| MeSH term | MeSH ID | Detail |
|---|---|---|
| Pain | D010146 | 64 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Thinness | D013851 | 11 associated lipids |
Total
3
2-Monoolein
2-Monoolein is a lipid of Glycerolipids (GL) class. The involved functions are known as Regulation, Binding (Molecular Function), Cytokinesis of the fertilized ovum, Signal Transduction and Drug Interactions. 2-monoolein often locates in Extracellular, Brain region, Membrane, Body tissue and Protoplasm. The associated genes with 2-Monoolein are Glucagon-Like Peptide 1, Homologous Gene, LIPG gene and Serum Albumin. The related lipids are oleoylethanolamide, stearoylethanolamide, Fatty Acids, Nonesterified, Fatty Acids, Unsaturated and linoleoyl ethanolamide. The related experimental models are Knock-out.
Cross Reference
Introduction
To understand associated biological information of 2-Monoolein, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 2-Monoolein?
There are no associated biomedical information in the current reference collection.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 2-Monoolein
PubChem Associated disorders and diseases
What pathways are associated with 2-Monoolein
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 2-Monoolein?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with 2-Monoolein?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with 2-Monoolein?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with 2-Monoolein?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with 2-Monoolein?
Knock-out
Knock-out are used in the study 'Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12).' (Navia-Paldanius D et al., 2012).
Related references are published most in these journals:
| Model | Cross reference | Weighted score | Related literatures |
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NCBI Entrez Crosslinks
All references with 2-Monoolein
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Martin GG et al. | Female Mice are Resistant to Fabp1 Gene Ablation-Induced Alterations in Brain Endocannabinoid Levels. | 2016 | Lipids | pmid:27450559 |
| Hassing HA et al. | Oral 2-oleyl glyceryl ether improves glucose tolerance in mice through the GPR119 receptor. | 2016 | Biofactors | pmid:27297962 |
| Murataeva N et al. | Where's my entourage? The curious case of 2-oleoylglycerol, 2-linolenoylglycerol, and 2-palmitoylglycerol. | 2016 | Pharmacol. Res. | pmid:27117667 |
| Hanlon EC et al. | Sleep Restriction Enhances the Daily Rhythm of Circulating Levels of Endocannabinoid 2-Arachidonoylglycerol. | 2016 | Sleep | pmid:26612385 |
| Mandøe MJ et al. | The 2-monoacylglycerol moiety of dietary fat appears to be responsible for the fat-induced release of GLP-1 in humans. | 2015 | Am. J. Clin. Nutr. | pmid:26178726 |
| Cheng YH et al. | Modulation of Glucagon-like Peptide-1 (GLP-1) Potency by Endocannabinoid-like Lipids Represents a Novel Mode of Regulating GLP-1 Receptor Signaling. | 2015 | J. Biol. Chem. | pmid:25903129 |
| Pastor A et al. | Analysis of ECs and related compounds in plasma: artifactual isomerization and ex vivo enzymatic generation of 2-MGs. | 2014 | J. Lipid Res. | pmid:24610889 |
| Koltyn KF et al. | Mechanisms of exercise-induced hypoalgesia. | 2014 | J Pain | pmid:25261342 |
| Roberts CJ et al. | Swim stress differentially affects limbic contents of 2-arachidonoylglycerol and 2-oleoylglycerol. | 2012 | Neuroscience | pmid:22192839 |
| Woodhams SG et al. | Spinal administration of the monoacylglycerol lipase inhibitor JZL184 produces robust inhibitory effects on nociceptive processing and the development of central sensitization in the rat. | 2012 | Br. J. Pharmacol. | pmid:22924700 |
| Syed SK et al. | Regulation of GPR119 receptor activity with endocannabinoid-like lipids. | 2012 | Am. J. Physiol. Endocrinol. Metab. | pmid:23074242 |
| Chicca A et al. | The antinociceptive triterpene β-amyrin inhibits 2-arachidonoylglycerol (2-AG) hydrolysis without directly targeting cannabinoid receptors. | 2012 | Br. J. Pharmacol. | pmid:22646533 |
| Navia-Paldanius D et al. | Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12). | 2012 | J. Lipid Res. | pmid:22969151 |
| Hansen KB et al. | 2-Oleoyl glycerol is a GPR119 agonist and signals GLP-1 release in humans. | 2011 | J. Clin. Endocrinol. Metab. | pmid:21778222 |
| Gantayet A et al. | Endocannabinoids and diacylglycerol kinase activity. | 2011 | Biochim. Biophys. Acta | pmid:21194521 |
| Björklund E et al. | Inhibition of monoacylglycerol lipase by troglitazone, N-arachidonoyl dopamine and the irreversible inhibitor JZL184: comparison of two different assays. | 2010 | Br. J. Pharmacol. | pmid:20735405 |
| Greco R et al. | Alterations of the endocannabinoid system in an animal model of migraine: evaluation in cerebral areas of rat. | 2010 | Cephalalgia | pmid:19515121 |
| Evagorou A et al. | Hydrolysis of 2-arachidonoylglycerol in Tetrahymena thermophila. Identification and partial characterization of a Monoacylglycerol Lipase-like enzyme. | 2010 | Eur. J. Protistol. | pmid:20889319 |
| Ulloa NM and Deutsch DG | Assessment of a spectrophotometric assay for monoacylglycerol lipase activity. | 2010 | AAPS J | pmid:20186507 |
| Nomura DK et al. | Activation of the endocannabinoid system by organophosphorus nerve agents. | 2008 | Nat. Chem. Biol. | pmid:18438404 |