EPA

Epa is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 19347 references associated with EPA in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for EPA

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with EPA

MeSH term MeSH ID Detail
Tuberculosis D014376 20 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Sarcoma, Experimental D012513 13 associated lipids
Graft Occlusion, Vascular D006083 11 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Hyperglycemia D006943 21 associated lipids
Per page 10 20 50 100 | Total 140

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with EPA

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Per page 10 20 50 100 | Total 4880
Authors Title Published Journal PubMed Link
Vyncke KE et al. Intake and serum profile of fatty acids are weakly correlated with global dietary quality in European adolescents. 2013 Nutrition pmid:23312763
Ðurendić-Brenesel M et al. Hypolipidemic and antioxidant effects of buckwheat leaf and flower mixture in hyperlipidemic rats. 2013 Bosn J Basic Med Sci pmid:23725506
Chen F et al. Fish oil attenuates liver injury caused by LPS in weaned pigs associated with inhibition of TLR4 and nucleotide-binding oligomerization domain protein signaling pathways. 2013 Innate Immun pmid:23339927
Amminger GP et al. Omega-3 fatty acid supplementation in adolescents with borderline personality disorder and ultra-high risk criteria for psychosis: a post hoc subgroup analysis of a double-blind, randomized controlled trial. 2013 Can J Psychiatry pmid:23870722
Lefils-Lacourtablaise J et al. The eicosapentaenoic acid metabolite 15-deoxy-δ(12,14)-prostaglandin J3 increases adiponectin secretion by adipocytes partly via a PPARγ-dependent mechanism. 2013 PLoS ONE pmid:23734181
Offman E et al. Steady-state bioavailability of prescription omega-3 on a low-fat diet is significantly improved with a free fatty acid formulation compared with an ethyl ester formulation: the ECLIPSE II study. 2013 Vasc Health Risk Manag pmid:24124374
Simon MC et al. Fatty acids modulate cytokine and chemokine secretion of stimulated human whole blood cultures in diabetes. 2013 Clin. Exp. Immunol. pmid:23600826
Ikeya Y et al. Comparison of eicosapentaenoic acid concentrations in plasma between patients with ischemic stroke and control subjects. 2013 Nutrition pmid:23010418
Xu J et al. Expression of a type 2 diacylglycerol acyltransferase from Thalassiosira pseudonana in yeast leads to incorporation of docosahexaenoic acid β-oxidation intermediates into triacylglycerol. 2013 FEBS J. pmid:24128189
Bays HE et al. Icosapent ethyl, a pure ethyl ester of eicosapentaenoic acid: effects on circulating markers of inflammation from the MARINE and ANCHOR studies. 2013 Am J Cardiovasc Drugs pmid:23325450
Furne M et al. Cytokine gene expression and prostaglandin production in head kidney leukocytes isolated from Atlantic cod (Gadus morhua) added different levels of arachidonic acid and eicosapentaenoic acid. 2013 Fish Shellfish Immunol. pmid:23291252
Casey JM et al. Effect of stearidonic acid-enriched soybean oil on fatty acid profile and metabolic parameters in lean and obese Zucker rats. 2013 Lipids Health Dis pmid:24139088
Wynn JP Taking the fish out of fish oil. 2013 Nat. Biotechnol. pmid:23929348
Lee LK et al. The role of long chain omega-3 polyunsaturated fatty acids in reducing lipid peroxidation among elderly patients with mild cognitive impairment: a case-control study. 2013 J. Nutr. Biochem. pmid:22898566
Nozue T et al. Effects of statins on serum n-3 to n-6 polyunsaturated fatty acid ratios in patients with coronary artery disease. 2013 J. Cardiovasc. Pharmacol. Ther. pmid:23324995
