18194-25-7 is a lipid of Glycerophospholipids (GP) class. 18194-25-7 is associated with abnormalities such as gaucher's and Disorder, fluids. The involved functions are known as Force, Stereochemistry, Pressure- physical agent, van der Waals Attraction and Complication. 18194-25-7 often locates in Membrane, Tissue membrane, Head, Plasma membrane and Lipid Bilayers. The associated genes with 18194-25-7 are BHLHE41 gene. The related lipids are Liposomes, dilauroyl lecithin, lipid structure, 1,2-oleoylphosphatidylcholine and Unilamellar Vesicles.
To understand associated biological information of 18194-25-7, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
18194-25-7 is suspected in gaucher's, Disorder, fluids and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 18194-25-7
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Cough | D003371 | 19 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Enzootic Bovine Leukosis | D016583 | 2 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Blanck J et al. | Role of lipid in the electron transfer between NADPH-cytochrome P-450 reductase and cytochrome P-450 from mammalian liver cells. | 1989 | Xenobiotica | pmid:2515662 |
| Sessions-Bresnahan DR et al. | Validation of a heterologous fertilization assay and comparison of fertilization rates of equine oocytes using in vitro fertilization, perivitelline, and intracytoplasmic sperm injections. | 2014 | Theriogenology | pmid:24815920 |
| Landim-Alvarenga FC et al. | Penetration of zona-free hamster, bovine and equine oocytes by stallion and bull spermatozoa pretreated with equine follicular fluid, dilauroylphosphatidylcholine or calcium ionophore A23187. | 2001 | Theriogenology | pmid:11665894 |
| Mocé E et al. | Effect of sex-sorting on the ability of fresh and cryopreserved bull sperm to undergo an acrosome reaction. | 2006 | Theriogenology | pmid:16564078 |
| Abd E et al. | A Comparison of the Penetration and Permeation of Caffeine into and through Human Epidermis after Application in Various Vesicle Formulations. | 2016 | Skin Pharmacol Physiol | pmid:26540487 |
| Chiruvolu S et al. | Higher order self-assembly of vesicles by site-specific binding. | 1994 | Science | pmid:8209255 |
| Brake JM et al. | Biomolecular interactions at phospholipid-decorated surfaces of liquid crystals. | 2003 | Science | pmid:14684814 |
| Kraft ML et al. | Phase separation of lipid membranes analyzed with high-resolution secondary ion mass spectrometry. | 2006 | Science | pmid:17008528 |
| Ziegler C and Wessels JM | Investigation of lipid peroxidation in liposomes induced by heavy ion irradiation. | 1998 | Radiat Environ Biophys | pmid:9728741 |
| Chen SH et al. | Collective dynamics in fully hydrated phospholipid bilayers studied by inelastic x-ray scattering. | 2001 | Phys. Rev. Lett. | pmid:11177926 |
| Sengupta K et al. | Role of tilt order in the asymmetric ripple phase of phospholipid bilayers. | 2001 | Phys. Rev. Lett. | pmid:11497787 |
| Jeřábek P et al. | Lipid molecules can induce an opening of membrane-facing tunnels in cytochrome P450 1A2. | 2016 | Phys Chem Chem Phys | pmid:27722524 |
| Motegi T et al. | Single-molecule observations for determining the orientation and diffusivity of dye molecules in lipid bilayers. | 2013 | Phys Chem Chem Phys | pmid:23812281 |
| Singh RJ et al. | Photobleaching of merocyanine 540: involvement of singlet molecular oxygen. | 1992 | Photochem. Photobiol. | pmid:1620725 |
| Parasassi T et al. | Modulation and dynamics of phase properties in phospholipid mixtures detected by Laurdan fluorescence. | 1993 | Photochem. Photobiol. | pmid:8475171 |
