EPA

Epa is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 19347 references associated with EPA in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for EPA

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with EPA

MeSH term MeSH ID Detail
Pancreatic Neoplasms D010190 77 associated lipids
Inflammation D007249 119 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 1 D003922 56 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Fatty Liver D005234 48 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Per page 10 20 50 100 | Total 140

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with EPA

Download all related citations
Per page 10 20 50 100 | Total 4880
Authors Title Published Journal PubMed Link
Ðurendić-Brenesel M et al. Hypolipidemic and antioxidant effects of buckwheat leaf and flower mixture in hyperlipidemic rats. 2013 Bosn J Basic Med Sci pmid:23725506
Chen F et al. Fish oil attenuates liver injury caused by LPS in weaned pigs associated with inhibition of TLR4 and nucleotide-binding oligomerization domain protein signaling pathways. 2013 Innate Immun pmid:23339927
Lotrich FE et al. Anger induced by interferon-alpha is moderated by ratio of arachidonic acid to omega-3 fatty acids. 2013 J Psychosom Res pmid:24182638
Wang TM et al. Docosahexaenoic acid and eicosapentaenoic acid reduce C-reactive protein expression and STAT3 activation in IL-6-treated HepG2 cells. 2013 Mol. Cell. Biochem. pmid:23361365
Simon MC et al. Fatty acids modulate cytokine and chemokine secretion of stimulated human whole blood cultures in diabetes. 2013 Clin. Exp. Immunol. pmid:23600826
Xu J et al. Expression of a type 2 diacylglycerol acyltransferase from Thalassiosira pseudonana in yeast leads to incorporation of docosahexaenoic acid β-oxidation intermediates into triacylglycerol. 2013 FEBS J. pmid:24128189
Casey JM et al. Effect of stearidonic acid-enriched soybean oil on fatty acid profile and metabolic parameters in lean and obese Zucker rats. 2013 Lipids Health Dis pmid:24139088
Miller BJ et al. Dietary supplements for preventing postnatal depression. 2013 Cochrane Database Syst Rev pmid:24158923
Al-Taan O et al. Changes in plasma and erythrocyte omega-6 and omega-3 fatty acids in response to intravenous supply of omega-3 fatty acids in patients with hepatic colorectal metastases. 2013 Lipids Health Dis pmid:23648075
Marze S et al. In vitro digestion of fish oils rich in n-3 polyunsaturated fatty acids studied in emulsion and at the oil-water interface. 2013 Food Funct pmid:23086175
Paschoal VA et al. Eicosapentaenoic (EPA) and docosahexaenoic (DHA) acid differentially modulate rat neutrophil function in vitro. 2013 Lipids pmid:23086551
Gerstenblith AT et al. Electroretinographic effects of omega-3 Fatty Acid supplementation on dry age-related macular degeneration. 2013 JAMA Ophthalmol pmid:23494041
Cartiff SE et al. Eicosapentaenoic and docosahexaenoic acids increase insulin sensitivity in growing steers. 2013 J. Anim. Sci. pmid:23463554
Kataoka Y et al. Epanova(®) and hypertriglyceridemia: pharmacological mechanisms and clinical efficacy. 2013 Future Cardiol pmid:23463969
Mocking RJ et al. Relationship between the hypothalamic-pituitary-adrenal-axis and fatty acid metabolism in recurrent depression. 2013 Psychoneuroendocrinology pmid:23465556
Hara M et al. Low levels of serum n-3 polyunsaturated fatty acids are associated with worse heart failure-free survival in patients after acute myocardial infarction. 2013 Circ. J. pmid:23047296
Dobson EP et al. Controlled formation of mono- and dihydroxy-resolvins from EPA and DHA using soybean 15-lipoxygenase. 2013 J. Lipid Res. pmid:23471029