Tsuboi H et al. Associations of depressive symptoms with serum proportions of palmitic and arachidonic acids, and α-tocopherol effects among male population--a preliminary study. 2013 Clin Nutr pmid:22901744
Larson MK et al. Exogenous modification of platelet membranes with the omega-3 fatty acids EPA and DHA reduces platelet procoagulant activity and thrombus formation. 2013 Am. J. Physiol., Cell Physiol. pmid:23174566
Song Y et al. Polyunsaturated fatty acid relatively decreases cholesterol content in THP-1 macrophage-derived foam cell: partly correlates with expression profile of CIDE and PAT members. 2013 Lipids Health Dis pmid:23879935
Zong G et al. Effects of flaxseed supplementation on erythrocyte fatty acids and multiple cardiometabolic biomarkers among Chinese with risk factors of metabolic syndrome. 2013 Eur J Nutr pmid:23179200
Poudyal H et al. Effects of ALA, EPA and DHA in high-carbohydrate, high-fat diet-induced metabolic syndrome in rats. 2013 J. Nutr. Biochem. pmid:23026492
Cartiff SE et al. Eicosapentaenoic and docosahexaenoic acids increase insulin sensitivity in growing steers. 2013 J. Anim. Sci. pmid:23463554
Kataoka Y et al. Epanova(®) and hypertriglyceridemia: pharmacological mechanisms and clinical efficacy. 2013 Future Cardiol pmid:23463969
Mocking RJ et al. Relationship between the hypothalamic-pituitary-adrenal-axis and fatty acid metabolism in recurrent depression. 2013 Psychoneuroendocrinology pmid:23465556
Hara M et al. Low levels of serum n-3 polyunsaturated fatty acids are associated with worse heart failure-free survival in patients after acute myocardial infarction. 2013 Circ. J. pmid:23047296
Dobson EP et al. Controlled formation of mono- and dihydroxy-resolvins from EPA and DHA using soybean 15-lipoxygenase. 2013 J. Lipid Res. pmid:23471029
van den Elsen LW et al. n-3 Long-chain PUFA reduce allergy-related mediator release by human mast cells in vitro via inhibition of reactive oxygen species. 2013 Br. J. Nutr. pmid:23021516
Skilton MR et al. High intake of dietary long-chain ω-3 fatty acids is associated with lower blood pressure in children born with low birth weight: NHANES 2003-2008. 2013 Hypertension pmid:23460284
MacIntosh BA et al. Low-n-6 and low-n-6 plus high-n-3 diets for use in clinical research. 2013 Br. J. Nutr. pmid:23328113
Williams JJ et al. N-3 fatty acid rich triglyceride emulsions are neuroprotective after cerebral hypoxic-ischemic injury in neonatal mice. 2013 PLoS ONE pmid:23437099
Kamolrat T and Gray SR The effect of eicosapentaenoic and docosahexaenoic acid on protein synthesis and breakdown in murine C2C12 myotubes. 2013 Biochem. Biophys. Res. Commun. pmid:23438435
Carey AN et al. The ability of walnut extract and fatty acids to protect against the deleterious effects of oxidative stress and inflammation in hippocampal cells. 2013 Nutr Neurosci pmid:23321679
Davidson J et al. Eicosapentaenoic acid suppression of systemic inflammatory responses and inverse up-regulation of 15-deoxyΔ(12,14) prostaglandin J2 production. 2013 Br. J. Pharmacol. pmid:23586396
Mozaffari-Khosravi H et al. Eicosapentaenoic acid versus docosahexaenoic acid in mild-to-moderate depression: a randomized, double-blind, placebo-controlled trial. 2013 Eur Neuropsychopharmacol pmid:22910528
Aktas BH et al. Small-Molecule targeting of translation initiation for cancer therapy. 2013 Oncotarget pmid:24091475
Yamaguchi M et al. Consumption of seafood, serum liver enzymes, and blood levels of PFOS and PFOA in the Japanese population. 2013 J Occup Health pmid:23574777
Arem H et al. Omega-3 and omega-6 fatty acid intakes and endometrial cancer risk in a population-based case-control study. 2013 Eur J Nutr pmid:22915050
