmid:26912507
Rosbrook K and Green BG Sensory Effects of Menthol and Nicotine in an E-Cigarette. 2016 Nicotine Tob. Res. pmid:26783293
Faridi U et al. Repurposing L-Menthol for Systems Medicine and Cancer Therapeutics? L-Menthol Induces Apoptosis through Caspase 10 and by Suppressing HSP90. 2016 OMICS pmid:26760959
Ehrlich M et al. Analysis of metabolic effects of menthol on WFS1-deficient mice. 2016 Physiol Rep pmid:26733243
Tang M et al. Phosphoinositide interacting regulator of TRP (Pirt) enhances TRPM8 channel activity in vitro via increasing channel conductance. 2016 Acta Pharmacol. Sin. pmid:26657057
Rath P et al. Implications of Human Transient Receptor Potential Melastatin 8 (TRPM8) Channel Gating from Menthol Binding Studies of the Sensing Domain. 2016 Biochemistry pmid:26653082
Takaishi M et al. Reciprocal effects of capsaicin and menthol on thermosensation through regulated activities of TRPV1 and TRPM8. 2016 J Physiol Sci pmid:26645885
Matthews JL et al. Menthol-induced bleaching rapidly and effectively provides experimental aposymbiotic sea anemones (Aiptasia sp.) for symbiosis investigations. 2016 J. Exp. Biol. pmid:26596538
Ai J et al. Menthol Content in US Marketed Cigarettes. 2016 Nicotine Tob. Res. pmid:26259988
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Fagan P et al. Nicotine Metabolism in Young Adult Daily Menthol and Nonmenthol Smokers. 2016 Nicotine Tob. Res. pmid:25995160
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Kostygina G et al. Tobacco industry use of flavours to recruit new users of little cigars and cigarillos. 2016 Tob Control pmid:25354674
Bolcic-Jankovic D and Biener L Public opinion about FDA regulation of menthol and nicotine. 2015 Tob Control pmid:24638964
Ott D et al. Prostaglandin D2 modulates calcium signals induced by prostaglandin E2 in neurons of rat dorsal root ganglia. 2015 Neurosci. Lett. pmid:25912777
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Kikuchi H et al. CLINICAL APPLICATION OF L-MENTHOL IN THE UPPER GASTROINTESTINAL ENDOSCOPIC PROCEDURE. 2015 Fukushima J Med Sci pmid:26632191
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Wickham RJ How Menthol Alters Tobacco-Smoking Behavior: A Biological Perspective. 2015 Yale J Biol Med pmid:26339211
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Yates J Advice for protection against mosquitoes and ticks. 2015 Am Fam Physician pmid:26034848
Onuki Y et al. Magnetic resonance imaging study on the physical stability of menthol and diphenhydramine cream for the treatment of chronic kidney disease-associated pruritus. 2015 Chem. Pharm. Bull. pmid:26027471
Toogood HS et al. Enzymatic Menthol Production: One-Pot Approach Using Engineered Escherichia coli. 2015 ACS Synth Biol pmid:26017480
Ton HT et al. Menthol Enhances the Desensitization of Human α3β4 Nicotinic Acetylcholine Receptors. 2015 Mol. Pharmacol. pmid:25964258
Tran Trong T et al. Ingestion of a cold temperature/menthol beverage increases outdoor exercise performance in a hot, humid environment. 2015 PLoS ONE pmid:25856401
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Hoshino M et al. Effects of menthol on the pharmacokinetics of triazolam and phenytoin. 2015 Biol. Pharm. Bull. pmid:25757928
Fagan P et al. Comparisons of three nicotine dependence scales in a multiethnic sample of young adult menthol and non-menthol smokers. 2015 Drug Alcohol Depend pmid:25744873
Matsui R et al. Combination effect of physical and gustatory taste masking for propiverine hydrochloride orally disintegrating tablets on palatability. 2015 Biol. Pharm. Bull. pmid:25744453
Sharara AI et al. Split-dose menthol-enhanced PEG vs PEG-ascorbic acid for colonoscopy preparation. 2015 World J. Gastroenterol. pmid:25684963
Fallon MT et al. Cancer treatment-related neuropathic pain: proof of concept study with menthol--a TRPM8 agonist. 2015 Support Care Cancer pmid:25680765
Ha MA et al. Menthol attenuates respiratory irritation and elevates blood cotinine in cigarette smoke exposed mice. 2015 PLoS ONE pmid:25679525
Lehto SG et al. AMG2850, a potent and selective TRPM8 antagonist, is not effective in rat models of inflammatory mechanical hypersensitivity and neuropathic tactile allodynia. 2015 Naunyn Schmiedebergs Arch. Pharmacol. pmid:25662185
Wackowski OA et al. Switching to E-Cigarettes in the Event of a Menthol Cigarette Ban. 2015 Nicotine Tob. Res. pmid:25634935
Yu X et al. TRPM8 function and expression in vagal sensory neurons and afferent nerves innervating guinea pig esophagus. 2015 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:25591866
Choonara BF et al. A menthol-based solid dispersion technique for enhanced solubility and dissolution of sulfamethoxazole from an oral tablet matrix. 2015 AAPS PharmSciTech pmid:25549792
Liu BY et al. Menthol suppresses laryngeal C-fiber hypersensitivity to cigarette smoke in a rat model of gastroesophageal reflux disease: the role of TRPM8. 2015 J. Appl. Physiol. pmid:25539933
Rath JM et al. Patterns of Longitudinal Transitions in Menthol Use Among US Young Adult Smokers. 2015 Nicotine Tob. Res. pmid:25480932
Park SJ et al. Menthol cigarette smoking in the COPDGene cohort: relationship with COPD, comorbidities and CT metrics. 2015 Respirology pmid:25328036
Zuo Y et al. Sex-specific effects of cigarette mentholation on brain nicotine accumulation and smoking behavior. 2015 Neuropsychopharmacology pmid:25267342
Fallin A et al. Menthol cigarette smoking among lesbian, gay, bisexual, and transgender adults. 2015 Am J Prev Med pmid:25245795
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Jo CL et al. Tobacco products sold by Internet vendors following restrictions on flavors and light descriptors. 2015 Nicotine Tob. Res. pmid:25173777
Brennan E et al. Are young people's beliefs about menthol cigarettes associated with smoking-related intentions and behaviors? 2015 Nicotine Tob. Res. pmid:25151661
Míguez-Burbano MJ et al. Menthol cigarettes and the cardiovascular risks of people living with HIV. 2014 Sep-Oct J Assoc Nurses AIDS Care pmid:24581861
Ali A et al. New withanolide, acyl and menthyl glucosides from fruits of Withania coagulans Dunal. 2014 May-Jun Acta Pol Pharm pmid:25265822
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Curtin GM et al. Primary measures of dependence among menthol compared to non-menthol cigarette smokers in the United States. 2014 Regul. Toxicol. Pharmacol. pmid:24852490
da Silveira NS et al. The aversive, anxiolytic-like, and verapamil-sensitive psychostimulant effects of pulegone. 2014 Biol. Pharm. Bull. pmid:24790000
Lewis M et al. Tobacco control environment in the United States and individual consumer characteristics in relation to continued smoking: differential responses among menthol smokers? 2014 Prev Med pmid:24780527
Rossato M et al. Human white adipocytes express the cold receptor TRPM8 which activation induces UCP1 expression, mitochondrial activation and heat production. 2014 Mol. Cell. Endocrinol. pmid:24342393
Rozza AL et al. The gastroprotective effect of menthol: involvement of anti-apoptotic, antioxidant and anti-inflammatory activities. 2014 PLoS ONE pmid:24466200