| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sukhanova A et al. | Targeting C4-demethylating genes in the cholesterol pathway sensitizes cancer cells to EGF receptor inhibitors via increased EGF receptor degradation. | 2013 | Cancer Discov | pmid:23125191 |
| Gleason JE et al. | Analysis of hypoxia and hypoxia-like states through metabolite profiling. | 2011 | PLoS ONE | pmid:21931840 |
| Sugai M et al. | Characterization of sterol lipids in Kluyveromyces lactis strain M-16 accumulating a high amount of steryl glucoside. | 2009 | J Oleo Sci | pmid:19145063 |
| Vinci G et al. | Preservation of genes involved in sterol metabolism in cholesterol auxotrophs: facts and hypotheses. | 2008 | PLoS ONE | pmid:18682733 |
| Hu W et al. | Essential gene identification and drug target prioritization in Aspergillus fumigatus. | 2007 | PLoS Pathog. | pmid:17352532 |
| Germann M et al. | Characterizing sterol defect suppressors uncovers a novel transcriptional signaling pathway regulating zymosterol biosynthesis. | 2005 | J. Biol. Chem. | pmid:16120615 |
| Mo C et al. | The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p). | 2004 | Biochim. Biophys. Acta | pmid:15522820 |
| Darnet S and Rahier A | Enzymological properties of sterol-C4-methyl-oxidase of yeast sterol biosynthesis. | 2003 | Biochim. Biophys. Acta | pmid:12880870 |
| Mo C et al. | In yeast sterol biosynthesis the 3-keto reductase protein (Erg27p) is required for oxidosqualene cyclase (Erg7p) activity. | 2003 | Biochim. Biophys. Acta | pmid:12842197 |
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4,4-dimethylzymosterol
4,4-dimethylzymosterol is a lipid of Sterol Lipids (ST) class. The involved functions are known as Synthesis, Anabolism, sphingolipid biosynthesis, Permissiveness, Biological Function and ergosterol biosynthesis. 4,4-dimethylzymosterol often locates in Microsomes, Protoplasm and Face. The associated genes with 4,4-dimethylzymosterol are DLC1 gene. The related lipids are Sterols, zymosterol, Cholestenones, coprostanone and Sphingolipids.
Cross Reference
Introduction
To understand associated biological information of 4,4-dimethylzymosterol, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 4,4-dimethylzymosterol?
There are no associated biomedical information in the current reference collection.
No disease MeSH terms mapped to the current reference collection.
PubChem Associated disorders and diseases
What pathways are associated with 4,4-dimethylzymosterol
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 4,4-dimethylzymosterol?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with 4,4-dimethylzymosterol?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 4,4-dimethylzymosterol?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 4,4-dimethylzymosterol?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with 4,4-dimethylzymosterol?
There are no associated biomedical information in the current reference collection.