Randall KM et al. Effects of dietary supplementation of coriander oil, in canola oil diets, on the metabolism of [1-(14)C] 18:3n-3 and [1-(14)C] 18:2n-6 in rainbow trout hepatocytes. 2013 Comp. Biochem. Physiol. B, Biochem. Mol. Biol. pmid:23867781
Rahman MM et al. DHA is a more potent inhibitor of breast cancer metastasis to bone and related osteolysis than EPA. 2013 Breast Cancer Res. Treat. pmid:24062211
Xue Z et al. Production of omega-3 eicosapentaenoic acid by metabolic engineering of Yarrowia lipolytica. 2013 Nat. Biotechnol. pmid:23873085
Miller E et al. A short-term n-3 DPA supplementation study in humans. 2013 Eur J Nutr pmid:22729967
Safarinejad MR et al. Effects of EPA, γ-linolenic acid or coenzyme Q10 on serum prostate-specific antigen levels: a randomised, double-blind trial. 2013 Br. J. Nutr. pmid:23199523
Vigerust NF et al. Krill oil versus fish oil in modulation of inflammation and lipid metabolism in mice transgenic for TNF-α. 2013 Eur J Nutr pmid:22923017
Orozco-Solano MI et al. Analysis of esterified and nonesterified fatty acids in serum from obese individuals after intake of breakfasts prepared with oils heated at frying temperature. 2013 Anal Bioanal Chem pmid:23657457
Pirman DA et al. Changes in cancer cell metabolism revealed by direct sample analysis with MALDI mass spectrometry. 2013 PLoS ONE pmid:23658609
Cohen DA et al. Impact of two pulmonary enteral formulations on nutritional indices and outcomes. 2013 J Hum Nutr Diet pmid:23189938
Watanabe S and Tsuneyama K Eicosapentaenoic acid attenuates hepatic accumulation of cholesterol esters but aggravates liver injury and inflammation in mice fed a cholate-supplemented high-fat diet. 2013 J Toxicol Sci pmid:23665937
Fukui M et al. EPA, an omega-3 fatty acid, induces apoptosis in human pancreatic cancer cells: role of ROS accumulation, caspase-8 activation, and autophagy induction. 2013 J. Cell. Biochem. pmid:22903547
Isobe Y et al. Stereochemical assignment and anti-inflammatory properties of the omega-3 lipid mediator resolvin E3. 2013 J. Biochem. pmid:23293324
Tu WC et al. Correlations between blood and tissue omega-3 LCPUFA status following dietary ALA intervention in rats. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:22521090
Linderborg KM et al. Postprandial metabolism of docosapentaenoic acid (DPA, 22:5n-3) and eicosapentaenoic acid (EPA, 20:5n-3) in humans. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:23433939
Damsgaard CT et al. n-3 PUFA status in school children is associated with beneficial lipid profile, reduced physical activity and increased blood pressure in boys. 2013 Br. J. Nutr. pmid:23591057
Rahmawaty S et al. Dietary intake and food sources of EPA, DPA and DHA in Australian children. 2013 Lipids pmid:23881381
Kiernan M et al. The effect of the in vitro supplementation of exogenous long-chain fatty acids on bovine sperm cell function. 2013 Reprod. Fertil. Dev. pmid:23036717
Tapsell LC et al. Foods, nutrients or whole diets: effects of targeting fish and LCn3PUFA consumption in a 12mo weight loss trial. 2013 BMC Public Health pmid:24369765
Iketani T et al. Effect of eicosapentaenoic acid on central systolic blood pressure. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:23246023
Muldoon MF et al. Concurrent physical activity modifies the association between n3 long-chain fatty acids and cardiometabolic risk in midlife adults. 2013 J. Nutr. pmid:23884386
Zhang R et al. Identification of a fatty acid ∆(6)-desaturase gene from the eicosapentaenoic acid-producing fungus Pythium splendens RBB-5. 2013 Biotechnol. Lett. pmid:23247564
Mocellin MC et al. Fish oil decreases C-reactive protein/albumin ratio improving nutritional prognosis and plasma fatty acid profile in colorectal cancer patients. 2013 Lipids pmid:23888317
