octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Ischemic Attack, Transient D002546 42 associated lipids
Gastrointestinal Diseases D005767 20 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Reye Syndrome D012202 14 associated lipids
Poultry Diseases D011201 21 associated lipids
Jaundice, Neonatal D007567 7 associated lipids
Parkinson Disease D010300 53 associated lipids
Blind Loop Syndrome D001765 3 associated lipids
Coccidiosis D003048 3 associated lipids
Schistosomiasis D012552 4 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Augustin K et al. Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders. 2018 Lancet Neurol pmid:29263011
Murtuza MI and Isokawa M Endogenous ghrelin-O-acyltransferase (GOAT) acylates local ghrelin in the hippocampus. 2018 J. Neurochem. pmid:29063591
Vacchina P et al. Lipoic acid metabolism in Trypanosoma cruzi as putative target for chemotherapy. 2018 Exp. Parasitol. pmid:29409741
Khabbush A et al. Neuronal decanoic acid oxidation is markedly lower than that of octanoic acid: A mechanistic insight into the medium-chain triglyceride ketogenic diet. 2017 Epilepsia pmid:28682459
Kawai A et al. Crystallographic analysis of the ternary complex of octanoate and N-acetyl-l-methionine with human serum albumin reveals the mode of their stabilizing interactions. 2017 Biochim Biophys Acta Proteins Proteom pmid:28473296
Du J et al. Molecular basis of P450 OleT: an investigation of substrate binding mechanism and major pathways. 2017 J. Comput. Aided Mol. Des. pmid:28342136
Besada-Lombana PB et al. Engineering Saccharomyces cerevisiae fatty acid composition for increased tolerance to octanoic acid. 2017 Biotechnol. Bioeng. pmid:28294288
Hsieh CH et al. The Enigmatic P450 Decarboxylase OleT Is Capable of, but Evolved To Frustrate, Oxygen Rebound Chemistry. 2017 Biochemistry pmid:28603981
Centeno JA et al. Recovering traditional raw-milk Tetilla cheese flavour and sensory attributes by using Kocuria varians and Yarrowia lipolytica adjunct cultures. 2017 Int. J. Food Microbiol. pmid:28384620
Alva-Murillo N et al. Sodium Octanoate Modulates the Innate Immune Response of Bovine Mammary Epithelial Cells through the TLR2/P38/JNK/ERK1/2 Pathway: Implications during Staphylococcus aureus Internalization. 2017 Front Cell Infect Microbiol pmid:28361042