4-hydroxy-butyric acid

4-hydroxy-butyric acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 8613 references associated with 4-hydroxy-butyric acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 4-hydroxy-butyric acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-hydroxy-butyric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Lung Neoplasms D008175 171 associated lipids
Inflammation D007249 119 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis D001168 41 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Coronary Disease D003327 70 associated lipids
Substance Withdrawal Syndrome D013375 9 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Muscular Dystrophies D009136 10 associated lipids
Femoral Fractures D005264 7 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Intellectual Disability D008607 13 associated lipids
Glioma D005910 112 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Myocardial Infarction D009203 21 associated lipids
Peritonitis D010538 38 associated lipids
Cardiac Complexes, Premature D005117 6 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Glaucoma D005901 5 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Ataxia D001259 20 associated lipids
Alcoholism D000437 27 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Starvation D013217 47 associated lipids
Brain Ischemia D002545 89 associated lipids
Epilepsy D004827 35 associated lipids
Seizures D012640 87 associated lipids
Peptic Ulcer D010437 19 associated lipids
Hypertension D006973 115 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Cerebral Infarction D002544 6 associated lipids
Fever D005334 35 associated lipids
Catalepsy D002375 30 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Radiation Injuries, Experimental D011833 11 associated lipids
Shock, Traumatic D012774 4 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Angina Pectoris D000787 27 associated lipids
Angina, Unstable D000789 14 associated lipids
Tremor D014202 15 associated lipids
Parkinson Disease D010300 53 associated lipids
Per page 10 20 50 100 | Total 113

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 4-hydroxy-butyric acid

Download all related citations
Per page 10 20 50 100 | Total 3045
Authors Title Published Journal PubMed Link
Eghorn LF et al. Positive allosteric modulation of the GHB high-affinity binding site by the GABAA receptor modulator monastrol and the flavonoid catechin. 2014 Eur. J. Pharmacol. pmid:24973695
Johnson MW and Griffiths RR Comparative abuse liability of GHB and ethanol in humans. 2013 Exp Clin Psychopharmacol pmid:23421353
Petersen IN et al. Identification of a new metabolite of GHB: gamma-hydroxybutyric acid glucuronide. 2013 J Anal Toxicol pmid:23612681
Ingels AS et al. Determination of gamma-hydroxybutyric acid in biofluids using a one-step procedure with "in-vial" derivatization and headspace-trap gas chromatography-mass spectrometry. 2013 J Chromatogr A pmid:23664352
Rosi L et al. Determination of GHB and its precursors (GBL and 1,4-BD) in dietary supplements through the synthesis of their isotopologues and analysis by GC-MS method. 2013 J Pharm Biomed Anal pmid:23245230
Hawkins AS et al. Role of 4-hydroxybutyrate-CoA synthetase in the CO2 fixation cycle in thermoacidophilic archaea. 2013 J. Biol. Chem. pmid:23258541
Munshi T et al. Monitoring of the interconversion of gamma-butyrolactone (GBL) to gamma hydroxybutyric acid (GHB) by Raman spectroscopy. 2013 Drug Test Anal pmid:23225646
Amer B et al. Novel GHB-derived natural products from European mistletoe (Viscum album). 2013 Pharm Biol pmid:23734579
de Jong CA et al. Treatment of GHB withdrawal syndrome: Catch 22 or challenge for addiction medicine? 2013 Addiction pmid:23718746
Choi S et al. Production of 4-hydroxybutyric acid by metabolically engineered Mannheimia succiniciproducens and its conversion to γ-butyrolactone by acid treatment. 2013 Metab. Eng. pmid:24055777