| MeSH term | MeSH ID | Detail |
|---|---|---|
| Distemper | D004216 | 1 associated lipids |
| Alcohol Withdrawal Delirium | D000430 | 1 associated lipids |
| Narcolepsy | D009290 | 1 associated lipids |
| Aortic Stenosis, Supravalvular | D021921 | 1 associated lipids |
| Language Disorders | D007806 | 1 associated lipids |
| Granulosa Cell Tumor | D006106 | 1 associated lipids |
| Dysgerminoma | D004407 | 1 associated lipids |
| Alcohol Withdrawal Seizures | D020270 | 1 associated lipids |
| Heart Septal Defects, Atrial | D006344 | 1 associated lipids |
| Heat Exhaustion | D006359 | 1 associated lipids |
4-hydroxy-butyric acid
4-hydroxy-butyric acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 8613 references associated with 4-hydroxy-butyric acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for 4-hydroxy-butyric acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 4-hydroxy-butyric acid
PubChem Associated disorders and diseases
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with 4-hydroxy-butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Lora J et al. | The progamic phase of an early-divergent angiosperm, Annona cherimola (Annonaceae). | 2010 | Ann. Bot. | pmid:19939980 |
| Ramo DE et al. | Typology of club drug use among young adults recruited using time-space sampling. | 2010 | Drug Alcohol Depend | pmid:19939585 |
| Caputo F and Bernardi M | Medications acting on the GABA system in the treatment of alcoholic patients. | 2010 | Curr. Pharm. Des. | pmid:20482512 |
| Feldman NT | Clinical perspective: monitoring sodium oxybate-treated narcolepsy patients for the development of sleep-disordered breathing. | 2010 | Sleep Breath | pmid:19626356 |
| Watson J et al. | Gamma-hydroxybutyrate does not maintain self-administration but induces conditioned place preference when injected in the ventral tegmental area. | 2010 | Int. J. Neuropsychopharmacol. | pmid:19573264 |
| Kirmse K et al. | GABA depolarizes immature neocortical neurons in the presence of the ketone body ß-hydroxybutyrate. | 2010 | J. Neurosci. | pmid:21106838 |
| Marques A et al. | Karyotype differentiation in three species of Tripogandra Raf. (Commelinaceae) with different ploidy levels. | 2010 | Genet. Mol. Biol. | pmid:21637583 |
| Lahnsteiner F et al. | Composition and metabolism of carbohydrates and lipids in Sparus aurata semen and its relation to viability expressed as sperm motility when activated. | 2010 | Comp. Biochem. Physiol. B, Biochem. Mol. Biol. | pmid:20441800 |
| Merz H et al. | Interleukin-9 (IL-9) and NPM-ALK each generate mast cell hyperplasia as single 'hit' and cooperate in producing a mastocytosis-like disease in mice. | 2010 | Oncotarget | pmid:21297223 |
| La Cono V et al. | Genomic signatures of fifth autotrophic carbon assimilation pathway in bathypelagic Crenarchaeota. | 2010 | Microb Biotechnol | pmid:21255356 |
| Brown MT et al. | Drug-driven AMPA receptor redistribution mimicked by selective dopamine neuron stimulation. | 2010 | PLoS ONE | pmid:21209835 |
| Black J et al. | The nightly use of sodium oxybate is associated with a reduction in nocturnal sleep disruption: a double-blind, placebo-controlled study in patients with narcolepsy. | 2010 | J Clin Sleep Med | pmid:21206549 |
| Li S et al. | Efficacy of manual jet ventilation using Manujet III for bronchoscopic airway foreign body removal in children. | 2010 | Int. J. Pediatr. Otorhinolaryngol. | pmid:20951443 |
| Recla JM | New and emerging therapeutic agents for the treatment of fibromyalgia: an update. | 2010 | J Pain Res | pmid:21197313 |
