4-hydroxy-butyric acid

4-hydroxy-butyric acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 8613 references associated with 4-hydroxy-butyric acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

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Here are additional resources we collected from PubChem and MeSH for 4-hydroxy-butyric acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-hydroxy-butyric acid

MeSH term MeSH ID Detail
Abdominal Neoplasms D000008 1 associated lipids
Abnormalities, Multiple D000015 13 associated lipids
Abortion, Threatened D000033 2 associated lipids
Alcohol Withdrawal Delirium D000430 1 associated lipids
Alcoholism D000437 27 associated lipids
Amnesia D000647 12 associated lipids
Amnesia, Retrograde D000648 2 associated lipids
Anemia, Sickle Cell D000755 34 associated lipids
Angina Pectoris D000787 27 associated lipids
Angina, Unstable D000789 14 associated lipids
Per page 10 20 50 100 | Total 113

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 4-hydroxy-butyric acid

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Authors Title Published Journal PubMed Link
Elian AA and Hackett J Anion exchange SPE and liquid chromatography-tandem mass spectrometry in GHB analysis. 2011 J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. pmid:22055831
Wang HH et al. Biosynthesis of polyhydroxyalkanoate homopolymers by Pseudomonas putida. 2011 Appl. Microbiol. Biotechnol. pmid:21046374
Lane T et al. High HIV prevalence among men who have sex with men in Soweto, South Africa: results from the Soweto Men's Study. 2011 AIDS Behav pmid:19662523
Swick TJ Sodium oxybate: a potential new pharmacological option for the treatment of fibromyalgia syndrome. 2011 Ther Adv Musculoskelet Dis pmid:22870476
Nesic J et al. A role for glutamate in subjective response to smoking and its action on inhibitory control. 2011 Psychopharmacology (Berl.) pmid:21301814
Sharakhova MV et al. Imaginal discs--a new source of chromosomes for genome mapping of the yellow fever mosquito Aedes aegypti. 2011 PLoS Negl Trop Dis pmid:21991400
Kamberov YG et al. Microarray profiling reveals the integrated stress response is activated by halofuginone in mammary epithelial cells. 2011 BMC Res Notes pmid:21974968
Molnár T et al. Calcium signals in the nucleus accumbens: activation of astrocytes by ATP and succinate. 2011 BMC Neurosci pmid:21967230
Won SG and Lau AK Effects of key operational parameters on biohydrogen production via anaerobic fermentation in a sequencing batch reactor. 2011 Bioresour. Technol. pmid:21530239
Payne CM et al. Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis. 2011 Clin Exp Gastroenterol pmid:21753893
Poli A et al. Synthesis, production, and biotechnological applications of exopolysaccharides and polyhydroxyalkanoates by archaea. 2011 Archaea pmid:22007151
Yelamanchili SV et al. Upregulation of cathepsin D in the caudate nucleus of primates with experimental parkinsonism. 2011 Mol Neurodegener pmid:21777416
Li W and Liu M Distribution of 5-hydroxymethylcytosine in different human tissues. 2011 J Nucleic Acids pmid:21772996
Smith HS et al. Pharmacotherapy for fibromyalgia. 2011 Front Pharmacol pmid:21772818
Alves LI et al. Chromosome characterization and variability in some Iridaceae from Northeastern Brazil. 2011 Genet. Mol. Biol. pmid:21734827
de França Rocha M et al. Comparative cytogenetic analysis of two grasshopper species of the tribe Abracrini (Ommatolampinae, Acrididae). 2011 Genet. Mol. Biol. pmid:21734819
Chakraborty K et al. Club drugs: review of the 'rave' with a note of concern for the Indian scenario. 2011 Indian J. Med. Res. pmid:21727657
Torres R et al. Biochemical, structural and molecular dynamics analyses of the potential virulence factor RipA from Yersinia pestis. 2011 PLoS ONE pmid:21966419
Wei YH et al. Biodegradable and biocompatible biomaterial, polyhydroxybutyrate, produced by an indigenous Vibrio sp. BM-1 isolated from marine environment. 2011 Mar Drugs pmid:21731553
Soo JK et al. Malignancy without immortality? Cellular immortalization as a possible late event in melanoma progression. 2011 Pigment Cell Melanoma Res pmid:21418545
Urquhart W et al. The cyclic nucleotide-gated channels AtCNGC11 and 12 are involved in multiple Ca²⁺-dependent physiological responses and act in a synergistic manner. 2011 J. Exp. Bot. pmid:21414958
Poryazova R et al. Sodium oxybate in narcolepsy with cataplexy: Zurich sleep center experience. 2011 Eur. Neurol. pmid:21389728