Gillingham LG et al. Dietary oils and FADS1-FADS2 genetic variants modulate [13C]α-linolenic acid metabolism and plasma fatty acid composition. 2013 Am. J. Clin. Nutr. pmid:23221573
Hjorth E et al. Omega-3 fatty acids enhance phagocytosis of Alzheimer's disease-related amyloid-β42 by human microglia and decrease inflammatory markers. 2013 J. Alzheimers Dis. pmid:23481688
Raatz SK et al. Dose-dependent consumption of farmed Atlantic salmon (Salmo salar) increases plasma phospholipid n-3 fatty acids differentially. 2013 J Acad Nutr Diet pmid:23351633
MacIntosh BA et al. Low-n-6 and low-n-6 plus high-n-3 diets for use in clinical research. 2013 Br. J. Nutr. pmid:23328113
Saw CL et al. Astaxanthin and omega-3 fatty acids individually and in combination protect against oxidative stress via the Nrf2-ARE pathway. 2013 Food Chem. Toxicol. pmid:24157545
Klein GL et al. Gut barrier dysfunction and microbial translocation in cancer cachexia: a new therapeutic target. 2013 Curr Opin Support Palliat Care pmid:24157715
Fahrmann JF and Hardman WE Omega 3 fatty acids increase the chemo-sensitivity of B-CLL-derived cell lines EHEB and MEC-2 and of B-PLL-derived cell line JVM-2 to anti-cancer drugs doxorubicin, vincristine and fludarabine. 2013 Lipids Health Dis pmid:23497075
Usami M et al. Analysis of fecal microbiota, organic acids and plasma lipids in hepatic cancer patients with or without liver cirrhosis. 2013 Clin Nutr pmid:23068014
Ruiz-Lopez N et al. Reconstitution of EPA and DHA biosynthesis in arabidopsis: iterative metabolic engineering for the synthesis of n-3 LC-PUFAs in transgenic plants. 2013 Metab. Eng. pmid:23500000
Zhu M et al. Resolvin E1 regulates osteoclast fusion via DC-STAMP and NFATc1. 2013 FASEB J. pmid:23629863
Gladyshev MI et al. Production of EPA and DHA in aquatic ecosystems and their transfer to the land. 2013 Prostaglandins Other Lipid Mediat. pmid:23500063
Carvalho SC et al. EPA protects against muscle damage in the mdx mouse model of Duchenne muscular dystrophy by promoting a shift from the M1 to M2 macrophage phenotype. 2013 J. Neuroimmunol. pmid:24090650
Mozaffari-Khosravi H et al. Eicosapentaenoic acid versus docosahexaenoic acid in mild-to-moderate depression: a randomized, double-blind, placebo-controlled trial. 2013 Eur Neuropsychopharmacol pmid:22910528
Aktas BH et al. Small-Molecule targeting of translation initiation for cancer therapy. 2013 Oncotarget pmid:24091475
Moallem U et al. Dietary α-linolenic acid from flaxseed oil improved folliculogenesis and IVF performance in dairy cows, similar to eicosapentaenoic and docosahexaenoic acids from fish oil. 2013 Reproduction pmid:24062566
Yip PK et al. The omega-3 fatty acid eicosapentaenoic acid accelerates disease progression in a model of amyotrophic lateral sclerosis. 2013 PLoS ONE pmid:23620776
Ueda M et al. Therapeutic impact of eicosapentaenoic acid on ischemic brain damage following transient focal cerebral ischemia in rats. 2013 Brain Res. pmid:23643859
Arem H et al. Omega-3 and omega-6 fatty acid intakes and endometrial cancer risk in a population-based case-control study. 2013 Eur J Nutr pmid:22915050
Sakuradani E et al. Metabolic engineering for the production of polyunsaturated fatty acids by oleaginous fungus Mortierella alpina 1S-4. 2013 J. Biosci. Bioeng. pmid:23648102
Rahman MM et al. DHA is a more potent inhibitor of breast cancer metastasis to bone and related osteolysis than EPA. 2013 Breast Cancer Res. Treat. pmid:24062211
