EPA

Epa is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 19347 references associated with EPA in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for EPA

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with EPA

MeSH term MeSH ID Detail
Pancreatic Neoplasms D010190 77 associated lipids
Inflammation D007249 119 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Fatty Liver D005234 48 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Per page 10 20 50 100 | Total 140

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with EPA

Download all related citations
Per page 10 20 50 100 | Total 4880
Authors Title Published Journal PubMed Link
Childs CE et al. Increased dietary α-linolenic acid has sex-specific effects upon eicosapentaenoic acid status in humans: re-examination of data from a randomised, placebo-controlled, parallel study. 2014 Nutr J pmid:25496415
Liu J and Ma DW The role of n-3 polyunsaturated fatty acids in the prevention and treatment of breast cancer. 2014 Nutrients pmid:25412153
Fernández-González R et al. Decontamination solutions for polychlorinated biphenyls (PCBs) in raw fish oils from environmentally contaminated sea fishes. 2014 Sci. Total Environ. pmid:24095964
Huang X et al. Serum and adipose tissue fatty acid composition as biomarkers of habitual dietary fat intake in elderly men with chronic kidney disease. 2014 Nephrol. Dial. Transplant. pmid:23229929
Wang S et al. Lipid content in hepatic and gonadal adipose tissue parallel aortic cholesterol accumulation in mice fed diets with different omega-6 PUFA to EPA plus DHA ratios. 2014 Clin Nutr pmid:23672804
De Mel D and Suphioglu C Fishy business: effect of omega-3 fatty acids on zinc transporters and free zinc availability in human neuronal cells. 2014 Nutrients pmid:25195602
Browning LM et al. Compared with daily, weekly n-3 PUFA intake affects the incorporation of eicosapentaenoic acid and docosahexaenoic acid into platelets and mononuclear cells in humans. 2014 J. Nutr. pmid:24647395
Bremer AA et al. Fish oil supplementation ameliorates fructose-induced hypertriglyceridemia and insulin resistance in adult male rhesus macaques. 2014 J. Nutr. pmid:24108131
Rodrigues PO et al. Influence of feeding graded levels of canned sardines on the inflammatory markers and tissue fatty acid composition of Wistar rats. 2014 Br. J. Nutr. pmid:24775714
Wu FJ et al. The protective effect of eicosapentaenoic acid-enriched phospholipids from sea cucumber Cucumaria frondosa on oxidative stress in PC12 cells and SAMP8 mice. 2014 Neurochem. Int. pmid:24231470
D'Angelo L et al. A combination of eicosapentaenoic acid-free fatty acid, epigallocatechin-3-gallate and proanthocyanidins has a strong effect on mTOR signaling in colorectal cancer cells. 2014 Carcinogenesis pmid:25123131
Lee CH et al. Eicosapentaenoic acid protects against palmitic acid-induced endothelial dysfunction via activation of the AMPK/eNOS pathway. 2014 Int J Mol Sci pmid:24918290
Serikawa T et al. Ratio of eicosapentaenoic acid to arachidonic acid is a critical risk factor for acute coronary syndrome in middle-aged older patients as well as younger adult patients. 2014 J Cardiol pmid:23993904
Pérez-López P et al. Environmental evaluation of eicosapentaenoic acid production by Phaeodactylum tricornutum. 2014 Sci. Total Environ. pmid:23994733
Scarparo RK et al. Intracanal delivery of Resolvin E1 controls inflammation in necrotic immature rat teeth. 2014 J Endod pmid:24767563
Kubota T et al. Eicosapentaenoic acid is converted via ω-3 epoxygenation to the anti-inflammatory metabolite 12-hydroxy-17,18-epoxyeicosatetraenoic acid. 2014 FASEB J. pmid:24128889
