EPA

Epa is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 19347 references associated with EPA in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for EPA

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with EPA

MeSH term MeSH ID Detail
Tuberculosis D014376 20 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Sarcoma, Experimental D012513 13 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Hyperglycemia D006943 21 associated lipids
Per page 10 20 50 100 | Total 140

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with EPA

Download all related citations
Per page 10 20 50 100 | Total 4880
Authors Title Published Journal PubMed Link
Mori TA Dietary n-3 PUFA and CVD: a review of the evidence. 2014 Proc Nutr Soc pmid:24119287
Fernández-González R et al. Decontamination solutions for polychlorinated biphenyls (PCBs) in raw fish oils from environmentally contaminated sea fishes. 2014 Sci. Total Environ. pmid:24095964
Amiano P et al. Intake of total omega-3 fatty acids, eicosapentaenoic acid and docosahexaenoic acid and risk of coronary heart disease in the Spanish EPIC cohort study. 2014 Nutr Metab Cardiovasc Dis pmid:24360762
Fleming JA and Kris-Etherton PM The evidence for α-linolenic acid and cardiovascular disease benefits: Comparisons with eicosapentaenoic acid and docosahexaenoic acid. 2014 Adv Nutr pmid:25398754
Schuster GU et al. Dietary long-chain omega-3 fatty acids do not diminish eosinophilic pulmonary inflammation in mice. 2014 Am. J. Respir. Cell Mol. Biol. pmid:24134486
De Mel D and Suphioglu C Fishy business: effect of omega-3 fatty acids on zinc transporters and free zinc availability in human neuronal cells. 2014 Nutrients pmid:25195602
Browning LM et al. Compared with daily, weekly n-3 PUFA intake affects the incorporation of eicosapentaenoic acid and docosahexaenoic acid into platelets and mononuclear cells in humans. 2014 J. Nutr. pmid:24647395
Hoogeveen EK et al. Effect of omega-3 fatty acids on kidney function after myocardial infarction: the Alpha Omega Trial. 2014 Clin J Am Soc Nephrol pmid:25104273
Arnardottir HH et al. Aging delays resolution of acute inflammation in mice: reprogramming the host response with novel nano-proresolving medicines. 2014 J. Immunol. pmid:25217168
Bremer AA et al. Fish oil supplementation ameliorates fructose-induced hypertriglyceridemia and insulin resistance in adult male rhesus macaques. 2014 J. Nutr. pmid:24108131
Papanikolaou Y et al. U.S. adults are not meeting recommended levels for fish and omega-3 fatty acid intake: results of an analysis using observational data from NHANES 2003-2008. 2014 Nutr J pmid:24694001
Jung JY et al. Effect of dietary supplementation with omega-3 fatty acid and gamma-linolenic acid on acne vulgaris: a randomised, double-blind, controlled trial. 2014 Acta Derm. Venereol. pmid:24553997
Wu FJ et al. The protective effect of eicosapentaenoic acid-enriched phospholipids from sea cucumber Cucumaria frondosa on oxidative stress in PC12 cells and SAMP8 mice. 2014 Neurochem. Int. pmid:24231470
Portillo-Reyes V et al. Clinical significance of neuropsychological improvement after supplementation with omega-3 in 8-12 years old malnourished Mexican children: a randomized, double-blind, placebo and treatment clinical trial. 2014 Res Dev Disabil pmid:24508294
Li J et al. Fish oil and fenofibrate prevented phosphorylation-dependent hepatic sortilin 1 degradation in Western diet-fed mice. 2014 J. Biol. Chem. pmid:24986865
Marklund M et al. A dietary biomarker approach captures compliance and cardiometabolic effects of a healthy Nordic diet in individuals with metabolic syndrome. 2014 J. Nutr. pmid:25080537
Purushothaman D et al. Flaxseed oil supplementation alters the expression of inflammatory-related genes in dogs. 2014 Genet. Mol. Res. pmid:25078588
