EPA

Epa is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 19347 references associated with EPA in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for EPA

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with EPA

MeSH term MeSH ID Detail
Tuberculosis D014376 20 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Sarcoma, Experimental D012513 13 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Hyperglycemia D006943 21 associated lipids
Per page 10 20 50 100 | Total 140

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with EPA

Download all related citations
Per page 10 20 50 100 | Total 4880
Authors Title Published Journal PubMed Link
Liu Q et al. Dietary n-6:n-3 ratio and Vitamin E improve motility characteristics in association with membrane properties of boar spermatozoa. 2017 Mar-Apr Asian J. Androl. pmid:26763547
Manni A et al. Stearoyl-CoA desaturase-1, a novel target of omega-3 fatty acids for reducing breast cancer risk in obese postmenopausal women. 2017 Eur J Clin Nutr pmid:28145413
Burak C et al. Effects of the flavonol quercetin and α-linolenic acid on n-3 PUFA status in metabolically healthy men and women: a randomised, double-blinded, placebo-controlled, crossover trial. 2017 Br. J. Nutr. pmid:28366181
Tsuchiya T et al. Involvement of Resveratrol and ω-3 Polyunsaturated Fatty Acids on Sirtuin 1 Gene Expression in THP1 Cells. 2017 Am. J. Med. Sci. pmid:29078847
Yoshikata R et al. Relationship between equol producer status and metabolic parameters in 743 Japanese women: equol producer status is associated with antiatherosclerotic conditions in women around menopause and early postmenopause. 2017 Menopause pmid:27676633
Bhatt DL et al. Rationale and design of REDUCE-IT: Reduction of Cardiovascular Events with Icosapent Ethyl-Intervention Trial. 2017 Clin Cardiol pmid:28294373
Brinton EA and Mason RP Prescription omega-3 fatty acid products containing highly purified eicosapentaenoic acid (EPA). 2017 Lipids Health Dis pmid:28137294
Mosca L et al. Usefulness of Icosapent Ethyl (Eicosapentaenoic Acid Ethyl Ester) in Women to Lower Triglyceride Levels (Results from the MARINE and ANCHOR Trials). 2017 Am. J. Cardiol. pmid:27939227
Neuman JC et al. Enriching Islet Phospholipids With Eicosapentaenoic Acid Reduces Prostaglandin E2 Signaling and Enhances Diabetic β-Cell Function. 2017 Diabetes pmid:28193789
Mirabi P et al. The role of fatty acids on ICSI outcomes: a prospective cohort study. 2017 Lipids Health Dis pmid:28109274
Aslan Ä° et al. Decreased eicosapentaenoic acid levels in acne vulgaris reveals the presence of a proinflammatory state. 2017 Prostaglandins Other Lipid Mediat. pmid:28025036
Lee Y et al. Analysis of endogenous lipids during intestinal wound healing. 2017 PLoS ONE pmid:28800645
Nakamura K et al. Eicosapentaenoic acid prevents arterial calcification in klotho mutant mice. 2017 PLoS ONE pmid:28771600
Yilmaz JL et al. Determination of Substrate Preferences for Desaturases and Elongases for Production of Docosahexaenoic Acid from Oleic Acid in Engineered Canola. 2017 Lipids pmid:28197856
Veselinovic M et al. Clinical Benefits of n-3 PUFA and ɤ-Linolenic Acid in Patients with Rheumatoid Arthritis. 2017 Nutrients pmid:28346333
Savolainen O et al. Biomarkers of food intake and nutrient status are associated with glucose tolerance status and development of type 2 diabetes in older Swedish women. 2017 Am. J. Clin. Nutr. pmid:28903960
Tigistu-Sahle F et al. Metabolism and phospholipid assembly of polyunsaturated fatty acids in human bone marrow mesenchymal stromal cells. 2017 J. Lipid Res. pmid:27856675