Purushothaman D et al. Flaxseed oil supplementation alters the expression of inflammatory-related genes in dogs. 2014 Genet. Mol. Res. pmid:25078588
Shao Z et al. Cytochrome P450 2C8 ω3-long-chain polyunsaturated fatty acid metabolites increase mouse retinal pathologic neovascularization--brief report. 2014 Arterioscler. Thromb. Vasc. Biol. pmid:24458713
Santos S et al. Fatty acids derived from a food frequency questionnaire and measured in the erythrocyte membrane in relation to adiponectin and leptin concentrations. 2014 Eur J Clin Nutr pmid:24642786
Camacho-Rodríguez J et al. A quantitative study of eicosapentaenoic acid (EPA) production by Nannochloropsis gaditana for aquaculture as a function of dilution rate, temperature and average irradiance. 2014 Appl. Microbiol. Biotechnol. pmid:24318007
Abiusi F et al. Growth, photosynthetic efficiency, and biochemical composition of Tetraselmis suecica F&M-M33 grown with LEDs of different colors. 2014 Biotechnol. Bioeng. pmid:23904253
Zhao M and Chen X Eicosapentaenoic acid promotes thermogenic and fatty acid storage capacity in mouse subcutaneous adipocytes. 2014 Biochem. Biophys. Res. Commun. pmid:25017914
Yuan D et al. Ancestral genetic complexity of arachidonic acid metabolism in Metazoa. 2014 Biochim. Biophys. Acta pmid:24801744
Fukuoka Y et al. Effects of a fish-based diet and administration of pure eicosapentaenoic acid on brachial-ankle pulse wave velocity in patients with cardiovascular risk factors. 2014 J Cardiol pmid:24080436
Piazzi G et al. Eicosapentaenoic acid free fatty acid prevents and suppresses colonic neoplasia in colitis-associated colorectal cancer acting on Notch signaling and gut microbiota. 2014 Int. J. Cancer pmid:24676631
Sorensen LS et al. Effects of perioperative supplementation with omega-3 fatty acids on leukotriene Bâ‚„ and leukotriene Bâ‚… production by stimulated neutrophils in patients with colorectal cancer: a randomized, placebo-controlled intervention trial. 2014 Nutrients pmid:25268838
Shaikh NA et al. Efficacy of a unique omega-3 formulation on the correction of nutritional deficiency and its effects on cardiovascular disease risk factors in a randomized controlled VASCAZEN(®) REVEAL Trial. 2014 Mol. Cell. Biochem. pmid:25185754
Gregory MK and James MJ Functional characterization of the duck and turkey fatty acyl elongase enzymes ELOVL5 and ELOVL2. 2014 J. Nutr. pmid:24919687
O'Connor-Robison CI et al. The impact of dietary long-chain polyunsaturated fatty acids on bone and cartilage in gilts and sows. 2014 J. Anim. Sci. pmid:25184850
Norris JM et al. Erythrocyte membrane docosapentaenoic acid levels are associated with islet autoimmunity: the Diabetes Autoimmunity Study in the Young. 2014 Diabetologia pmid:24240437
Flesher RP et al. Resolvin E1 promotes resolution of inflammation in a mouse model of an acute exacerbation of allergic asthma. 2014 Clin. Sci. pmid:24344649
Dai XW et al. Erythrocyte membrane n-3 fatty acid levels and carotid atherosclerosis in Chinese men and women. 2014 Atherosclerosis pmid:24401220
Aursnes M et al. Total synthesis of the lipid mediator PD1n-3 DPA: configurational assignments and anti-inflammatory and pro-resolving actions. 2014 J. Nat. Prod. pmid:24576195
Ghasemi Fard S et al. Comparison of the bioavailability of docosapentaenoic acid (DPA, 22:5n-3) and eicosapentaenoic acid (EPA, 20:5n-3) in the rat. 2014 Prostaglandins Leukot. Essent. Fatty Acids pmid:24238887
Petrie JR et al. Metabolic engineering Camelina sativa with fish oil-like levels of DHA. 2014 PLoS ONE pmid:24465476
Sengupta A and Ghosh M Effect of sterol esters on lipid composition and antioxidant status of erythrocyte membrane of hypercholesterolemic rats. 2014 J Oleo Sci pmid:24770475