Salvati S et al. Ethyl-eicosapentaenoic acid ameliorates the clinical course of experimental allergic encephalomyelitis induced in dark agouti rats. 2013 J. Nutr. Biochem. pmid:23642735
Miller E et al. A short-term n-3 DPA supplementation study in humans. 2013 Eur J Nutr pmid:22729967
Safarinejad MR et al. Effects of EPA, γ-linolenic acid or coenzyme Q10 on serum prostate-specific antigen levels: a randomised, double-blind trial. 2013 Br. J. Nutr. pmid:23199523
Vigerust NF et al. Krill oil versus fish oil in modulation of inflammation and lipid metabolism in mice transgenic for TNF-α. 2013 Eur J Nutr pmid:22923017
Orozco-Solano MI et al. Analysis of esterified and nonesterified fatty acids in serum from obese individuals after intake of breakfasts prepared with oils heated at frying temperature. 2013 Anal Bioanal Chem pmid:23657457
Pirman DA et al. Changes in cancer cell metabolism revealed by direct sample analysis with MALDI mass spectrometry. 2013 PLoS ONE pmid:23658609
Turkez H and Aydin E Anti-genotoxic role of eicosapentaenoic acid against imazalil-induced DNA damage in vitro. 2013 Toxicol Ind Health pmid:22317822
Watanabe S and Tsuneyama K Eicosapentaenoic acid attenuates hepatic accumulation of cholesterol esters but aggravates liver injury and inflammation in mice fed a cholate-supplemented high-fat diet. 2013 J Toxicol Sci pmid:23665937
Isobe Y et al. Stereochemical assignment and anti-inflammatory properties of the omega-3 lipid mediator resolvin E3. 2013 J. Biochem. pmid:23293324
Tu WC et al. Correlations between blood and tissue omega-3 LCPUFA status following dietary ALA intervention in rats. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:22521090
Tapsell LC et al. Foods, nutrients or whole diets: effects of targeting fish and LCn3PUFA consumption in a 12mo weight loss trial. 2013 BMC Public Health pmid:24369765
Muldoon MF et al. Concurrent physical activity modifies the association between n3 long-chain fatty acids and cardiometabolic risk in midlife adults. 2013 J. Nutr. pmid:23884386
Mocellin MC et al. Fish oil decreases C-reactive protein/albumin ratio improving nutritional prognosis and plasma fatty acid profile in colorectal cancer patients. 2013 Lipids pmid:23888317
Zhang J et al. Different intakes of n-3 fatty acids among pregnant women in 3 regions of China with contrasting dietary patterns are reflected in maternal but not in umbilical erythrocyte phosphatidylcholine fatty acid composition. 2013 Nutr Res pmid:23890350
Shiraishi M et al. Estimation of eicosapentaenoic acid and docosahexaenoic acid intakes in pregnant Japanese women without nausea by using a self-administered diet history questionnaire. 2013 Nutr Res pmid:23746563
Samieri C et al. Relationship between diet and plasma long-chain n-3 PUFAs in older people: impact of apolipoprotein E genotype. 2013 J. Lipid Res. pmid:23801662
Wu JH et al. Plasma phospholipid omega-3 fatty acids and incidence of postoperative atrial fibrillation in the OPERA trial. 2013 J Am Heart Assoc pmid:24145742
Fietkau R et al. A disease-specific enteral nutrition formula improves nutritional status and functional performance in patients with head and neck and esophageal cancer undergoing chemoradiotherapy: results of a randomized, controlled, multicenter trial. 2013 Cancer pmid:23765693
Weiss GA et al. High levels of anti-inflammatory and pro-resolving lipid mediators lipoxins and resolvins and declining docosahexaenoic acid levels in human milk during the first month of lactation. 2013 Lipids Health Dis pmid:23767972
Codabaccus MB et al. Restoration of EPA and DHA in rainbow trout (Oncorhynchus mykiss) using a finishing fish oil diet at two different water temperatures. 2013 Food Chem pmid:23768353