Liu Y et al. Eicosapentaenoic Acid-Enriched Phosphatidylcholine Attenuated Hepatic Steatosis Through Regulation of Cholesterol Metabolism in Rats with Nonalcoholic Fatty Liver Disease. 2017 Lipids pmid:28012135
Lefort N et al. Dietary Buglossoides Arvensis Oil Increases Circulating n-3 Polyunsaturated Fatty Acids in a Dose-Dependent Manner and Enhances Lipopolysaccharide-Stimulated Whole Blood Interleukin-10-A Randomized Placebo-Controlled Trial. 2017 Nutrients pmid:28287415
Senftleber NK et al. Marine Oil Supplements for Arthritis Pain: A Systematic Review and Meta-Analysis of Randomized Trials. 2017 Nutrients pmid:28067815
Park H et al. Towards the development of a sustainable soya bean-based feedstock for aquaculture. 2017 Plant Biotechnol. J. pmid:27496594
Alsharari ZD et al. Serum Fatty Acids, Desaturase Activities and Abdominal Obesity - A Population-Based Study of 60-Year Old Men and Women. 2017 PLoS ONE pmid:28125662
Muralikumar S et al. Probing the intermolecular interactions of PPARγ-LBD with polyunsaturated fatty acids and their anti-inflammatory metabolites to infer most potential binding moieties. 2017 Lipids Health Dis pmid:28109294
Boukhris S et al. The Potential of a Brown Microalga Cultivated in High Salt Medium for the Production of High-Value Compounds. 2017 Biomed Res Int pmid:28612024
Ballantyne CM et al. Icosapent ethyl (eicosapentaenoic acid ethyl ester): Effects on plasma apolipoprotein C-III levels in patients from the MARINE and ANCHOR studies. 2016 May-Jun J Clin Lipidol pmid:27206952
Crandell JR et al. Lipid effects of switching from prescription EPA+DHA (omega-3-acid ethyl esters) to prescription EPA only (icosapent ethyl) in dyslipidemic patients. 2016 Postgrad Med pmid:27684412
Kandula M et al. Discovery and preclinical development of a novel prodrug conjugate of mesalamine with eicosapentaenoic acid and caprylic acid for the treatment of inflammatory bowel diseases. 2016 Int. Immunopharmacol. pmid:27716592
Jory J Abnormal fatty acids in Canadian children with autism. 2016 Nutrition pmid:26746679
Park HG et al. Metabolic fate of docosahexaenoic acid (DHA; 22:6n-3) in human cells: direct retroconversion of DHA to eicosapentaenoic acid (20:5n-3) dominates over elongation to tetracosahexaenoic acid (24:6n-3). 2016 FEBS Lett. pmid:27543786
Gose T et al. Prostaglandin transporter (OATP2A1/SLCO2A1) contributes to local disposition of eicosapentaenoic acid-derived PGE3. 2016 Prostaglandins Other Lipid Mediat. pmid:26692285
McManus S et al. Differential effects of EPA versus DHA on postprandial vascular function and the plasma oxylipin profile in men. 2016 J. Lipid Res. pmid:27170732
Nagai T et al. Circulating Omega-6, But Not Omega-3 Polyunsaturated Fatty Acids, Are Associated with Clinical Outcomes in Patients with Acute Decompensated Heart Failure. 2016 PLoS ONE pmid:27824904
Graciano MF et al. Omega-3 fatty acids control productions of superoxide and nitrogen oxide and insulin content in INS-1E cells. 2016 J. Physiol. Biochem. pmid:27474043
Hanssens L et al. The clinical benefits of long-term supplementation with omega-3 fatty acids in cystic fibrosis patients - A pilot study. 2016 Prostaglandins Leukot. Essent. Fatty Acids pmid:27154364
Suzuki-Kemuriyama N et al. Different Effects of Eicosapentaenoic and Docosahexaenoic Acids on Atherogenic High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease in Mice. 2016 PLoS ONE pmid:27333187
Bays HE et al. Icosapent ethyl: Eicosapentaenoic acid concentration and triglyceride-lowering effects across clinical studies. 2016 Prostaglandins Other Lipid Mediat. pmid:27418543