Evans SJ et al. Dietary intake and plasma metabolomic analysis of polyunsaturated fatty acids in bipolar subjects reveal dysregulation of linoleic acid metabolism. 2014 J Psychiatr Res pmid:24953860
Maffei S et al. Effects of ω-3 PUFAs supplementation on myocardial function and oxidative stress markers in typical Rett syndrome. 2014 Mediators Inflamm. pmid:24526821
Hu S et al. Eicosapentaenoic acid-enriched phosphatidylcholine isolated from Cucumaria frondosa exhibits anti-hyperglycemic effects via activating phosphoinositide 3-kinase/protein kinase B signal pathway. 2014 J. Biosci. Bioeng. pmid:24168893
Sanyal AJ et al. No significant effects of ethyl-eicosapentanoic acid on histologic features of nonalcoholic steatohepatitis in a phase 2 trial. 2014 Gastroenterology pmid:24818764
Moradi Sarabi M et al. Effect of eicosapentaenoic acid on the expression of ABCG1 gene in the human monocyte THP-1 cells. 2014 Acta Med Iran pmid:24901717
Endo J et al. 18-HEPE, an n-3 fatty acid metabolite released by macrophages, prevents pressure overload-induced maladaptive cardiac remodeling. 2014 J. Exp. Med. pmid:25049337
Castaldo RS A retrospective case series of the lipid effects of switching from omega-3 fatty acid ethyl esters to icosapent ethyl in hyperlipidemic patients. 2014 Postgrad Med pmid:24977343
Fukunaga K [The mechanism of airway hyperresponsiveness by lipid mediators]. 2014 Arerugi pmid:24953733
Takada K et al. Effects of eicosapentaenoic acid on platelet function in patients taking long-term aspirin following coronary stent implantation. 2014 Int Heart J pmid:24806387
Kitagawa Y et al. Gender differences in the ratio of eicosapentaenoic acid to arachidonic acid in an inland prefecture, Tochigi: Tochigi Ryomo EPA/AA Trial in Coronary Artery Disease (TREAT-CAD). 2014 Intern. Med. pmid:24492684
Aslan M et al. A pilot study investigating early postoperative changes of plasma polyunsaturated fatty acids after laparoscopic sleeve gastrectomy. 2014 Lipids Health Dis pmid:24694037
Santos S et al. Fatty acids derived from a food frequency questionnaire and measured in the erythrocyte membrane in relation to adiponectin and leptin concentrations. 2014 Eur J Clin Nutr pmid:24642786
Hsu HC et al. Eicosapentaenoic acid attenuated oxidative stress-induced cardiomyoblast apoptosis by activating adaptive autophagy. 2014 Eur J Nutr pmid:23887854
Camacho-Rodríguez J et al. A quantitative study of eicosapentaenoic acid (EPA) production by Nannochloropsis gaditana for aquaculture as a function of dilution rate, temperature and average irradiance. 2014 Appl. Microbiol. Biotechnol. pmid:24318007
Abiusi F et al. Growth, photosynthetic efficiency, and biochemical composition of Tetraselmis suecica F&M-M33 grown with LEDs of different colors. 2014 Biotechnol. Bioeng. pmid:23904253
Yuan D et al. Ancestral genetic complexity of arachidonic acid metabolism in Metazoa. 2014 Biochim. Biophys. Acta pmid:24801744
Sorensen LS et al. Randomized clinical trial of perioperative omega-3 fatty acid supplements in elective colorectal cancer surgery. 2014 Br J Surg pmid:24281905
Kim SH et al. Functional characterization of polyunsaturated fatty acid delta 6-desaturase and elongase genes from the black seabream (Acanthopagrus schlegelii). 2014 Cell Biochem. Biophys. pmid:24052399
Prostek A et al. The influence of EPA and DHA on markers of inflammation in 3T3-L1 cells at different stages of cellular maturation. 2014 Lipids Health Dis pmid:24387137
Nagao K et al. Comparison of the lipid-lowering effects of four different n-3 highly unsaturated fatty acids in HepG2 cells. 2014 J Oleo Sci pmid:25213447
Norris JM et al. Erythrocyte membrane docosapentaenoic acid levels are associated with islet autoimmunity: the Diabetes Autoimmunity Study in the Young. 2014 Diabetologia pmid:24240437
