Enigmol

Enigmol is a lipid of Sphingolipids (SP) class. Enigmol is associated with abnormalities such as Dehydration and athymia. The involved functions are known as metaplastic cell transformation, Metabolic Inhibition, Selection, Genetic, Stereochemistry and N acylation. Enigmol often locates in Cytoplasmic matrix, Left lateral lumbar region of abdomen, soluble, Blood and Tissue membrane. The associated genes with Enigmol are MSMP gene, APC gene, Oncogenes, SPATA6 gene and FATE1 gene. The related lipids are Sphingolipids and Fatty Acids. The related experimental models are Xenograft Model, Mouse Model and Cancer Model.

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Introduction

To understand associated biological information of Enigmol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Enigmol?

Enigmol is suspected in athymia, Dehydration and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Enigmol

MeSH term MeSH ID Detail
Prostatic Neoplasms D011471 126 associated lipids
Total 1

PubChem Associated disorders and diseases

What pathways are associated with Enigmol

Lipid pathways are not clear in current pathway databases. We organized associated pathways with Enigmol through full-text articles, including metabolic pathways or pathways of biological mechanisms.

Related references are published most in these journals:

Pathway name Related literatures
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PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Enigmol?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Enigmol?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Enigmol?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with Enigmol?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with Enigmol?

Mouse Model

Mouse Model are used in the study 'Enigmol: a novel sphingolipid analogue with anticancer activity against cancer cell lines and in vivo models for intestinal and prostate cancer.' (Symolon H et al., 2011).

Xenograft Model

Xenograft Model are used in the study 'Enigmol: a novel sphingolipid analogue with anticancer activity against cancer cell lines and in vivo models for intestinal and prostate cancer.' (Symolon H et al., 2011).

Cancer Model

Cancer Model are used in the study 'Enigmol: a novel sphingolipid analogue with anticancer activity against cancer cell lines and in vivo models for intestinal and prostate cancer.' (Symolon H et al., 2011).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
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NCBI Entrez Crosslinks

All references with Enigmol

Download all related citations
Total 5
Authors Title Published Journal PubMed Link
Meyer EV et al. Sphingolipid analogues inhibit development of malaria parasites. 2012 ACS Med Chem Lett pmid:24900369
Merrill AH Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics. 2011 Chem. Rev. pmid:21942574
Symolon H et al. Enigmol: a novel sphingolipid analogue with anticancer activity against cancer cell lines and in vivo models for intestinal and prostate cancer. 2011 Mol. Cancer Ther. pmid:21398423
Garnier-Amblard EC et al. Novel synthesis and biological evaluation of enigmols as therapeutic agents for treating prostate cancer. 2011 ACS Med Chem Lett pmid:24900327
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