| Sciotti MA et al. | Development and characterization of an enzymatic method for the rapid determination of gamma hydroxybutyric acid. | 2010 | Chimia (Aarau) | pmid:21197843 |
| Sun J et al. | Constraint-based modeling analysis of the metabolism of two Pelobacter species. | 2010 | BMC Syst Biol | pmid:21182788 |
| Moore TJ et al. | Prescription drugs associated with reports of violence towards others. | 2010 | PLoS ONE | pmid:21179515 |
| Aran A et al. | Clinical and therapeutic aspects of childhood narcolepsy-cataplexy: a retrospective study of 51 children. | 2010 | Sleep | pmid:21102987 |
| Victório SC et al. | Absence of IFNγ expression induces neuronal degeneration in the spinal cord of adult mice. | 2010 | J Neuroinflammation | pmid:21073708 |
| Li H et al. | Production of gamma-aminobutyric acid by Lactobacillus brevis NCL912 using fed-batch fermentation. | 2010 | Microb. Cell Fact. | pmid:21070676 |
| Pichini S et al. | Immunomodulating properties of gamma-hydroxybutyrate (GHB), flunitrazepam and ethanol in 'club drugs' users. | 2010 | Addict Biol | pmid:20456291 |
| Piantoni P et al. | Expression of metabolic, tissue remodeling, oxidative stress, and inflammatory pathways in mammary tissue during involution in lactating dairy cows. | 2010 | Bioinform Biol Insights | pmid:20981268 |
| Vienne J et al. | Differential effects of GABAB receptor subtypes, {gamma}-hydroxybutyric Acid, and Baclofen on EEG activity and sleep regulation. | 2010 | J. Neurosci. | pmid:20962240 |
| Berg IA et al. | Study of the distribution of autotrophic CO2 fixation cycles in Crenarchaeota. | 2010 | Microbiology (Reading, Engl.) | pmid:19850614 |
| Tchankouo-Nguetcheu S et al. | Differential protein modulation in midguts of Aedes aegypti infected with chikungunya and dengue 2 viruses. | 2010 | PLoS ONE | pmid:20957153 |
| Escalera GI et al. | [Succinic semialdehyde dehydrogenase deficiency: decrease in 4-OH-butyric acid levels with low doses of vigabatrin]. | 2010 | An Pediatr (Barc) | pmid:20018576 |
| Smejkalová H et al. | Methanol assimilation in Methylobacterium extorquens AM1: demonstration of all enzymes and their regulation. | 2010 | PLoS ONE | pmid:20957036 |
| Lam WK et al. | Monocarboxylate transporter-mediated transport of gamma-hydroxybutyric acid in human intestinal Caco-2 cells. | 2010 | Drug Metab. Dispos. | pmid:19952290 |
| van Zanten M et al. | Photoreceptors CRYTOCHROME2 and phytochrome B control chromatin compaction in Arabidopsis. | 2010 | Plant Physiol. | pmid:20935177 |
| Sircar R et al. | Effects of gamma-hydroxybutyric acid on spatial learning and memory in adolescent and adult female rats. | 2010 | Pharmacol. Biochem. Behav. | pmid:20460135 |
| Zvosec DL and Smith SW | Commenting on"a review of tolerability and abuse liability of gamma-hydroxybutyric acid for insomnia in patients with schizophrenia," by Kantrowitzet al. | 2010 | Clin Ther | pmid:20435247 |
| Felmlee MA et al. | Mechanistic toxicokinetic model for gamma-hydroxybutyric acid: inhibition of active renal reabsorption as a potential therapeutic strategy. | 2010 | AAPS J | pmid:20461486 |
| Baumes LA et al. | A colorimetric sensor array for the detection of the date-rape drug γ-hydroxybutyric acid (GHB): a supramolecular approach. | 2010 | Chemistry | pmid:20309968 |
| Schnackenberg BJ et al. | An acute dose of gamma-hydroxybutyric acid alters gene expression in multiple mouse brain regions. | 2010 | Neuroscience | pmid:20654702 |
| Koek W et al. | GABAB receptor-positive modulators: enhancement of GABAB receptor agonist effects in vivo. | 2010 | J. Pharmacol. Exp. Ther. | pmid:20628000 |
