4-hydroxy-butyric acid

4-hydroxy-butyric acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 8613 references associated with 4-hydroxy-butyric acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 4-hydroxy-butyric acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-hydroxy-butyric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Lung Neoplasms D008175 171 associated lipids
Inflammation D007249 119 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis D001168 41 associated lipids
Per page 10 20 50 100 | Total 113

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 4-hydroxy-butyric acid

Download all related citations
Per page 10 20 50 100 | Total 3045
Authors Title Published Journal PubMed Link
pmid:
Dueñas Laita A [Gamma-hydroxybutyric acid or "liquid ecstasy": a poisoning to come?]. 1998 Med Clin (Barc) pmid:10026037
Ferrara SD et al. Effects of single dose of gamma-hydroxybutyric acid and lorazepam on psychomotor performance and subjective feelings in healthy volunteers. 1999 Eur. J. Clin. Pharmacol. pmid:10027654
Sethy VH et al. Effect of anesthetic doses of gamma-hydroxybutyrate on the acetylcholine content of rat brain. 1976 Naunyn Schmiedebergs Arch. Pharmacol. pmid:1004645
Addolorato G et al. A case of gamma-hydroxybutyric acid withdrawal syndrome during alcohol addiction treatment: utility of diazepam administration. 1999 Jan-Feb Clin Neuropharmacol pmid:10047936
Doherty JD et al. Identification of endogenous gamma-hydroxybutyrate in human and bovine brain and its regional distribution in human, guinea pig and rhesus monkey brain. 1978 J. Pharmacol. Exp. Ther. pmid:100596
Baldy-Moulinier M et al. [Prolonged traumatic and vascular coma: prognostic and therapeutic indications based on hemodynamic and metabolic studies]. 1976 Rev. Neurol. (Paris) pmid:1006013
Poldrugo F and Addolorato G The role of gamma-hydroxybutyric acid in the treatment of alcoholism: from animal to clinical studies. 1999 Jan-Feb Alcohol Alcohol. pmid:10075397
Masliah-Planchon R et al. [Study of 100 cesarean sections under general anesthesia with alfathesine. Comparison with 100 cesarean sections under general anesthesia with pentobarbital and with Na gamma hydroxybutyrate]. 1976 Sep-Oct Anesth Analg (Paris) pmid:1008286
Maruhn D et al. Normal limits of urinary excretion of eleven enzymes. 1976 Clin. Chem. pmid:10092
Matsuda M and Kawamata I Effect of succinic semialdehyde on seizure caused by vitamin B6 antagonists. 1976 J. Nutr. Sci. Vitaminol. pmid:1011043
Cott J et al. Suppression of ethanol-induced locomotor stimulation by GABA-like drugs. 1976 Naunyn Schmiedebergs Arch. Pharmacol. pmid:1012342
Iazvikov VV et al. [Quantitative histochemical study of fatty acid oxidation in the myocardium and skeletal muscles of rats under physical stress]. 1976 Sep-Oct Vopr. Med. Khim. pmid:1014473
Snead OC Gamma hydroxybutyrate in the monkey. III. Effect of intravenous anticonvulsant drugs. 1978 Neurology pmid:101897
Snead OC Gamma hydroxybutyrate in the monkey. IV. Dopaminergic mechanisms. 1978 Neurology pmid:101898
Rick JT et al. gamma-Hydroxybutyric acid, imidazoleacetic acid, cerebral metabolism and induced sleep. 1973 Isr. J. Med. Sci. pmid:10189872
Stefanini GF et al. Treatment of alcoholic fatty liver: is the metabolic effect of metadoxine the only reason for improved liver function? 1999 J. Hepatol. pmid:10207820
Petkova I et al. [Changes in renal enzyme activity in rats with experimental hypertension]. 1976 Eksp Med Morfol pmid:1021409
Viera AJ and Yates SW Toxic ingestion of gamma-hydroxybutyric acid. 1999 South. Med. J. pmid:10219359
Dimov D and Popov B Changes in blood-serum enzymes in rheumatic myocarditis. 1976 Cor Vasa pmid:1022412
MeniaÄ­lov NV and Shiverskaia VF [Effect of sodium hydroxybutyrate and neuroleptoanalgesic drugs on the accuracy of measurement of circulating blood volume using Evans blue]. 1976 Jul-Aug Eksp Khir Anesteziol pmid:1022450
Korfsmeier KH [Development of mammary gland. Histochemical study]. 1976 Verh Anat Ges pmid:1024388
Kurochkin IG and Tsikalova TS [Effect of sodium hydroxybutyrate, phenamine, transamine, l-DOPA on the physical work capacity of animals under multiple stress conditions]. 1976 Nov-Dec Farmakol Toksikol pmid:1024830
Shifrin GA et al. [Distribution of sodium hydroxybutyrate in the body following its intravenous administration]. 1976 Nov-Dec Farmakol Toksikol pmid:1024844
