| MeSH term | MeSH ID | Detail |
|---|---|---|
| Seizures | D012640 | 87 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
Total
3
Thujone
Thujone is a lipid of Prenol Lipids (PR) class. Thujone is associated with abnormalities such as Consumption-archaic term for TB, Malnutrition, Diabetes, abnormal fragmented structure and Dehydration. The involved functions are known as sabinene synthase activity, Anabolism, diterpene biosynthesis, Selection, Genetic and Biochemical Pathway. Thujone often locates in Tissue membrane, Clone, Epithelium, Back and Cell surface. The associated genes with Thujone are monoterpene synthase, Candidate Disease Gene, Recombinant Proteins, HM13 gene and DAND5 gene. The related lipids are Pinene, Palmitates and absinthium.
Cross Reference
Introduction
To understand associated biological information of Thujone, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with Thujone?
Thujone is suspected in Malnutrition, Diabetes, Dehydration and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with Thujone
PubChem Associated disorders and diseases
What pathways are associated with Thujone
Lipid pathways are not clear in current pathway databases. We organized associated pathways with Thujone through full-text articles, including metabolic pathways or pathways of biological mechanisms.
Related references are published most in these journals:
| Pathway name | Related literatures |
|---|
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PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with Thujone?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with Thujone?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with Thujone?
Related references are published most in these journals:
- Proc. Natl. Acad. Sci. U.S.A. (1)
- Am. J. Physiol. Regul. Integr. Comp. Physiol. (1)
- Plant Physiol. (1)
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with Thujone?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with Thujone?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with Thujone
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gesell A et al. | The gymnosperm cytochrome P450 CYP750B1 catalyzes stereospecific monoterpene hydroxylation of (+)-sabinene in thujone biosynthesis in western redcedar. | 2015 | Plant Physiol. | pmid:25829465 |
| Karban R et al. | Deciphering the language of plant communication: volatile chemotypes of sagebrush. | 2014 | New Phytol. | pmid:24920243 |
| Rivera EM et al. | Central α- and β-thujone: similar anxiogenic-like effects and differential modulation on GABAA receptors in neonatal chicks. | 2014 | Brain Res. | pmid:24486357 |
| D'Ulivo L | The absinthe challenge. | 2014 | Anal Bioanal Chem | pmid:24632744 |
| Horváth G et al. | TLC-direct bioautography for determination of antibacterial activity of Artemisia adamsii essential oil. | 2013 Nov-Dec | J AOAC Int | pmid:24645495 |
| Arceusz A et al. | Comparison of different extraction methods for the determination of α- and β-thujone in sage (Salvia officinalis L.) herbal tea. | 2013 | J Sep Sci | pmid:23843295 |
| Waidyanatha S et al. | Toxicokinetics of α-thujone following intravenous and gavage administration of α-thujone or α- and β-thujone mixture in male and female F344/N rats and B6C3F1 mice. | 2013 | Toxicol. Appl. Pharmacol. | pmid:23669748 |
| Pelkonen O et al. | Thujone and thujone-containing herbal medicinal and botanical products: toxicological assessment. | 2013 | Regul. Toxicol. Pharmacol. | pmid:23201408 |
| Foster AJ et al. | Identification of genes in Thuja plicata foliar terpenoid defenses. | 2013 | Plant Physiol. | pmid:23388118 |
| Czyzewska MM and Mozrzymas JW | Monoterpene α-thujone exerts a differential inhibitory action on GABA(A) receptors implicated in phasic and tonic GABAergic inhibition. | 2013 | Eur. J. Pharmacol. | pmid:23376563 |