Zhang J et al. Different intakes of n-3 fatty acids among pregnant women in 3 regions of China with contrasting dietary patterns are reflected in maternal but not in umbilical erythrocyte phosphatidylcholine fatty acid composition. 2013 Nutr Res pmid:23890350
Shiraishi M et al. Estimation of eicosapentaenoic acid and docosahexaenoic acid intakes in pregnant Japanese women without nausea by using a self-administered diet history questionnaire. 2013 Nutr Res pmid:23746563
Wu JH et al. Plasma phospholipid omega-3 fatty acids and incidence of postoperative atrial fibrillation in the OPERA trial. 2013 J Am Heart Assoc pmid:24145742
Tanaka M et al. The assessment of risk for gastrointestinal injury with anticoagulant and antiplatelet drugs: the possible beneficial effect of eicosapentaenoic Acid for the risk of gastrointestinal injury. 2013 Biol. Pharm. Bull. pmid:23207874
Fietkau R et al. A disease-specific enteral nutrition formula improves nutritional status and functional performance in patients with head and neck and esophageal cancer undergoing chemoradiotherapy: results of a randomized, controlled, multicenter trial. 2013 Cancer pmid:23765693
Weiss GA et al. High levels of anti-inflammatory and pro-resolving lipid mediators lipoxins and resolvins and declining docosahexaenoic acid levels in human milk during the first month of lactation. 2013 Lipids Health Dis pmid:23767972
Unoda K et al. Eicosapentaenoic acid (EPA) induces peroxisome proliferator-activated receptors and ameliorates experimental autoimmune encephalomyelitis. 2013 J. Neuroimmunol. pmid:23276800
Meyer BJ et al. Improvement of major depression is associated with increased erythrocyte DHA. 2013 Lipids pmid:23733443
Alhazzaa R et al. Bioconversion of α-linolenic acid into n-3 long-chain polyunsaturated fatty acid in hepatocytes and ad hoc cell culture optimisation. 2013 PLoS ONE pmid:24040040
Zawadzki M et al. Perna canaliculus lipid complex PCSO-524â„¢ demonstrated pain relief for osteoarthritis patients benchmarked against fish oil, a randomized trial, without placebo control. 2013 Mar Drugs pmid:23739042
Morel PC et al. Effect of lipid type on growth performance, meat quality and the content of long chain n-3 fatty acids in pork meat. 2013 Meat Sci. pmid:23739265
Liu Y et al. Fish oil increases muscle protein mass and modulates Akt/FOXO, TLR4, and NOD signaling in weanling piglets after lipopolysaccharide challenge. 2013 J. Nutr. pmid:23739309
Juman S et al. Effects of long-term oral administration of arachidonic acid and docosahexaenoic acid on the immune functions of young rats. 2013 Nutrients pmid:23760060
Laird BD et al. Dietary advice on Inuit traditional food use needs to balance benefits and risks of mercury, selenium, and n3 fatty acids. 2013 J. Nutr. pmid:23616502
Sala-Vila A et al. Eicosapentaenoic acid in serum phospholipids relates to a less atherogenic lipoprotein profile in subjects with familial hypercholesterolemia. 2013 J. Nutr. Biochem. pmid:23618530
Barber E et al. Comparative actions of omega-3 fatty acids on in-vitro lipid droplet formation. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:24012207
Lemke SL et al. Consumption of stearidonic acid-rich oil in foods increases red blood cell eicosapentaenoic acid. 2013 J Acad Nutr Diet pmid:23885702
Johnston DT et al. Red blood cell omega-3 fatty acid levels and neurocognitive performance in deployed U.S. Servicemembers. 2013 Nutr Neurosci pmid:22748167
Kawabata T et al. Influences of stearidonic acid-enriched soybean oil on the blood and organ biochemical parameters in rats. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:23219237
Nicholson T et al. The role of marine n-3 fatty acids in improving cardiovascular health: a review. 2013 Food Funct pmid:23325431