Nakagawa F et al. 4-Hydroxy hexenal derived from dietary n-3 polyunsaturated fatty acids induces anti-oxidative enzyme heme oxygenase-1 in multiple organs. 2014 Biochem. Biophys. Res. Commun. pmid:24361890
Wójcik C et al. Modulation of adipocyte differentiation by omega-3 polyunsaturated fatty acids involves the ubiquitin-proteasome system. 2014 J. Cell. Mol. Med. pmid:24834523
Yamanushi TT et al. Oral administration of eicosapentaenoic acid or docosahexaenoic acid modifies cardiac function and ameliorates congestive heart failure in male rats. 2014 J. Nutr. pmid:24523492
Meagher KA et al. Regarding macular xanthophylls and ω-3 long-chain polyunsaturated fatty acids in age-related macular degeneration. 2014 JAMA Ophthalmol pmid:24525935
Arnold C et al. Regarding macular xanthophylls and ω-3 long-chain polyunsaturated fatty acids in age-related macular degeneration--reply. 2014 JAMA Ophthalmol pmid:24525936
Ghasemi Fard S et al. Comparison of the bioavailability of docosapentaenoic acid (DPA, 22:5n-3) and eicosapentaenoic acid (EPA, 20:5n-3) in the rat. 2014 Prostaglandins Leukot. Essent. Fatty Acids pmid:24238887
Brasky TM et al. Associations of long-chain ω-3 fatty acids and fish intake with endometrial cancer risk in the VITamins And Lifestyle cohort. 2014 Am. J. Clin. Nutr. pmid:24500149
Petrie JR et al. Metabolic engineering Camelina sativa with fish oil-like levels of DHA. 2014 PLoS ONE pmid:24465476
Pavićević ID et al. Fatty acids binding to human serum albumin: Changes of reactivity and glycation level of Cysteine-34 free thiol group with methylglyoxal. 2014 Chem. Biol. Interact. pmid:25451573
Kabeya N et al. Modification of the n-3 HUFA biosynthetic pathway by transgenesis in a marine teleost, nibe croaker. 2014 J. Biotechnol. pmid:24389067
Torricelli AA et al. Resolvin E1 analog RX-10045 0.1% reduces corneal stromal haze in rabbits when applied topically after PRK. 2014 Mol. Vis. pmid:25558174
Taltavull N et al. Eicosapentaenoic acid/docosahexaenoic acid 1:1 ratio improves histological alterations in obese rats with metabolic syndrome. 2014 Lipids Health Dis pmid:24512213
Gyurko R and Van Dyke TE The role of polyunsaturated ω-3 fatty acid eicosapentaenoic acid-derived resolvin E1 (RvE1) in bone preservation. 2014 Crit. Rev. Immunol. pmid:24941160
Gautam M et al. Importance of fatty acid compositions in patients with peripheral arterial disease. 2014 PLoS ONE pmid:25191963
O'Callaghan N et al. Telomere shortening in elderly individuals with mild cognitive impairment may be attenuated with ω-3 fatty acid supplementation: a randomized controlled pilot study. 2014 Nutrition pmid:24342530
Kitessa SM et al. DHA-containing oilseed: a timely solution for the sustainability issues surrounding fish oil sources of the health-benefitting long-chain omega-3 oils. 2014 Nutrients pmid:24858407
Røsjø E et al. Increasing serum levels of vitamin A, D and E are associated with alterations of different inflammation markers in patients with multiple sclerosis. 2014 J. Neuroimmunol. pmid:24713402
Kalinić D et al. Eicosapentaenoic acid in serum lipids could be inversely correlated with severity of clinical symptomatology in Croatian war veterans with posttraumatic stress disorder. 2014 Croat. Med. J. pmid:24577824
Yasuda M et al. Fatty acids are novel nutrient factors to regulate mTORC1 lysosomal localization and apoptosis in podocytes. 2014 Biochim. Biophys. Acta pmid:24726883
Dendelé B et al. Protective action of n-3 fatty acids on benzo[a]pyrene-induced apoptosis through the plasma membrane remodeling-dependent NHE1 pathway. 2014 Chem. Biol. Interact. pmid:24246761
O'Sullivan A et al. Habitual diets rich in dark-green vegetables are associated with an increased response to ω-3 fatty acid supplementation in Americans of African ancestry. 2014 J. Nutr. pmid:24259553