Hiatt WR and Smith RJ Assessing the clinical benefits of lipid-disorder drugs. 2014 N. Engl. J. Med. pmid:24476429
Gyurko R and Van Dyke TE The role of polyunsaturated ω-3 fatty acid eicosapentaenoic acid-derived resolvin E1 (RvE1) in bone preservation. 2014 Crit. Rev. Immunol. pmid:24941160
Yang P et al. Prostaglandin E3 metabolism and cancer. 2014 Cancer Lett. pmid:24657656
Koppenol A et al. Effect of the ratio of dietary n-3 fatty acids eicosapentaenoic acid and docosahexaenoic acid on broiler breeder performance, egg quality, and yolk fatty acid composition at different breeder ages. 2014 Poult. Sci. pmid:24604849
Ceccarelli V et al. Eicosapentaenoic acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. 2014 PLoS ONE pmid:24454781
Li X et al. Production of structured phosphatidylcholine with high content of DHA/EPA by immobilized phospholipase A₁-catalyzed transesterification. 2014 Int J Mol Sci pmid:25170810
Adarme-Vega TC et al. Towards sustainable sources for omega-3 fatty acids production. 2014 Curr. Opin. Biotechnol. pmid:24607804
Pottala JV et al. Higher RBC EPA + DHA corresponds with larger total brain and hippocampal volumes: WHIMS-MRI study. 2014 Neurology pmid:24453077
Jin M et al. Eicosapentaenoic acid and docosahexaenoic acid suppress Th2 cytokine expression in RBL-2H3 basophilic leukemia cells. 2014 J Med Food pmid:24460246
Chen MY et al. Quantitative risk-benefit analysis of fish consumption for women of child-bearing age in Hong Kong. 2014 Food Addit Contam Part A Chem Anal Control Expo Risk Assess pmid:24444393
Gautam M et al. Importance of fatty acid compositions in patients with peripheral arterial disease. 2014 PLoS ONE pmid:25191963
Freund Levi Y et al. Transfer of omega-3 fatty acids across the blood-brain barrier after dietary supplementation with a docosahexaenoic acid-rich omega-3 fatty acid preparation in patients with Alzheimer's disease: the OmegAD study. 2014 J. Intern. Med. pmid:24410954
Russell CD and Schwarze J The role of pro-resolution lipid mediators in infectious disease. 2014 Immunology pmid:24400794
O'Callaghan N et al. Telomere shortening in elderly individuals with mild cognitive impairment may be attenuated with ω-3 fatty acid supplementation: a randomized controlled pilot study. 2014 Nutrition pmid:24342530
AlSaleh A et al. Interaction between a CSK gene variant and fish oil intake influences blood pressure in healthy adults. 2014 J. Nutr. pmid:24401815
Patterson AC et al. The percentage of DHA in erythrocytes can detect non-adherence to advice to increase EPA and DHA intakes. 2014 Br. J. Nutr. pmid:23920312
Yang P et al. Anticancer activity of fish oils against human lung cancer is associated with changes in formation of PGE2 and PGE3 and alteration of Akt phosphorylation. 2014 Mol. Carcinog. pmid:23371504
Dendelé B et al. Protective action of n-3 fatty acids on benzo[a]pyrene-induced apoptosis through the plasma membrane remodeling-dependent NHE1 pathway. 2014 Chem. Biol. Interact. pmid:24246761
Murali G et al. Differential effects of eicosapentaenoic acid and docosahexaenoic acid in promoting the differentiation of 3T3-L1 preadipocytes. 2014 Prostaglandins Leukot. Essent. Fatty Acids pmid:24332315
Walhovd KB et al. Blood markers of fatty acids and vitamin D, cardiovascular measures, body mass index, and physical activity relate to longitudinal cortical thinning in normal aging. 2014 Neurobiol. Aging pmid:24332985
Macdonald RL Fish oil for subarachnoid hemorrhage--this is not snake oil. 2014 World Neurosurg pmid:23159655
Hashimoto M et al. Possibility of polyunsaturated fatty acids for the prevention and treatment of neuropsychiatric illnesses. 2014 J. Pharmacol. Sci. pmid:24561447
