18194-24-6

18194-24-6 is a lipid of Glycerophospholipids (GP) class. 18194-24-6 is associated with abnormalities such as Cerebrovascular accident, Renal tubular disorder, Atherosclerosis, Hyperlipoproteinemia Type III and Lipid Metabolism Disorders. The involved functions are known as Process, protein folding, Catalyst, Biochemical Pathway and Fold in Medical Device Material. 18194-24-6 often locates in Tissue membrane, Membrane, periplasm, vesicle membrane and outer membrane. The associated genes with 18194-24-6 are Integral Membrane Proteins, Protein Structure, RTN4 gene, RTN4R gene and Protein, Organized by Structure. The related lipids are Micelles, dimyristoylphosphatidylglycerol, 1,2-dihexadecyl-sn-glycero-3-phosphocholine, Unilamellar Vesicles and cholesteryl oleate. The related experimental models are Mouse Model, Arthritis, Adjuvant-Induced, Disease model and Xenograft Model.

Cross Reference

Introduction

To understand associated biological information of 18194-24-6, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 18194-24-6?

18194-24-6 is suspected in Atherosclerosis, Cardiovascular Diseases, Dehydration, Abnormal shape, Renal tubular disorder, Hyperlipoproteinemia Type III and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 18194-24-6

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Adenocarcinoma D000230 166 associated lipids
Lung Neoplasms D008175 171 associated lipids
Body Weight D001835 333 associated lipids
Carcinoma D002277 18 associated lipids
Osteosarcoma D012516 50 associated lipids
Lymphoma, Large B-Cell, Diffuse D016403 13 associated lipids
Chemical and Drug Induced Liver Injury D056486 39 associated lipids
Alzheimer Disease D000544 76 associated lipids
Arteriosclerosis D001161 86 associated lipids
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
Colorectal Neoplasms D015179 10 associated lipids
Anemia, Hemolytic, Congenital D000745 5 associated lipids
Hyperlipoproteinemias D006951 15 associated lipids
Tangier Disease D013631 8 associated lipids
HIV Infections D015658 20 associated lipids
Carcinoma, Non-Small-Cell Lung D002289 72 associated lipids
Mycoses D009181 18 associated lipids
Cholangiocarcinoma D018281 7 associated lipids
Per page 10 20 50 | Total 22

PubChem Associated disorders and diseases

What pathways are associated with 18194-24-6

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 18194-24-6?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with 18194-24-6?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 18194-24-6?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with 18194-24-6?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 18194-24-6?

Mouse Model

Mouse Model are used in the study 'Association of a model class A (apolipoprotein) amphipathic alpha helical peptide with lipid: high resolution NMR studies of peptide.lipid discoidal complexes.' (Mishra VK et al., 2006).

Arthritis, Adjuvant-Induced

Arthritis, Adjuvant-Induced are used in the study 'T cell antigen receptor peptide-lipid membrane interactions using surface plasmon resonance.' (Bender V et al., 2004).

Disease model

Disease model are used in the study 'Kupffer cells do not play a role in governing the efficacy of liposomal mitoxantrone used to treat a tumor model designed to assess drug delivery to liver.' (Lim HJ et al., 2000).

Related references are published most in these journals:

Model Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

NCBI Entrez Crosslinks

All references with 18194-24-6

Download all related citations
Per page 10 20 50 100 | Total 3218
Authors Title Published Journal PubMed Link
Kim H et al. Cross-polarization schemes for peptide samples oriented in hydrated phospholipid bilayers. 2004 J. Magn. Reson. pmid:15082260
Glaser RW et al. Orientation of the antimicrobial peptide PGLa in lipid membranes determined from 19F-NMR dipolar couplings of 4-CF3-phenylglycine labels. 2004 J. Magn. Reson. pmid:15082261
Nusair NA et al. Investigating fatty acids inserted into magnetically aligned phospholipid bilayers using EPR and solid-state NMR spectroscopy. 2004 J. Magn. Reson. pmid:15140432
Hisao GS et al. An efficient method and device for transfer of semisolid materials into solid-state NMR spectroscopy rotors. 2016 J. Magn. Reson. pmid:26905816
Tesch DM and Nevzorov AA Sensitivity enhancement and contrasting information provided by free radicals in oriented-sample NMR of bicelle-reconstituted membrane proteins. 2014 J. Magn. Reson. pmid:24355622
Prosser RS et al. Lanthanide chelates as bilayer alignment tools in NMR studies of membrane-associated peptides. 1999 J. Magn. Reson. pmid:10579948
Gröbner G et al. Probing membrane surfaces and the location of membrane-embedded peptides by (13)C MAS NMR using lanthanide ions. 1999 J. Magn. Reson. pmid:10579957
Mangels ML et al. Investigating magnetically aligned phospholipid bilayers with EPR spectroscopy at 94 GHz. 2001 J. Magn. Reson. pmid:11531347
Whiles JA et al. Methods for studying transmembrane peptides in bicelles: consequences of hydrophobic mismatch and peptide sequence. 2002 Sep-Oct J. Magn. Reson. pmid:12419680
Mainali L et al. Membrane fluidity profiles as deduced by saturation-recovery EPR measurements of spin-lattice relaxation times of spin labels. 2011 J. Magn. Reson. pmid:21868272
Gorfe AA et al. Structure and dynamics of the full-length lipid-modified H-Ras protein in a 1,2-dimyristoylglycero-3-phosphocholine bilayer. 2007 J. Med. Chem. pmid:17263520
Kolocouris A et al. Interaction between an amantadine analogue and the transmembrane portion of the influenza A M2 protein in liposomes probed by 1H NMR spectroscopy of the ligand. 2004 J. Med. Chem. pmid:15369403
Salgado GF et al. The role of membranes in the organization of HIV-1 Gag p6 and Vpr: p6 shows high affinity for membrane bilayers which substantially increases the interaction between p6 and Vpr. 2009 J. Med. Chem. pmid:19883084
Bom D et al. Novel A,B,E-ring-modified camptothecins displaying high lipophilicity and markedly improved human blood stabilities. 1999 J. Med. Chem. pmid:10447944
Bombelli C et al. Efficient transfection of DNA by liposomes formulated with cationic gemini amphiphiles. 2005 J. Med. Chem. pmid:16078856
Khokhar AR et al. Chemical and biological studies on a series of lipid-soluble (trans-(R,R)- and -(S,S)-1,2-diaminocyclohexane)platinum(II) complexes incorporated in liposomes. 1991 J. Med. Chem. pmid:1992134
Bombelli C et al. Inclusion of a photosensitizer in liposomes formed by DMPC/gemini surfactant: correlation between physicochemical and biological features of the complexes. 2005 J. Med. Chem. pmid:16033268
Bombelli C et al. PEGylated lipoplexes: preparation protocols affecting DNA condensation and cell transfection efficiency. 2007 J. Med. Chem. pmid:17973357
Boni LT et al. Alterations in phospholipid polymorphism by polyethylene glycol. 1984 J. Membr. Biol. pmid:6481795
Ishii N Two-dimensional crystalline array formation of glucuronide transporter from Escherichia coli by the use of polystyrene beads for detergent removal. 2013 J. Membr. Biol. pmid:23188061
Xiang TX and Anderson BD Phospholipid surface density determines the partitioning and permeability of acetic acid in DMPC:cholesterol bilayers. 1995 J. Membr. Biol. pmid:8606364
Suwalsky M et al. Effects of Thimerosal on Lipid Bilayers and Human Erythrocytes: An In Vitro Study. 2016 J. Membr. Biol. pmid:27738716
Upadhyay SK et al. Insights from Micro-second Atomistic Simulations of Melittin in Thin Lipid Bilayers. 2015 J. Membr. Biol. pmid:25963936