| Chang TK et al. | Identification of the polymorphically expressed CYP2C19 and the wild-type CYP2C9-ILE359 allele as low-Km catalysts of cyclophosphamide and ifosfamide activation. | 1997 | Pharmacogenetics | pmid:9241661 |
| Ingraham HA | Metabolism: A lipid for fat disorders. | 2011 | Nature | pmid:21697939 |
| Lee JM et al. | A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects. | 2011 | Nature | pmid:21614002 |
| Musille PM et al. | Antidiabetic phospholipid-nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation. | 2012 | Nat. Struct. Mol. Biol. | pmid:22504882 |
| Lin CJ and Wang MC | Microbial metabolites regulate host lipid metabolism through NR5A-Hedgehog signalling. | 2017 | Nat. Cell Biol. | pmid:28436966 |
| Causey KM et al. | Dual role of phospholipid in the reconstitution of cytochrome P-450 LM2-dependent activities. | 1990 | Mol. Pharmacol. | pmid:2164629 |
| Perillo MA et al. | Modulation of phospholipases A2 and C activities against dilauroylphosphorylcholine in mixed monolayers with semisynthetic derivatives of ganglioside and sphingosine. | 1994 Apr-Jun | Mol. Membr. Biol. | pmid:7920864 |
| Lucy CA et al. | Surfactant-based methods for prevention of protein adsorption in capillary electrophoresis. | 2004 | Methods Mol. Biol. | pmid:15163850 |
| Bénarouche A et al. | Studying Gastric Lipase Adsorption Onto Phospholipid Monolayers by Surface Tensiometry, Ellipsometry, and Atomic Force Microscopy. | 2017 | Meth. Enzymol. | pmid:28063494 |
| Cosme J and Johnson EF | Analyzing binding of N-terminal truncated, microsomal cytochrome P450s to membranes. | 2002 | Meth. Enzymol. | pmid:12424903 |
| Helm CA and Israelachvili JN | Forces between phospholipid bilayers and relationship to membrane fusion. | 1993 | Meth. Enzymol. | pmid:8350750 |
| Meker S et al. | Amyloid-β Peptide Triggers Membrane Remodeling in Supported Lipid Bilayers Depending on Their Hydrophobic Thickness. | 2018 | Langmuir | pmid:30021071 |
| Singh A et al. | Phospholipid-assisted synthesis of stable F-containing colloidal particles and their film formation. | 2006 | Langmuir | pmid:16401097 |
| Bennun SV et al. | Molecular-scale structure in fluid-gel patterned bilayers: stability of interfaces and transmembrane distribution. | 2007 | Langmuir | pmid:17975936 |
| Adams DR et al. | Role of trehalose in prevention of giant vesicle adsorption and encapsulated solute leakage in anhydrobiotic preservation. | 2007 | Langmuir | pmid:17983248 |
| Tokumasu F et al. | Heterogeneous molecular distribution in supported multicomponent lipid bilayers. | 2004 | Langmuir | pmid:15773083 |
| Phang TL et al. | Displacement of fibrinogen from the air/aqueous interface by dilauroylphosphatidylcholine lipid. | 2005 | Langmuir | pmid:16229537 |
| Buboltz JT and Feigenson GW | Phospholipid solubility determined by equilibrium distribution between surface and bulk phases. | 2005 | Langmuir | pmid:15982034 |
| Phang TL et al. | Dynamic adsorption and surface tension of aqueous dilauroylphosphatidylcholine dispersions under physiological conditions. | 2004 | Langmuir | pmid:15969391 |
| Phang TL and Franses EI | Physically self-assembled monolayers (PSAMs) of lecithin lipids at hydrophilic silicon oxide interfaces. | 2006 | Langmuir | pmid:16460081 |
| Sen Mojumdar S et al. | Solvation dynamics under a microscope: single giant lipid vesicle. | 2012 | Langmuir | pmid:22703440 |
| Weinrich M et al. | Halothane changes the domain structure of a binary lipid membrane. | 2012 | Langmuir | pmid:22352350 |