Pujalté I et al. Cytotoxicity and oxidative stress induced by different metallic nanoparticles on human kidney cells. 2011 Part Fibre Toxicol pmid:21371295
Andresen H et al. An overview of gamma-hydroxybutyric acid: pharmacodynamics, pharmacokinetics, toxic effects, addiction, analytical methods, and interpretation of results. 2011 Drug Test Anal pmid:21381220
Sanna E et al. Voluntary Ethanol Consumption Induced by Social Isolation Reverses the Increase of α(4)/δ GABA(A) Receptor Gene Expression and Function in the Hippocampus of C57BL/6J Mice. 2011 Front Neurosci pmid:21347217
Felmlee MA et al. Use of a local sensitivity analysis to inform study design based on a mechanistic toxicokinetic model for γ-hydroxybutyric acid. 2011 AAPS J pmid:21387146
Marclay F et al. Source inference of exogenous gamma-hydroxybutyric acid (GHB) administered to humans by means of carbon isotopic ratio analysis: novel perspectives regarding forensic investigation and intelligence issues. 2011 Anal Bioanal Chem pmid:21455654
Ando Y et al. Two-step cleavage of hairpin RNA with 5' overhangs by human DICER. 2011 BMC Mol. Biol. pmid:21306637
Cagnin A et al. γ-Hydroxybutyric acid-induced psychosis and seizures. 2011 Epilepsy Behav pmid:21530412
Lenz D et al. Inhibition of 1,4-butanediol metabolism in human liver in vitro. 2011 Naunyn Schmiedebergs Arch. Pharmacol. pmid:21533996
Wamelink MM et al. 4-Hydroxybutyric aciduria associated with catheter usage: a diagnostic pitfall in the identification of SSADH deficiency. 2011 Mol. Genet. Metab. pmid:20965758
Kim KJ et al. Succinic semialdehyde dehydrogenase: biochemical-molecular-clinical disease mechanisms, redox regulation, and functional significance. 2011 Antioxid. Redox Signal. pmid:20973619
Maurer GD et al. Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy. 2011 BMC Cancer pmid:21791085
Donjacour CE et al. Sodium oxybate increases prolactin secretion in narcolepsy patients and healthy controls. 2011 Eur. J. Endocrinol. pmid:21148631
Juchimiuk-Kwasniewska J et al. FISH in analysis of gamma ray-induced micronuclei formation in barley. 2011 J. Appl. Genet. pmid:21136232
Goodwin AK et al. Intravenous self-administration of γ-hydroxybutyrate (GHB) in baboons. 2011 Drug Alcohol Depend pmid:21112162
Spitzer AR and Broadman M Treatment of the narcoleptiform sleep disorder in chronic fatigue syndrome and fibromyalgia with sodium oxybate. 2010 Jan-Feb Pain Pract pmid:20629967
Singh H et al. Antidepressant/anxiolytic and anti-nociceptive effects of novel 2-substituted 1,4-benzodiazepine-2-ones. 2010 Apr-Jun Sci Pharm pmid:21179341
Coune P et al. Calcium and cAMP signaling induced by gamma-hydroxybutyrate receptor(s) stimulation in NCB-20 neurons. 2010 Neuroscience pmid:20153403
Stout PA et al. Quantitative analysis of gamma-hydroxybutyrate at endogenous concentrations in hair using liquid chromatography tandem mass spectrometry. 2010 J. Forensic Sci. pmid:20141559
Merz H et al. Interleukin-9 (IL-9) and NPM-ALK each generate mast cell hyperplasia as single 'hit' and cooperate in producing a mastocytosis-like disease in mice. 2010 Oncotarget pmid:21297223
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Li S et al. Efficacy of manual jet ventilation using Manujet III for bronchoscopic airway foreign body removal in children. 2010 Int. J. Pediatr. Otorhinolaryngol. pmid:20951443
Victório SC et al. Absence of IFNγ expression induces neuronal degeneration in the spinal cord of adult mice. 2010 J Neuroinflammation pmid:21073708
Escalera GI et al. [Succinic semialdehyde dehydrogenase deficiency: decrease in 4-OH-butyric acid levels with low doses of vigabatrin]. 2010 An Pediatr (Barc) pmid:20018576
Lam WK et al. Monocarboxylate transporter-mediated transport of gamma-hydroxybutyric acid in human intestinal Caco-2 cells. 2010 Drug Metab. Dispos. pmid:19952290
Girish TS and Gopal B Crystal structure of Staphylococcus aureus metallopeptidase (Sapep) reveals large domain motions between the manganese-bound and apo-states. 2010 J. Biol. Chem. pmid:20610394
Morsy MD et al. A potential protective effect of alpha-tocopherol on vascular complication in spinal cord reperfusion injury in rats. 2010 J. Biomed. Sci. pmid:20609232
Exempt chemical mixtures containing gamma-butyrolactone. Final rule. 2010 Fed Regist pmid:20608286
Bortolato M et al. GABAB receptor activation exacerbates spontaneous spike-and-wave discharges in DBA/2J mice. 2010 Seizure pmid:20233662