4-hydroxy-butyric acid

4-hydroxy-butyric acid is a lipid of Fatty Acyls (FA) class.

Cross Reference

There are no associated biomedical information in the current reference collection.

Current reference collection contains 8613 references associated with 4-hydroxy-butyric acid in LipidPedia. Due to lack of full text of references or no associated biomedical terms are recognized in our current text-mining method, we cannot extract any biomedical terms related to diseases, pathways, locations, functions, genes, lipids, and animal models from the associated reference collection.

Users can download the reference list at the bottom of this page and read the reference manually to find out biomedical information.


Here are additional resources we collected from PubChem and MeSH for 4-hydroxy-butyric acid

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 4-hydroxy-butyric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Lung Neoplasms D008175 171 associated lipids
Inflammation D007249 119 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Arthritis D001168 41 associated lipids
Per page 10 20 50 100 | Total 113

PubChem Associated disorders and diseases

PubChem Biomolecular Interactions and Pathways

NCBI Entrez Crosslinks

All references with 4-hydroxy-butyric acid

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Per page 10 20 50 100 | Total 3045
Authors Title Published Journal PubMed Link
Ingels AS et al. Dried blood spot punches for confirmation of suspected γ-hydroxybutyric acid intoxications: validation of an optimized GC-MS procedure. 2011 Bioanalysis pmid:22011175
Thondorf I et al. Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1). 2011 Bioorg. Med. Chem. pmid:21955456
Zhou Q et al. Production of 3-hydroxypropionate homopolymer and poly(3-hydroxypropionate-co-4-hydroxybutyrate) copolymer by recombinant Escherichia coli. 2011 Metab. Eng. pmid:22024131
Esse K et al. Epidemic of illicit drug use, mechanisms of action/addiction and stroke as a health hazard. 2011 Brain Behav pmid:22398980
Vindrieux D et al. Down-regulation of DcR2 sensitizes androgen-dependent prostate cancer LNCaP cells to TRAIL-induced apoptosis. 2011 Cancer Cell Int. pmid:22136382
Aryal UK et al. Dynamic proteomic profiling of a unicellular cyanobacterium Cyanothece ATCC51142 across light-dark diurnal cycles. 2011 BMC Syst Biol pmid:22133144
Davis MM et al. Wild-type Drosophila melanogaster as a model host to analyze nitrogen source dependent virulence of Candida albicans. 2011 PLoS ONE pmid:22110651
Bowen MT et al. Adolescent oxytocin exposure causes persistent reductions in anxiety and alcohol consumption and enhances sociability in rats. 2011 PLoS ONE pmid:22110618
Kogoj D et al. Alpe adria report 2010 - conclusions and recommendations for the treatment of alcohol dependence. 2011 Front Psychiatry pmid:22065959
Chao Y and Zhang T Optimization of fixation methods for observation of bacterial cell morphology and surface ultrastructures by atomic force microscopy. 2011 Appl. Microbiol. Biotechnol. pmid:21881891
Yoshida K et al. B chromosomes have a functional effect on female sex determination in Lake Victoria cichlid fishes. 2011 PLoS Genet. pmid:21876673
Peng CH et al. A novel molecular signature identified by systems genetics approach predicts prognosis in oral squamous cell carcinoma. 2011 PLoS ONE pmid:21853135
Francis L et al. Controlled delivery of gentamicin using poly(3-hydroxybutyrate) microspheres. 2011 Int J Mol Sci pmid:21845079
Asad M et al. 2-[(E)-(2,4-Dichloro-benzyl-idene)amino]-isoindoline-1,3-dione. 2011 Acta Crystallogr Sect E Struct Rep Online pmid:21837105
Mendes AA et al. Immobilization of a Commercial Lipase from Penicillium camembertii (Lipase G) by Different Strategies. 2011 Enzyme Res pmid:21811674
Brummett CM and Clauw DJ Fibromyalgia: a primer for the anesthesia community. 2011 Curr Opin Anaesthesiol pmid:21799404
Fulton HG et al. The relationship between self-reported substance use and psychiatric symptoms in low-threshold methadone maintenance treatment clients. 2011 Harm Reduct J pmid:21798056
He JH et al. Allelic interaction of F1 pollen sterility loci and abnormal chromosome behaviour caused pollen sterility in intersubspecific autotetraploid rice hybrids. 2011 J. Exp. Bot. pmid:21624978
Park A and Stacy M Dopamine-induced nonmotor symptoms of Parkinson's disease. 2011 Parkinsons Dis pmid:21603184
Hunziker L et al. Rac1 deletion causes thymic atrophy. 2011 PLoS ONE pmid:21559396
Huang K et al. HYR1-mediated detoxification of reactive oxygen species is required for full virulence in the rice blast fungus. 2011 PLoS Pathog. pmid:21533213
El-Ansary AK et al. Plasma fatty acids as diagnostic markers in autistic patients from Saudi Arabia. 2011 Lipids Health Dis pmid:21510882