| Bennun SV et al. | Drying and rehydration of DLPC/DSPC symmetric and asymmetric supported lipid bilayers: a combined AFM and fluorescence microscopy study. | 2008 | Langmuir | pmid:18707144 |
| Dittrich PS et al. | On-chip extrusion of lipid vesicles and tubes through microsized apertures. | 2006 | Lab Chip | pmid:16572210 |
| Tana S et al. | In vivo antitumor effect of cationic liposomes containing diphtheria toxin A-chain gene on cells infected with bovine leukemia virus. | 1997 | J. Vet. Med. Sci. | pmid:9271462 |
| Moon CP et al. | Overcoming hysteresis to attain reversible equilibrium folding for outer membrane phospholipase A in phospholipid bilayers. | 2011 | J. Mol. Biol. | pmid:21888919 |
| Whiles JA et al. | Methods for studying transmembrane peptides in bicelles: consequences of hydrophobic mismatch and peptide sequence. | 2002 Sep-Oct | J. Magn. Reson. | pmid:12419680 |
| Petrache HI et al. | Swelling of phospholipids by monovalent salt. | 2006 | J. Lipid Res. | pmid:16267342 |
| Holden CA and Trounson AO | Influence of a capacitation period on human sperm acrosome loss. | 1992 | J. Exp. Zool. | pmid:1460445 |
| Davis AP and Foote RH | Relationship of sire fertility to acrosome-reacted and motile spermatozoa after treatment with liposomes. | 1987 | J. Dairy Sci. | pmid:3584619 |
| Truelson SL et al. | In vitro penetration into bovine oocytes and zona-free hamster oocytes by bull spermatozoa treated with liposomes. | 1996 | J. Dairy Sci. | pmid:8827462 |
| Iyer BR et al. | Energetics of side-chain partitioning of β-signal residues in unassisted folding of a transmembrane β-barrel protein. | 2017 | J. Biol. Chem. | pmid:28592485 |
| Cooke GM and Robaire B | Modulation of epididymal delta 4-steroid 5 alpha-reductase activity in vitro by the phospholipid environment. | 1985 | J. Biol. Chem. | pmid:3997884 |
| Seddon JM et al. | Metastability and polymorphism in the gel and fluid bilayer phases of dilauroylphosphatidylethanolamine. Two crystalline forms in excess water. | 1983 | J. Biol. Chem. | pmid:6833234 |
| Parasassi T et al. | Detection of phospholipid phase separation. A multifrequency phase fluorimetry study of 1,6-diphenyl-1,3,5-hexatriene fluorescence. | 1984 | J. Biol. Chem. | pmid:6548746 |
| Korshavn KJ et al. | Reduced Lipid Bilayer Thickness Regulates the Aggregation and Cytotoxicity of Amyloid-β. | 2017 | J. Biol. Chem. | pmid:28154182 |
| Rothgeb TM and Oldfield E | Nitrogen-14 nuclear magnetic resonance spectroscopy as a probe of lipid bilayer headgroup structure. | 1981 | J. Biol. Chem. | pmid:6894596 |
| Cosme J and Johnson EF | Engineering microsomal cytochrome P450 2C5 to be a soluble, monomeric enzyme. Mutations that alter aggregation, phospholipid dependence of catalysis, and membrane binding. | 2000 | J. Biol. Chem. | pmid:10644712 |
| Firozi PF and Bhattacharya RK | Effects of natural polyphenols on aflatoxin B1 activation in a reconstituted microsomal monooxygenase system. | 1995 | J. Biochem. Toxicol. | pmid:7595929 |
| Sui SF and Sackmann E | Interaction of glycophorin with lipid bilayer studied by calorimetry, densitometry, static light scattering, and electron microscopy. | 1992 | J. Biochem. | pmid:1607359 |
| Yokota H et al. | Differential effects of phospholipids on two similar forms of UDP-glucuronyltransferase purified from rat liver and kidney microsomes. | 1991 | J. Biochem. | pmid:1939026 |
| Kojima H et al. | Purification and characterization of NADPH-cytochrome c reductase from porcine polymorphonuclear leukocytes. | 1987 | J. Biochem. | pmid:3125159 |
