Lipoxin b

Lipoxin b is a lipid of Fatty Acyls (FA) class.

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There are no associated biomedical information in the current reference collection.

Current reference collection contains 415 references associated with Lipoxin b in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for Lipoxin b

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with Lipoxin b

MeSH term MeSH ID Detail
Inflammation D007249 119 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Asthma D001249 52 associated lipids
Leukemia, Myelogenous, Chronic, BCR-ABL Positive D015464 17 associated lipids
Nasal Polyps D009298 26 associated lipids
Total 5

All references with Lipoxin b

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Authors Title Published Journal PubMed Link
Karra L et al. Lipoxin Bâ‚„ promotes the resolution of allergic inflammation in the upper and lower airways of mice. 2015 Mucosal Immunol pmid:25465102
O'Sullivan TP et al. Aromatic lipoxin A4 and lipoxin B4 analogues display potent biological activities. 2007 J. Med. Chem. pmid:17960922
Parkinson JF Lipoxin and synthetic lipoxin analogs: an overview of anti-inflammatory functions and new concepts in immunomodulation. 2006 Inflamm Allergy Drug Targets pmid:16613568
Serhan CN Lipoxins and aspirin-triggered 15-epi-lipoxins are the first lipid mediators of endogenous anti-inflammation and resolution. 2005 Sep-Oct Prostaglandins Leukot. Essent. Fatty Acids pmid:16005201
Ariel A et al. Aspirin-triggered lipoxin A4 and B4 analogs block extracellular signal-regulated kinase-dependent TNF-alpha secretion from human T cells. 2003 J. Immunol. pmid:12794159
Goh J et al. Lipoxins: pro-resolution lipid mediators in intestinal inflammation. 2003 Gastroenterology pmid:12671901
Bonnans C et al. Lipoxins are potential endogenous antiinflammatory mediators in asthma. 2002 Am. J. Respir. Crit. Care Med. pmid:12045128
Stenson C et al. Biphasic regulation of leukocyte trafficking by lipoxins. 2002 Adv. Exp. Med. Biol. pmid:12664638
Serhan CN Lipoxins and aspirin-triggered 15-epi-lipoxins are endogenous components of antiinflammation: emergence of the counterregulatory side. 2001 Arch. Immunol. Ther. Exp. (Warsz.) pmid:11478391
McMahon B et al. Lipoxins: revelations on resolution. 2001 Trends Pharmacol. Sci. pmid:11478982
Tornhamre S et al. 15-Lipoxygenation of leukotriene A(4). Studies Of 12- and 15-lipoxygenase efficiency to catalyze lipoxin formation. 2000 Biochim. Biophys. Acta pmid:10760478
Desplat V et al. Effects of lipoxygenase metabolites of arachidonic acid on the growth of human blood CD34(+) progenitors. 2000 Blood Cells Mol. Dis. pmid:11112380
Serhan CN et al. Lipoxins, aspirin-triggered 15-epi-lipoxin stable analogs and their receptors in anti-inflammation: a window for therapeutic opportunity. 2000 Ernst Schering Res. Found. Workshop pmid:10943332
Sanak M et al. Aspirin-tolerant asthmatics generate more lipoxins than aspirin-intolerant asthmatics. 2000 Eur. Respir. J. pmid:10933083
Denizot Y et al. Effect of cytokines and lipid mediators on the synthesis of interleukin 1 beta by human bone marrow stromal cells. 2000 Cytokine pmid:10857767
Kikuta Y et al. Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14. 2000 Arch. Biochem. Biophys. pmid:11185557
Desplat V et al. Incorporation and effect of arachidonic acid on the growth of human myeloma cell lines. 1999 Mediators Inflamm. pmid:10704149
Serhan CN et al. Aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogs inhibit neutrophil-mediated changes in vascular permeability. 1999 Adv. Exp. Med. Biol. pmid:10667343
Takano T et al. Neutrophil-mediated changes in vascular permeability are inhibited by topical application of aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogues. 1998 J. Clin. Invest. pmid:9466977
Maddox JF et al. Lipoxin B4 regulates human monocyte/neutrophil adherence and motility: design of stable lipoxin B4 analogs with increased biologic activity. 1998 FASEB J. pmid:9535221
Serhan CN Lipoxin metabolism by human promyelocytic leukemia (HL-60) cells. 1997 Adv. Exp. Med. Biol. pmid:9547615
Tang DG et al. Arachidonate lipoxygenases as essential regulators of cell survival and apoptosis. 1996 Proc. Natl. Acad. Sci. U.S.A. pmid:8643560
Romano M et al. Activation of human monocytes and the acute monocytic leukemia cell line (THP-1) by lipoxins involves unique signaling pathways for lipoxin A4 versus lipoxin B4: evidence for differential Ca2+ mobilization. 1996 J. Immunol. pmid:8757340
