MeSH term | MeSH ID | Detail |
---|---|---|
Anemia, Hemolytic, Congenital | D000745 | 5 associated lipids |
Lymphoma, Primary Effusion | D054685 | 2 associated lipids |
18194-24-6 is a lipid of Glycerophospholipids (GP) class. 18194-24-6 is associated with abnormalities such as Cerebrovascular accident, Renal tubular disorder, Atherosclerosis, Hyperlipoproteinemia Type III and Lipid Metabolism Disorders. The involved functions are known as Process, protein folding, Catalyst, Biochemical Pathway and Fold in Medical Device Material. 18194-24-6 often locates in Tissue membrane, Membrane, periplasm, vesicle membrane and outer membrane. The associated genes with 18194-24-6 are Integral Membrane Proteins, Protein Structure, RTN4 gene, RTN4R gene and Protein, Organized by Structure. The related lipids are Micelles, dimyristoylphosphatidylglycerol, 1,2-dihexadecyl-sn-glycero-3-phosphocholine, Unilamellar Vesicles and cholesteryl oleate. The related experimental models are Mouse Model, Arthritis, Adjuvant-Induced, Disease model and Xenograft Model.
To understand associated biological information of 18194-24-6, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
18194-24-6 is suspected in Atherosclerosis, Cardiovascular Diseases, Dehydration, Abnormal shape, Renal tubular disorder, Hyperlipoproteinemia Type III and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with 18194-24-6
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
Mouse Model are used in the study 'Association of a model class A (apolipoprotein) amphipathic alpha helical peptide with lipid: high resolution NMR studies of peptide.lipid discoidal complexes.' (Mishra VK et al., 2006).
Arthritis, Adjuvant-Induced are used in the study 'T cell antigen receptor peptide-lipid membrane interactions using surface plasmon resonance.' (Bender V et al., 2004).
Disease model are used in the study 'Kupffer cells do not play a role in governing the efficacy of liposomal mitoxantrone used to treat a tumor model designed to assess drug delivery to liver.' (Lim HJ et al., 2000).
Model | Cross reference | Weighted score | Related literatures |
---|
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Bogusky MJ et al. | Comparison of the dynamics of the membrane-bound form of fd coat protein in micelles and in bilayers by solution and solid-state nitrogen-15 nuclear magnetic resonance spectroscopy. | 1988 | Proteins | pmid:3227013 |
Cascio M and Wallace BA | Conformation of alamethicin in phospholipid vesicles: implications for insertion models. | 1988 | Proteins | pmid:3227017 |
Veldkamp CT et al. | Monomeric structure of the cardioprotective chemokine SDF-1/CXCL12. | 2009 | Protein Sci. | pmid:19551879 |
Páli T et al. | Stoichiometry of lipid interactions with transmembrane proteins--Deduced from the 3D structures. | 2006 | Protein Sci. | pmid:16641489 |
Shin I et al. | Interaction of partially unfolded forms of Torpedo acetylcholinesterase with liposomes. | 1996 | Protein Sci. | pmid:8771195 |
Min D et al. | A simple DNA handle attachment method for single molecule mechanical manipulation experiments. | 2016 | Protein Sci. | pmid:27222403 |
Gan SW et al. | The transmembrane homotrimer of ADAM 1 in model lipid bilayers. | 2007 | Protein Sci. | pmid:17189481 |
Faham S et al. | Crystallization of bacteriorhodopsin from bicelle formulations at room temperature. | 2005 | Protein Sci. | pmid:15689517 |
Kun H and Mastai Y | Isothermal calorimetry study of the interactions of type I antifreeze proteins with a lipid model membrane. | 2010 | Protein Pept. Lett. | pmid:19995337 |
Watanabe L et al. | Initiating structural studies of Lys49-PLA2 homologues complexed with an anionic detergent, a fatty acid and a natural lipid. | 2003 | Protein Pept. Lett. | pmid:14561144 |
Prakash P and Sankararamakrishnan R | Molecular dynamics simulations of C-terminal decapeptide of gastrin-releasing peptide in DMPC bilayers: structure, stability and orientation of the peptide hormone within the bilayers. | 2007 | Protein Pept. Lett. | pmid:17627601 |
Pillot T et al. | Single-step purification of two functional human apolipoprotein E variants hyperexpressed in Escherichia coli. | 1996 | Protein Expr. Purif. | pmid:8776760 |
Yumen I et al. | Purification, characterization and reconstitution into membranes of the oligomeric c-subunit ring of thermophilic F(o)F(1)-ATP synthase expressed in Escherichia coli. | 2012 | Protein Expr. Purif. | pmid:22381465 |
Powers JD et al. | Purification of avidin from egg whites using affinity-modified unilamellar vesicles. | 1989 | Prog. Clin. Biol. Res. | pmid:2726906 |
Dietrich C et al. | Molecular organization of histidine-tagged biomolecules at self-assembled lipid interfaces using a novel class of chelator lipids. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7568063 |
Watnick PI et al. | Characterization of the transverse relaxation rates in lipid bilayers. | 1990 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2315304 |
Pieta P et al. | Direct visualization of the alamethicin pore formed in a planar phospholipid matrix. | 2012 | Proc. Natl. Acad. Sci. U.S.A. | pmid:23236158 |
Curnow P and Booth PJ | Combined kinetic and thermodynamic analysis of alpha-helical membrane protein unfolding. | 2007 | Proc. Natl. Acad. Sci. U.S.A. | pmid:18025476 |
Baldwin RL et al. | Structural changes of tumor necrosis factor alpha associated with membrane insertion and channel formation. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8577707 |
