EPA

Epa is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 19347 references associated with EPA in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for EPA

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with EPA

MeSH term MeSH ID Detail
Tuberculosis D014376 20 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Sarcoma, Experimental D012513 13 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Hyperglycemia D006943 21 associated lipids
Per page 10 20 50 100 | Total 140

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with EPA

Download all related citations
Per page 10 20 50 100 | Total 4880
Authors Title Published Journal PubMed Link
pmid:
Furukawa K et al. Effects of soybean oil emulsion and eicosapentaenoic acid on stress response and immune function after a severely stressful operation. 1999 Ann. Surg. pmid:10024108
Mayol V et al. Cholesterol and omega-3 fatty acids inhibit Na, K-ATPase activity in human endothelial cells. 1999 Atherosclerosis pmid:10030384
Adan Y et al. Effects of docosahexaenoic and eicosapentaenoic acid on lipid metabolism, eicosanoid production, platelet aggregation and atherosclerosis in hypercholesterolemic rats. 1999 Biosci. Biotechnol. Biochem. pmid:10052130
Hung P et al. Dietary effect of EPA-rich and DHA-rich fish oils on the immune function of Sprague-Dawley rats. 1999 Biosci. Biotechnol. Biochem. pmid:10052133
Ghioni C et al. Low C18 to C20 fatty acid elongase activity and limited conversion of stearidonic acid, 18:4(n-3), to eicosapentaenoic acid, 20:5(n-3), in a cell line from the turbot, Scophthalmus maximus. 1999 Biochim. Biophys. Acta pmid:10064900
Andriamampandry MD et al. Antithrombotic effects of (n-3) polyunsaturated fatty acids in rat models of arterial and venous thrombosis. 1999 Thromb. Res. pmid:10065894
Lo CJ et al. Fish oil decreases macrophage tumor necrosis factor gene transcription by altering the NF kappa B activity. 1999 J. Surg. Res. pmid:10090832
Barber MD et al. The anti-cachectic effect of fatty acids. 1998 Proc Nutr Soc pmid:10096118
Shamsudin L Seasonal variation of fatty acid content in natural microplankton from the Tumpat coastal waters of the South China Sea. 1998 Arch. Physiol. Biochem. pmid:10099722
Xu HE et al. Molecular recognition of fatty acids by peroxisome proliferator-activated receptors. 1999 Mol. Cell pmid:10198642
Leng GC et al. Randomized controlled trial of gamma-linolenic acid and eicosapentaenoic acid in peripheral arterial disease. 1998 Clin Nutr pmid:10205349
Tagawa H et al. Long-term treatment with eicosapentaenoic acid augments both nitric oxide-mediated and non-nitric oxide-mediated endothelium-dependent forearm vasodilatation in patients with coronary artery disease. 1999 J. Cardiovasc. Pharmacol. pmid:10218735
Connor WE Alpha-linolenic acid in health and disease. 1999 Am. J. Clin. Nutr. pmid:10232618
Billman GE et al. Prevention of sudden cardiac death by dietary pure omega-3 polyunsaturated fatty acids in dogs. 1999 Circulation pmid:10318669
Haggarty P et al. Effect of maternal polyunsaturated fatty acid concentration on transport by the human placenta. 1999 Biol. Neonate pmid:10325438
Pakala R et al. Serotonin-induced endothelial cell proliferation is blocked by omega-3 fatty acids. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10328332
Rodrigo GC et al. Effects of eicosapentaenoic acid on the contraction of intact, and spontaneous contraction of chemically permeabilized mammalian ventricular myocytes. 1999 J. Mol. Cell. Cardiol. pmid:10329201
