Propionylcarnitine

Propionylcarnitine is a lipid of Fatty Acyls (FA) class. Propionylcarnitine is associated with abnormalities such as Failure to Thrive. The involved functions are known as Functional disorder. Propionylcarnitine often locates in Body tissue.

Cross Reference

Introduction

To understand associated biological information of Propionylcarnitine, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with Propionylcarnitine?

Propionylcarnitine is suspected in Failure to Thrive and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Propionylcarnitine

MeSH term MeSH ID Detail
Reperfusion Injury D015427 65 associated lipids
Body Weight D001835 333 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Amino Acid Metabolism, Inborn Errors D000592 16 associated lipids
Erectile Dysfunction D007172 19 associated lipids
Starvation D013217 47 associated lipids
Pregnancy Complications D011248 19 associated lipids
Penile Induration D010411 4 associated lipids
Total 10

PubChem Associated disorders and diseases

What pathways are associated with Propionylcarnitine

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with Propionylcarnitine?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with Propionylcarnitine?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with Propionylcarnitine?

There are no associated biomedical information in the current reference collection.

What genes are associated with Propionylcarnitine?

There are no associated biomedical information in the current reference collection.

What common seen animal models are associated with Propionylcarnitine?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with Propionylcarnitine

Download all related citations
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Authors Title Published Journal PubMed Link
Forny P et al. Novel Mouse Models of Methylmalonic Aciduria Recapitulate Phenotypic Traits with a Genetic Dosage Effect. 2016 J. Biol. Chem. pmid:27519416
Huemer M et al. Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines. 2015 J. Inherit. Metab. Dis. pmid:25762406
Guenzel AJ et al. Long-term sex-biased correction of circulating propionic acidemia disease markers by adeno-associated virus vectors. 2015 Hum. Gene Ther. pmid:25654275
Scioli MG et al. Propionyl-L-Carnitine Enhances Wound Healing and Counteracts Microvascular Endothelial Cell Dysfunction. 2015 PLoS ONE pmid:26473356
Tang YM et al. Urine and serum metabolomic profiling reveals that bile acids and carnitine may be potential biomarkers of primary biliary cirrhosis. 2015 Int. J. Mol. Med. pmid:26046127
Bogusiewicz A et al. In HepG2 cells, coexisting carnitine deficiency masks important indicators of marginal biotin deficiency. 2015 J. Nutr. pmid:25527659
Hailemariam D et al. Identification of predictive biomarkers of disease state in transition dairy cows. 2014 J. Dairy Sci. pmid:24630653
Ning WH and Zhao K Propionyl-L-carnitine induces eNOS activation and nitric oxide synthesis in endothelial cells via PI3 and Akt kinases. 2013 Sep-Oct Vascul. Pharmacol. pmid:23850990
Wu SN et al. [Analysis of propionylcarnitine in blood and methylmalonic acid in urine of 162 patients with methylmalonic acidemia]. 2013 Zhonghua Yi Xue Za Zhi pmid:23663331
Naccarato A et al. Identification and assay of underivatized urinary acylcarnitines by paper spray tandem mass spectrometry. 2013 Anal Bioanal Chem pmid:23907684
Huang Z et al. [Outcomes of patients with combined methylmalonic acidemia and homocystinuria after treatment]. 2013 Zhonghua Er Ke Za Zhi pmid:23751581
Huang Q et al. Metabolic characterization of hepatocellular carcinoma using nontargeted tissue metabolomics. 2013 Cancer Res. pmid:23824744
Brass EP et al. A systematic review and meta-analysis of propionyl-L-carnitine effects on exercise performance in patients with claudication. 2013 Vasc Med pmid:23321261
Pekkinen J et al. Betaine supplementation causes increase in carnitine metabolites in the muscle and liver of mice fed a high-fat diet as studied by nontargeted LC-MS metabolomics approach. 2013 Mol Nutr Food Res pmid:23868375
Luo T et al. A study on the efficacy and safety assessment of propionyl-L-carnitine tablets in treatment of intermittent claudication. 2013 Thromb. Res. pmid:23998557
Gianfrilli D et al. Propionyl-L-carnitine, L-arginine and niacin in sexual medicine: a nutraceutical approach to erectile dysfunction. 2012 Andrologia pmid:21966881
Malaguarnera M Carnitine derivatives: clinical usefulness. 2012 Curr. Opin. Gastroenterol. pmid:22333562
Kasahara M et al. Living-donor liver transplantation for propionic acidemia. 2012 Pediatr Transplant pmid:22151065
Morand R et al. Effect of short- and long-term treatment with valproate on carnitine homeostasis in humans. 2012 Ther Drug Monit pmid:22743351
Mingorance C et al. Propionyl-L-carnitine corrects metabolic and cardiovascular alterations in diet-induced obese mice and improves liver respiratory chain activity. 2012 PLoS ONE pmid:22457831