KDO2-lipid A

KDO2-lipid A is a lipid of Saccharolipids (SL) class. The involved functions are known as Biochemical Pathway, Immune response, Anabolism, Signal Transduction and Stimulus. Kdo2-lipid a often locates in Immune system and Protoplasm. The associated genes with KDO2-lipid A are PSMD6 gene, ABCA1 gene, ABCG1 gene, DHCR24 gene and SOAT1 gene. The related lipids are Lipopolysaccharides, Sterols, Fatty Acids, 25-hydroxycholesterol and lipid IVA.

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Introduction

To understand associated biological information of KDO2-lipid A, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with KDO2-lipid A?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with KDO2-lipid A

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with KDO2-lipid A?

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What functions are associated with KDO2-lipid A?


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What lipids are associated with KDO2-lipid A?

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What genes are associated with KDO2-lipid A?

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What common seen animal models are associated with KDO2-lipid A?

There are no associated biomedical information in the current reference collection.

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All references with KDO2-lipid A

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Authors Title Published Journal PubMed Link
pmid:
Murphy RC et al. Mass spectrometry advances in lipidomica: collision-induced decomposition of Kdo2-lipid A. 2005 Prostaglandins Other Lipid Mediat. pmid:16099398
Zughaier S et al. Hexa-acylation and KDO(2)-glycosylation determine the specific immunostimulatory activity of Neisseria meningitidis lipid A for human monocyte derived dendritic cells. 2006 Vaccine pmid:16246469
Raetz CR et al. Kdo2-Lipid A of Escherichia coli, a defined endotoxin that activates macrophages via TLR-4. 2006 J. Lipid Res. pmid:16479018
Raetz CR et al. Lipid A modification systems in gram-negative bacteria. 2007 Annu. Rev. Biochem. pmid:17362200
Murphy RC et al. Detection of the abundance of diacylglycerol and triacylglycerol molecular species in cells using neutral loss mass spectrometry. 2007 Anal. Biochem. pmid:17442253
Albright S et al. NMR spectral mapping of Lipid A molecular patterns affected by interaction with the innate immune receptor CD14. 2009 Biochem. Biophys. Res. Commun. pmid:19059378
Delcour AH Outer membrane permeability and antibiotic resistance. 2009 Biochim. Biophys. Acta pmid:19100346
Grkovich A et al. TLR-4 mediated group IVA phospholipase A(2) activation is phosphatidic acid phosphohydrolase 1 and protein kinase C dependent. 2009 Biochim. Biophys. Acta pmid:19230851
Wang X and Quinn PJ Lipopolysaccharide: Biosynthetic pathway and structure modification. 2010 Prog. Lipid Res. pmid:19815028