Gold DR et al. Lung VITAL: Rationale, design, and baseline characteristics of an ancillary study evaluating the effects of vitamin D and/or marine omega-3 fatty acid supplements on acute exacerbations of chronic respiratory disease, asthma control, pneumonia and lung function in adults. 2016 Contemp Clin Trials pmid:26784651
Fialkow J Omega-3 Fatty Acid Formulations in Cardiovascular Disease: Dietary Supplements are Not Substitutes for Prescription Products. 2016 Am J Cardiovasc Drugs pmid:27138439
Bassuk SS et al. Baseline characteristics of participants in the VITamin D and OmegA-3 TriaL (VITAL). 2016 Contemp Clin Trials pmid:26767629
Allaire J et al. A randomized, crossover, head-to-head comparison of eicosapentaenoic acid and docosahexaenoic acid supplementation to reduce inflammation markers in men and women: the Comparing EPA to DHA (ComparED) Study. 2016 Am. J. Clin. Nutr. pmid:27281302
Gramer G et al. Long-chain polyunsaturated fatty acid status in children, adolescents and adults with phenylketonuria. 2016 Prostaglandins Leukot. Essent. Fatty Acids pmid:27269713
Dagorn F et al. Exploitable Lipids and Fatty Acids in the Invasive Oyster Crassostrea gigas on the French Atlantic Coast. 2016 Mar Drugs pmid:27231919
Tian Y et al. Bioconversion of Docosapentaenoic Acid in Human Cell Lines, Caco-2, HepG2, and THP-1. 2016 J Oleo Sci pmid:27829615
Markworth JF et al. Divergent shifts in lipid mediator profile following supplementation with n-3 docosapentaenoic acid and eicosapentaenoic acid. 2016 FASEB J. pmid:27461565
Primdahl KG et al. Synthesis of 13(R)-Hydroxy-7Z,10Z,13R,14E,16Z,19Z Docosapentaenoic Acid (13R-HDPA) and Its Biosynthetic Conversion to the 13-Series Resolvins. 2016 J. Nat. Prod. pmid:27704804
Harris M et al. Membrane Disordering by Eicosapentaenoic Acid in B Lymphomas Is Reduced by Elongation to Docosapentaenoic Acid as Revealed with Solid-State Nuclear Magnetic Resonance Spectroscopy of Model Membranes. 2016 J. Nutr. pmid:27306897
Yoshida S et al. Treatment with DHA/EPA ameliorates atopic dermatitis-like skin disease by blocking LTB4 production. 2016 J. Med. Invest. pmid:27644556
Kuhnt K et al. Consumption of echium oil increases EPA and DPA in blood fractions more efficiently compared to linseed oil in humans. 2016 Lipids Health Dis pmid:26892399
Qin X et al. Brown but not white adipose cells synthesize omega-3 docosahexaenoic acid in culture. 2016 Prostaglandins Leukot. Essent. Fatty Acids pmid:26802938
Jo YY et al. Resolvin E1 Inhibits Substance P-Induced Potentiation of TRPV1 in Primary Sensory Neurons. 2016 Mediators Inflamm. pmid:27738388
Lee CT et al. Resolvin E1 Reverses Experimental Periodontitis and Dysbiosis. 2016 J. Immunol. pmid:27543615
Cholkar K et al. Topical delivery of aqueous micellar resolvin E1 analog (RX-10045). 2016 Int J Pharm pmid:26706439
Varrella S et al. First Morphological and Molecular Evidence of the Negative Impact of Diatom-Derived Hydroxyacids on the Sea Urchin Paracentrotus lividus. 2016 Toxicol. Sci. pmid:26984781
Medema S et al. Levels of Red Blood Cell Fatty Acids in Patients With Psychosis, Their Unaffected Siblings, and Healthy Controls. 2016 Schizophr Bull pmid:26385764
Elorinne AL et al. Food and Nutrient Intake and Nutritional Status of Finnish Vegans and Non-Vegetarians. 2016 PLoS ONE pmid:26840251
Kjær MA et al. Regulation of the Omega-3 Fatty Acid Biosynthetic Pathway in Atlantic Salmon Hepatocytes. 2016 PLoS ONE pmid:27973547
Wolters M et al. Associations of Whole Blood n-3 and n-6 Polyunsaturated Fatty Acids with Blood Pressure in Children and Adolescents - Results from the IDEFICS/I.Family Cohort. 2016 PLoS ONE pmid:27806134
Mao JT et al. Grape Seed Procyanidin Extract Mediates Antineoplastic Effects against Lung Cancer via Modulations of Prostacyclin and 15-HETE Eicosanoid Pathways. 2016 Cancer Prev Res (Phila) pmid:27658889
