4-hydroxy-butyric acid

4-hydroxy-butyric acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 8613 references associated with 4-hydroxy-butyric acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 4-hydroxy-butyric acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-hydroxy-butyric acid

MeSH term MeSH ID Detail
Abdominal Neoplasms D000008 1 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Abortion, Threatened D000033 2 associated lipids
Alcohol Withdrawal Delirium D000430 1 associated lipids
Alcoholism D000437 27 associated lipids
Amnesia D000647 12 associated lipids
Amnesia, Retrograde D000648 2 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Angina Pectoris D000787 27 associated lipids
Angina, Unstable D000789 14 associated lipids
Per page 10 20 50 100 | Total 113

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 4-hydroxy-butyric acid

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Per page 10 20 50 100 | Total 3045
Authors Title Published Journal PubMed Link
El-Habr EA et al. A driver role for GABA metabolism in controlling stem and proliferative cell state through GHB production in glioma. 2017 Acta Neuropathol. pmid:28032215
Busardò FP et al. Assessment of the stability of exogenous gamma hydroxybutyric acid (GHB) in stored blood and urine specimens. 2015 Eur Rev Med Pharmacol Sci pmid:26592846
Kim M et al. Two pathways for glutamate biosynthesis in the syntrophic bacterium Syntrophus aciditrophicus. 2015 Appl. Environ. Microbiol. pmid:26431966
Dave RA and Morris ME Semi-mechanistic kidney model incorporating physiologically-relevant fluid reabsorption and transporter-mediated renal reabsorption: pharmacokinetics of γ-hydroxybutyric acid and L-lactate in rats. 2015 J Pharmacokinet Pharmacodyn pmid:26341876
Bosch OG et al. Gamma-hydroxybutyrate enhances mood and prosocial behavior without affecting plasma oxytocin and testosterone. 2015 Psychoneuroendocrinology pmid:26209926
Kawase T et al. Novel fluorinated gemini surfactants with γ-butyrolactone segments. 2015 J Oleo Sci pmid:25748377
Otte J et al. Malonic semialdehyde reductase from the archaeon Nitrosopumilus maritimus is involved in the autotrophic 3-hydroxypropionate/4-hydroxybutyrate cycle. 2015 Appl. Environ. Microbiol. pmid:25548047
Luca G et al. Central and peripheral metabolic changes induced by gamma-hydroxybutyrate. 2015 Sleep pmid:25515097
Claussen MC et al. Catatonic stupor secondary to gamma-hydroxy-butyric acid (GHB)-dependence and -withdrawal syndrome. 2014 Psychiatr Danub pmid:25377371
Gould T et al. GABA(B) receptor-mediated activation of astrocytes by gamma-hydroxybutyric acid. 2014 Philos. Trans. R. Soc. Lond., B, Biol. Sci. pmid:25225100
Vijay N and Morris ME Effect of 3,4-methylenedioxymethamphetamine on the toxicokinetics and sedative effects of the drug of abuse, γ-hydroxybutyric acid. 2014 J Pharm Sci pmid:25174723
Cheung J et al. γ-Hydroxybutyric acid-induced electrographic seizures. 2014 J Clin Sleep Med pmid:25024661
Wendt G et al. Gamma-hydroxybutyrate, acting through an anti-apoptotic mechanism, protects native and amyloid-precursor-protein-transfected neuroblastoma cells against oxidative stress-induced death. 2014 Neuroscience pmid:24456637
Zhai D et al. Development of a fluorescent sensor for illicit date rape drug GHB. 2014 Chem. Commun. (Camb.) pmid:24492471
Krishnamurthy VB et al. An interesting case of late age at onset of narcolepsy with cataplexy. 2014 J Clin Sleep Med pmid:24533004
Korf DJ et al. Risk factors of γ-hydroxybutyrate overdosing. 2014 Eur Addict Res pmid:24080792
Stomberg MW et al. Symptoms and signs in interpreting gamma-hydroxybutyrate (GHB) intoxication - an explorative study. 2014 Scand J Trauma Resusc Emerg Med pmid:24758357
Black SW et al. GABAB agonism promotes sleep and reduces cataplexy in murine narcolepsy. 2014 J. Neurosci. pmid:24806675
Yiu CY et al. Inhibition of Epstein-Barr virus lytic cycle by an ethyl acetate subfraction separated from Polygonum cuspidatum root and its major component, emodin. 2014 Molecules pmid:24448066
Eghorn LF et al. Positive allosteric modulation of the GHB high-affinity binding site by the GABAA receptor modulator monastrol and the flavonoid catechin. 2014 Eur. J. Pharmacol. pmid:24973695