Cucurbitacin D

Cucurbitacin d is a lipid of Sterol Lipids (ST) class. The involved functions are known as Transcription, Genetic. Cucurbitacin d often locates in Membrane.

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Introduction

To understand associated biological information of Cucurbitacin D, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Cucurbitacin D?

There are no associated biomedical information in the current reference collection.

No disease MeSH terms mapped to the current reference collection.

PubChem Associated disorders and diseases

What pathways are associated with Cucurbitacin D

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Cucurbitacin D?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Cucurbitacin D?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Cucurbitacin D?

There are no associated biomedical information in the current reference collection.

What genes are associated with Cucurbitacin D?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Cucurbitacin D?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Cucurbitacin D

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Authors Title Published Journal PubMed Link
Ku JM et al. Cucurbitacin D induces cell cycle arrest and apoptosis by inhibiting STAT3 and NF-κB signaling in doxorubicin-resistant human breast carcinoma (MCF7/ADR) cells. 2015 Mol. Cell. Biochem. pmid:26169986
Jacquot C et al. Cucurbitacin-D-induced CDK1 mRNA up-regulation causes proliferation arrest of a non-small cell lung carcinoma cell line (NSCLC-N6). 2014 Anticancer Res. pmid:25202060
Abbas S et al. The cucurbitacins E, D and I: investigation of their cytotoxicity toward human chondrosarcoma SW 1353 cell line and their biotransformation in man liver. 2013 Toxicol. Lett. pmid:23194827
Ishii T et al. Cucurbitacin D induces growth inhibition, cell cycle arrest, and apoptosis in human endometrial and ovarian cancer cells. 2013 Tumour Biol. pmid:23150173
Spear SA et al. Natural compounds as potential treatments of NF2-deficient schwannoma and meningioma: cucurbitacin D and goyazensolide. 2013 Otol. Neurotol. pmid:23928514
Song Y et al. Cucurbitacin D is a new inflammasome activator in macrophages. 2013 Int. Immunopharmacol. pmid:24140411
Ding N et al. Apoptosis induction through proteasome inhibitory activity of cucurbitacin D in human T-cell leukemia. 2011 Cancer pmid:21656752
Jung ME and Lui RM Studies toward the total syntheses of cucurbitacins B and D. 2010 J. Org. Chem. pmid:20873743
Sahranavard S et al. New cucurbitane-type triterpenoids from Bryonia aspera. 2010 Planta Med. pmid:20108178
Abou-Khalil R et al. Interaction of cucurbitacins with human serum albumin: Thermodynamic characteristics and influence on the binding of site specific ligands. 2009 J. Photochem. Photobiol. B, Biol. pmid:19380237