Yang Y et al. Lipidomic analyses of female mice lacking hepatic lipase and endothelial lipase indicate selective modulation of plasma lipid species. 2014 Lipids pmid:24777581
Bauer I et al. Does omega-3 fatty acid supplementation enhance neural efficiency? A review of the literature. 2014 Hum Psychopharmacol pmid:24285504
Höper AC et al. Wax esters from the marine copepod Calanus finmarchicus reduce diet-induced obesity and obesity-related metabolic disorders in mice. 2014 J. Nutr. pmid:24285691
DiNicolantonio JJ et al. A higher dietary ratio of long-chain omega-3 to total omega-6 fatty acids for prevention of COX-2-dependent adenocarcinomas. 2014 Nutr Cancer pmid:25356937
Crowe FL et al. Circulating fatty acids and prostate cancer risk: individual participant meta-analysis of prospective studies. 2014 J. Natl. Cancer Inst. pmid:25210201
Hutchins-Wiese HL et al. High-dose eicosapentaenoic acid and docosahexaenoic acid supplementation reduces bone resorption in postmenopausal breast cancer survivors on aromatase inhibitors: a pilot study. 2014 Nutr Cancer pmid:24274259
Yao QH et al. ω-3 polyunsaturated fatty acids inhibit the proliferation of the lung adenocarcinoma cell line A549 in vitro. 2014 Mol Med Rep pmid:24276408
Hixson SM et al. Changes in tissue lipid and fatty acid composition of farmed rainbow trout in response to dietary camelina oil as a replacement of fish oil. 2014 Lipids pmid:24264359
de Waal H et al. The effect of souvenaid on functional brain network organisation in patients with mild Alzheimer's disease: a randomised controlled study. 2014 PLoS ONE pmid:24475144
James MJ et al. Pitfalls in the use of randomised controlled trials for fish oil studies with cardiac patients. 2014 Br. J. Nutr. pmid:24933212
Purcell R et al. High-fat meals rich in EPA plus DHA compared with DHA only have differential effects on postprandial lipemia and plasma 8-isoprostane F2α concentrations relative to a control high-oleic acid meal: a randomized controlled trial. 2014 Am. J. Clin. Nutr. pmid:25099540
Harris WS et al. Comparative effects of an acute dose of fish oil on omega-3 fatty acid levels in red blood cells versus plasma: implications for clinical utility. 2013 Sep-Oct J Clin Lipidol pmid:24079284
Tatsuno I et al. Long-term safety and efficacy of TAK-085 in Japanese subjects with hypertriglyceridemia undergoing lifestyle modification: the omega-3 fatty acids randomized long-term (ORL) study. 2013 Nov-Dec J Clin Lipidol pmid:24314359
Igarashi M et al. Kinetics of eicosapentaenoic acid in brain, heart and liver of conscious rats fed a high n-3 PUFA containing diet. 2013 Nov-Dec Prostaglandins Leukot. Essent. Fatty Acids pmid:24209500
Fenton JI et al. Immunomodulation by dietary long chain omega-3 fatty acids and the potential for adverse health outcomes. 2013 Nov-Dec Prostaglandins Leukot. Essent. Fatty Acids pmid:24183073
Tatsuno I et al. Efficacy and safety of TAK-085 compared with eicosapentaenoic acid in Japanese subjects with hypertriglyceridemia undergoing lifestyle modification: the omega-3 fatty acids randomized double-blind (ORD) study. 2013 May-Jun J Clin Lipidol pmid:23725919
Nishimura RY et al. Breast milk fatty acid composition of women living far from the coastal area in Brazil. 2013 May-Jun J Pediatr (Rio J) pmid:23669215
Zajdel A et al. Polyunsaturated fatty acids inhibit melanoma cell growth in vitro. 2013 Mar-Apr Acta Pol Pharm pmid:23614295
Kanat O et al. Comparison of three different treatment modalities in the management of cancer cachexia. 2013 Mar-Apr Tumori pmid:23748819
Piñeiro-Corrales G et al. [Role of omega-3 fatty acids in cardiovascular disease prevention]. 2013 Jan-Feb Nutr Hosp pmid:23808424
