18194-25-7 is a lipid of Glycerophospholipids (GP) class. 18194-25-7 is associated with abnormalities such as gaucher's and Disorder, fluids. The involved functions are known as Force, Stereochemistry, Pressure- physical agent, van der Waals Attraction and Complication. 18194-25-7 often locates in Membrane, Tissue membrane, Head, Plasma membrane and Lipid Bilayers. The associated genes with 18194-25-7 are BHLHE41 gene. The related lipids are Liposomes, dilauroyl lecithin, lipid structure, 1,2-oleoylphosphatidylcholine and Unilamellar Vesicles.
To understand associated biological information of 18194-25-7, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
18194-25-7 is suspected in gaucher's, Disorder, fluids and other diseases in descending order of the highest number of associated sentences.
| Disease | Cross reference | Weighted score | Related literature |
|---|
We collected disease MeSH terms mapped to the references associated with 18194-25-7
| MeSH term | MeSH ID | Detail |
|---|---|---|
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Mammary Neoplasms, Experimental | D008325 | 67 associated lipids |
| Body Weight | D001835 | 333 associated lipids |
| Cough | D003371 | 19 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Enzootic Bovine Leukosis | D016583 | 2 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
| Location | Cross reference | Weighted score | Related literatures |
|---|
| Function | Cross reference | Weighted score | Related literatures |
|---|
| Lipid concept | Cross reference | Weighted score | Related literatures |
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| Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sengupta K et al. | Role of tilt order in the asymmetric ripple phase of phospholipid bilayers. | 2001 | Phys. Rev. Lett. | pmid:11497787 |
| Jeřábek P et al. | Lipid molecules can induce an opening of membrane-facing tunnels in cytochrome P450 1A2. | 2016 | Phys Chem Chem Phys | pmid:27722524 |
| Motegi T et al. | Single-molecule observations for determining the orientation and diffusivity of dye molecules in lipid bilayers. | 2013 | Phys Chem Chem Phys | pmid:23812281 |
| Singh RJ et al. | Photobleaching of merocyanine 540: involvement of singlet molecular oxygen. | 1992 | Photochem. Photobiol. | pmid:1620725 |
| Parasassi T et al. | Modulation and dynamics of phase properties in phospholipid mixtures detected by Laurdan fluorescence. | 1993 | Photochem. Photobiol. | pmid:8475171 |
| Chang TK et al. | Identification of the polymorphically expressed CYP2C19 and the wild-type CYP2C9-ILE359 allele as low-Km catalysts of cyclophosphamide and ifosfamide activation. | 1997 | Pharmacogenetics | pmid:9241661 |
| Ingraham HA | Metabolism: A lipid for fat disorders. | 2011 | Nature | pmid:21697939 |
| Lee JM et al. | A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects. | 2011 | Nature | pmid:21614002 |
| Musille PM et al. | Antidiabetic phospholipid-nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation. | 2012 | Nat. Struct. Mol. Biol. | pmid:22504882 |
| Lin CJ and Wang MC | Microbial metabolites regulate host lipid metabolism through NR5A-Hedgehog signalling. | 2017 | Nat. Cell Biol. | pmid:28436966 |