Hun CS et al. Increased uncoupling protein2 mRNA in white adipose tissue, and decrease in leptin, visceral fat, blood glucose, and cholesterol in KK-Ay mice fed with eicosapentaenoic and docosahexaenoic acids in addition to linolenic acid. 1999 Biochem. Biophys. Res. Commun. pmid:10334920
Roberts LJ et al. Novel eicosanoids. Isoprostanes and related compounds. 1999 Methods Mol. Biol. pmid:10343322
Shahar E et al. Docosahexaenoic acid and smoking-related chronic obstructive pulmonary disease. The Atherosclerosis Risk in Communities Study Investigators. 1999 Am. J. Respir. Crit. Care Med. pmid:10351918
Meuillet EJ et al. Incorporation of exogenous lipids modulates insulin signaling in the hepatoma cell line, HepG2. 1999 Biochim. Biophys. Acta pmid:10354513
Nakamura N et al. Joint effects of HMG-CoA reductase inhibitors and eicosapentaenoic acids on serum lipid profile and plasma fatty acid concentrations in patients with hyperlipidemia. 1999 Int. J. Clin. Lab. Res. pmid:10356659
Kotkat HM et al. Effect of dietary fish oil (active EPA-30) on liver phospholipids in young and aged rats. 1999 Comp. Biochem. Physiol., Part A Mol. Integr. Physiol. pmid:10356759
Barichello JM et al. Enhanced rectal absorption of insulin-loaded Pluronic F-127 gels containing unsaturated fatty acids. 1999 Int J Pharm pmid:10361163
Morita I [Regulation of angiogenesis-expression of VEGF receptors]. 1998 Hum. Cell pmid:10363159
Bayorh MA et al. Enhanced nitric oxide synthesis reverses salt-induced alterations in blood flow and cGMP levels. 1999 Clin. Exp. Hypertens. pmid:10369379
Hussey HJ and Tisdale MJ Effect of a cachectic factor on carbohydrate metabolism and attenuation by eicosapentaenoic acid. 1999 Br. J. Cancer pmid:10376976
Madsen L and Berge RK 3-Thia fatty acid treatment, in contrast to eicosapentaenoic acid and starvation, induces gene expression of carnitine palmitoyltransferase-II in rat liver. 1999 Lipids pmid:10380116
Katsumata T et al. Delayed administration of ethyl eicosapentate improves local cerebral blood flow and metabolism without affecting infarct volumes in the rat focal ischemic model. 1999 Eur. J. Pharmacol. pmid:10395096
Pakala R et al. Thromboxane A2 fails to induce proliferation of smooth muscle cells enriched with eicosapentaenoic acid and docosahexaenoic acid. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10397410
Andersen LF et al. Evaluation of a food frequency questionnaire with weighed records, fatty acids, and alpha-tocopherol in adipose tissue and serum. 1999 Am. J. Epidemiol. pmid:10400557
Murakami K et al. Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha. 1999 Biochem. Biophys. Res. Commun. pmid:10403814
Løssl K et al. The effect of n-3 fatty acids on leukotriene formation from neutrophils in patients on hemodialysis. 1999 Lipids pmid:10419143
McCabe AJ et al. The effect of eicosapentanoic acid on matrix metalloproteinase gene expression. 1999 Lipids pmid:10419155
Li D et al. Comparison of n-3 polyunsaturated fatty acids from vegetable oils, meat, and fish in raising platelet eicosapentaenoic acid levels in humans. 1999 Lipids pmid:10419187
Pakala R et al. Serotonin fails to induce proliferation of endothelial cells preloaded with eicosapentaenoic acid and docosahexaenoic acid. 1999 Atherosclerosis pmid:10428304
von Meyenfeldt MF Nutritional support during treatment of biliopancreatic malignancy. 1999 Ann. Oncol. pmid:10436839
Matsukawa R et al. Eicosapentaenoic acid release from the red alga Pachymeniopsis lanceolata by enzymatic degradation. 1999 Appl. Biochem. Biotechnol. pmid:10436916
