Disease MeSH term: Kidney Failure, Chronic

Possible associated with:

Structure name description Reference count
acetic acid acetic acid is a lipid of Fatty Acyls (FA) class. Acetic acid is associated with abnormalities such as Vitamin B 12 Deficiency. The involved functions are known as Excretory function. The related lipids are Propionate. 89633
butyric acid butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid. 9358
stearic acid stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out. 5692
3-Methyl-2-oxobutanoic acid 3-Methyl-2-oxobutanoic acid is a lipid of Fatty Acyls (FA) class. 3-methyl-2-oxobutanoic acid is associated with abnormalities such as Maple Syrup Urine Disease and Kidney Failure, Chronic. The involved functions are known as Phosphorylation, Citric Acid Cycle, inhibitors, Process and Metabolic Control. 3-methyl-2-oxobutanoic acid often locates in Mitochondria, BL21, Cytoplasm, Ribosomes and Head. The associated genes with 3-Methyl-2-oxobutanoic acid are Genome, Homologous Gene, Operon, Alleles and Oxidoreductase Gene. The related lipids are dimyristoylphosphatidylglycerol, 9-oxononanoic acid, Valerates and alpha-ketocaproic acid. 1021
Arachidonic acid Arachidonic acid is a lipid of Fatty Acyls (FA) class. Arachidonic acid is associated with abnormalities such as Atherosclerosis, Ischemia, Hypertensive disease, Hypertension induced by pregnancy and Vascular ring of aorta. The involved functions are known as Platelet aggregation, Anabolism, Ion Transport, Signal Transduction Pathways and Signal. Arachidonic acid often locates in Extracellular, Body tissue, Protoplasm, Tissue membrane and soluble. The associated genes with Arachidonic acid are CYP2J2 gene, CYP2E1 gene, Recombinant Proteins, POR gene and P4HTM gene. The related lipids are Fatty Acids, Glycerophospholipids, Steroids, octadecadienoic acid and 9-hydroxy-10,12-octadecadienoic acid. The related experimental models are Mouse Model and Knock-out. 22864
cis-9-palmitoleic acid Cis-9-palmitoleic acid is a lipid of Fatty Acyls (FA) class. 694
Linoelaidic acid Linoelaidic acid is a lipid of Fatty Acyls (FA) class. Linoelaidic acid is associated with abnormalities such as Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Pneumonia, Chronic Obstructive Airway Disease and Metabolic syndrome. The involved functions are known as Metabolic Inhibition, Steroid biosynthesis, Signal Transduction, Insulin Resistance and Inflammation. Linoelaidic acid often locates in Mitochondria, Membrane and Cytoplasmic matrix. The associated genes with Linoelaidic acid are FFAR1 gene, C9orf7 gene, TNF gene, CCL2 gene and TLR4 gene. The related lipids are Fatty Acids, octadecadienoic acid, Steroids, methyl linoleate and Cyanoketone. 10058
gamma-Linolenic acid Gamma-linolenic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Drug Interactions. Gamma-linolenic acid often locates in Articular system. 1919
4,7,10,13,16-docosapentaenoic acid 4,7,10,13,16-docosapentaenoic acid is a lipid of Fatty Acyls (FA) class. 546
7,10,13,16,19-docosapentaenoic acid 7,10,13,16,19-docosapentaenoic acid is a lipid of Fatty Acyls (FA) class. 385
Clupanodonic acid Clupanodonic acid is a lipid of Fatty Acyls (FA) class. 385
Osbond acid Osbond acid is a lipid of Fatty Acyls (FA) class. 383
DHA Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental. 11054
7-octadecynoic acid 7-octadecynoic acid is a lipid of Fatty Acyls (FA) class. 8379
EPA Epa is a lipid of Fatty Acyls (FA) class. 5952
Ethyl icosapentate Ethyl icosapentate is a lipid of Fatty Acyls (FA) class. 28
12-hydroxy-5,8,10-heptadecatrienoic acid 12-hydroxy-5,8,10-heptadecatrienoic acid is a lipid of Fatty Acyls (FA) class. 196