Papayianni A et al. Lipoxin A4 and B4 inhibit leukotriene-stimulated interactions of human neutrophils and endothelial cells. 1996 J. Immunol. pmid:8690917
Wu SH [Progress in the study of lipoxin and leukotriene]. 1996 Sheng Li Ke Xue Jin Zhan pmid:8731993
Maddox JF and Serhan CN Lipoxin A4 and B4 are potent stimuli for human monocyte migration and adhesion: selective inactivation by dehydrogenation and reduction. 1996 J. Exp. Med. pmid:8551217
Bratt J et al. Mechanisms for lipoxin A4 induced neutrophil dependent cytotoxicity for human endothelial cells. 1995 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:7732886
Serhan CN and Romano M Lipoxin biosynthesis and actions: role of the human platelet LX-synthase. 1995 J Lipid Mediat Cell Signal pmid:8777573
Tamaoki J et al. Lipoxin A4 inhibits cholinergic neurotransmission through nitric oxide generation in the rabbit trachea. 1995 Eur. J. Pharmacol. pmid:8991795
Sri Kantha S et al. Effects of prostaglandin D2, lipoxins and leukotrienes on sleep and brain temperature of rats. 1994 Prostaglandins Leukot. Essent. Fatty Acids pmid:7972271
Mizukami Y et al. omega-Oxidation of lipoxin B4 by rat liver. Identification of an omega-carboxy metabolite of lipoxin B4. 1994 Eur. J. Biochem. pmid:7925420
Edenius C et al. Stimulation of lipoxin synthesis from leukotriene A4 by endogenously formed 12-hydroperoxyeicosatetraenoic acid in activated human platelets. 1994 Biochim. Biophys. Acta pmid:8305492
Lindgren JA et al. Formation and effects of leukotrienes and lipoxins in human bone marrow. 1993 Mar-Apr J Lipid Mediat pmid:8357990
Levy BD et al. Human alveolar macrophages have 15-lipoxygenase and generate 15(S)-hydroxy-5,8,11-cis-13-trans-eicosatetraenoic acid and lipoxins. 1993 J. Clin. Invest. pmid:8376607
Lerner R et al. Lipoxin A4 induces hyperadhesiveness in human endothelial cells for neutrophils. 1993 Blood pmid:8393356
Stajszczyk M and Gmiński J [Lipoxins--new arachidonic acid-derived molecules]. 1993 Postepy Hig Med Dosw pmid:8415322
Mizukami Y et al. Omega-hydroxylation of lipoxin B4 by human neutrophil microsomes: identification of omega-hydroxy metabolite of lipoxin B4 and catalysis by leukotriene B4 omega-hydroxylase (cytochrome P-450LTB omega). 1993 Biochim. Biophys. Acta pmid:8389204
Romano M et al. Lipoxin synthase activity of human platelet 12-lipoxygenase. 1993 Biochem. J. pmid:8250832
Conti P et al. Role of lipoxins A4 and B4 in the generation of arachidonic acid metabolites by rat mast cells and their effect on [3H]serotonin release. 1992 Immunol. Lett. pmid:1612634
Uski TK and Högestätt ED Effects of various cyclooxygenase and lipoxygenase metabolites on guinea-pig cerebral arteries. 1992 Gen. Pharmacol. pmid:1592217
Hoedemaker M et al. Influence of arachidonic acid metabolites and steroids on function of bovine polymorphonuclear neutrophils. 1992 Am. J. Vet. Res. pmid:1329587
Chavis C et al. Formation of lipoxins and leukotrienes by human alveolar macrophages incubated with 15(S)-HETE: a model for cellular cooperation between macrophages and airway epithelial cells. 1992 Eicosanoids pmid:1337977
Romano M and Serhan CN Lipoxin generation by permeabilized human platelets. 1992 Biochemistry pmid:1381961
Beckman BS et al. Actions of lipoxins A4 and B4 on signal transduction events in Friend erythroleukemia cells. 1992 Proc. Soc. Exp. Biol. Med. pmid:1409732
Hu L and Hou WM [Biosynthesis and biological activities of lipoxins]. 1992 Sheng Li Ke Xue Jin Zhan pmid:1411429
Katoh T et al. Renal hemodynamic actions of lipoxins in rats: a comparative physiological study. 1992 Am. J. Physiol. pmid:1415572
Lindgren JA et al. Conversion of leukotriene A4 to lipoxins by human nasal polyps and bronchial tissue. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1847787
Edenius C et al. Lipoxin formation in human platelets. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1847789
Stenke L et al. Lipoxygenase products in myeloproliferative disorders: increased leukotriene C4 and decreased lipoxin formation in chronic myeloid leukemia. 1991 Adv. Prostaglandin Thromboxane Leukot. Res. pmid:1825431
Boucher JL et al. Metabolism of lipoxins A4 and B4 and of their all-trans isomers by human leukocytes and rat liver microsomes. 1991 Biochem. Biophys. Res. Commun. pmid:2043100

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