Ballantyne CM et al. Icosapent ethyl (eicosapentaenoic acid ethyl ester): Effects on remnant-like particle cholesterol from the MARINE and ANCHOR studies. 2016 Atherosclerosis pmid:27596132
Devassy JG et al. Omega-3 Polyunsaturated Fatty Acids and Oxylipins in Neuroinflammation and Management of Alzheimer Disease. 2016 Adv Nutr pmid:27633106
Moeinzadeh F et al. Effects of Omega-3 Fatty Acid Supplementation on Serum Biomarkers, Inflammatory Agents, and Quality of Life of Patients on Hemodialysis. 2016 Iran J Kidney Dis pmid:27903997
Luo T et al. Consumption of Walnuts in Combination with Other Whole Foods Produces Physiologic, Metabolic, and Gene Expression Changes in Obese C57BL/6J High-Fat-Fed Male Mice. 2016 J. Nutr. pmid:27489005
Shi H et al. Application of a delta-6 desaturase with α-linolenic acid preference on eicosapentaenoic acid production in Mortierella alpina. 2016 Microb. Cell Fact. pmid:27364006
Metherel AH et al. Whole-body DHA synthesis-secretion kinetics from plasma eicosapentaenoic acid and alpha-linolenic acid in the free-living rat. 2016 Biochim. Biophys. Acta pmid:27263420
Salic K et al. Resolvin E1 attenuates atherosclerosis in absence of cholesterol-lowering effects and on top of atorvastatin. 2016 Atherosclerosis pmid:27236706
Arnold WR et al. Asymmetric Binding and Metabolism of Polyunsaturated Fatty Acids (PUFAs) by CYP2J2 Epoxygenase. 2016 Biochemistry pmid:27992998
Minihane AM Impact of Genotype on EPA and DHA Status and Responsiveness to Increased Intakes. 2016 Nutrients pmid:26950146
Zhao Z et al. The Association of Fatty Acid Levels and Gleason Grade among Men Undergoing Radical Prostatectomy. 2016 PLoS ONE pmid:27880795
Heskey CE et al. Adipose tissue α-linolenic acid is inversely associated with insulin resistance in adults. 2016 Am. J. Clin. Nutr. pmid:26912497
Mason RP et al. Eicosapentaenoic acid reduces membrane fluidity, inhibits cholesterol domain formation, and normalizes bilayer width in atherosclerotic-like model membranes. 2016 Biochim. Biophys. Acta pmid:27718370
Kamata R et al. EPA Prevents the Development of Abdominal Aortic Aneurysms through Gpr-120/Ffar-4. 2016 PLoS ONE pmid:27764222
Cinelli G et al. Influence of Maternal Obesity and Gestational Weight Gain on Maternal and Foetal Lipid Profile. 2016 Nutrients pmid:27314385
McNamara RK and Welge JA Meta-analysis of erythrocyte polyunsaturated fatty acid biostatus in bipolar disorder. 2016 Bipolar Disord pmid:27087497
Barden A et al. n-3 Fatty Acid Supplementation and Leukocyte Telomere Length in Patients with Chronic Kidney Disease. 2016 Nutrients pmid:27007392
Gharekhani A et al. Potential Effects of Omega-3 Fatty Acids on Insulin Resistance and Lipid Profile in Maintenance Hemodialysis Patients: a Randomized Placebo-Controlled Trial. 2016 Iran J Kidney Dis pmid:27721230
Midtbø LK et al. Intake of farmed Atlantic salmon fed soybean oil increases hepatic levels of arachidonic acid-derived oxylipins and ceramides in mice. 2015 J. Nutr. Biochem. pmid:25776459
Shomonov-Wagner L et al. Alpha linolenic acid in maternal diet halts the lipid disarray due to saturated fatty acids in the liver of mice offspring at weaning. 2015 Lipids Health Dis pmid:25889505
Cespedes E et al. Adipose tissue n-3 fatty acids and metabolic syndrome. 2015 Eur J Clin Nutr pmid:25097001
Marinho GS et al. Lipids and Composition of Fatty Acids of Saccharina latissima Cultivated Year-Round in Integrated Multi-Trophic Aquaculture. 2015 Mar Drugs pmid:26184241
Keim SA and Branum AM Dietary intake of polyunsaturated fatty acids and fish among US children 12-60 months of age. 2015 Matern Child Nutr pmid:24034437