Flock MR et al. Immunometabolic role of long-chain omega-3 fatty acids in obesity-induced inflammation. 2013 Diabetes Metab. Res. Rev. pmid:23592441
Bertrand C et al. Effects of dietary eicosapentaenoic acid (EPA) supplementation in high-fat fed mice on lipid metabolism and apelin/APJ system in skeletal muscle. 2013 PLoS ONE pmid:24244380
Nelson SD and Munger MA Icosapent ethyl for treatment of elevated triglyceride levels. 2013 Ann Pharmacother pmid:24259598
Fu Y et al. The desaturase OPIN17 from Phytophthora infestans converts arachidonic acid to eicosapentaenoic acid in CHO cells. 2013 Appl. Biochem. Biotechnol. pmid:23912207
Porenta SR et al. Interaction of fatty acid genotype and diet on changes in colonic fatty acids in a Mediterranean diet intervention study. 2013 Cancer Prev Res (Phila) pmid:24022589
Gibson RA et al. Docosahexaenoic acid synthesis from alpha-linolenic acid is inhibited by diets high in polyunsaturated fatty acids. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:22515943
Mühlroth A et al. Pathways of lipid metabolism in marine algae, co-expression network, bottlenecks and candidate genes for enhanced production of EPA and DHA in species of Chromista. 2013 Mar Drugs pmid:24284429
Fogagnolo Mauricio A et al. Effects of fish oil containing eicosapentaenoic acid and docosahexaenoic acid on dystrophic mdx mice. 2013 Clin Nutr pmid:23218947
Wang D et al. Organochlorine pesticides in fish from Taihu Lake, China, and associated human health risk assessment. 2013 Ecotoxicol. Environ. Saf. pmid:24125867
Yee LD et al. The inhibition of early stages of HER-2/neu-mediated mammary carcinogenesis by dietary n-3 PUFAs. 2013 Mol Nutr Food Res pmid:23213007
Nikolakopoulou Z et al. Omega-3 polyunsaturated fatty acids selectively inhibit growth in neoplastic oral keratinocytes by differentially activating ERK1/2. 2013 Carcinogenesis pmid:23892603
Tomita T et al. High concentrations of omega-3 fatty acids are associated with the development of atrial fibrillation in the Japanese population. 2013 Heart Vessels pmid:22696184
Borghetti G et al. Tumor growth reduction is regulated at the gene level in Walker 256 tumor-bearing rats supplemented with fish oil rich in EPA and DHA. 2013 Braz. J. Med. Biol. Res. pmid:24036940
Innis SM et al. Long chain omega-3 fatty acids: micronutrients in disguise. 2013 Prostaglandins Leukot. Essent. Fatty Acids pmid:22709913
Jaudszus A et al. Evaluation of suppressive and pro-resolving effects of EPA and DHA in human primary monocytes and T-helper cells. 2013 J. Lipid Res. pmid:23349208
Babaahmadi Rezaei H et al. Compare the effect of eicosapentaenoic acid and oxidized low-density lipoprotein on the expression of CD36 and peroxisome proliferator-activated receptor gamma. 2013 Iran. Biomed. J. pmid:23567850
Oner G and Muderris II Efficacy of omega-3 in the treatment of polycystic ovary syndrome. 2013 J Obstet Gynaecol pmid:23550861
Gustafsson SB et al. Effects of cannabinoids and related fatty acids upon the viability of P19 embryonal carcinoma cells. 2013 Arch. Toxicol. pmid:23552853
McEwen BJ et al. Effects of omega-3 polyunsaturated fatty acids on platelet function in healthy subjects and subjects with cardiovascular disease. 2013 Semin. Thromb. Hemost. pmid:23329646
Turk HF et al. Inhibitory effects of omega-3 fatty acids on injury-induced epidermal growth factor receptor transactivation contribute to delayed wound healing. 2013 Am. J. Physiol., Cell Physiol. pmid:23426968
Lyons MR et al. Impact of sex on the heart's metabolic and functional responses to diabetic therapies. 2013 Am. J. Physiol. Heart Circ. Physiol. pmid:24043256
Ballantyne CM et al. Icosapent ethyl for the treatment of hypertriglyceridemia. 2013 Expert Opin Pharmacother pmid:23701295