4-hydroxy-butyric acid

4-hydroxy-butyric acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 8613 references associated with 4-hydroxy-butyric acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 4-hydroxy-butyric acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-hydroxy-butyric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Lung Neoplasms D008175 171 associated lipids
Inflammation D007249 119 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis D001168 41 associated lipids
Hypotension D007022 41 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Coronary Disease D003327 70 associated lipids
Substance Withdrawal Syndrome D013375 9 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Muscular Dystrophies D009136 10 associated lipids
Femoral Fractures D005264 7 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Intellectual Disability D008607 13 associated lipids
Glioma D005910 112 associated lipids
Metabolism, Inborn Errors D008661 46 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Myocardial Infarction D009203 21 associated lipids
Peritonitis D010538 38 associated lipids
Cardiac Complexes, Premature D005117 6 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Glaucoma D005901 5 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Ataxia D001259 20 associated lipids
Alcoholism D000437 27 associated lipids
Pseudomonas Infections D011552 25 associated lipids
Starvation D013217 47 associated lipids
Brain Ischemia D002545 89 associated lipids
Epilepsy D004827 35 associated lipids
Seizures D012640 87 associated lipids
Peptic Ulcer D010437 19 associated lipids
Hypertension D006973 115 associated lipids
Cerebrovascular Disorders D002561 25 associated lipids
Cerebral Infarction D002544 6 associated lipids
Fever D005334 35 associated lipids
Catalepsy D002375 30 associated lipids
Infant, Newborn, Diseases D007232 9 associated lipids
Radiation Injuries, Experimental D011833 11 associated lipids
Shock, Traumatic D012774 4 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Angina Pectoris D000787 27 associated lipids
Angina, Unstable D000789 14 associated lipids
Tremor D014202 15 associated lipids
Parkinson Disease D010300 53 associated lipids
Per page 10 20 50 100 | Total 113

