18194-24-6 is a lipid of Glycerophospholipids (GP) class. 18194-24-6 is associated with abnormalities such as Cerebrovascular accident, Renal tubular disorder, Atherosclerosis, Hyperlipoproteinemia Type III and Lipid Metabolism Disorders. The involved functions are known as Process, protein folding, Catalyst, Biochemical Pathway and Fold in Medical Device Material. 18194-24-6 often locates in Tissue membrane, Membrane, periplasm, vesicle membrane and outer membrane. The associated genes with 18194-24-6 are Integral Membrane Proteins, Protein Structure, RTN4 gene, RTN4R gene and Protein, Organized by Structure. The related lipids are Micelles, dimyristoylphosphatidylglycerol, 1,2-dihexadecyl-sn-glycero-3-phosphocholine, Unilamellar Vesicles and cholesteryl oleate. The related experimental models are Mouse Model, Arthritis, Adjuvant-Induced, Disease model and Xenograft Model.
To understand associated biological information of 18194-24-6, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
18194-24-6 is suspected in Atherosclerosis, Cardiovascular Diseases, Dehydration, Abnormal shape, Renal tubular disorder, Hyperlipoproteinemia Type III and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with 18194-24-6
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Mouse Model are used in the study 'Association of a model class A (apolipoprotein) amphipathic alpha helical peptide with lipid: high resolution NMR studies of peptide.lipid discoidal complexes.' (Mishra VK et al., 2006).
Arthritis, Adjuvant-Induced are used in the study 'T cell antigen receptor peptide-lipid membrane interactions using surface plasmon resonance.' (Bender V et al., 2004).
Disease model are used in the study 'Kupffer cells do not play a role in governing the efficacy of liposomal mitoxantrone used to treat a tumor model designed to assess drug delivery to liver.' (Lim HJ et al., 2000).
Model | Cross reference | Weighted score | Related literatures |
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Authors | Title | Published | Journal | PubMed Link |
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Curnow P and Booth PJ | Combined kinetic and thermodynamic analysis of alpha-helical membrane protein unfolding. | 2007 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18025476 |
Surrey T and Jähnig F | Refolding and oriented insertion of a membrane protein into a lipid bilayer. | 1992 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1502158 |
Tang P and Xu Y | Large-scale molecular dynamics simulations of general anesthetic effects on the ion channel in the fully hydrated membrane: the implication of molecular mechanisms of general anesthesia. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12438684 |
Popp CA and Hyde JS | Electron-electron double resonance and saturation-recovery studies of nitroxide electron and nuclear spin-lattice relaxation times and Heisenberg exchange rates: lateral diffusion in dimyristoyl phosphatidylcholine. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6283533 |
Pownall HJ et al. | Activation of lecithin:cholesterol acyltransferase by a synthetic model lipid-associating peptide. | 1980 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6774331 |
Villinger S et al. | Functional dynamics in the voltage-dependent anion channel. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21148773 |
Radhakrishnan A and McConnell HM | Electric field effect on cholesterol-phospholipid complexes. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10655486 |
Kalyanaraman B et al. | Photodynamic action of merocyanine 540 on artificial and natural cell membranes: involvement of singlet molecular oxygen. | 1987 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3033673 |
de Meyer F and Smit B | Effect of cholesterol on the structure of a phospholipid bilayer. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19225105 |
Dornmair K and Jähnig F | Internal dynamics of lactose permease. | 1989 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2690075 |