Alhazzaa R et al. Bioconversion of α-linolenic acid into n-3 long-chain polyunsaturated fatty acid in hepatocytes and ad hoc cell culture optimisation. 2013 PLoS ONE pmid:24040040
Juman S et al. Effects of long-term oral administration of arachidonic acid and docosahexaenoic acid on the immune functions of young rats. 2013 Nutrients pmid:23760060
Oshima Y et al. Serum eicosapentaenoic acid/arachidonic acid ratio is low in patients with pulmonary thromboembolism. 2013 J. Nutr. Sci. Vitaminol. pmid:24418883
Laird BD et al. Dietary advice on Inuit traditional food use needs to balance benefits and risks of mercury, selenium, and n3 fatty acids. 2013 J. Nutr. pmid:23616502
Sala-Vila A et al. Eicosapentaenoic acid in serum phospholipids relates to a less atherogenic lipoprotein profile in subjects with familial hypercholesterolemia. 2013 J. Nutr. Biochem. pmid:23618530
Gdula-Argasińska J et al. Identification of lipid derivatives in Hep G2 cells. 2013 Acta Biochim. Pol. pmid:24432338
Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. 2013 JAMA pmid:23644932
Meyer BJ et al. Assessing long-chain ω-3 polyunsaturated fatty acids: a tailored food-frequency questionnaire is better. 2013 Nutrition pmid:22929186
Stephenson JA et al. Unsaturated fatty acids differ between hepatic colorectal metastases and liver tissue without tumour in humans: results from a randomised controlled trial of intravenous eicosapentaenoic and docosahexaenoic acids. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:23647811
Lemke SL et al. Consumption of stearidonic acid-rich oil in foods increases red blood cell eicosapentaenoic acid. 2013 J Acad Nutr Diet pmid:23885702
Johnston DT et al. Red blood cell omega-3 fatty acid levels and neurocognitive performance in deployed U.S. Servicemembers. 2013 Nutr Neurosci pmid:22748167
Kawabata T et al. Influences of stearidonic acid-enriched soybean oil on the blood and organ biochemical parameters in rats. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:23219237
Hamaoka N et al. Oxidative stability of lipids rich in EPA and DHA extracted from fermented scallop ovary. 2013 J. Food Sci. pmid:23915081
Flock MR et al. Immunometabolic role of long-chain omega-3 fatty acids in obesity-induced inflammation. 2013 Diabetes Metab. Res. Rev. pmid:23592441
Bertrand C et al. Effects of dietary eicosapentaenoic acid (EPA) supplementation in high-fat fed mice on lipid metabolism and apelin/APJ system in skeletal muscle. 2013 PLoS ONE pmid:24244380
Kangari H et al. Short-term consumption of oral omega-3 and dry eye syndrome. 2013 Ophthalmology pmid:23642375
Nelson SD and Munger MA Icosapent ethyl for treatment of elevated triglyceride levels. 2013 Ann Pharmacother pmid:24259598
Ramprasath VR et al. Enhanced increase of omega-3 index in healthy individuals with response to 4-week n-3 fatty acid supplementation from krill oil versus fish oil. 2013 Lipids Health Dis pmid:24304605
Fu Y et al. The desaturase OPIN17 from Phytophthora infestans converts arachidonic acid to eicosapentaenoic acid in CHO cells. 2013 Appl. Biochem. Biotechnol. pmid:23912207
Costa S et al. The emerging farmed fish species meagre (Argyrosomus regius): how culinary treatment affects nutrients and contaminants concentration and associated benefit-risk balance. 2013 Food Chem. Toxicol. pmid:23900006
Mühlroth A et al. Pathways of lipid metabolism in marine algae, co-expression network, bottlenecks and candidate genes for enhanced production of EPA and DHA in species of Chromista. 2013 Mar Drugs pmid:24284429
