octanoic acid

octanoic acid is a lipid of Fatty Acyls (FA) class. Octanoic acid is associated with abnormalities such as Ischemia, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes, Cardiomyopathies and Obesity. The involved functions are known as Anabolism, 5-(carboxyamino)imidazole ribonucleotide mutase activity, Citric Acid Cycle, Metabolic Inhibition and Excretory function. Octanoic acid often locates in Pore, Protoplasm, Endothelium, Mitochondria and Muscle. The associated genes with octanoic acid are P4HTM gene, CPT1A gene, HADH gene, ACSL1 Gene and CD36 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, Oleates, Palmitates and hexanoic acid.

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Introduction

To understand associated biological information of octanoic acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with octanoic acid?

octanoic acid is suspected in Obesity, Atherosclerosis, Gigantism, Alzheimer's Disease, Neurodegenerative Disorders, Cardiomyopathies and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with octanoic acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Stomach Diseases D013272 7 associated lipids
Inflammation D007249 119 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with octanoic acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with octanoic acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with octanoic acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with octanoic acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with octanoic acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with octanoic acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with octanoic acid

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Authors Title Published Journal PubMed Link
Augustin K et al. Mechanisms of action for the medium-chain triglyceride ketogenic diet in neurological and metabolic disorders. 2018 Lancet Neurol pmid:29263011
Murtuza MI and Isokawa M Endogenous ghrelin-O-acyltransferase (GOAT) acylates local ghrelin in the hippocampus. 2018 J. Neurochem. pmid:29063591
Vacchina P et al. Lipoic acid metabolism in Trypanosoma cruzi as putative target for chemotherapy. 2018 Exp. Parasitol. pmid:29409741
Saito K et al. An in vitro skin sensitization assay termed EpiSensA for broad sets of chemicals including lipophilic chemicals and pre/pro-haptens. 2017 Toxicol In Vitro pmid:27965148
Caviglia GP et al. Gastric emptying and related symptoms in patients treated with buspirone, amitriptyline or clebopride: a "real world" study by 13C-octanoic Acid Breath Test. 2017 Minerva Med. pmid:28707862
Khabbush A et al. Neuronal decanoic acid oxidation is markedly lower than that of octanoic acid: A mechanistic insight into the medium-chain triglyceride ketogenic diet. 2017 Epilepsia pmid:28682459
Kawai A et al. Crystallographic analysis of the ternary complex of octanoate and N-acetyl-l-methionine with human serum albumin reveals the mode of their stabilizing interactions. 2017 Biochim Biophys Acta Proteins Proteom pmid:28473296
Du J et al. Molecular basis of P450 OleT: an investigation of substrate binding mechanism and major pathways. 2017 J. Comput. Aided Mol. Des. pmid:28342136
Besada-Lombana PB et al. Engineering Saccharomyces cerevisiae fatty acid composition for increased tolerance to octanoic acid. 2017 Biotechnol. Bioeng. pmid:28294288
Lourenço A et al. Antimicrobial treatments to control Listeria monocytogenes in queso fresco. 2017 Food Microbiol. pmid:28213034
Fontaine P et al. Medium chain length polyhydroxyalkanoates biosynthesis in Pseudomonas putida mt-2 is enhanced by co-metabolism of glycerol/octanoate or fatty acids mixtures. 2017 Int. J. Biol. Macromol. pmid:28174083
Das K and Ghosh M Structured DAG oil ameliorates renal injury in streptozotocin-induced diabetic rats through inhibition of NF-κB and activation of Nrf2 pathway. 2017 Food Chem. Toxicol. pmid:28025123
Vanheel H et al. Pathophysiological Abnormalities in Functional Dyspepsia Subgroups According to the Rome III Criteria. 2017 Am. J. Gastroenterol. pmid:27958284
Clarke D et al. Surface attachment of active antimicrobial coatings onto conventional plastic-based laminates and performance assessment of these materials on the storage life of vacuum packaged beef sub-primals. 2017 Food Microbiol. pmid:27889148
Jadhav A et al. The Dietary Food Components Capric Acid and Caprylic Acid Inhibit Virulence Factors in Candida albicans Through Multitargeting. 2017 J Med Food pmid:28922057
Goussen C et al. Biological Safety of a Highly Purified 10% Liquid Intravenous Immunoglobulin Preparation from Human Plasma. 2017 BioDrugs pmid:28508264
Peyser RD et al. Analysis of cytochrome P450 contribution to evolved plant toxin resistance in Drosophila sechellia. 2017 Insect Mol. Biol. pmid:28703934
Hsieh CH et al. The Enigmatic P450 Decarboxylase OleT Is Capable of, but Evolved To Frustrate, Oxygen Rebound Chemistry. 2017 Biochemistry pmid:28603981
Centeno JA et al. Recovering traditional raw-milk Tetilla cheese flavour and sensory attributes by using Kocuria varians and Yarrowia lipolytica adjunct cultures. 2017 Int. J. Food Microbiol. pmid:28384620
Zhang K et al. Regulation of the Docosapentaenoic Acid/Docosahexaenoic Acid Ratio (DPA/DHA Ratio) in Schizochytrium limacinum B4D1. 2017 Appl. Biochem. Biotechnol. pmid:27832512