| Takahashi K et al. | Release of vesicles containing acetylcholinesterase from erythrocyte membranes by treatment with dilauroylglycerophosphocholine. | 1983 | J. Biochem. | pmid:6885744 |
| Tamura A et al. | Interaction of added amphiphilic lipids with the membrane of intact human erythrocytes to induce change in the cell shape. | 1982 | J. Biochem. | pmid:6917846 |
| Holden CA and Trounson AO | Effect of dilauroylphosphatidylcholine on human spermatozoa. | 1992 May-Jun | J. Androl. | pmid:1601746 |
| Howland MC et al. | Phospholipid morphologies on photochemically patterned silane monolayers. | 2005 | J. Am. Chem. Soc. | pmid:15869298 |
| Zhao W et al. | Water at the surfaces of aligned phospholipid multibilayer model membranes probed with ultrafast vibrational spectroscopy. | 2008 | J. Am. Chem. Soc. | pmid:18823116 |
| Meli MV et al. | Preparation of microscopic and planar oil-water interfaces that are decorated with prescribed densities of insoluble amphiphiles. | 2008 | J. Am. Chem. Soc. | pmid:18335929 |
| Moraille P and Badia A | Enzymatic lithography of phospholipid bilayer films by stereoselective hydrolysis. | 2005 | J. Am. Chem. Soc. | pmid:15869271 |
| Vostrikov VV et al. | Comparison of "Polarization inversion with spin exchange at magic angle" and "geometric analysis of labeled alanines" methods for transmembrane helix alignment. | 2008 | J. Am. Chem. Soc. | pmid:18763771 |
| Marasinghe PA et al. | Membrane curvature change induced by an antimicrobial peptide detected by 31P exchange NMR. | 2005 | J Phys Chem B | pmid:16853861 |
| Pan J and Khadka NK | Kinetic Defects Induced by Melittin in Model Lipid Membranes: A Solution Atomic Force Microscopy Study. | 2016 | J Phys Chem B | pmid:27167473 |
| Gobrogge CA et al. | Temperature-Dependent Partitioning of Coumarin 152 in Phosphatidylcholine Lipid Bilayers. | 2017 | J Phys Chem B | pmid:28350163 |
| Goertz MP et al. | Nanomechanical contrasts of gel and fluid phase supported lipid bilayers. | 2009 | J Phys Chem B | pmid:19534482 |
| Zhang Z and Berkowitz ML | Orientational dynamics of water in phospholipid bilayers with different hydration levels. | 2009 | J Phys Chem B | pmid:19413360 |
| Beales PA and Vanderlick TK | Partitioning of membrane-anchored DNA between coexisting lipid phases. | 2009 | J Phys Chem B | pmid:19827842 |
| Bennun SV et al. | Phase and mixing behavior in two-component lipid bilayers: a molecular dynamics study in DLPC/DSPC mixtures. | 2007 | J Phys Chem B | pmid:17636980 |
| de Joannis J et al. | Equilibrium distributions of dipalmitoyl phosphatidylcholine and dilauroyl phosphatidylcholine in a mixed lipid bilayer: atomistic semigrand canonical ensemble simulations. | 2006 | J Phys Chem B | pmid:17181235 |
| Nitschke WK et al. | Molecular dynamics investigations of PRODAN in a DLPC bilayer. | 2012 | J Phys Chem B | pmid:22329741 |
| Srividya N et al. | Determination of the line tension of giant vesicles from pore-closing dynamics. | 2008 | J Phys Chem B | pmid:18503265 |
| Lotan O et al. | Critical Conditions for Adsorption of Calcium Ions onto Dipolar Lipid Membranes. | 2016 | J Phys Chem A | pmid:27128099 |
| Oguchi T et al. | DSPC/DLPC mixed films supported on silica: a QCM-D and friction force study. | 2011 | J Oleo Sci | pmid:21427514 |
| Costello MJ et al. | Simple procedures for evaluating the cryofixation of biological samples. | 1982 | J Microsc | pmid:7086878 |
| Lopes S and Castanho MA | Does aliphatic chain length influence carbocyanines' orientation in supported lipid multilayers? | 2004 | J Fluoresc | pmid:15615210 |