3-hydroxybutyric acid 3-hydroxybutyric acid is a lipid of Fatty Acyls (FA) class. 3-hydroxybutyric acid is associated with abnormalities such as Ketosis. The involved functions are known as fatty acid oxidation, Oxidation, Synthesis, inhibitors and glucose metabolism. 3-hydroxybutyric acid often locates in Blood, Adipose tissue, Protoplasm, Hepatic and Extracellular. The associated genes with 3-hydroxybutyric acid are Genes, Developmental and Oncogene, RET. The related lipids are Fatty Acids, Nonesterified, 6-hydroxyhexanoate, tributyrin, 3-Hydroxyvalerate and Valerates. 4735
(r)-3-hydroxybutanoic acid (r)-3-hydroxybutanoic acid is a lipid of Fatty Acyls (FA) class. 2710
diketo-gulonic acid Diketo-gulonic acid is a lipid of Fatty Acyls (FA) class. 104
Iodoacetic acid Iodoacetic acid is a lipid of Fatty Acyls (FA) class. Iodoacetic acid is associated with abnormalities such as Photoreceptor degeneration and Post MI. The involved functions are known as Hypoxia, Glycolysis, Metabolic Inhibition, Oxidation and PTPS activity. Iodoacetic acid often locates in Extracellular, Muscle, Mitochondria, Cytoplasmic matrix and Tissue membrane. The associated genes with Iodoacetic acid are SLC33A1 gene, GTF2I gene, Mutant Proteins, TRIM33 gene and oxytocin, 1-desamino-(O-Et-Tyr)(2)-. 3688
4-aminobutyric acid 4-aminobutyric acid is a lipid of Fatty Acyls (FA) class. 4-aminobutyric acid is associated with abnormalities such as Epilepsy and Premenstrual syndrome. The involved functions are known as Binding (Molecular Function), neuron survival, Process, Uptake and physiological aspects. 4-aminobutyric acid often locates in Microglial, Neurofilament, Neuraxis, Brain region and Neurites. The associated genes with 4-aminobutyric acid are arginine methyl ester, SLC33A1 gene, NKS1 gene, P4HTM gene and ITSN2 gene. The related lipids are pregnenolone sulfate, pregnane-20-one, Pregnanes, Steroids and endogenous steroids. 19702
L-norleucine L-norleucine is a lipid of Fatty Acyls (FA) class. L-norleucine is associated with abnormalities such as Neonatal maladjustment syndrome, Virus Diseases, Kidney Failure, Chronic, Infection and Acquired Immunodeficiency Syndrome. The involved functions are known as Proteolysis, Metabolic Inhibition, Oxidation, immunoreactivity and Sterility. L-norleucine often locates in Blood, Body tissue, Membrane, Protoplasm and Adipose tissue. The associated genes with L-norleucine are N(6)-carboxymethyllysine, P4HTM gene, Polypeptides, EIF3K gene and aminoacid analog. The related lipids are Liposomes and Membrane Lipids. 2389
3-amino-isobutanoic acid 3-amino-isobutanoic acid is a lipid of Fatty Acyls (FA) class. 384
2,5-diaminopentanoic acid 2,5-diaminopentanoic acid is a lipid of Fatty Acyls (FA) class. The involved functions are known as Vasodilation, Intestinal Absorption and Pinocytosis. 2,5-diaminopentanoic acid often locates in Mitochondria, Microfilaments, NADH dehydrogenase complex and respiratory chain complex III location sensu Eukarya. The associated genes with 2,5-diaminopentanoic acid are GAPDH gene and iberiotoxin. 8868
Lipoic acid Lipoic acid is a lipid of Fatty Acyls (FA) class. 7940
Cmpf Cmpf is a lipid of Fatty Acyls (FA) class. 132
Glucaric acid Glucaric acid is a lipid of Fatty Acyls (FA) class. Glucaric acid is associated with abnormalities such as Consumption-archaic term for TB and furuncle. The involved functions are known as Oxidation, Mutation, Process, Cell Growth and Anabolism. Glucaric acid often locates in BL21, Clone and host. The associated genes with Glucaric acid are MIOX gene, ISYNA1 gene, Genome and Candidate Disease Gene. The related experimental models are Knock-out. 1814
Methylmalonic acid Methylmalonic acid is a lipid of Fatty Acyls (FA) class. Methylmalonic acid is associated with abnormalities such as Vitamin B 12 Deficiency, Osteoporosis, Anemia, Anemia, Megaloblastic and Renal impairment. The involved functions are known as Abnormal renal function, Lactation, physiological aspects, phosphoglycerate dehydrogenase activity and Excretory function. Methylmalonic acid often locates in Entire bony skeleton, Blood, Protoplasm, Muscle and Body tissue. The associated genes with Methylmalonic acid are IMPACT gene, ACSF3 gene, CBLC gene, MMADHC gene and LMBRD1 gene. The related lipids are Fatty Acids and Butanols. 3174
