2-Monoolein

2-Monoolein is a lipid of Glycerolipids (GL) class. The involved functions are known as Regulation, Binding (Molecular Function), Cytokinesis of the fertilized ovum, Signal Transduction and Drug Interactions. 2-monoolein often locates in Extracellular, Brain region, Membrane, Body tissue and Protoplasm. The associated genes with 2-Monoolein are Glucagon-Like Peptide 1, Homologous Gene, LIPG gene and Serum Albumin. The related lipids are oleoylethanolamide, stearoylethanolamide, Fatty Acids, Nonesterified, Fatty Acids, Unsaturated and linoleoyl ethanolamide. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of 2-Monoolein, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2-Monoolein?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-Monoolein

PubChem Associated disorders and diseases

What pathways are associated with 2-Monoolein

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2-Monoolein?

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What functions are associated with 2-Monoolein?


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What lipids are associated with 2-Monoolein?

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What genes are associated with 2-Monoolein?

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What common seen animal models are associated with 2-Monoolein?

Knock-out

Knock-out are used in the study 'Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).' (Navia-Paldanius D et al., 2012).

Related references are published most in these journals:

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NCBI Entrez Crosslinks

All references with 2-Monoolein

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Authors Title Published Journal PubMed Link
pmid:
Ulloa NM and Deutsch DG Assessment of a spectrophotometric assay for monoacylglycerol lipase activity. 2010 AAPS J pmid:20186507
van Mechelen JB et al. Structures of mono-unsaturated triacylglycerols. V. The beta'(1)-2, beta'-3 and beta(2)-3 polymorphs of 1,3-dilauroyl-2-oleoylglycerol (LaOLa) from synchrotron and laboratory powder diffraction data. 2008 Acta Crystallogr., B pmid:19029706
Mandøe MJ et al. The 2-monoacylglycerol moiety of dietary fat appears to be responsible for the fat-induced release of GLP-1 in humans. 2015 Am. J. Clin. Nutr. pmid:26178726
Syed SK et al. Regulation of GPR119 receptor activity with endocannabinoid-like lipids. 2012 Am. J. Physiol. Endocrinol. Metab. pmid:23074242
Vandevoorde S et al. Influence of the degree of unsaturation of the acyl side chain upon the interaction of analogues of 1-arachidonoylglycerol with monoacylglycerol lipase and fatty acid amide hydrolase. 2005 Biochem. Biophys. Res. Commun. pmid:16181610
Gantayet A et al. Endocannabinoids and diacylglycerol kinase activity. 2011 Biochim. Biophys. Acta pmid:21194521
Hassing HA et al. Oral 2-oleyl glyceryl ether improves glucose tolerance in mice through the GPR119 receptor. 2016 Biofactors pmid:27297962
Kleberg K et al. Evaluation of the immediate vascular stability of lipoprotein lipase-generated 2-monoacylglycerol in mice. Biofactors pmid:25359532
Ghafouri N et al. Inhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2-arachidonoylglycerol. 2004 Br. J. Pharmacol. pmid:15492019