de Deckere EA Possible beneficial effect of fish and fish n-3 polyunsaturated fatty acids in breast and colorectal cancer. 1999 Eur. J. Cancer Prev. pmid:10443950
Tso P et al. Lymphatic absorption of structured triglycerides vs. physical mix in a rat model of fat malabsorption. 1999 Am. J. Physiol. pmid:10444447
Khozin-Goldberg I et al. Salicylhydroxamic acid inhibits delta6 desaturation in the microalga Porphyridium cruentum. 1999 Biochim. Biophys. Acta pmid:10446425
Matsuyama N et al. Polyunsaturated fatty acid anilides as inhibitors of acyl-coA: cholesterol acyltransferase (ACAT). 1999 Bioorg. Med. Chem. Lett. pmid:10450977
Lo CJ et al. Fish oil augments macrophage cyclooxygenase II (COX-2) gene expression induced by endotoxin. 1999 J. Surg. Res. pmid:10452875
Mori TA et al. Docosahexaenoic acid but not eicosapentaenoic acid lowers ambulatory blood pressure and heart rate in humans. 1999 Hypertension pmid:10454450
Obata T et al. Eicosapentaenoic acid inhibits prostaglandin D2 generation by inhibiting cyclo-oxygenase-2 in cultured human mast cells. 1999 Clin. Exp. Allergy pmid:10457118
Gadek JE et al. Effect of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in patients with acute respiratory distress syndrome. Enteral Nutrition in ARDS Study Group. 1999 Crit. Care Med. pmid:10470743
Chen H et al. Synthesis and release of docosahexaenoic acid by the RPE cells of prcd-affected dogs. 1999 Invest. Ophthalmol. Vis. Sci. pmid:10476811
Zhang YW et al. Pretreatment with eicosapentaenoic acid prevented hypoxia/reoxygenation-induced abnormality in endothelial gap junctional intercellular communication through inhibiting the tyrosine kinase activity. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10477040
Saku N et al. Eicosapentaenoic acid modulates arachidonic acid metabolism in rat alveolar macrophages activated by silica. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10477043
Hishinuma T et al. Effects of long-term supplementation of eicosapentanoic and docosahexanoic acid on the 2-, 3-series prostacyclin production by endothelial cells. 1999 Prostaglandins Other Lipid Mediat. pmid:10480487
Yamamoto D et al. Synergistic action of apoptosis induced by eicosapentaenoic acid and TNP-470 on human breast cancer cells. 1999 Breast Cancer Res. Treat. pmid:10481942
Mori Y et al. Effect of highly purified eicosapentaenoic acid ethyl ester on insulin resistance and hypertension in Dahl salt-sensitive rats. 1999 Metab. Clin. Exp. pmid:10484046
Vaagenes H et al. Methylated eicosapentaenoic acid and tetradecylthioacetic acid: effects on fatty acid metabolism. 1999 Biochem. Pharmacol. pmid:10484071
Barber MD et al. The effect of an oral nutritional supplement enriched with fish oil on weight-loss in patients with pancreatic cancer. 1999 Br. J. Cancer pmid:10487616
Berge RK et al. In contrast with docosahexaenoic acid, eicosapentaenoic acid and hypolipidaemic derivatives decrease hepatic synthesis and secretion of triacylglycerol by decreased diacylglycerol acyltransferase activity and stimulation of fatty acid oxidation. 1999 Biochem. J. pmid:10493929
Asano M et al. Eicosapentaenoic acid inhibits vasopressin-activated Ca2+ influx and cell proliferation in rat aortic smooth muscle cell lines. 1999 Eur. J. Pharmacol. pmid:10497907
Gee JM et al. Consumption of fish oil leads to prompt incorporation of eicosapentaenoic acid into colonic mucosa of patients prior to surgery for colorectal cancer, but has no detectable effect on epithelial cytokinetics. 1999 J. Nutr. pmid:10498759