von Schacky C Omega-3 index and cardiovascular health. 2014 Nutrients pmid:24566438
Yang Y et al. Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species. 2014 Lipids pmid:24777581
Giovannelli J et al. Validation of a short, qualitative food frequency questionnaire in French adults participating in the MONA LISA-NUT study 2005-2007. 2014 J Acad Nutr Diet pmid:24083967
Ganesan B et al. Fortification of foods with omega-3 polyunsaturated fatty acids. 2014 Crit Rev Food Sci Nutr pmid:24188235
Pilkington SM et al. Impact of EPA ingestion on COX- and LOX-mediated eicosanoid synthesis in skin with and without a pro-inflammatory UVR challenge--report of a randomised controlled study in humans. 2014 Mol Nutr Food Res pmid:24311515
Yoneda H et al. A prospective, multicenter, randomized study of the efficacy of eicosapentaenoic acid for cerebral vasospasm: the EVAS study. 2014 World Neurosurg pmid:23032083
Ponnampalam EN et al. Sources of variation of health claimable long chain omega-3 fatty acids in meat from Australian lamb slaughtered at similar weights. 2014 Meat Sci. pmid:23265412
Park J et al. Reciprocal modulation of surface expression of annexin A2 in a human umbilical vein endothelial cell-derived cell line by eicosapentaenoic acid and docosahexaenoic acid. 2014 PLoS ONE pmid:24465474
Zheng MG et al. Cloning, expression and stress-respondent transcription of long-chain acyl-coenzyme A synthetase cDNA gene of Nannochloropsis gaditana and its involvement in the biosynthesis of eicosapentaenoic and decosahexaenoic acids. 2014 Biotechnol. Lett. pmid:24068506
Gregory MK et al. Effect of dietary canola oil on long-chain omega-3 fatty acid content in broiler hearts. 2014 J Anim Physiol Anim Nutr (Berl) pmid:23510129
de Waal H et al. The effect of souvenaid on functional brain network organisation in patients with mild Alzheimer's disease: a randomised controlled study. 2014 PLoS ONE pmid:24475144
James MJ et al. Pitfalls in the use of randomised controlled trials for fish oil studies with cardiac patients. 2014 Br. J. Nutr. pmid:24933212
Harris WS et al. Comparative effects of an acute dose of fish oil on omega-3 fatty acid levels in red blood cells versus plasma: implications for clinical utility. 2013 Sep-Oct J Clin Lipidol pmid:24079284
Tatsuno I et al. Long-term safety and efficacy of TAK-085 in Japanese subjects with hypertriglyceridemia undergoing lifestyle modification: the omega-3 fatty acids randomized long-term (ORL) study. 2013 Nov-Dec J Clin Lipidol pmid:24314359
Igarashi M et al. Kinetics of eicosapentaenoic acid in brain, heart and liver of conscious rats fed a high n-3 PUFA containing diet. 2013 Nov-Dec Prostaglandins Leukot. Essent. Fatty Acids pmid:24209500
Fenton JI et al. Immunomodulation by dietary long chain omega-3 fatty acids and the potential for adverse health outcomes. 2013 Nov-Dec Prostaglandins Leukot. Essent. Fatty Acids pmid:24183073
Tatsuno I et al. Efficacy and safety of TAK-085 compared with eicosapentaenoic acid in Japanese subjects with hypertriglyceridemia undergoing lifestyle modification: the omega-3 fatty acids randomized double-blind (ORD) study. 2013 May-Jun J Clin Lipidol pmid:23725919
Nishimura RY et al. Breast milk fatty acid composition of women living far from the coastal area in Brazil. 2013 May-Jun J Pediatr (Rio J) pmid:23669215
Zajdel A et al. Polyunsaturated fatty acids inhibit melanoma cell growth in vitro. 2013 Mar-Apr Acta Pol Pharm pmid:23614295
Kanat O et al. Comparison of three different treatment modalities in the management of cancer cachexia. 2013 Mar-Apr Tumori pmid:23748819
Piñeiro-Corrales G et al. [Role of omega-3 fatty acids in cardiovascular disease prevention]. 2013 Jan-Feb Nutr Hosp pmid:23808424