Chablais F et al. The zebrafish heart regenerates after cryoinjury-induced myocardial infarction. 2011 BMC Dev. Biol. pmid:21473762
Huang HC et al. Development of a sensitive long-wavelength fluorogenic probe for nitroreductase: a new fluorimetric indictor for analyte determination by dehydrogenase-coupled biosensors. 2011 Biosens Bioelectron pmid:21398106
Donjacour CE et al. Effect of sodium oxybate on growth hormone secretion in narcolepsy patients and healthy controls. 2011 Am. J. Physiol. Endocrinol. Metab. pmid:21447786
Minic Z and Thongbam PD The biological deep sea hydrothermal vent as a model to study carbon dioxide capturing enzymes. 2011 Mar Drugs pmid:21673885
Amato L et al. Efficacy and safety of pharmacological interventions for the treatment of the Alcohol Withdrawal Syndrome. 2011 Cochrane Database Syst Rev pmid:21678378
Chen Y et al. Reference values of biochemical and hematological parameters for Guizhou minipigs. 2011 Exp. Biol. Med. (Maywood) pmid:21427234
White H and Venkatesh B Clinical review: ketones and brain injury. 2011 Crit Care pmid:21489321
Chen X et al. Three homologous genes encoding sn-glycerol-3-phosphate acyltransferase 4 exhibit different expression patterns and functional divergence in Brassica napus. 2011 Plant Physiol. pmid:21173024
Engstrom EM et al. Arabidopsis homologs of the petunia hairy meristem gene are required for maintenance of shoot and root indeterminacy. 2011 Plant Physiol. pmid:21173022
Oleszczuk S et al. Aneuploidy among androgenic progeny of hexaploid triticale (XTriticosecale Wittmack). 2011 Plant Cell Rep. pmid:21170716
Dabbish NS and Raizen DM GABAergic synaptic plasticity during a developmentally regulated sleep-like state in C. elegans. 2011 J. Neurosci. pmid:22049436
Ellison CT et al. XAP5 CIRCADIAN TIMEKEEPER regulates ethylene responses in aerial tissues of Arabidopsis. 2011 Plant Physiol. pmid:21163961
Löbler M et al. Polymers and drugs suitable for the development of a drug delivery drainage system in glaucoma surgery. 2011 J. Biomed. Mater. Res. Part B Appl. Biomater. pmid:21432996
George CF et al. A 2-week, polysomnographic, safety study of sodium oxybate in obstructive sleep apnea syndrome. 2011 Sleep Breath pmid:20082240
Spitzer AR and Broadman M Treatment of the narcoleptiform sleep disorder in chronic fatigue syndrome and fibromyalgia with sodium oxybate. 2010 Jan-Feb Pain Pract pmid:20629967
Singh H et al. Antidepressant/anxiolytic and anti-nociceptive effects of novel 2-substituted 1,4-benzodiazepine-2-ones. 2010 Apr-Jun Sci Pharm pmid:21179341
Baeza C et al. Comparative karyotypic analysis in the Alstroemeria hookeri Lodd. (Alstroemeriaceae) complex sensu Bayer (1987). 2010 Genet. Mol. Biol. pmid:21637614
García de María C and Hueso Domínguez KB Simultaneous kinetic determination of 3-hydroxybutyrate and 3-hydroxyvalerate in biopolymer degradation processes. 2010 Talanta pmid:20006110
Peng Q et al. 1A6/DRIM, a novel t-UTP, activates RNA polymerase I transcription and promotes cell proliferation. 2010 PLoS ONE pmid:21151873
Pérez-García C et al. Chromosomal mapping of rRNA genes, core histone genes and telomeric sequences in Brachidontes puniceus and Brachidontes rodriguezi (Bivalvia, Mytilidae). 2010 BMC Genet. pmid:21143946
Janssen PJ et al. The complete genome sequence of Cupriavidus metallidurans strain CH34, a master survivalist in harsh and anthropogenic environments. 2010 PLoS ONE pmid:20463976
Moldofsky H et al. Effects of sodium oxybate on sleep physiology and sleep/wake-related symptoms in patients with fibromyalgia syndrome: a double-blind, randomized, placebo-controlled study. 2010 J. Rheumatol. pmid:20682669
Nasrallah FA et al. γ-Hydroxybutyrate and the GABAergic footprint: a metabolomic approach to unpicking the actions of GHB. 2010 J. Neurochem. pmid:20681954
Ding SL et al. The tig1 histone deacetylase complex regulates infectious growth in the rice blast fungus Magnaporthe oryzae. 2010 Plant Cell pmid:20675574
Dew BJ Toward a Better Understanding of Non-Addicted, Methamphetamine-Using, Men who Have Sex with Men (MSM) in Atlanta. 2010 Open AIDS J pmid:20657718
Yamamiya I et al. Formation pathways of gamma-butyrolactone from the furan ring of tegafur during its conversion to 5-fluorouracil. 2010 Drug Metab. Dispos. pmid:20463005
Arnoult N et al. Replication timing of human telomeres is chromosome arm-specific, influenced by subtelomeric structures and connected to nuclear localization. 2010 PLoS Genet. pmid:20421929
Carland F et al. The sterol methyltransferases SMT1, SMT2, and SMT3 influence Arabidopsis development through nonbrassinosteroid products. 2010 Plant Physiol. pmid:20421456