| Girish TS and Gopal B | Crystal structure of Staphylococcus aureus metallopeptidase (Sapep) reveals large domain motions between the manganese-bound and apo-states. | 2010 | J. Biol. Chem. | pmid:20610394 |
| Morsy MD et al. | A potential protective effect of alpha-tocopherol on vascular complication in spinal cord reperfusion injury in rats. | 2010 | J. Biomed. Sci. | pmid:20609232 |
| Exempt chemical mixtures containing gamma-butyrolactone. Final rule. | 2010 | Fed Regist | pmid:20608286 | |
| Hirose T et al. | Disruption of a gene for rice sucrose transporter, OsSUT1, impairs pollen function but pollen maturation is unaffected. | 2010 | J. Exp. Bot. | pmid:20603282 |
| Wuyts N et al. | High-contrast three-dimensional imaging of the Arabidopsis leaf enables the analysis of cell dimensions in the epidermis and mesophyll. | 2010 | Plant Methods | pmid:20598116 |
| Hou S et al. | Developmental stage-specific imprinting of IPL in domestic pigs (Sus scrofa). | 2010 | J. Biomed. Biotechnol. | pmid:20589073 |
| Bennett RM et al. | Identification of symptom and functional domains that fibromyalgia patients would like to see improved: a cluster analysis. | 2010 | BMC Musculoskelet Disord | pmid:20584327 |
| Yeats TH et al. | Mining the surface proteome of tomato (Solanum lycopersicum) fruit for proteins associated with cuticle biogenesis. | 2010 | J. Exp. Bot. | pmid:20571035 |
| Vardya I et al. | Plasticity of postsynaptic, but not presynaptic, GABAB receptors in SSADH deficient mice. | 2010 | Exp. Neurol. | pmid:20570675 |
| Frey N et al. | A kinesin with calponin-homology domain is involved in premitotic nuclear migration. | 2010 | J. Exp. Bot. | pmid:20566563 |
| Mancuso M et al. | Transposon Tn7 preferentially inserts into GAA*TTC triplet repeats under conditions conducive to Y*R*Y triplex formation. | 2010 | PLoS ONE | pmid:20559546 |
| Biscontin A et al. | New miRNA labeling method for bead-based quantification. | 2010 | BMC Mol. Biol. | pmid:20553585 |
| Covey PA et al. | A pollen-specific RALF from tomato that regulates pollen tube elongation. | 2010 | Plant Physiol. | pmid:20388667 |
| Koo BS et al. | Improvement of coenzyme Q(10) production by increasing the NADH/NAD(+) ratio in Agrobacterium tumefaciens. | 2010 | Biosci. Biotechnol. Biochem. | pmid:20378960 |
| Bortolato M et al. | GABAB receptor activation exacerbates spontaneous spike-and-wave discharges in DBA/2J mice. | 2010 | Seizure | pmid:20233662 |
| Felmlee MA et al. | Concentration-effect relationships for the drug of abuse gamma-hydroxybutyric acid. | 2010 | J. Pharmacol. Exp. Ther. | pmid:20215411 |
| Alano CC et al. | NAD+ depletion is necessary and sufficient for poly(ADP-ribose) polymerase-1-mediated neuronal death. | 2010 | J. Neurosci. | pmid:20181594 |
| Langendorf CG et al. | The X-ray crystal structure of Escherichia coli succinic semialdehyde dehydrogenase; structural insights into NADP+/enzyme interactions. | 2010 | PLoS ONE | pmid:20174634 |
| Moulton CJ et al. | A high protein moderate carbohydrate diet fed at discrete meals reduces early progression of N-methyl-N-nitrosourea-induced breast tumorigenesis in rats. | 2010 | Nutr Metab (Lond) | pmid:20148110 |
| Bugler B et al. | Unscheduled expression of CDC25B in S-phase leads to replicative stress and DNA damage. | 2010 | Mol. Cancer | pmid:20128929 |
| Hazak O et al. | A rho scaffold integrates the secretory system with feedback mechanisms in regulation of auxin distribution. | 2010 | PLoS Biol. | pmid:20098722 |
