| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Diabetic Ketoacidosis | D016883 | 16 associated lipids |
| Lung Neoplasms | D008175 | 171 associated lipids |
| Inflammation | D007249 | 119 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Edema | D004487 | 152 associated lipids |
| Arthritis | D001168 | 41 associated lipids |
4-hydroxy-butyric acid
4-hydroxy-butyric acid is a lipid of Fatty Acyls (FA) class.
Cross Reference
There are no associated biomedical information in the current reference collection.
Current reference collection contains 8613 references associated with 4-hydroxy-butyric acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.
Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.
Here are additional resources we collected from PubChem and MeSH for 4-hydroxy-butyric acid
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 4-hydroxy-butyric acid
PubChem Associated disorders and diseases
PubChem Biomolecular Interactions and Pathways
NCBI Entrez Crosslinks
All references with 4-hydroxy-butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| El-Habr EA et al. | A driver role for GABA metabolism in controlling stem and proliferative cell state through GHB production in glioma. | 2017 | Acta Neuropathol. | pmid:28032215 |
| Busardò FP et al. | Assessment of the stability of exogenous gamma hydroxybutyric acid (GHB) in stored blood and urine specimens. | 2015 | Eur Rev Med Pharmacol Sci | pmid:26592846 |
| Kim M et al. | Two pathways for glutamate biosynthesis in the syntrophic bacterium Syntrophus aciditrophicus. | 2015 | Appl. Environ. Microbiol. | pmid:26431966 |
| Dave RA and Morris ME | Semi-mechanistic kidney model incorporating physiologically-relevant fluid reabsorption and transporter-mediated renal reabsorption: pharmacokinetics of γ-hydroxybutyric acid and L-lactate in rats. | 2015 | J Pharmacokinet Pharmacodyn | pmid:26341876 |
| Bosch OG et al. | Gamma-hydroxybutyrate enhances mood and prosocial behavior without affecting plasma oxytocin and testosterone. | 2015 | Psychoneuroendocrinology | pmid:26209926 |
| Kawase T et al. | Novel fluorinated gemini surfactants with γ-butyrolactone segments. | 2015 | J Oleo Sci | pmid:25748377 |
| Otte J et al. | Malonic semialdehyde reductase from the archaeon Nitrosopumilus maritimus is involved in the autotrophic 3-hydroxypropionate/4-hydroxybutyrate cycle. | 2015 | Appl. Environ. Microbiol. | pmid:25548047 |
| Luca G et al. | Central and peripheral metabolic changes induced by gamma-hydroxybutyrate. | 2015 | Sleep | pmid:25515097 |
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| Gould T et al. | GABA(B) receptor-mediated activation of astrocytes by gamma-hydroxybutyric acid. | 2014 | Philos. Trans. R. Soc. Lond., B, Biol. Sci. | pmid:25225100 |
| Vijay N and Morris ME | Effect of 3,4-methylenedioxymethamphetamine on the toxicokinetics and sedative effects of the drug of abuse, γ-hydroxybutyric acid. | 2014 | J Pharm Sci | pmid:25174723 |
| Cheung J et al. | γ-Hydroxybutyric acid-induced electrographic seizures. | 2014 | J Clin Sleep Med | pmid:25024661 |
| Wendt G et al. | Gamma-hydroxybutyrate, acting through an anti-apoptotic mechanism, protects native and amyloid-precursor-protein-transfected neuroblastoma cells against oxidative stress-induced death. | 2014 | Neuroscience | pmid:24456637 |
| Zhai D et al. | Development of a fluorescent sensor for illicit date rape drug GHB. | 2014 | Chem. Commun. (Camb.) | pmid:24492471 |
| Kamal RM et al. | Decision rules for GHB (γ-hydroxybutyric acid) detoxification: a vignette study. | 2014 | Drug Alcohol Depend | pmid:24380737 |
| Krishnamurthy VB et al. | An interesting case of late age at onset of narcolepsy with cataplexy. | 2014 | J Clin Sleep Med | pmid:24533004 |
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| Yiu CY et al. | Inhibition of Epstein-Barr virus lytic cycle by an ethyl acetate subfraction separated from Polygonum cuspidatum root and its major component, emodin. | 2014 | Molecules | pmid:24448066 |
| Eghorn LF et al. | Positive allosteric modulation of the GHB high-affinity binding site by the GABAA receptor modulator monastrol and the flavonoid catechin. | 2014 | Eur. J. Pharmacol. | pmid:24973695 |