Fogagnolo Mauricio A et al. Effects of fish oil containing eicosapentaenoic acid and docosahexaenoic acid on dystrophic mdx mice. 2013 Clin Nutr pmid:23218947
Chung ML et al. Profiling of oxidized lipid products of marine fish under acute oxidative stress. 2013 Food Chem. Toxicol. pmid:23220612
van der Merwe LF et al. Long-chain PUFA supplementation in rural African infants: a randomized controlled trial of effects on gut integrity, growth, and cognitive development. 2013 Am. J. Clin. Nutr. pmid:23221579
Das UN Autism as a disorder of deficiency of brain-derived neurotrophic factor and altered metabolism of polyunsaturated fatty acids. 2013 Nutrition pmid:23911220
Yee LD et al. The inhibition of early stages of HER-2/neu-mediated mammary carcinogenesis by dietary n-3 PUFAs. 2013 Mol Nutr Food Res pmid:23213007
Nikolakopoulou Z et al. Omega-3 polyunsaturated fatty acids selectively inhibit growth in neoplastic oral keratinocytes by differentially activating ERK1/2. 2013 Carcinogenesis pmid:23892603
Kuma H et al. Beneficial effect of EPA (20:5 n-3 PUFA) on preventing venous thromboembolism: a rat tail thrombosis model experiment. 2013 Thromb. Res. pmid:23040087
Sato K et al. Selective and potent inhibitory effect of docosahexaenoic acid (DHA) on U46619-induced contraction in rat aorta. 2013 J Smooth Muscle Res pmid:24304639
Innis SM et al. Long chain omega-3 fatty acids: micronutrients in disguise. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:22709913
Kawashima M et al. Calorie restriction (CR) and CR mimetics for the prevention and treatment of age-related eye disorders. 2013 Exp. Gerontol. pmid:23588119
Yusof HM et al. Limited impact of 2 g/day omega-3 fatty acid ethyl esters (Omacor®) on plasma lipids and inflammatory markers in patients awaiting carotid endarterectomy. 2013 Mar Drugs pmid:24065166
Xiao G et al. Eicosapentaenoic acid enhances heat stress-impaired intestinal epithelial barrier function in Caco-2 cells. 2013 PLoS ONE pmid:24066055
Jaudszus A et al. Evaluation of suppressive and pro-resolving effects of EPA and DHA in human primary monocytes and T-helper cells. 2013 J. Lipid Res. pmid:23349208
Babaahmadi Rezaei H et al. Compare the effect of eicosapentaenoic acid and oxidized low-density lipoprotein on the expression of CD36 and peroxisome proliferator-activated receptor gamma. 2013 Iran. Biomed. J. pmid:23567850
Neuhofer A et al. Impaired local production of proresolving lipid mediators in obesity and 17-HDHA as a potential treatment for obesity-associated inflammation. 2013 Diabetes pmid:23349501
Sofi F et al. The atherosclerotic risk profile is affected differently by fish flesh with a similar EPA and DHA content but different n-6/n-3 ratio. 2013 Asia Pac J Clin Nutr pmid:23353608
Oner G and Muderris II Efficacy of omega-3 in the treatment of polycystic ovary syndrome. 2013 J Obstet Gynaecol pmid:23550861
Gustafsson SB et al. Effects of cannabinoids and related fatty acids upon the viability of P19 embryonal carcinoma cells. 2013 Arch. Toxicol. pmid:23552853
McEwen BJ et al. Effects of omega-3 polyunsaturated fatty acids on platelet function in healthy subjects and subjects with cardiovascular disease. 2013 Semin. Thromb. Hemost. pmid:23329646
Fujihara M et al. Reduced plasma eicosapentaenoic acid-arachidonic acid ratio in peripheral artery disease. 2013 Angiology pmid:22371626
Lyons MR et al. Impact of sex on the heart's metabolic and functional responses to diabetic therapies. 2013 Am. J. Physiol. Heart Circ. Physiol. pmid:24043256
Ballantyne CM et al. Icosapent ethyl for the treatment of hypertriglyceridemia. 2013 Expert Opin Pharmacother pmid:23701295