2-Monoolein

2-Monoolein is a lipid of Glycerolipids (GL) class. The involved functions are known as Regulation, Binding (Molecular Function), Cytokinesis of the fertilized ovum, Signal Transduction and Drug Interactions. 2-monoolein often locates in Extracellular, Brain region, Membrane, Body tissue and Protoplasm. The associated genes with 2-Monoolein are Glucagon-Like Peptide 1, Homologous Gene, LIPG gene and Serum Albumin. The related lipids are oleoylethanolamide, stearoylethanolamide, Fatty Acids, Nonesterified, Fatty Acids, Unsaturated and linoleoyl ethanolamide. The related experimental models are Knock-out.

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Introduction

To understand associated biological information of 2-Monoolein, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 2-Monoolein?

There are no associated biomedical information in the current reference collection.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 2-Monoolein

PubChem Associated disorders and diseases

What pathways are associated with 2-Monoolein

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 2-Monoolein?

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What functions are associated with 2-Monoolein?


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What lipids are associated with 2-Monoolein?

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What genes are associated with 2-Monoolein?

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What common seen animal models are associated with 2-Monoolein?

Knock-out

Knock-out are used in the study 'Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).' (Navia-Paldanius D et al., 2012).

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NCBI Entrez Crosslinks

All references with 2-Monoolein

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Authors Title Published Journal PubMed Link
pmid:
Ghafouri N et al. Inhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2-arachidonoylglycerol. 2004 Br. J. Pharmacol. pmid:15492019
Vandevoorde S et al. Influence of the degree of unsaturation of the acyl side chain upon the interaction of analogues of 1-arachidonoylglycerol with monoacylglycerol lipase and fatty acid amide hydrolase. 2005 Biochem. Biophys. Res. Commun. pmid:16181610
Vandevoorde S et al. Lack of selectivity of URB602 for 2-oleoylglycerol compared to anandamide hydrolysis in vitro. 2007 Br. J. Pharmacol. pmid:17143303
Rademacher DJ et al. Effects of acute and repeated restraint stress on endocannabinoid content in the amygdala, ventral striatum, and medial prefrontal cortex in mice. 2008 Neuropharmacology pmid:17675104
Cisneros JA et al. Structure-activity relationship of a series of inhibitors of monoacylglycerol hydrolysis--comparison with effects upon fatty acid amide hydrolase. 2007 J. Med. Chem. pmid:17764163
Nomura DK et al. Activation of the endocannabinoid system by organophosphorus nerve agents. 2008 Nat. Chem. Biol. pmid:18438404
van Mechelen JB et al. Structures of mono-unsaturated triacylglycerols. V. The beta'(1)-2, beta'-3 and beta(2)-3 polymorphs of 1,3-dilauroyl-2-oleoylglycerol (LaOLa) from synchrotron and laboratory powder diffraction data. 2008 Acta Crystallogr., B pmid:19029706
Greco R et al. Alterations of the endocannabinoid system in an animal model of migraine: evaluation in cerebral areas of rat. 2010 Cephalalgia pmid:19515121
Ulloa NM and Deutsch DG Assessment of a spectrophotometric assay for monoacylglycerol lipase activity. 2010 AAPS J pmid:20186507