15-epi-lxa4;15r-lxa4

15-epi-lxa4;15r-lxa4 is a lipid of Fatty Acyls (FA) class. 15-epi-lxa4;15r-lxa4 is associated with abnormalities such as Pneumonia, Septicemia, Cystic Fibrosis, Subarachnoid Hemorrhage and Obesity. The involved functions are known as Protective Agents, Signal Transduction, cytokine biosynthesis, Inflammation and Anabolism. 15-epi-lxa4;15r-lxa4 often locates in Blood, Immune system and Heart tissue. The associated genes with 15-epi-lxa4;15r-lxa4 are IL2 gene, CXCL13 gene and CMKLR1 gene. The related lipids are Steroids. The related experimental models are Knock-out.

Cross Reference

Introduction

To understand associated biological information of 15-epi-lxa4;15r-lxa4, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 15-epi-lxa4;15r-lxa4?

15-epi-lxa4;15r-lxa4 is suspected in Cystic Fibrosis, Asthma, Chagas Cardiomyopathy, Pneumonia, Septicemia, Subarachnoid Hemorrhage and other diseases in descending order of the highest number of associated sentences.

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Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 15-epi-lxa4;15r-lxa4

PubChem Associated disorders and diseases

What pathways are associated with 15-epi-lxa4;15r-lxa4

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 15-epi-lxa4;15r-lxa4?

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What functions are associated with 15-epi-lxa4;15r-lxa4?


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What lipids are associated with 15-epi-lxa4;15r-lxa4?

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What genes are associated with 15-epi-lxa4;15r-lxa4?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 15-epi-lxa4;15r-lxa4?

Knock-out

Knock-out are used in the study 'Aspirin-triggered 15-epi-lipoxin A4 regulates neutrophil-platelet aggregation and attenuates acute lung injury in mice.' (Ortiz-Muñoz G et al., 2014).

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NCBI Entrez Crosslinks

All references with 15-epi-lxa4;15r-lxa4

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Authors Title Published Journal PubMed Link
Anuforo OUU et al. Natural killer cells play an essential role in resolution of antigen-induced inflammation in mice. 2018 Mol. Immunol. pmid:29112834
Muralikumar S et al. Probing the intermolecular interactions of PPARγ-LBD with polyunsaturated fatty acids and their anti-inflammatory metabolites to infer most potential binding moieties. 2017 Lipids Health Dis pmid:28109294
Singh A et al. Lipoxin A4, a 5-lipoxygenase pathway metabolite, modulates immune response during acute respiratory tularemia. 2017 J. Leukoc. Biol. pmid:27630217
Reis MB et al. Lipoxin A4 encapsulated in PLGA microparticles accelerates wound healing of skin ulcers. 2017 PLoS ONE pmid:28753648
Yang Y et al. The effects of different frequency treadmill exercise on lipoxin A4 and articular cartilage degeneration in an experimental model of monosodium iodoacetate-induced osteoarthritis in rats. 2017 PLoS ONE pmid:28594958
Shi Y et al. Lipoxin A4 mitigates experimental autoimmune myocarditis by regulating inflammatory response, NF-κB and PI3K/Akt signaling pathway in mice. 2017 Eur Rev Med Pharmacol Sci pmid:28485793
Wu SH et al. Signal transduction involved in lipoxin A4‑induced protection of tubular epithelial cells against hypoxia/reoxygenation injury. 2017 Mol Med Rep pmid:28259922
González-Herrera F et al. Simvastatin Attenuates Endothelial Activation through 15-Epi-Lipoxin A4 Production in Murine Chronic Chagas Cardiomyopathy. 2017 Antimicrob. Agents Chemother. pmid:27993857
Hodges RR et al. Lipoxin A4 activates ALX/FPR2 receptor to regulate conjunctival goblet cell secretion. 2017 Mucosal Immunol pmid:27072607
Diaz-Gerevini GT et al. Beneficial action of resveratrol: How and why? 2016 Nutrition pmid:26706021