Barbour SE et al. Group VIA Phospholipase A2 (iPLA2β) Modulates Bcl-x 5'-Splice Site Selection and Suppresses Anti-apoptotic Bcl-x(L) in β-Cells. 2015 J. Biol. Chem. pmid:25762722
Amminger GP et al. Predictors of treatment response in young people at ultra-high risk for psychosis who received long-chain omega-3 fatty acids. 2015 Transl Psychiatry pmid:25585167
Reinders I et al. Plasma phospholipid PUFAs are associated with greater muscle and knee extension strength but not with changes in muscle parameters in older adults. 2015 J. Nutr. pmid:25355842
Ercan S et al. Induction of omega 6 inflammatory pathway by sodium metabisulfite in rat liver and its attenuation by ghrelin. 2015 Lipids Health Dis pmid:25889219
Talvas J et al. Immunonutrition stimulates immune functions and antioxidant defense capacities of leukocytes in radiochemotherapy-treated head & neck and esophageal cancer patients: A double-blind randomized clinical trial. 2015 Clin Nutr pmid:25575640
Braeckman RA et al. Effect of concomitant icosapent ethyl (eicosapentaenoic acid ethyl ester) on the pharmacokinetics of atorvastatin. 2015 Clin Drug Investig pmid:25471740
Maciejewska D et al. Fatty acid changes help to better understand regression of nonalcoholic fatty liver disease. 2015 World J. Gastroenterol. pmid:25574105
Linhartova P and Sampels S Combined incubation of cadmium, docosahexaenoic and eicosapentaenoic acid results in increased uptake of cadmium and elevated docosapentaenoic acid content in hepatocytes in vitro. 2015 Lipids Health Dis pmid:26627047
Holen E et al. Combining eicosapentaenoic acid, decosahexaenoic acid and arachidonic acid, using a fully crossed design, affect gene expression and eicosanoid secretion in salmon head kidney cells in vitro. 2015 Fish Shellfish Immunol. pmid:26003739
Morin C et al. Eicosapentaenoic acid and docosapentaenoic acid monoglycerides are more potent than docosahexaenoic acid monoglyceride to resolve inflammation in a rheumatoid arthritis model. 2015 Arthritis Res. Ther. pmid:26022389
Lim JY et al. Biological Roles of Resolvins and Related Substances in the Resolution of Pain. 2015 Biomed Res Int pmid:26339646
Chen SJ et al. Incorporation of eicosatrienoic acid exerts mild anti-inflammatory properties in murine RAW264.7 cells. 2015 Inflammation pmid:24993153
Hasturk H et al. Resolvin E1 (RvE1) Attenuates Atherosclerotic Plaque Formation in Diet and Inflammation-Induced Atherogenesis. 2015 Arterioscler. Thromb. Vasc. Biol. pmid:25792445
Schwager J et al. ω-3 PUFAs and Resveratrol Differently Modulate Acute and Chronic Inflammatory Processes. 2015 Biomed Res Int pmid:26301248
Harrison JL et al. Resolvins AT-D1 and E1 differentially impact functional outcome, post-traumatic sleep, and microglial activation following diffuse brain injury in the mouse. 2015 Brain Behav. Immun. pmid:25585137
Katakura M et al. Chronic Arachidonic Acid Administration Decreases Docosahexaenoic Acid- and Eicosapentaenoic Acid-Derived Metabolites in Kidneys of Aged Rats. 2015 PLoS ONE pmid:26485038
Wijendran V et al. Long-chain polyunsaturated fatty acids attenuate the IL-1β-induced proinflammatory response in human fetal intestinal epithelial cells. 2015 Pediatr. Res. pmid:26270575
Shi H et al. Molecular mechanism of substrate specificity for delta 6 desaturase from Mortierella alpina and Micromonas pusilla. 2015 J. Lipid Res. pmid:26486975
Hieda K et al. Pharmacological effect of functional foods with a hypotensive action. 2015 Nippon Yakurigaku Zasshi pmid:26165340
Kawakami Y et al. Flaxseed oil intake reduces serum small dense low-density lipoprotein concentrations in Japanese men: a randomized, double blind, crossover study. 2015 Nutr J pmid:25896182