Ando M et al. Eicosapentanoic acid reduces plasma levels of remnant lipoproteins and prevents in vivo peroxidation of LDL in dialysis patients. 1999 J. Am. Soc. Nephrol. pmid:10505695
Palombo JD et al. Effect of short-term enteral feeding with eicosapentaenoic and gamma-linolenic acids on alveolar macrophage eicosanoid synthesis and bactericidal function in rats. 1999 Crit. Care Med. pmid:10507617
Pakala R et al. Eicosapentaenoic acid and docosahexaenoic acid block serotonin-induced smooth muscle cell proliferation. 1999 Arterioscler. Thromb. Vasc. Biol. pmid:10521359
Véricel E et al. The influence of low intake of n-3 fatty acids on platelets in elderly people. 1999 Atherosclerosis pmid:10525140
Nakayama M et al. Low dose of eicosapentaenoic acid inhibits the exaggerated growth of vascular smooth muscle cells from spontaneously hypertensive rats through suppression of transforming growth factor-beta. 1999 J. Hypertens. pmid:10526902
Chiu LC and Wan JM Induction of apoptosis in HL-60 cells by eicosapentaenoic acid (EPA) is associated with downregulation of bcl-2 expression. 1999 Cancer Lett. pmid:10530765
Surette ME et al. Activation of leukotriene synthesis in human neutrophils by exogenous arachidonic acid: inhibition by adenosine A(2a) receptor agonists and crucial role of autocrine activation by leukotriene B(4). 1999 Mol. Pharmacol. pmid:10531413
Ku K et al. Beneficial effects of omega-3 fatty acid treatment on the recovery of cardiac function after cold storage of hyperlipidemic rats. 1999 Metab. Clin. Exp. pmid:10535379
Xiao Y and Li X Polyunsaturated fatty acids modify mouse hippocampal neuronal excitability during excitotoxic or convulsant stimulation. 1999 Brain Res. pmid:10536218
Katayama Y and Katsumata T [Icosapentate (EPA)]. 1999 Nippon Rinsho pmid:10543064
Saso L et al. Stabilization of rat serum proteins following oral administration of fish oil. 1999 Arch. Pharm. Res. pmid:10549576
Tanaka Y et al. Suppression of prostaglandin synthesis by arachidonic acid or eicosapentaenoic acid in a macrophage-like cell line, RAW 264.7, treated with LPS. 1999 Biol. Pharm. Bull. pmid:10549854
Singh RB GISSI-Prevenzione trial. 1999 Lancet pmid:10551522
Senanayake SP and Shahidi F Enzyme-assisted acidolysis of borage (Borago officinalis L.) and evening primrose (Oenothera biennis L.) oils: incorporation of omega-3 polyunsaturated fatty acids. 1999 J. Agric. Food Chem. pmid:10552616
Smith HJ et al. Effect of a cancer cachectic factor on protein synthesis/degradation in murine C2C12 myoblasts: modulation by eicosapentaenoic acid. 1999 Cancer Res. pmid:10554027
Munger KA et al. Transfection of rat kidney with human 15-lipoxygenase suppresses inflammation and preserves function in experimental glomerulonephritis. 1999 Proc. Natl. Acad. Sci. U.S.A. pmid:10557328
Elmore JS et al. Effect of the polyunsaturated fatty acid composition of beef muscle on the profile of aroma volatiles. 1999 J. Agric. Food Chem. pmid:10564028
Purepa. 1999 Drugs R D pmid:10566043
Arun Kumar C and Das UN Lipid peroxides, nitric oxide and essential fatty acids in patients with Plasmodium falciparum malaria. 1999 Prostaglandins Leukot. Essent. Fatty Acids pmid:10574650
Han JJ and Yamane T Enhancement of both reaction yield and rate of synthesis of structured triacylglycerol containing eicosapentaenoic acid under vacuum with water activity control. 1999 Lipids pmid:10574664