Gelsomino G et al. Omega 3 fatty acids chemosensitize multidrug resistant colon cancer cells by down-regulating cholesterol synthesis and altering detergent resistant membranes composition. 2013 Mol. Cancer pmid:24225025
Cederholm T et al. ω-3 fatty acids in the prevention of cognitive decline in humans. 2013 Adv Nutr pmid:24228198
Jansen D et al. Effects of specific multi-nutrient enriched diets on cerebral metabolism, cognition and neuropathology in AβPPswe-PS1dE9 mice. 2013 PLoS ONE pmid:24086523
Faber J et al. Rapid EPA and DHA incorporation and reduced PGE2 levels after one week intervention with a medical food in cancer patients receiving radiotherapy, a randomized trial. 2013 Clin Nutr pmid:23123043
Ríos SD et al. Lipid extraction methods from microalgal biomass harvested by two different paths: screening studies toward biodiesel production. 2013 Bioresour. Technol. pmid:23434816
Momiyama Y Association between serum omega-3 to omega-6 polyunsaturated fatty acid ratio and cardiovascular events in a general Japanese population. 2013 Atherosclerosis pmid:24267240
Chen CT et al. The low levels of eicosapentaenoic acid in rat brain phospholipids are maintained via multiple redundant mechanisms. 2013 J. Lipid Res. pmid:23836105
Romero VC et al. Developmental programming for allergy: a secondary analysis of the Mothers, Omega-3, and Mental Health Study. 2013 Am. J. Obstet. Gynecol. pmid:23531329
Jacobs BR et al. Nutritional immunomodulation in critically ill children with acute lung injury: feasibility and impact on circulating biomarkers. 2013 Pediatr Crit Care Med pmid:23295853
Lundström SL et al. Lipid mediator serum profiles in asthmatics significantly shift following dietary supplementation with omega-3 fatty acids. 2013 Mol Nutr Food Res pmid:23824870
Lohner S et al. Lower n-3 long-chain polyunsaturated fatty acid values in patients with phenylketonuria: a systematic review and meta-analysis. 2013 Nutr Res pmid:23827125
Ramkumar HL et al. Nutrient supplementation with n3 polyunsaturated fatty acids, lutein, and zeaxanthin decrease A2E accumulation and VEGF expression in the retinas of Ccl2/Cx3cr1-deficient mice on Crb1rd8 background. 2013 J. Nutr. pmid:23677863
Ballantyne CM et al. Authors' reply. 2013 Am. J. Cardiol. pmid:23317532
Nobre ME et al. Eicosapentaenoic acid and docosahexaenoic acid exert anti-inflammatory and antinociceptive effects in rodents at low doses. 2013 Nutr Res pmid:23684444
Moriyama T et al. Effects of combination therapy with renin-angiotensin system inhibitors and eicosapentaenoic acid on IgA nephropathy. 2013 Intern. Med. pmid:23318848
Chien KL et al. Comparison of predictive performance of various fatty acids for the risk of cardiovascular disease events and all-cause deaths in a community-based cohort. 2013 Atherosclerosis pmid:23958266
Reinders I et al. Associations of serum n-3 and n-6 polyunsaturated fatty acids with echocardiographic measures among older adults: the Hoorn Study. 2013 Eur J Clin Nutr pmid:24084512
Metherel AH et al. EPA and DHA levels in whole blood decrease more rapidly when stored at -20 °C as compared with room temperature, 4 and -75 °C. 2013 Lipids pmid:23949919
Matsuoka Y et al. Tachikawa project for prevention of posttraumatic stress disorder with polyunsaturated fatty acid (TPOP): study protocol for a randomized controlled trial. 2013 BMC Psychiatry pmid:23289548
Phang M et al. Eicosapentaenoic and docosahexaenoic acid supplementations reduce platelet aggregation and hemostatic markers differentially in men and women. 2013 J. Nutr. pmid:23390192
Nikolakopoulou Z et al. The induction of apoptosis in pre-malignant keratinocytes by omega-3 polyunsaturated fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) is inhibited by albumin. 2013 Toxicol. Lett. pmid:23391486