| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nury T et al. | Biological activities of the LXRα and β agonist, 4β-hydroxycholesterol, and of its isomer, 4α-hydroxycholesterol, on oligodendrocytes: effects on cell growth and viability, oxidative and inflammatory status. | 2013 | Biochimie | pmid:23220593 |
| Huang MQ et al. | Quantitation of P450 3A4 endogenous biomarker - 4β-hydroxycholesterol - in human plasma using LC/ESI-MS/MS. | 2014 | Biomed. Chromatogr. | pmid:24861746 |
| Wide K et al. | Time course of the increase in 4beta-hydroxycholesterol concentration during carbamazepine treatment of paediatric patients with epilepsy. | 2008 | Br J Clin Pharmacol | pmid:18279471 |
| Hukkanen J et al. | The effect of atorvastatin treatment on serum oxysterol concentrations and cytochrome P450 3A4 activity. | 2015 | Br J Clin Pharmacol | pmid:26095142 |
| Gjestad C et al. | 4β-hydroxycholesterol correlates with dose but not steady-state concentration of carbamazepine: indication of intestinal CYP3A in biomarker formation? | 2016 | Br J Clin Pharmacol | pmid:26574235 |
| de Graan AJ et al. | 4β-hydroxycholesterol as an endogenous CYP3A marker in cancer patients treated with taxanes. | 2015 | Br J Clin Pharmacol | pmid:26119961 |
| Kasichayanula S et al. | Validation of 4β-hydroxycholesterol and evaluation of other endogenous biomarkers for the assessment of CYP3A activity in healthy subjects. | 2014 | Br J Clin Pharmacol | pmid:24837659 |
| Vanhove T et al. | Comparative performance of oral midazolam clearance and plasma 4β-hydroxycholesterol to explain interindividual variability in tacrolimus clearance. | 2016 | Br J Clin Pharmacol | pmid:27501475 |
| Størset E et al. | The CYP3A biomarker 4β-hydroxycholesterol does not improve tacrolimus dose predictions early after kidney transplantation. | 2017 | Br J Clin Pharmacol | pmid:28146606 |
| Vanhove T et al. | Pretransplant 4β-hydroxycholesterol does not predict tacrolimus exposure or dose requirements during the first days after kidney transplantation. | 2017 | Br J Clin Pharmacol | pmid:28603840 |
4beta-Hydroxycholesterol
4beta-Hydroxycholesterol is a lipid of Sterol Lipids (ST) class. 4beta-hydroxycholesterol is associated with abnormalities such as Kidney Failure, Kidney Failure, Chronic, Respiratory Tract Infections, Immunologic Deficiency Syndromes and Infection. The involved functions are known as Selection, Genetic, Renal function, Anabolism, Inflammation and Cell division phases. 4beta-hydroxycholesterol often locates in Hepatic, Blood, Skin and Microsomes. The associated genes with 4beta-Hydroxycholesterol are CYP3A5 gene, Alleles, TERT gene, CYP3A4 gene and CYP3A7 gene. The related lipids are 4-hydroxycholesterol, Hydroxycholesterols, Promega, Pregnanes and 24-hydroxycholesterol.
Cross Reference
Introduction
To understand associated biological information of 4beta-Hydroxycholesterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4beta-Hydroxycholesterol?
4beta-Hydroxycholesterol is suspected in Kidney Failure, Chronic, Kidney Failure, Respiratory Tract Infections, Immunologic Deficiency Syndromes, Infection, Epilepsy and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with 4beta-Hydroxycholesterol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4beta-Hydroxycholesterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with 4beta-Hydroxycholesterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 4beta-Hydroxycholesterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 4beta-Hydroxycholesterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with 4beta-Hydroxycholesterol?
There are no associated biomedical information in the current reference collection.