Oxalacetic acid Oxalacetic acid is a lipid of Fatty Acyls (FA) class. 3226
Prostaglandin E2 Prostaglandin E2 is a lipid of Fatty Acyls (FA) class. Prostaglandin e2 is associated with abnormalities such as Renal glomerular disease, Arthritis, Degenerative polyarthritis, Pancreatitis and Rheumatoid Arthritis. The involved functions are known as enzyme pathway, Atherogenesis, Anabolism, inhibitors and Oxidants. Prostaglandin e2 often locates in Tissue membrane, Blood, Extracellular, Membrane and Protoplasm. The associated genes with Prostaglandin E2 are PTGS2 gene, TP53 gene, TNFRSF5 gene, FASTK Gene and TNF gene. The related lipids are Lipopolysaccharides, Steroids, monooxyethylene trimethylolpropane tristearate, Fatty Acids, Unsaturated and Promega. The related experimental models are Arthritis, Adjuvant-Induced, Xenograft Model, Experimental Autoimmune Encephalomyelitis, Cancer Model and Knock-out. 49278
PGD2 Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model. 6464
PGH2 Pgh2 is a lipid of Fatty Acyls (FA) class. The involved functions are known as peroxidase activity, Synthesis and prostaglandin biosynthesis. Pgh2 often locates in Skeletal system. The associated genes with PGH2 are Homologous Gene. 701
11beta-PGF2 11beta-pgf2 is a lipid of Fatty Acyls (FA) class. 15009
Leukotriene b4 Leukotriene b4 is a lipid of Fatty Acyls (FA) class. The involved functions are known as Chemotaxis, release of sequestered calcium ion into cytoplasm and Polymerization. Leukotriene b4 often locates in Protoplasm. The associated genes with Leukotriene b4 are phallacidin. 9311
Thromboxane b2 Thromboxane b2 is a lipid of Fatty Acyls (FA) class. Thromboxane b2 is associated with abnormalities such as endothelial dysfunction, Diabetes Mellitus, Non-Insulin-Dependent, Diabetes Mellitus, Ischemia and Thrombocytosis. The involved functions are known as Platelet Activation, Excretory function, Anabolism, Inflammation and mRNA Expression. Thromboxane b2 often locates in Endothelium, Hepatic and Microsomes, Liver. The associated genes with Thromboxane b2 are PTGS2 gene, prothrombin fragment 2 and CCL14 wt Allele. 10175
6-keto-pgf1alpha 6-keto-pgf1alpha is a lipid of Fatty Acyls (FA) class. 3430
1-propanol 1-propanol is a lipid of Fatty Acyls (FA) class. 6697
Scillarenin 3-o-rhamnoside Scillarenin 3-o-rhamnoside is a lipid of Sterol Lipids (ST) class. 74
Trans-2-nonenal Trans-2-nonenal is a lipid of Fatty Acyls (FA) class. 129
4-hydroxynonenal 4-hydroxynonenal is a lipid of Fatty Acyls (FA) class. 4-hydroxynonenal is associated with abnormalities such as Chronic disease, Obesity, Diabetes, Acquired Immunodeficiency Syndrome and Lung diseases. The involved functions are known as protein expression, Glycolysis, mRNA Expression, Regulation and Mitochondrion in division. 4-hydroxynonenal often locates in Muscle, Mitochondria, Adipose tissue, Head and Mouse Muscle. The associated genes with 4-hydroxynonenal are STAT3 gene, SIRT1 gene, PGC gene, IL6 gene and cytochrome c''. The related lipids are Lipopolysaccharides, Lipid Peroxides, Promega, Membrane Lipids and oxidized lipid. The related experimental models are Mouse Model, Knock-out, Transgenic Model, Disease model and Rodent Model. 5685
O-propanoylcarnitine O-propanoylcarnitine is a lipid of Fatty Acyls (FA) class. 258
Hexane Hexane is a lipid of Fatty Acyls (FA) class. 9183
Acetoin Acetoin is a lipid of Fatty Acyls (FA) class. The involved functions are known as glucose metabolism, glucose catabolic process to lactate via pyruvate, Biochemical Pathway, Catabolite Repression and Regulation. Acetoin often locates in Chromosomes, Protoplasm, Cytoplasmic matrix, Cytoplasm and Extracellular. The associated genes with Acetoin are resistance genes, Homologous Gene, BDH1 gene, Genome and Operon. The related lipids are Butyric Acid. 1216