| Inoue T et al. | Surface adsorption and vesicle formation of dilauroylphosphatidylcholine in room temperature ionic liquids. | 2012 | J Colloid Interface Sci | pmid:22542478 |
| Li H et al. | Drude Polarizable Force Field for Molecular Dynamics Simulations of Saturated and Unsaturated Zwitterionic Lipids. | 2017 | J Chem Theory Comput | pmid:28731702 |
| Kopelevich DI and Nagle JF | Correlation between length and tilt of lipid tails. | 2015 | J Chem Phys | pmid:26493917 |
| Gruenbaum SM and Skinner JL | Vibrational spectroscopy of water in hydrated lipid multi-bilayers. I. Infrared spectra and ultrafast pump-probe observables. | 2011 | J Chem Phys | pmid:21861584 |
| Zhang L and Granick S | Lipid diffusion compared in outer and inner leaflets of planar supported bilayers. | 2005 | J Chem Phys | pmid:16356031 |
| Sugii T et al. | A molecular-dynamics study of lipid bilayers: effects of the hydrocarbon chain length on permeability. | 2005 | J Chem Phys | pmid:16292928 |
| Gruenbaum SM et al. | Vibrational spectroscopy of water in hydrated lipid multi-bilayers. II. Two-dimensional infrared and peak shift observables within different theoretical approximations. | 2011 | J Chem Phys | pmid:22047251 |
| Skiba-Lahiani M et al. | Stimulation of movement and acrosome reaction of human spermatozoa by PC12 liposomes encapsulating ATP. | 1995 | Int. J. Androl. | pmid:8719844 |
| Shan W et al. | Systematic evaluation of the toxicity and biodistribution of virus mimicking mucus-penetrating DLPC-NPs as oral drug delivery system. | 2017 | Int J Pharm | pmid:28743553 |
| Saari M et al. | Pulmonary distribution and clearance of two beclomethasone liposome formulations in healthy volunteers. | 1999 | Int J Pharm | pmid:10370197 |
| Knudsen NØ et al. | Targeting of liposome-associated calcipotriol to the skin: effect of liposomal membrane fluidity and skin barrier integrity. | 2011 | Int J Pharm | pmid:21419203 |
| Stiborová M et al. | Cytochromes P450 2B1 and P450 2B2 demethylate N-nitrosodimethylamine and N-nitrosomethylaniline in vitro. | 1996 | Gen. Physiol. Biophys. | pmid:9076504 |
| Omata Y and Friedman FK | The effect of dilauroyl-L-3-phosphatidylcholine on the interaction between cytochrome P-450 1A1 and benzo[a]pyrene. | 1992 | FEBS Lett. | pmid:1516694 |
| Mithöfer A and Ebel J | Functional reconstitution of beta-glucan elicitor-binding activity upon incorporation into lipid vesicles. | 1999 | FEBS Lett. | pmid:10481050 |
| Borioli GA et al. | Phospholipase activity is modulated by c-Fos through substrate expansion and hyperpolarization. | 2004 | FEBS Lett. | pmid:15251444 |
| Balvers WG et al. | Kinetics of cytochromes P-450 IA1 and IIB1 in reconstituted systems with dilauroyl- and distearoyl-glycerophosphocholine. | 1993 | Eur. J. Biochem. | pmid:8344304 |
| Rietjens IM et al. | On the role of phospholipids in the reconstituted cytochrome P-450 system. A model study using dilauroyl and distearoyl glycerophosphocholine. | 1989 | Eur. J. Biochem. | pmid:2496984 |
| Naydenova S et al. | Pure and mixed lipid black foam films as models of membrane fusion. | 1990 | Eur. Biophys. J. | pmid:2307142 |
| Marius P et al. | Probing the oligomeric state and interaction surfaces of Fukutin-I in dilauroylphosphatidylcholine bilayers. | 2012 | Eur. Biophys. J. | pmid:22075563 |
| Vitkova V et al. | Alamethicin influence on the membrane bending elasticity. | 2006 | Eur. Biophys. J. | pmid:16211403 |
| Kumar V et al. | Amiodarone analog-dependent effects on CYP2C9-mediated metabolism and kinetic profiles. | 2006 | Drug Metab. Dispos. | pmid:16815961 |