Bernasconi R et al. Gamma-hydroxybutyric acid: an endogenous neuromodulator with abuse potential? 1999 Trends Pharmacol. Sci. pmid:10322498
Badcock NR and Zotti R Rapid screening test for gamma-hydroxybutyric acid (GHB, Fantasy) in urine. 1999 Ther Drug Monit pmid:10365656
Yonekura K et al. UFT and its metabolites inhibit the angiogenesis induced by murine renal cell carcinoma, as determined by a dorsal air sac assay in mice. 1999 Clin. Cancer Res. pmid:10473104
Henne A et al. Construction of environmental DNA libraries in Escherichia coli and screening for the presence of genes conferring utilization of 4-hydroxybutyrate. 1999 Appl. Environ. Microbiol. pmid:10473393
Addolorato G et al. Long-term administration of GHB does not affect muscular mass in alcoholics. 1999 Life Sci. pmid:10530806
Davis LG Fatalities attributed to GHB and related compounds. 1999 South. Med. J. pmid:10548184
Addolorato G et al. Gamma-hydroxybutyric acid (GHB) in the treatment of alcohol withdrawal syndrome: a randomized comparative study versus benzodiazepine. 1999 Alcohol. Clin. Exp. Res. pmid:10549990
Lütke-Eversloh T and Steinbüchel A Biochemical and molecular characterization of a succinate semialdehyde dehydrogenase involved in the catabolism of 4-hydroxybutyric acid in Ralstonia eutropha. 1999 FEMS Microbiol. Lett. pmid:10564790
Yoon SC and Choi MH Local sequence dependence of polyhydroxyalkanoic acid degradation in Hydrogenophaga pseudoflava. 1999 J. Biol. Chem. pmid:10608842
Hofmann K et al. Sinorhizobium meliloti strain 1021 bioS and bdhA gene transcriptions are both affected by biotin available in defined medium. 2000 FEMS Microbiol. Lett. pmid:10612728
Valentin HE et al. Poly(3-hydroxybutyrate-co-4-hydroxybutyrate) formation from gamma-aminobutyrate and glutamate. 2000 Biotechnol. Bioeng. pmid:10620259
de L Costello AM et al. Neonatal hypoglycaemia in Nepal 2. Availability of alternative fuels. 2000 Arch. Dis. Child. Fetal Neonatal Ed. pmid:10634843
Craig K et al. Severe gamma-hydroxybutyrate withdrawal: a case report and literature review. 2000 J Emerg Med pmid:10645841
Silva AR et al. Inhibition of rat brain lipid synthesis in vitro by 4-hydroxybutyric acid. 1999 Metab Brain Dis pmid:10646691
Couper FJ and Logan BK Determination of gamma-hydroxybutyrate (GHB) in biological specimens by gas chromatography--mass spectrometry. 2000 Jan-Feb J Anal Toxicol pmid:10654561
Colombo G et al. Ability of baclofen in reducing alcohol intake and withdrawal severity: I--Preclinical evidence. 2000 Alcohol. Clin. Exp. Res. pmid:10656194
Vescovi PP and Pezzarossa A Thyrotropin-releasing hormone-induced GH release after cocaine withdrawal in cocaine addicts. 1999 Neuropeptides pmid:10657535
Basaki Y et al. [Anti-angiogenic activities of UFT and its metabolites, GHB and GBL, in the dorsal air sac (DAS) model in mice]. 2000 Gan To Kagaku Ryoho pmid:10660738
Volpi R et al. Muscarinic cholinergic mediation of the GH response to gamma-hydroxybutyric acid: neuroendocrine evidence in normal and parkinsonian subjects. 2000 Psychoneuroendocrinology pmid:10674281
Leblanc PJ and Ballantyne JS Novel aspects of the activities and subcellular distribution of enzymes of ketone body metabolism in the liver and kidney of the goldfish, Carassius auratus. 2000 J. Exp. Zool. pmid:10684566
Liang DS Value of enzyme studies after prostatic surgery. 1976 R I Med J pmid:1068498
Weiner AL Emerging drugs of abuse in Connecticut. 2000 Conn Med pmid:10697361
Hu RQ et al. Regulation of gamma-aminobutyric acid (GABA) release in cerebral cortex in the gamma-hydroxybutyric acid (GHB) model of absence seizures in rat. 2000 Neuropharmacology pmid:10698009
Wyss R et al. Determination of the N-methyl-D-aspartate receptor NR2B subunit blocker Ro 63-1908 in rat, cynomolgus monkey and human plasma by high-performance liquid chromatography with column switching and fluorescence detection. 2000 J Chromatogr A pmid:10722076
Al-Essa MA et al. Clinical, fluorine-18 labeled 2-fluoro-2-deoxyglucose positron emission tomography (FDG PET), MRI of the brain and biochemical observations in a patient with 4-hydroxybutyric aciduria; a progressive neurometabolic disease. 2000 Brain Dev. pmid:10722966
Elian AA A novel method for GHB detection in urine and its application in drug-facilitated sexual assaults. 2000 Forensic Sci. Int. pmid:10725654