Platelet activating factor Platelet activating factor is a lipid of Glycerophospholipids (GP) class. Platelet activating factor is associated with abnormalities such as Atherosclerosis, Acute cholecystitis without calculus, Cholecystitis, Colitis and Cholecystitis, Acute. The involved functions are known as Cell Survival, Metabolic Inhibition, lipid oxidation, Apoptosis and Oxidation. Platelet activating factor often locates in soluble, Cellular Membrane, Smooth muscle (tissue), Intima and Tissue specimen. The associated genes with Platelet activating factor are apolipoprotein A-I Milano, Homologous Gene, TSPO gene, HBEGF gene and SLC33A1 gene. The related lipids are Hydroxycholesterols, Liposomes, 25-hydroxycholesterol, Lysophosphatidylcholines and Lipopolysaccharides. The related experimental models are Knock-out, Mouse Model and Transgenic Model. 7383
tacrolimus Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene. 12730
erythromycin erythromycin is a lipid of Polyketides (PK) class. Erythromycin is associated with abnormalities such as Systemic Inflammatory Response Syndrome, Pneumonia, Infection, Pneumococcal Infections and Exanthema. The involved functions are known as Pharmacodynamics, Sterility, Agent, Drug Kinetics and Adjudication. Erythromycin often locates in Blood, peritoneal, Extracellular, Ribosomes and apicoplast. The associated genes with erythromycin are P4HTM gene, SLC33A1 gene, FAM3B gene, Operon and Homologous Gene. The related lipids are Hydroxytestosterones, Steroids, Propionate, Mycolic Acids and campesterol. The related experimental models are Mouse Model and Knock-out. 19871
doxorubicin Adriamycin is a lipid of Polyketides (PK) class. Adriamycin is associated with abnormalities such as Cardiomyopathies. The involved functions are known as Transcription, Genetic, Process, Drug effect disorder, Diastasis and Oxidation-Reduction. Adriamycin often locates in Muscle, Myocardium and Entire gastrointestinal tract. 54913
phorbol 13-acetate 12-myristate Phorbol 13-acetate 12-myristate is a lipid of Prenol Lipids (PR) class. The involved functions are known as DNA Fragmentation, Phosphorylation and Irritation. Phorbol 13-acetate 12-myristate often locates in low-density lipoprotein particle. The associated genes with phorbol 13-acetate 12-myristate are FPR1 gene and ABCB1 gene. 40921
cholesterol cholesterol is a lipid of Sterol Lipids (ST) class. Cholesterol is associated with abnormalities such as Trypanosomiasis, Chagas Disease, Cleft Palate, Chondrodysplasia punctata 2, X-linked dominant and Child syndrome. The involved functions are known as Blood Circulation, Sterol Biosynthesis Pathway, Receptor Mediated Endocytosis, Methylation and Signal. Cholesterol often locates in Animal tissue, Blood, Membrane, Plasma membrane and peroxisome. The associated genes with cholesterol are MBD2 gene, SIM, SLC33A1 gene, Genome and NSDHL gene. The related lipids are Sterols, zymosterol, fecosterol, Total cholesterol and 7-dehydrocholesterol. The related experimental models are Mouse Model, Knock-out, Genetically Engineered Mouse and Disease model. 98461
Aldosterone Aldosterone is a lipid of Sterol Lipids (ST) class. Aldosterone is associated with abnormalities such as Hypertensive disease, Cardiovascular Diseases, endothelial dysfunction, Myocardial Infarction and Kidney Diseases. The involved functions are known as physiological aspects, Regulation, Gene Expression, Hypertrophy and Inflammation. Aldosterone often locates in Renal Tissue, Renin-Angiotensin-Aldosterone System, Body tissue, Protoplasm and Epithelium. The associated genes with Aldosterone are TSC22D3 gene, Candidate Disease Gene, SGK1 gene, Operator gene and ATP1A1 gene. The related lipids are Steroids. The related experimental models are Mouse Model. 17633
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