Calviello G et al. Eicosapentaenoic acid inhibits the growth of liver preneoplastic lesions and alters membrane phospholipid composition and peroxisomal beta-oxidation. 1999 Nutr Cancer pmid:10578489
Wolff RL et al. Arachidonic, eicosapentaenoic, and biosynthetically related fatty acids in the seed lipids from a primitive gymnosperm, Agathis robusta. 1999 Lipids pmid:10580336
Norrish AE et al. Prostate cancer risk and consumption of fish oils: a dietary biomarker-based case-control study. 1999 Br. J. Cancer pmid:10584888
Pirich C et al. Effects of fish oil supplementation on platelet survival and ex vivo platelet function in hypercholesterolemic patients. 1999 Thromb. Res. pmid:10588465
Conquer JA et al. Effect of supplementation with dietary seal oil on selected cardiovascular risk factors and hemostatic variables in healthy male subjects. 1999 Thromb. Res. pmid:10588467
Levy R and Herzberg GR Hydrolysis of long-chain, n-3 fatty acid enriched chylomicrons by cardiac lipoprotein lipase. 1999 Can. J. Physiol. Pharmacol. pmid:10588486
Senkal M et al. Outcome and cost-effectiveness of perioperative enteral immunonutrition in patients undergoing elective upper gastrointestinal tract surgery: a prospective randomized study. 1999 Arch Surg pmid:10593328
Kageyama K et al. Cytotoxicity of docosahexaenoic acid and eicosapentaenoic acid in tumor cells and the dependence on binding to serum proteins and incorporation into intracellular lipids. 2000 Jan-Feb Oncol. Rep. pmid:10601596
Retterstøl K et al. The pathway from arachidonic to docosapentaenoic acid (20:4n-6 to 22:5n-6) and from eicosapentaenoic to docosahexaenoic acid (20:5n-3 to 22:6n-3) studied in testicular cells from immature rats. 2000 Biochim. Biophys. Acta pmid:10601701
Yamada M et al. Changes in prostacyclin, thromboxane A2 and F2-isoprostanes, and influence of eicosapentaenoic acid and antiplatelet agents in patients with hypertension and hyperlipidemia. 1999 Immunopharmacology pmid:10604544
Nitsan Z et al. Enrichment of poultry products with omega3 fatty acids by dietary supplementation with the alga Nannochloropsis and mantur oil. 1999 J. Agric. Food Chem. pmid:10606584
Richardson AJ et al. Laterality changes accompanying symptom remission in schizophrenia following treatment with eicosapentaenoic acid. 1999 Int J Psychophysiol pmid:10610057
Leng GC et al. Essential fatty acids and cardiovascular disease: the Edinburgh Artery Study. 1999 Vasc Med pmid:10613625
Connor WE Importance of n-3 fatty acids in health and disease. 2000 Am. J. Clin. Nutr. pmid:10617967
Kang JX and Leaf A Prevention of fatal cardiac arrhythmias by polyunsaturated fatty acids. 2000 Am. J. Clin. Nutr. pmid:10617972
Makrides M and Gibson RA Long-chain polyunsaturated fatty acid requirements during pregnancy and lactation. 2000 Am. J. Clin. Nutr. pmid:10617987
James MJ et al. Dietary polyunsaturated fatty acids and inflammatory mediator production. 2000 Am. J. Clin. Nutr. pmid:10617994
Kremer JM n-3 fatty acid supplements in rheumatoid arthritis. 2000 Am. J. Clin. Nutr. pmid:10617995
Hughes DA and Pinder AC n-3 polyunsaturated fatty acids inhibit the antigen-presenting function of human monocytes. 2000 Am. J. Clin. Nutr. pmid:10617997
Donadio JV Use of fish oil to treat patients with immunoglobulin a nephropathy. 2000 Am. J. Clin. Nutr. pmid:10618000
Schwartz J Role of polyunsaturated fatty acids in lung disease. 2000 Am. J. Clin. Nutr. pmid:10618003
Engler MB et al. Calcium-mediated mechanisms of eicosapentaenoic acid-induced relaxation in hypertensive rat aorta. 1999 Am. J. Hypertens. pmid:10619586