Chehín RN et al. Differential transmembrane diffusion of triiodothyronine and thyroxine in liposomes: regulation by lipid composition. 1999 J. Membr. Biol. pmid:9929377
Vad BS et al. Phospholipid Ether Linkages Significantly Modulate the Membrane Affinity of the Antimicrobial Peptide Novicidin. 2015 J. Membr. Biol. pmid:25801603
Suwalsky M et al. Morphological Effects Induced In Vitro by Propranolol on Human Erythrocytes. 2015 J. Membr. Biol. pmid:25724773
Perrier-Cornet JM et al. Pressure-induced shape change of phospholipid vesicles: implication of compression and phase transition. 2005 J. Membr. Biol. pmid:16245032
Cutró AC et al. Effect of phloretin on the binding of 1-anilino-8-naphtalene sulfonate (ANS) to 1,2-Dimyristoyl-sn-glycero-3-phosphocoline (DMPC) vesicles in the gel and liquid-crystalline state. 2015 J. Membr. Biol. pmid:25380679
Ferreira M and Gameiro P Ciprofloxacin metalloantibiotic: an effective antibiotic with an influx route strongly dependent on lipid interaction? 2015 J. Membr. Biol. pmid:25378125
Gershfeld NL and Ginsberg L Probing the critical unilamellar state of membranes. 1997 J. Membr. Biol. pmid:9096068
Suwalsky M et al. An In Vitro Study of the Antioxidant and Antihemolytic Properties of Buddleja globosa (Matico). 2017 J. Membr. Biol. pmid:28386629
Ahmed M et al. Thermodynamics of partitioning and efflux of phenothiazines from liposomes. 1981 J. Membr. Biol. pmid:7218338
Pinisetty D et al. A molecular dynamics study of DMPC lipid bilayers interacting with dimethylsulfoxide-water mixtures. 2012 J. Membr. Biol. pmid:22836671
Perrin BS et al. The Curvature Induction of Surface-Bound Antimicrobial Peptides Piscidin 1 and Piscidin 3 Varies with Lipid Chain Length. 2015 J. Membr. Biol. pmid:25292264
Gross E et al. Effects of membrane physical parameters on hematoporphyrin-derivative binding to liposomes: a spectroscopic study. 1987 J. Membr. Biol. pmid:2957505
Farías RN et al. Differential effect of triiodothyronine and thyroxine on the liposomal membrane in liquid-crystalline and gel state. 1995 J. Membr. Biol. pmid:7731033
Tsiotis G et al. Tubular crystals of a photosystem II core complex. 1996 J. Mol. Biol. pmid:8656426
Dolder M et al. Human erythrocyte band 3. Solubilization and reconstitution into two-dimensional crystals. 1993 J. Mol. Biol. pmid:8496957
Petrache HI et al. Modulation of glycophorin A transmembrane helix interactions by lipid bilayers: molecular dynamics calculations. 2000 J. Mol. Biol. pmid:10986130
Bokvist M et al. Two types of Alzheimer's beta-amyloid (1-40) peptide membrane interactions: aggregation preventing transmembrane anchoring versus accelerated surface fibril formation. 2004 J. Mol. Biol. pmid:14698298
Doherty T et al. High-resolution orientation and depth of insertion of the voltage-sensing S4 helix of a potassium channel in lipid bilayers. 2010 J. Mol. Biol. pmid:20600109
Hunt JF et al. Assessment of the aggregation state of integral membrane proteins in reconstituted phospholipid vesicles using small angle neutron scattering. 1997 J. Mol. Biol. pmid:9367787
Kovacs FA et al. Helix tilt of the M2 transmembrane peptide from influenza A virus: an intrinsic property. 2000 J. Mol. Biol. pmid:10623512
Dorset DL et al. Two-dimensional crystal packing of matrix porin. A channel forming protein in Escherichia coli outer membranes. 1983 J. Mol. Biol. pmid:6304320
Li L et al. Double belt structure of discoidal high density lipoproteins: molecular basis for size heterogeneity. 2004 J. Mol. Biol. pmid:15491614
Smith SO et al. Helical structure of phospholamban in membrane bilayers. 2001 J. Mol. Biol. pmid:11700069
Kim JM et al. Structure and function in bacteriorhodopsin: the role of the interhelical loops in the folding and stability of bacteriorhodopsin. 2001 J. Mol. Biol. pmid:11327776
Allen SJ et al. Structure and function in bacteriorhodopsin: the effect of the interhelical loops on the protein folding kinetics. 2001 J. Mol. Biol. pmid:11327777
Sahoo D et al. Lipid-triggered conformational switch of apolipophorin III helix bundle to an extended helix organization. 2002 J. Mol. Biol. pmid:12144779
Jap BK and Li H Structure of the osmo-regulated H2O-channel, AQP-CHIP, in projection at 3.5 A resolution. 1995 J. Mol. Biol. pmid:7544415