4-hydroxy-butyric acid

4-hydroxy-butyric acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 8613 references associated with 4-hydroxy-butyric acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.

Here are additional resources we collected from PubChem and MeSH for 4-hydroxy-butyric acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-hydroxy-butyric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Lung Neoplasms D008175 171 associated lipids
Inflammation D007249 119 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis D001168 41 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Coronary Disease D003327 70 associated lipids
Substance Withdrawal Syndrome D013375 9 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Muscular Dystrophies D009136 10 associated lipids
Femoral Fractures D005264 7 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Intellectual Disability D008607 13 associated lipids
Glioma D005910 112 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Myocardial Infarction D009203 21 associated lipids
Peritonitis D010538 38 associated lipids
Cardiac Complexes, Premature D005117 6 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Glaucoma D005901 5 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Ataxia D001259 20 associated lipids
Alcoholism D000437 27 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Starvation D013217 47 associated lipids
Brain Ischemia D002545 89 associated lipids
Epilepsy D004827 35 associated lipids
Seizures D012640 87 associated lipids
Peptic Ulcer D010437 19 associated lipids
Hypertension D006973 115 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Cerebral Infarction D002544 6 associated lipids
Fever D005334 35 associated lipids
Catalepsy D002375 30 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Radiation Injuries, Experimental D011833 11 associated lipids
Shock, Traumatic D012774 4 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Angina Pectoris D000787 27 associated lipids
Angina, Unstable D000789 14 associated lipids
Tremor D014202 15 associated lipids
Parkinson Disease D010300 53 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Psychomotor Disorders D011596 3 associated lipids
Poisoning D011041 9 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Muscular Dystrophy, Animal D009137 5 associated lipids
Cystadenocarcinoma D003536 3 associated lipids
Meningitis, Meningococcal D008585 2 associated lipids
Cataplexy D002385 2 associated lipids
Narcolepsy D009290 1 associated lipids
Dysgerminoma D004407 1 associated lipids
Language Development Disorders D007805 4 associated lipids
Cardiomyopathy, Alcoholic D002310 1 associated lipids
Uterine Inertia D014593 3 associated lipids
Abortion, Threatened D000033 2 associated lipids
Leukoencephalopathy, Progressive Multifocal D007968 1 associated lipids
Distemper D004216 1 associated lipids
Pseudotumor Cerebri D011559 2 associated lipids
Hallucinations D006212 4 associated lipids
Heat Exhaustion D006359 1 associated lipids
Myoclonus D009207 3 associated lipids
Spinal Cord Diseases D013118 4 associated lipids
Abdominal Neoplasms D000008 1 associated lipids
Sertoli-Leydig Cell Tumor D018310 1 associated lipids
Sleep Wake Disorders D012893 7 associated lipids
Burkholderia Infections D019121 7 associated lipids
Granulosa Cell Tumor D006106 1 associated lipids
Epilepsy, Absence D004832 5 associated lipids
Rheumatic Heart Disease D012214 1 associated lipids
Decerebrate State D003655 7 associated lipids
Pericarditis D010493 6 associated lipids
Spermatic Cord Torsion D013086 1 associated lipids
Alcohol Withdrawal Delirium D000430 1 associated lipids
Psychoses, Alcoholic D011604 2 associated lipids
Heart Septal Defects, Atrial D006344 1 associated lipids
Sleep Apnea Syndromes D012891 3 associated lipids
Disorders of Excessive Somnolence D006970 1 associated lipids
Amnesia D000647 12 associated lipids
Amnesia, Retrograde D000648 2 associated lipids
Fluoride Poisoning D005458 1 associated lipids
Drug Overdose D062787 2 associated lipids
Language Disorders D007806 1 associated lipids
Cocaine-Related Disorders D019970 3 associated lipids
Sleep Disorders, Circadian Rhythm D020178 3 associated lipids
Akathisia, Drug-Induced D017109 2 associated lipids
Autonomic Nervous System Diseases D001342 4 associated lipids
Heroin Dependence D006556 1 associated lipids
Alcohol-Related Disorders D019973 3 associated lipids
Consciousness Disorders D003244 2 associated lipids
Epilepsies, Myoclonic D004831 2 associated lipids
Alcohol Withdrawal Seizures D020270 1 associated lipids
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PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 4-hydroxy-butyric acid

Download all related citations
Per page 10 20 50 100 | Total 3045
Authors Title Published Journal PubMed Link
El-Habr EA et al. A driver role for GABA metabolism in controlling stem and proliferative cell state through GHB production in glioma. 2017 Acta Neuropathol. pmid:28032215
Busardò FP et al. Assessment of the stability of exogenous gamma hydroxybutyric acid (GHB) in stored blood and urine specimens. 2015 Eur Rev Med Pharmacol Sci pmid:26592846
Kim M et al. Two pathways for glutamate biosynthesis in the syntrophic bacterium Syntrophus aciditrophicus. 2015 Appl. Environ. Microbiol. pmid:26431966
Dave RA and Morris ME Semi-mechanistic kidney model incorporating physiologically-relevant fluid reabsorption and transporter-mediated renal reabsorption: pharmacokinetics of γ-hydroxybutyric acid and L-lactate in rats. 2015 J Pharmacokinet Pharmacodyn pmid:26341876
Bosch OG et al. Gamma-hydroxybutyrate enhances mood and prosocial behavior without affecting plasma oxytocin and testosterone. 2015 Psychoneuroendocrinology pmid:26209926
Kawase T et al. Novel fluorinated gemini surfactants with γ-butyrolactone segments. 2015 J Oleo Sci pmid:25748377
Otte J et al. Malonic semialdehyde reductase from the archaeon Nitrosopumilus maritimus is involved in the autotrophic 3-hydroxypropionate/4-hydroxybutyrate cycle. 2015 Appl. Environ. Microbiol. pmid:25548047
Luca G et al. Central and peripheral metabolic changes induced by gamma-hydroxybutyrate. 2015 Sleep pmid:25515097
Wendt G et al. Gamma-hydroxybutyrate, acting through an anti-apoptotic mechanism, protects native and amyloid-precursor-protein-transfected neuroblastoma cells against oxidative stress-induced death. 2014 Neuroscience pmid:24456637
Eghorn LF et al. Positive allosteric modulation of the GHB high-affinity binding site by the GABAA receptor modulator monastrol and the flavonoid catechin. 2014 Eur. J. Pharmacol. pmid:24973695