| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| pmid: | ||||
| Aubry AF et al. | Recommendations on the Development of a Bioanalytical Assay for 4β-Hydroxycholesterol, an Emerging Endogenous Biomarker of CYP3A Activity. | 2016 | AAPS J | pmid:27350147 |
| Björkhem-Bergman L et al. | Effect of Statin Treatment on Plasma 4β-Hydroxycholesterol Concentrations. | 2016 | Basic Clin. Pharmacol. Toxicol. | pmid:26617265 |
| Woolsey SJ et al. | Relationships between Endogenous Plasma Biomarkers of Constitutive Cytochrome P450 3A Activity and Single-Time-Point Oral Midazolam Microdose Phenotype in Healthy Subjects. | 2016 | Basic Clin. Pharmacol. Toxicol. | pmid:26399557 |
| Nylén H et al. | Plasma levels of 25-hydroxyvitamin D3 and in vivo markers of cytochrome P450 3A activity in Swedes and Koreans: effects of a genetic polymorphism and oral contraceptives. | 2014 | Basic Clin. Pharmacol. Toxicol. | pmid:24655660 |
| Allmyr M et al. | Human exposure to triclosan via toothpaste does not change CYP3A4 activity or plasma concentrations of thyroid hormones. | 2009 | Basic Clin. Pharmacol. Toxicol. | pmid:19686543 |
| van de Merbel NC and de Vries R | Aging of biological matrices and its effect on bioanalytical method performance. | 2013 | Bioanalysis | pmid:24066624 |
| Xue YJ et al. | Use of 4β-hydroxycholesterol in animal and human plasma samples as a biomarker for CYP3A induction. | 2016 | Bioanalysis | pmid:26805594 |
| Ikegami T et al. | Increased serum oxysterol concentrations in patients with chronic hepatitis C virus infection. | 2014 | Biochem. Biophys. Res. Commun. | pmid:24525121 |
| Breuer O et al. | The oxysterols cholest-5-ene-3 beta,4 alpha-diol, cholest-5-ene-3 beta,4 beta-diol and cholestane-3 beta,5 alpha,6 alpha-triol are formed during in vitro oxidation of low density lipoprotein, and are present in human atherosclerotic plaques. | 1996 | Biochim. Biophys. Acta | pmid:8695664 |
4beta-Hydroxycholesterol
4beta-Hydroxycholesterol is a lipid of Sterol Lipids (ST) class. 4beta-hydroxycholesterol is associated with abnormalities such as Kidney Failure, Kidney Failure, Chronic, Respiratory Tract Infections, Immunologic Deficiency Syndromes and Infection. The involved functions are known as Selection, Genetic, Renal function, Anabolism, Inflammation and Cell division phases. 4beta-hydroxycholesterol often locates in Hepatic, Blood, Skin and Microsomes. The associated genes with 4beta-Hydroxycholesterol are CYP3A5 gene, Alleles, TERT gene, CYP3A4 gene and CYP3A7 gene. The related lipids are 4-hydroxycholesterol, Hydroxycholesterols, Promega, Pregnanes and 24-hydroxycholesterol.
Cross Reference
Introduction
To understand associated biological information of 4beta-Hydroxycholesterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4beta-Hydroxycholesterol?
4beta-Hydroxycholesterol is suspected in Kidney Failure, Chronic, Kidney Failure, Respiratory Tract Infections, Immunologic Deficiency Syndromes, Infection, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with 4beta-Hydroxycholesterol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4beta-Hydroxycholesterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with 4beta-Hydroxycholesterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 4beta-Hydroxycholesterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 4beta-Hydroxycholesterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with 4beta-Hydroxycholesterol?
There are no associated biomedical information in the current reference collection.