| Goodwin AK et al. | Self-administration of gamma-hydroxybutyric acid (GHB) precursors gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD) in baboons. | 2013 | Psychopharmacology (Berl.) | pmid:22945514 |
| Johnson MW and Griffiths RR | Comparative abuse liability of GHB and ethanol in humans. | 2013 | Exp Clin Psychopharmacol | pmid:23421353 |
| Petersen IN et al. | Identification of a new metabolite of GHB: gamma-hydroxybutyric acid glucuronide. | 2013 | J Anal Toxicol | pmid:23612681 |
| Ingels AS et al. | Determination of gamma-hydroxybutyric acid in biofluids using a one-step procedure with "in-vial" derivatization and headspace-trap gas chromatography-mass spectrometry. | 2013 | J Chromatogr A | pmid:23664352 |
| Rosi L et al. | Determination of GHB and its precursors (GBL and 1,4-BD) in dietary supplements through the synthesis of their isotopologues and analysis by GC-MS method. | 2013 | J Pharm Biomed Anal | pmid:23245230 |
| Hawkins AS et al. | Role of 4-hydroxybutyrate-CoA synthetase in the CO2 fixation cycle in thermoacidophilic archaea. | 2013 | J. Biol. Chem. | pmid:23258541 |
| Munshi T et al. | Monitoring of the interconversion of gamma-butyrolactone (GBL) to gamma hydroxybutyric acid (GHB) by Raman spectroscopy. | 2013 | Drug Test Anal | pmid:23225646 |
| Amer B et al. | Novel GHB-derived natural products from European mistletoe (Viscum album). | 2013 | Pharm Biol | pmid:23734579 |
| de Jong CA et al. | Treatment of GHB withdrawal syndrome: Catch 22 or challenge for addiction medicine? | 2013 | Addiction | pmid:23718746 |
| Choi S et al. | Production of 4-hydroxybutyric acid by metabolically engineered Mannheimia succiniciproducens and its conversion to γ-butyrolactone by acid treatment. | 2013 | Metab. Eng. | pmid:24055777 |
| Liu X et al. | The psychostimulant modafinil enhances gap junctional communication in cortical astrocytes. | 2013 | Neuropharmacology | pmid:23665355 |
| Forni S et al. | Quantitation of gamma-hydroxybutyric acid in dried blood spots: feasibility assessment for newborn screening of succinic semialdehyde dehydrogenase (SSADH) deficiency. | 2013 | Mol. Genet. Metab. | pmid:23742746 |
| Hermann-Krauss C et al. | Archaeal production of polyhydroxyalkanoate (PHA) co- and terpolyesters from biodiesel industry-derived by-products. | 2013 | Archaea | pmid:24453697 |
| Vogensen SB et al. | New synthesis and tritium labeling of a selective ligand for studying high-affinity γ-hydroxybutyrate (GHB) binding sites. | 2013 | J. Med. Chem. | pmid:24053696 |
| Spaeth M et al. | Long-term tolerability and maintenance of therapeutic response to sodium oxybate in an open-label extension study in patients with fibromyalgia. | 2013 | Arthritis Res. Ther. | pmid:24286114 |
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| Roiko SA et al. | Brain uptake of the drug of abuse γ-hydroxybutyric acid in rats. | 2012 | Drug Metab. Dispos. | pmid:22019629 |
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| Papackova Z et al. | Kupffer cells ameliorate hepatic insulin resistance induced by high-fat diet rich in monounsaturated fatty acids: the evidence for the involvement of alternatively activated macrophages. | 2012 | Nutr Metab (Lond) | pmid:22439764 |
| Winiarczyk K et al. | Characterization of callase (β-1,3-D-glucanase) activity during microsporogenesis in the sterile anthers of Allium sativum L. and the fertile anthers of A. atropurpureum. | 2012 | Sex. Plant Reprod. | pmid:22438078 |
| Buddhala C et al. | Calpain cleavage of brain glutamic acid decarboxylase 65 is pathological and impairs GABA neurotransmission. | 2012 | PLoS ONE | pmid:22427928 |
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| Becker S and Schweinhardt P | Dysfunctional neurotransmitter systems in fibromyalgia, their role in central stress circuitry and pharmacological actions on these systems. | 2012 | Pain Res Treat | pmid:22110944 |
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| Marinetti LJ et al. | Gamma butyrolactone (GBL) and gamma valerolactone (GVL): similarities and differences in their effects on the acoustic startle reflex and the conditioned enhancement of startle in the rat. | 2012 | Pharmacol. Biochem. Behav. | pmid:22349589 |
| Zörntlein SW et al. | In vitro production of GHB in blood and serum samples under various storage conditions. | 2012 | Forensic Sci. Int. | pmid:21880442 |