| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Zhang G et al. | Anti-inflammatory activities and glycerophospholipids metabolism in KLA-stimulated RAW 264.7 macrophage cells by diarylheptanoids from the rhizomes of Alpinia officinarum. | 2018 | Biomed. Chromatogr. | pmid:28906002 |
| Oishi Y et al. | SREBP1 Contributes to Resolution of Pro-inflammatory TLR4 Signaling by Reprogramming Fatty Acid Metabolism. | 2017 | Cell Metab. | pmid:28041958 |
| Wang B et al. | Immuno-Stimulatory Activity of Escherichia coli Mutants Producing Kdo2-Monophosphoryl-Lipid A or Kdo2-Pentaacyl-Monophosphoryl-Lipid A. | 2015 | PLoS ONE | pmid:26710252 |
| Klein G and Raina S | Regulated Control of the Assembly and Diversity of LPS by Noncoding sRNAs. | 2015 | Biomed Res Int | pmid:26618164 |
| Mudapaka J and Taylor EA | Cloning and characterization of the Escherichia coli Heptosyltransferase III: Exploring substrate specificity in lipopolysaccharide core biosynthesis. | 2015 | FEBS Lett. | pmid:25957775 |
| Andreev K et al. | Guanidino groups greatly enhance the action of antimicrobial peptidomimetics against bacterial cytoplasmic membranes. | 2014 | Biochim. Biophys. Acta | pmid:24878450 |
| Wang J et al. | Construction and characterization of an Escherichia coli mutant producing Kdoâ‚‚-lipid A. | 2014 | Mar Drugs | pmid:24633251 |
| Kihara Y et al. | Modeling of eicosanoid fluxes reveals functional coupling between cyclooxygenases and terminal synthases. | 2014 | Biophys. J. | pmid:24559999 |
| Chung HS et al. | Kdo hydroxylase is an inner core assembly enzyme in the Ko-containing lipopolysaccharide biosynthesis. | 2014 | Biochem. Biophys. Res. Commun. | pmid:25204504 |
| Wang X | [Kdo2-lipid A modification in gram-negative bacteria--a review]. | 2013 | Wei Sheng Wu Xue Bao | pmid:23627103 |
| Maurya MR et al. | Analysis of inflammatory and lipid metabolic networks across RAW264.7 and thioglycolate-elicited macrophages. | 2013 | J. Lipid Res. | pmid:23776196 |
| Dinasarapu AR et al. | A combined omics study on activated macrophages--enhanced role of STATs in apoptosis, immunity and lipid metabolism. | 2013 | Bioinformatics | pmid:23981351 |
| Sabidó E et al. | Targeted proteomics of the eicosanoid biosynthetic pathway completes an integrated genomics-proteomics-metabolomics picture of cellular metabolism. | 2012 | Mol. Cell Proteomics | pmid:22361236 |
| Zheng X et al. | Crosstalk between JNK and NF-κB in the KDO2-mediated production of TNFα in HAPI cells. | 2012 | Cell. Mol. Neurobiol. | pmid:22837047 |
| Norris PC and Dennis EA | Omega-3 fatty acids cause dramatic changes in TLR4 and purinergic eicosanoid signaling. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:22586114 |
| Opiyo SO et al. | Evolution of the Kdo2-lipid A biosynthesis in bacteria. | 2010 | BMC Evol. Biol. | pmid:21106097 |
| Dennis EA et al. | A mouse macrophage lipidome. | 2010 | J. Biol. Chem. | pmid:20923771 |
| Sims K et al. | Kdo2-lipid A, a TLR4-specific agonist, induces de novo sphingolipid biosynthesis in RAW264.7 macrophages, which is essential for induction of autophagy. | 2010 | J. Biol. Chem. | pmid:20876532 |
| Kim EY et al. | ATF3 plays a key role in Kdo2-lipid A-induced TLR4-dependent gene expression via NF-κB activation. | 2010 | PLoS ONE | pmid:21152039 |
| Saito O et al. | Spinal glial TLR4-mediated nociception and production of prostaglandin E(2) and TNF. | 2010 | Br. J. Pharmacol. | pmid:20649577 |
KDO2-lipid A
KDO2-lipid A is a lipid of Saccharolipids (SL) class. The involved functions are known as Biochemical Pathway, Immune response, Anabolism, Signal Transduction and Stimulus. Kdo2-lipid a often locates in Immune system and Protoplasm. The associated genes with KDO2-lipid A are PSMD6 gene, ABCA1 gene, ABCG1 gene, DHCR24 gene and SOAT1 gene. The related lipids are Lipopolysaccharides, Sterols, Fatty Acids, 25-hydroxycholesterol and lipid IVA.
Cross Reference
Introduction
To understand associated biological information of KDO2-lipid A, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with KDO2-lipid A?
There are no associated biomedical information in the current reference collection.
No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with KDO2-lipid A
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with KDO2-lipid A?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with KDO2-lipid A?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with KDO2-lipid A?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with KDO2-lipid A?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with KDO2-lipid A?
There are no associated biomedical information in the current reference collection.