| Parsons JT et al. | Club drug use and dependence among young adults recruited through time-space sampling. | 2009 Mar-Apr | Public Health Rep | pmid:19320366 |
| Fieguth A et al. | [First report of lethal gamma-hydroxybutyrate (GHB) intoxication after consumption of gamma-butyrolactone (GBL) in Lower Saxony]. | 2009 Jan-Feb | Arch Kriminol | pmid:19323150 |
| Poza-Aldea JJ | [Integrated treatment of the symptoms of narcolepsy-cataplexy syndrome with sodium oxybate]. | 2009 Jan 1-15 | Rev Neurol | pmid:19145563 |
| Liu BF et al. | Hydrogen production by immobilized R. faecalis RLD-53 using soluble metabolites from ethanol fermentation bacteria E. harbinense B49. | 2009 | Bioresour. Technol. | pmid:19200719 |
| Constantinides P and Vincent P | Chronic gamma-hydroxybutyric-acid use followed by gamma-hydroxybutyric-acid withdrawal mimic schizophrenia: a case report. | 2009 | Cases J | pmid:19829990 |
| Tengs T et al. | Characterization of unknown genetic modifications using high throughput sequencing and computational subtraction. | 2009 | BMC Biotechnol. | pmid:19814792 |
| Meng PH et al. | Crosstalks between myo-inositol metabolism, programmed cell death and basal immunity in Arabidopsis. | 2009 | PLoS ONE | pmid:19812700 |
| Decker MJ et al. | Electroencephalographic correlates of Chronic Fatigue Syndrome. | 2009 | Behav Brain Funct | pmid:19807920 |
| Daviña JR et al. | Chromosome studies in Orchidaceae from Argentina. | 2009 | Genet. Mol. Biol. | pmid:21637459 |
| Carlson PE et al. | Transcriptional profiling of Bacillus anthracis Sterne (34F2) during iron starvation. | 2009 | PLoS ONE | pmid:19768119 |
| Allan WL et al. | Role of plant glyoxylate reductases during stress: a hypothesis. | 2009 | Biochem. J. | pmid:19740079 |
| Tessadori F et al. | Phytochrome B and histone deacetylase 6 control light-induced chromatin compaction in Arabidopsis thaliana. | 2009 | PLoS Genet. | pmid:19730687 |
| Lam le H et al. | Flow injection analysis of angiotensin I-converting enzyme inhibitory activity with enzymatic reactors. | 2009 | Talanta | pmid:19615521 |
| Zhang GF et al. | Catabolism of 4-hydroxyacids and 4-hydroxynonenal via 4-hydroxy-4-phosphoacyl-CoAs. | 2009 | J. Biol. Chem. | pmid:19759021 |
| Gu J et al. | A genome scan for positive selection in thoroughbred horses. | 2009 | PLoS ONE | pmid:19503617 |
| Huffman KM et al. | Relationships between circulating metabolic intermediates and insulin action in overweight to obese, inactive men and women. | 2009 | Diabetes Care | pmid:19502541 |
| Carter LP et al. | Illicit gamma-hydroxybutyrate (GHB) and pharmaceutical sodium oxybate (Xyrem): differences in characteristics and misuse. | 2009 | Drug Alcohol Depend | pmid:19493637 |
| Zeitzer JM et al. | Modafinil and γ-hydroxybutyrate have sleep state-specific pharmacological actions on hypocretin-1 physiology in a primate model of human sleep. | 2009 | Behav Pharmacol | pmid:19752724 |
| Buxton JA et al. | The context of illicit drug overdose deaths in British Columbia, 2006. | 2009 | Harm Reduct J | pmid:19480677 |
| Lake JA and Wade RN | Plant-pathogen interactions and elevated CO2: morphological changes in favour of pathogens. | 2009 | J. Exp. Bot. | pmid:19470658 |
| Simard F et al. | Ecological niche partitioning between Anopheles gambiae molecular forms in Cameroon: the ecological side of speciation. | 2009 | BMC Ecol. | pmid:19460146 |
| Grov C et al. | Polydrug use among club-going young adults recruited through time-space sampling. | 2009 | Subst Use Misuse | pmid:19444726 |
| Sirchia SM et al. | Misbehaviour of XIST RNA in breast cancer cells. | 2009 | PLoS ONE | pmid:19440381 |