Lotrich FE et al. Anger induced by interferon-alpha is moderated by ratio of arachidonic acid to omega-3 fatty acids. 2013 J Psychosom Res pmid:24182638
Miller BJ et al. Dietary supplements for preventing postnatal depression. 2013 Cochrane Database Syst Rev pmid:24158923
Gerstenblith AT et al. Electroretinographic effects of omega-3 Fatty Acid supplementation on dry age-related macular degeneration. 2013 JAMA Ophthalmol pmid:23494041
Gillingham LG et al. Dietary oils and FADS1-FADS2 genetic variants modulate [13C]α-linolenic acid metabolism and plasma fatty acid composition. 2013 Am. J. Clin. Nutr. pmid:23221573
Hjorth E et al. Omega-3 fatty acids enhance phagocytosis of Alzheimer's disease-related amyloid-β42 by human microglia and decrease inflammatory markers. 2013 J. Alzheimers Dis. pmid:23481688
Raatz SK et al. Dose-dependent consumption of farmed Atlantic salmon (Salmo salar) increases plasma phospholipid n-3 fatty acids differentially. 2013 J Acad Nutr Diet pmid:23351633
Fahrmann JF and Hardman WE Omega 3 fatty acids increase the chemo-sensitivity of B-CLL-derived cell lines EHEB and MEC-2 and of B-PLL-derived cell line JVM-2 to anti-cancer drugs doxorubicin, vincristine and fludarabine. 2013 Lipids Health Dis pmid:23497075
Usami M et al. Analysis of fecal microbiota, organic acids and plasma lipids in hepatic cancer patients with or without liver cirrhosis. 2013 Clin Nutr pmid:23068014
Carvalho SC et al. EPA protects against muscle damage in the mdx mouse model of Duchenne muscular dystrophy by promoting a shift from the M1 to M2 macrophage phenotype. 2013 J. Neuroimmunol. pmid:24090650
Moallem U et al. Dietary α-linolenic acid from flaxseed oil improved folliculogenesis and IVF performance in dairy cows, similar to eicosapentaenoic and docosahexaenoic acids from fish oil. 2013 Reproduction pmid:24062566
Ueda M et al. Therapeutic impact of eicosapentaenoic acid on ischemic brain damage following transient focal cerebral ischemia in rats. 2013 Brain Res. pmid:23643859
Sakuradani E et al. Metabolic engineering for the production of polyunsaturated fatty acids by oleaginous fungus Mortierella alpina 1S-4. 2013 J. Biosci. Bioeng. pmid:23648102
Salvati S et al. Ethyl-eicosapentaenoic acid ameliorates the clinical course of experimental allergic encephalomyelitis induced in dark agouti rats. 2013 J. Nutr. Biochem. pmid:23642735
Codabaccus MB et al. Restoration of EPA and DHA in rainbow trout (Oncorhynchus mykiss) using a finishing fish oil diet at two different water temperatures. 2013 Food Chem pmid:23768353
Kangari H et al. Short-term consumption of oral omega-3 and dry eye syndrome. 2013 Ophthalmology pmid:23642375
Costa S et al. The emerging farmed fish species meagre (Argyrosomus regius): how culinary treatment affects nutrients and contaminants concentration and associated benefit-risk balance. 2013 Food Chem. Toxicol. pmid:23900006
Chung ML et al. Profiling of oxidized lipid products of marine fish under acute oxidative stress. 2013 Food Chem. Toxicol. pmid:23220612
Kuma H et al. Beneficial effect of EPA (20:5 n-3 PUFA) on preventing venous thromboembolism: a rat tail thrombosis model experiment. 2013 Thromb. Res. pmid:23040087
Kawashima M et al. Calorie restriction (CR) and CR mimetics for the prevention and treatment of age-related eye disorders. 2013 Exp. Gerontol. pmid:23588119
Neuhofer A et al. Impaired local production of proresolving lipid mediators in obesity and 17-HDHA as a potential treatment for obesity-associated inflammation. 2013 Diabetes pmid:23349501
Fujihara M et al. Reduced plasma eicosapentaenoic acid-arachidonic acid ratio in peripheral artery disease. 2013 Angiology pmid:22371626