Herscovitz H et al. | Expression, secretion, and lipid-binding characterization of the N-terminal 17% of apolipoprotein B. | 1991 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1871138 |
Vasudevan SV et al. | Protein folding at the membrane interface, the structure of Nogo-66 requires interactions with a phosphocholine surface. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:20351248 |
Surrey T and Jähnig F | Refolding and oriented insertion of a membrane protein into a lipid bilayer. | 1992 | Proc. Natl. Acad. Sci. U.S.A. | pmid:1502158 |
Sturtevant JM | A scanning calorimetric study of small molecule-lipid bilayer mixtures. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6955783 |
Alecio MR et al. | Use of a fluorescent cholesterol derivative to measure lateral mobility of cholesterol in membranes. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6957857 |
Mateo CR and Douhal A | A coupled proton-transfer and twisting-motion fluorescence probe for lipid bilayers. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9636133 |
Lopez CF et al. | Understanding nature's design for a nanosyringe. | 2004 | Proc. Natl. Acad. Sci. U.S.A. | pmid:15070735 |
Szleifer I et al. | Spontaneous liposome formation induced by grafted poly(ethylene oxide) layers: theoretical prediction and experimental verification. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9448280 |
Chang YC and Bowie JU | Measuring membrane protein stability under native conditions. | 2014 | Proc. Natl. Acad. Sci. U.S.A. | pmid:24367094 |
Tang P and Xu Y | Large-scale molecular dynamics simulations of general anesthetic effects on the ion channel in the fully hydrated membrane: the implication of molecular mechanisms of general anesthesia. | 2002 | Proc. Natl. Acad. Sci. U.S.A. | pmid:12438684 |
Popp CA and Hyde JS | Electron-electron double resonance and saturation-recovery studies of nitroxide electron and nuclear spin-lattice relaxation times and Heisenberg exchange rates: lateral diffusion in dimyristoyl phosphatidylcholine. | 1982 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6283533 |
Subczynski WK et al. | Oxygen permeability of phosphatidylcholine--cholesterol membranes. | 1989 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2543978 |
Pownall HJ et al. | Activation of lecithin:cholesterol acyltransferase by a synthetic model lipid-associating peptide. | 1980 | Proc. Natl. Acad. Sci. U.S.A. | pmid:6774331 |
Chong PL | Evidence for regular distribution of sterols in liquid crystalline phosphatidylcholine bilayers. | 1994 | Proc. Natl. Acad. Sci. U.S.A. | pmid:7937839 |
Villinger S et al. | Functional dynamics in the voltage-dependent anion channel. | 2010 | Proc. Natl. Acad. Sci. U.S.A. | pmid:21148773 |
Radhakrishnan A and McConnell HM | Electric field effect on cholesterol-phospholipid complexes. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10655486 |
Gaffney BJ and Marsh D | High-frequency, spin-label EPR of nonaxial lipid ordering and motion in cholesterol-containing membranes. | 1998 | Proc. Natl. Acad. Sci. U.S.A. | pmid:9789019 |
Klein-Seetharaman J et al. | NMR spectroscopy in studies of light-induced structural changes in mammalian rhodopsin: applicability of solution (19)F NMR. | 1999 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10570143 |
MacDonald RC and Simon SA | Lipid monolayer states and their relationships to bilayers. | 1987 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3473494 |
Radhakrishnan A et al. | Condensed complexes, rafts, and the chemical activity of cholesterol in membranes. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:11050164 |
Serra-Batiste M et al. | Aβ42 assembles into specific β-barrel pore-forming oligomers in membrane-mimicking environments. | 2016 | Proc. Natl. Acad. Sci. U.S.A. | pmid:27621459 |
Peng ZY et al. | Effects of cholesterol or gramicidin on slow and fast motions of phospholipids in oriented bilayers. | 1989 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2479029 |
Kalyanaraman B et al. | Photodynamic action of merocyanine 540 on artificial and natural cell membranes: involvement of singlet molecular oxygen. | 1987 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3033673 |
Prosser RS et al. | Using O2 to probe membrane immersion depth by 19F NMR. | 2000 | Proc. Natl. Acad. Sci. U.S.A. | pmid:10954744 |
de Meyer F and Smit B | Effect of cholesterol on the structure of a phospholipid bilayer. | 2009 | Proc. Natl. Acad. Sci. U.S.A. | pmid:19225105 |
Dornmair K and Jähnig F | Internal dynamics of lactose permease. | 1989 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2690075 |
Spector MS et al. | Chiral molecular self-assembly of phospholipid tubules: a circular dichroism study. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8917523 |
Abbott GW et al. | Interaction between soluble and membrane-embedded potassium channel peptides monitored by Fourier transform infrared spectroscopy. | 2012 | PLoS ONE | pmid:23145073 |
Vilches S et al. | Neurotoxicity of prion peptides mimicking the central domain of the cellular prion protein. | 2013 | PLoS ONE | pmid:23940658 |
Sontag TJ and Reardon CA | Polymorphisms of mouse apolipoprotein A-II alter its physical and functional nature. | 2014 | PLoS ONE | pmid:24520415 |
Fischer NO et al. | Evaluation of nanolipoprotein particles (NLPs) as an in vivo delivery platform. | 2014 | PLoS ONE | pmid:24675794 |