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 4-hydroxy-butyric acid

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Per page 10 20 50 100 | Total 3045
Authors Title Published Journal PubMed Link
Wang HH et al. Biosynthesis of polyhydroxyalkanoate homopolymers by Pseudomonas putida. 2011 Appl. Microbiol. Biotechnol. pmid:21046374
Holder JW et al. Comparative and functional genomics of Rhodococcus opacus PD630 for biofuels development. 2011 PLoS Genet. pmid:21931557
van Wijk JP et al. Differential effects of rosiglitazone and metformin on postprandial lipemia in patients with HIV-lipodystrophy. 2011 Arterioscler. Thromb. Vasc. Biol. pmid:20947819
Fisher DG et al. Methamphetamine and Viagra use: relationship to sexual risk behaviors. 2011 Arch Sex Behav pmid:19330436
Davisson MT et al. A spontaneous mutation in contactin 1 in the mouse. 2011 PLoS ONE pmid:22242131
Merzouki S et al. 1-[3-(4-Nitro-phen-yl)propano-yl]urea acetic acid monosolvate. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:22219927
Felisbino MB et al. Chromatin remodeling, cell proliferation and cell death in valproic acid-treated HeLa cells. 2011 PLoS ONE pmid:22206001
Molnár T et al. Activation of astroglial calcium signaling by endogenous metabolites succinate and gamma-hydroxybutyrate in the nucleus accumbens. 2011 Front Neuroenergetics pmid:22180742
Hartley S et al. Sodium oxybate and sleep apnea: a clinical case. 2011 J Clin Sleep Med pmid:22171208
Schmidt A et al. Transcriptome analysis of the Arabidopsis megaspore mother cell uncovers the importance of RNA helicases for plant germline development. 2011 PLoS Biol. pmid:21949639
Akintomide GS and Rickards H Narcolepsy: a review. 2011 Neuropsychiatr Dis Treat pmid:21931493
Won SG and Lau AK Effects of key operational parameters on biohydrogen production via anaerobic fermentation in a sequencing batch reactor. 2011 Bioresour. Technol. pmid:21530239
Deng XL et al. [Succinic semialdehyde dehydrogenase deficiency]. 2011 Zhongguo Dang Dai Er Ke Za Zhi pmid:21924025
Feldman NT Sodium oxybate post-marketing surveillance. 2011 J Clin Sleep Med pmid:21897785
Wang YG et al. Sodium oxybate: updates and correction to previously published safety data. 2011 J Clin Sleep Med pmid:21897784
Crunelli V et al. Transition to absence seizures and the role of GABA(A) receptors. 2011 Epilepsy Res. pmid:21889315
Rice MW et al. Neurochemical characterization of the tree shrew dorsal striatum. 2011 Front Neuroanat pmid:21887131
Monteiro JC et al. More resistant tendons obtained from the association of Heteropterys aphrodisiaca and endurance training. 2011 BMC Complement Altern Med pmid:21711561
Poling JS et al. Pharmacologic correction of dominant-negative GH1 deficiency causing mutations. 2011 Clin Transl Sci pmid:21707947
O'Byrne P and Holmes D Drug use as boundary play: a qualitative exploration of gay circuit parties. 2011 Subst Use Misuse pmid:21692603
Kasischke K Lactate fuels the neonatal brain. 2011 Front Neuroenergetics pmid:21687795
Bubar MJ et al. 5-HT(2C) receptors localize to dopamine and GABA neurons in the rat mesoaccumbens pathway. 2011 PLoS ONE pmid:21687728
Marini F et al. MicroRNA Role in Thyroid Cancer Development. 2011 J Thyroid Res pmid:21687652
Thakur A et al. Experimental re-evaluation of flunarizine as add-on antiepileptic therapy. 2011 J Pharm Bioallied Sci pmid:21687355
Wallace DM et al. Sodium oxybate-induced sleep driving and sleep-related eating disorder. 2011 J Clin Sleep Med pmid:21677903
Fazakas C et al. Transmigration of melanoma cells through the blood-brain barrier: role of endothelial tight junctions and melanoma-released serine proteases. 2011 PLoS ONE pmid:21674054
Pearl PL et al. Epilepsy in succinic semialdehyde dehydrogenase deficiency, a disorder of GABA metabolism. 2011 Brain Dev. pmid:21664777
Grillo R et al. Controlled release system for ametryn using polymer microspheres: preparation, characterization and release kinetics in water. 2011 J. Hazard. Mater. pmid:21215514
Pecenková T et al. The role for the exocyst complex subunits Exo70B2 and Exo70H1 in the plant-pathogen interaction. 2011 J. Exp. Bot. pmid:21199889
Manore M et al. BJSM reviews: A-Z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance--Part 16. 2011 Br J Sports Med pmid:21169238
Schubert I et al. No evidence for "break-induced replication" in a higher plant - but break-induced conversion may occur. 2011 Front Plant Sci pmid:22639575
Ahmed K Biological roles and therapeutic potential of hydroxy-carboxylic Acid receptors. 2011 Front Endocrinol (Lausanne) pmid:22654812
Cooke SL et al. Intra-tumour genetic heterogeneity and poor chemoradiotherapy response in cervical cancer. 2011 Br. J. Cancer pmid:21063398
Li X et al. Reverse-genetic analysis of the two biotin-containing subunit genes of the heteromeric acetyl-coenzyme A carboxylase in Arabidopsis indicates a unidirectional functional redundancy. 2011 Plant Physiol. pmid:21030508
Paul S et al. Anticancer Potentials of Root Extract of Polygala senega and Its PLGA Nanoparticles-Encapsulated Form. 2011 Evid Based Complement Alternat Med pmid:20953431
Hasan L et al. An enzymatic method to determine γ-hydroxybutyric acid in serum and urine. 2011 Ther Drug Monit pmid:22105594
Spitzer AR and Broadman M Treatment of the narcoleptiform sleep disorder in chronic fatigue syndrome and fibromyalgia with sodium oxybate. 2010 Jan-Feb Pain Pract pmid:20629967
Singh H et al. Antidepressant/anxiolytic and anti-nociceptive effects of novel 2-substituted 1,4-benzodiazepine-2-ones. 2010 Apr-Jun Sci Pharm pmid:21179341
Robledo G et al. Genome re-assignment of Arachis trinitensis (Sect. Arachis, Leguminosae) and its implications for the genetic origin of cultivated peanut. 2010 Genet. Mol. Biol. pmid:21637581
Houel C et al. Patterns of sequence polymorphism in the fleshless berry locus in cultivated and wild Vitis vinifera accessions. 2010 BMC Plant Biol. pmid:21176183
O'Donoghue LE et al. Expression profiling in canine osteosarcoma: identification of biomarkers and pathways associated with outcome. 2010 BMC Cancer pmid:20860831
Walsh JK et al. Enhancing slow wave sleep with sodium oxybate reduces the behavioral and physiological impact of sleep loss. 2010 Sleep pmid:20857869
Schwartz JR et al. Armodafinil in the treatment of sleep/wake disorders. 2010 Neuropsychiatr Dis Treat pmid:20856606
Nole-Wilson S et al. Synergistic disruptions in seuss cyp85A2 double mutants reveal a role for brassinolide synthesis during gynoecium and ovule development. 2010 BMC Plant Biol. pmid:20836864
Devireddy LR et al. A mammalian siderophore synthesized by an enzyme with a bacterial homolog involved in enterobactin production. 2010 Cell pmid:20550936
Veerman SR et al. [Life threatening symptoms of withdrawal of gamma-hydroxybutyrate]. 2010 Tijdschr Psychiatr pmid:20544599
Gruber VA and McCance-Katz EF Methadone, buprenorphine, and street drug interactions with antiretroviral medications. 2010 Curr HIV/AIDS Rep pmid:20532839
Minea RO et al. Vicrostatin - an anti-invasive multi-integrin targeting chimeric disintegrin with tumor anti-angiogenic and pro-apoptotic activities. 2010 PLoS ONE pmid:20532165
Glattard E et al. Endogenous morphine levels are increased in sepsis: a partial implication of neutrophils. 2010 PLoS ONE pmid:20098709
Chai TT et al. Photosynthetic performance and fertility are repressed in GmAOX2b antisense soybean. 2010 Plant Physiol. pmid:20097793