| Xiao H et al. | Integration of tomato reproductive developmental landmarks and expression profiles, and the effect of SUN on fruit shape. | 2009 | BMC Plant Biol. | pmid:19422692 |
| Marcucci KT et al. | Identification of two distinct structural regions in a human porcine endogenous retrovirus receptor, HuPAR2, contributing to function for viral entry. | 2009 | Retrovirology | pmid:19144196 |
| Russell IJ et al. | Sodium oxybate relieves pain and improves function in fibromyalgia syndrome: a randomized, double-blind, placebo-controlled, multicenter clinical trial. | 2009 | Arthritis Rheum. | pmid:19116896 |
| Souza LG et al. | The karyotype of Nothoscordum arenarium Herter (Gilliesioideae, Alliaceae): A populational and cytomolecular analysis. | 2009 | Genet. Mol. Biol. | pmid:21637654 |
| Paterson NE et al. | Pharmacological characterization of harmaline-induced tremor activity in mice. | 2009 | Eur. J. Pharmacol. | pmid:19497322 |
| Filová E et al. | Tissue-engineered heart valves. | 2009 | Physiol Res | pmid:20131932 |
| Hall AP | Narcolepsy: a brain structural abnormality and more of interest to the anaesthetist! | 2009 | Anaesthesia | pmid:19087017 |
| Shi R et al. | Recent advances in synthetic bioelastomers. | 2009 | Int J Mol Sci | pmid:20057942 |
| Sgaravatti AM et al. | Effects of 1,4-butanediol administration on oxidative stress in rat brain: study of the neurotoxicity of gamma-hydroxybutyric acid in vivo. | 2009 | Metab Brain Dis | pmid:19296210 |
| Kockelkorn D and Fuchs G | Malonic semialdehyde reductase, succinic semialdehyde reductase, and succinyl-coenzyme A reductase from Metallosphaera sedula: enzymes of the autotrophic 3-hydroxypropionate/4-hydroxybutyrate cycle in Sulfolobales. | 2009 | J. Bacteriol. | pmid:19684143 |
| Karila L et al. | [Gamma-hydroxybutyric acid (GHB): more than a date rape drug, a potentially addictive drug]. | 2009 | Presse Med | pmid:19762202 |
| Kantrowitz JT et al. | A review of tolerability and abuse liability of gamma-hydroxybutyric acid for insomnia in patients with schizophrenia. | 2009 | Clin Ther | pmid:19698899 |
| Liu C et al. | Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81. | 2009 | J. Biol. Chem. | pmid:19047060 |
| Benarroch EE | Gamma-hydroxybutyric acid and its relevance in neurology. | 2009 | Neurology | pmid:19153376 |
| Elsing C et al. | Gamma-hydroxybutyric acid versus clomethiazole for the treatment of alcohol withdrawal syndrome in a medical intensive care unit: an open, single-center randomized study. | 2009 | Am J Drug Alcohol Abuse | pmid:19462303 |
| Di Rosa G et al. | Visual evoked potentials in succinate semialdehyde dehydrogenase (SSADH) deficiency. | 2009 | J. Inherit. Metab. Dis. | pmid:19484191 |
| Marks DM et al. | Serotonin-norepinephrine reuptake inhibitors for pain control: premise and promise. | 2009 | Curr Neuropharmacol | pmid:20514212 |
| Takanashi M et al. | Characterization of a novel 3-hydroxybutyrate dehydrogenase from Ralstonia pickettii T1. | 2009 | Antonie Van Leeuwenhoek | pmid:19219638 |
| Wright AD et al. | Detailed NMR, including 1,1-ADEQUATE, and anticancer studies of compounds from the echinoderm Colobometra perspinosa. | 2009 | Mar Drugs | pmid:20098598 |
| Nakashima K et al. | Closed complex of the D-3-hydroxybutyrate dehydrogenase induced by an enantiomeric competitive inhibitor. | 2009 | J. Biochem. | pmid:19122202 |
| Congyang L et al. | Plasma cells increased markedly in lymph node in hemophagocytic syndrome: a case report. | 2009 | Cases J | pmid:20062733 |